IONS Form 144: 5,635 Shares Proposed Sale

IONS submitted a Form 144 notice reporting a proposed sale of 5,635 shares of Common Stock with an aggregate value of $451,699.00.

Rhea-AI Filing Summary

IONS submitted a Form 144 notice reporting a proposed sale of 5,635 shares of Common Stock with an aggregate value of $451,699.00. The filing lists 165,262,556 shares outstanding as of 06/26/2026 and names Stifel Nicolaus & Company as the broker. The notice also records two cash stock option exercises dated 06/26/2026 for 3,866 and 1,769 shares.

Insights

Securities Attorney

Form 144 records a proposed resale of common stock through a broker.

The filing lists a proposed sale of $451,699.00 worth of 5,635 shares of common stock and names Stifel Nicolaus & Company as the executing broker. Form 144 is a notice of intent to sell under resale rules, not a confirmation of completed sales.

Timing and actual execution are not shown; subsequent trade confirmations or amended filings will report completed transactions or changes. Review future broker reports or Form 4/Form 5 filings for final disposition details.

Key Figures

Proposed shares to be sold: 5,635 shares Aggregate value: $451,699.00 Shares outstanding: 165,262,556 +2 more

5 metrics

Proposed shares to be sold 5,635 shares listed in the Form 144 notice

Aggregate value $451,699.00 aggregate dollar amount shown alongside proposed sale

Shares outstanding 165,262,556 listed with date <date>06/26/2026</date>

Option exercise 1 3,866 shares Stock Option Exercise dated <date>06/26/2026</date>

Option exercise 2 1,769 shares Stock Option Exercise dated <date>06/26/2026</date>

Key Terms

Form 144, Stock Option Exercise, Broker

3 terms

Form 144 regulatory

"144: Securities To Be Sold Common Stock | 5635 | 451699.00"

Form 144 is a document that investors must file with the government when they plan to sell a large number of shares of a company's stock. It helps ensure transparency so everyone knows how many shares are being sold and when, which can impact the stock's price.

Stock Option Exercise financial

"Common Stock | 01/04/2021 | Stock Option Exercise"

A stock option exercise is the act of using a previously granted right to buy shares of a company's stock at a specific, predetermined price by paying that price and receiving the shares. It matters to investors because exercising changes who owns the shares (which can dilute existing ownership), can trigger taxable events and shift potential gains or losses, and affects voting power and the company’s outstanding share count—like turning a voucher into an actual product that becomes part of circulating supply.

Broker market

"Stifel Nicolaus & Company Inc 501 N Broadway St. Louis MO 63102"

A broker is a licensed professional or firm that helps investors buy and sell financial assets by executing trades on their behalf, acting like a marketplace agent or matchmaker between buyers and sellers. Brokers matter to investors because they provide access to markets, handle order execution and paperwork, and can offer research or advice—services that affect trade speed, costs, and the quality of investment decisions.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What does IONS' Form 144 disclose about proposed sales?

The Form 144 discloses a proposed sale of 5,635 shares of common stock valued at $451,699.00. It lists Stifel Nicolaus & Company as the broker and includes two option exercises totaling 5,635 shares dated 06/26/2026.

Does the Form 144 show the shares have already been sold for IONS?

No. Form 144 is a notice of intent; it does not confirm completed trades. Execution status and final sale details would appear in subsequent broker confirmations or insider filings such as Form 4 or Form 5.

How many shares outstanding does the filing list for IONS?

The filing lists total shares outstanding as 165,262,556 with a date of 06/26/2026. That figure appears alongside the proposed sale and market column in the filing excerpt.

What option exercises are shown in the filing for IONS?

The excerpt records two cash stock option exercises dated 06/26/2026 for 3,866 shares and 1,769 shares. Those exercised shares align numerically with the proposed resale quantity shown.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 06/26/2026 - 05:48 PM EDT Learn about SEC filing dates

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK	0001961885
Filer CCC	XXXXXXXX
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer	IONIS PHARMACEUTICALS INC
SEC File Number	000-19125
Address of Issuer	2855 GAZELLE COURT CARLSBAD CALIFORNIA 92010
Phone	7609319200
Name of Person for Whose Account the Securities are To Be Sold	Baroldi Mariana
See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.
Relationship to Issuer	Member of immediate family of any of the foregoing

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common Stock	Stifel Nicolaus & Company Inc 501 N Broadway St. Louis MO 63102	5635	451699.00	165262556	06/26/2026	Nasdaq

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common Stock	01/04/2021	Stock Option Exercise	Issuer			3866	06/26/2026	Cash
Common Stock	01/03/2022	Stock Option Exercise	Issuer			1769	06/26/2026	Cash

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Nothing to Report

144: Remarks and Signature

Remarks
Date of Notice	06/26/2026
Date of Plan Adoption or Giving of Instruction, If Relying on Rule 10b5-1	11/25/2025
ATTENTION:
The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.
Signature	/s/ James Weimer, as a duly authorized representative of STIFEL, as attorney-in-fact for Mariana Baroldi
ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)