STOCK TITAN

Ionis (IONS) CSO Frank Bennett sells shares, shifts 15,000 into family trust

Filing Impact
(Very High)
Filing Sentiment
(Negative)
Form Type
4

Rhea-AI Filing Summary

Ionis Pharmaceuticals EVP and Chief Scientific Officer Frank Bennett reported insider transactions involving company stock. On July 7, he executed open-market sales of 15,000 shares held indirectly through a trust at a weighted average price of $85.462 per share and 5,536 shares held directly at a weighted average price of $83.579 per share, under a pre-arranged Rule 10b5-1 trading plan. He also transferred 15,000 shares from direct to indirect ownership via a family trust and reported 15,000 restricted stock units that vested on January 15, 2026 and were paid in common shares. Following these transactions, he holds 75,018 shares directly, 15,000 shares indirectly through the trust, and 12,109 restricted stock units.

Positive

  • None.

Negative

  • None.
Insider BENNETT C FRANK
Role EVP, Chief Scientific Officer
Sold 20,536 shs ($1.74M)
Type Security Shares Price Value
Other Restricted Stock Unit 15,000 $0.00 --
Sale Common Stock 5,536 $83.579 $463K
Other Common Stock 15,000 $0.00 --
Sale Common Stock 15,000 $85.462 $1.28M
Holdings After Transaction: Restricted Stock Unit — 12,109 shares (Direct, null); Common Stock — 75,018 shares (Direct, null); Common Stock — 15,000 shares (Indirect, by Trust)
Footnotes (1)
  1. Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on March 31, 2026. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $83.070 to $84.065 inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc. any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) on this Form 4. Represents a transfer of 15,000 shares of common stock from direct ownership to indirect ownership held by the Clarence Frank Bennett TTEE Bennett Living Trust Dated 3/12/2008, of which the reporting person is the co-trustee with spouse. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $85.015 to $85.730 inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc. any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (3) on this Form 4. Restricted Stock Unit vested on January 15, 2026. Upon vesting, the restricted stock unit was paid out in whole shares of Ionis common stock.
Indirect shares sold 15,000 shares Open-market sale via trust at $85.462 weighted average on July 7, 2026
Direct shares sold 5,536 shares Open-market sale at $83.579 weighted average on July 7, 2026
Direct holdings after transaction 75,018 shares Common stock held directly following July 7, 2026 transactions
Indirect holdings after transfer 15,000 shares Common stock held indirectly by Bennett Living Trust after transfer
Remaining RSUs 12,109 units Restricted stock units outstanding after vesting event
Vested RSUs 15,000 units Restricted stock units vested January 15, 2026 and paid in shares
Rule 10b5-1 Trading Plan regulatory
"Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on March 31, 2026."
A Rule 10b5-1 trading plan is a pre-arranged schedule that allows company insiders to buy or sell stock at specific times, even if they have inside information. It helps prevent accusations of unfair trading by making these transactions look planned and transparent, rather than sneaky or illegal.
Restricted Stock Unit financial
"Restricted Stock Unit vested on January 15, 2026. Upon vesting, the restricted stock unit was paid out in whole shares of Ionis common stock."
A restricted stock unit is a promise from a company to give an employee shares of stock after certain conditions are met, like staying with the company for a set amount of time. It’s like earning a bonus that turns into company stock once you’ve proven your commitment, making it a way to motivate and reward employees.
weighted average price financial
"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $83.070 to $84.065 inclusive."
Weighted average price is the average price of a security where each trade or component is counted according to its size, so bigger trades pull the average more than smaller ones. Think of it like calculating the average cost of a grocery haul where items you bought more of have greater influence on the final per-item cost. Investors use it to understand the true average price paid or received, judge execution quality, and compare trading performance against market movement.
indirect ownership financial
"Represents a transfer of 15,000 shares of common stock from direct ownership to indirect ownership held by the Clarence Frank Bennett TTEE Bennett Living Trust Dated 3/12/2008."
other acquisition or disposition regulatory
"transaction_code_description: "Other acquisition or disposition" for J-code transactions in common stock and restricted stock units."
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FAQ

What insider transactions did Ionis (IONS) executive Frank Bennett report?

Frank Bennett reported selling 15,000 Ionis shares indirectly through a trust and 5,536 shares directly in open-market transactions. He also recorded a 15,000-share transfer to a family trust and the vesting of 15,000 restricted stock units into common shares.

How many Ionis (IONS) shares did Frank Bennett sell and at what prices?

Frank Bennett sold 15,000 Ionis shares indirectly at a weighted average price of $85.462 and 5,536 shares directly at $83.579. Both were open-market transactions, with prices representing weighted averages across multiple individual trades within specified ranges.

Were Frank Bennett’s Ionis (IONS) stock sales made under a Rule 10b5-1 plan?

Yes. The filing states that the shares were sold pursuant to a Rule 10b5-1 trading plan adopted by Frank Bennett on March 31, 2026. Such pre-arranged plans automate trading and can reduce the significance of timing for interpreting insider activity.

How did Frank Bennett’s holdings in Ionis (IONS) change after these transactions?

After the reported transactions, Frank Bennett holds 75,018 Ionis common shares directly and 15,000 shares indirectly through a family trust. He also reports ownership of 12,109 restricted stock units, which represent rights to receive additional Ionis common shares in the future.

What happened to Frank Bennett’s Ionis (IONS) restricted stock units?

A block of 15,000 restricted stock units vested on January 15, 2026 and was paid out in whole shares of Ionis common stock. After this vesting event, Bennett reports remaining holdings of 12,109 restricted stock units in the filing’s derivative securities table.
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
BENNETT C FRANK

(Last)(First)(Middle)
2855 GAZELLE COURT

(Street)
CARLSBAD CALIFORNIA 92010

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
IONIS PHARMACEUTICALS INC [ IONS ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director10% Owner
XOfficer (give title below)Other (specify below)
EVP, Chief Scientific Officer
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
07/07/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock07/07/2026S5,536(1)D$83.579(2)75,018D
Common Stock07/07/2026J15,000(3)A$0.015,000Iby Trust
Common Stock07/07/2026S15,000(1)D$85.462(4)0Iby Trust
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Restricted Stock Unit$0.007/07/2026J15,000 (5) (5)Common Stock15,000$0.012,109D
Explanation of Responses:
1. Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on March 31, 2026.
2. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $83.070 to $84.065 inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc. any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) on this Form 4.
3. Represents a transfer of 15,000 shares of common stock from direct ownership to indirect ownership held by the Clarence Frank Bennett TTEE Bennett Living Trust Dated 3/12/2008, of which the reporting person is the co-trustee with spouse.
4. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $85.015 to $85.730 inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc. any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (3) on this Form 4.
5. Restricted Stock Unit vested on January 15, 2026. Upon vesting, the restricted stock unit was paid out in whole shares of Ionis common stock.
By: Patrick R. O'Neil, attorney-in-fact For: C. Frank Bennett07/09/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)