[10-Q] IQVIA HOLDINGS INC. Quarterly Earnings Report

Rhea-AI Filing Summary

IQVIA Holdings Inc. reported third‑quarter results with steady growth and active balance sheet management. Q3 2025 revenue was $4.1 billion versus $3.896 billion a year ago, and diluted EPS was $1.93 compared with $1.55. Segment revenue reached $1.631 billion in Technology & Analytics Solutions, $2.260 billion in Research & Development Solutions, and $209 million in Contract Sales & Medical Solutions. Q3 income from operations was $553 million. For the first nine months, revenue totaled $11.946 billion and diluted EPS was $4.86.

Operating cash flow for the nine months was $1.919 billion, supporting $1.032 billion of share repurchases (6.4 million shares). The company issued $2.0 billion of 6.250% senior notes due 2032 and amended its credit facilities, including a $1.985 billion Term B-5 loan to refinance prior tranches. Total debt principal was $15.034 billion and cash was $1.814 billion at quarter‑end. Remaining performance obligations were $34.4 billion, with about 30% expected to convert within 12 months. Goodwill increased to $15.948 billion, reflecting acquisitions. Common shares outstanding were 170.3 million as of October 20, 2025. Legal disputes with Veeva were fully resolved in August 2025 with no payment by either party.

Insights

Credit & capital markets analyst

Steady growth, active refinancing, and sizable RPO underpin visibility.

IQVIA delivered Q3 revenue of $4,100M and diluted EPS of $1.93. Segment mix remained R&D‑heavy, which aligns with its long‑cycle clinical services. Year‑to‑date operating cash flow of $1,919M supported $1,032M in buybacks, lowering the basic weighted average share count to 170.2M in Q3 from 182.1M a year ago.

On capital structure, the company issued $2,000M 6.250% notes due 2032 and added a $1,985M Term B‑5 facility, while repaying maturing 2025 Euro notes. Gross debt principal stands at $15,034M, with a clear maturity ladder detailed through 2032. Cross‑currency and interest rate hedges are in place; their OCI movements reflect market conditions.

Commercial visibility is supported by remaining performance obligations of $34.4B, with about 30% expected within twelve months. Actual revenue conversion depends on project execution and milestone timing. Restructuring costs of $81M year‑to‑date indicate ongoing alignment efforts; their benefits and timing are not quantified in this excerpt.

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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

______________________________________________________

FORM 10-Q

_________________________________________________________

(Mark One)

☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended September 30, 2025

or

☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the transition period from            to             .

Commission File Number: 001-35907

_________________________________________________________

IQVIA HOLDINGS INC.

(Exact name of registrant as specified in its charter)

_________________________________________________________

Delaware						27-1341991
(State or other jurisdiction of incorporation or organization)						(I.R.S. Employer Identification Number)

2400 Ellis Rd., Durham, North Carolina 27703

(Address of principal executive office and Zip Code)

(919) 998-2000

(Registrant’s telephone number, including area code)

_________________________________________________________

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.    Yes x    No ¨

Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files).    Yes x    No ¨

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

Large accelerated filer			x			Accelerated filer			☐
Non-accelerated filer			☐			Smaller reporting company			☐
						Emerging growth company			☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.    ¨

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).    Yes ☐    No x

Securities registered pursuant to Section 12(b) of the Act:

Title of Each Class

Trading Symbol

Name of Each Exchange on which Registered

Common Stock, par value $0.01 per share

IQV

New York Stock Exchange

Indicate the number of shares outstanding of each of the issuer’s classes of Common Stock, as of the latest practicable date.

Class						Number of Shares Outstanding
Common Stock $0.01 par value						170.3 million shares outstanding as of October 20, 2025

Table of contents

IQVIA HOLDINGS INC.

FORM 10-Q

TABLE OF CONTENTS

						Page
PART I—FINANCIAL INFORMATION						3
Item 1.			Financial Statements (unaudited)			3
			Condensed Consolidated Statements of Income for the three and nine months ended September 30, 2025 and 2024			3
			Condensed Consolidated Statements of Comprehensive Income for the three and nine months ended September 30, 2025 and 2024			4
			Condensed Consolidated Balance Sheets as of September 30, 2025 and December 31, 2024			5
			Condensed Consolidated Statements of Cash Flows for the nine months ended September 30, 2025 and 2024			6
			Condensed Consolidated Statements of Stockholders’ Equity for the three and nine months ended September 30, 2025 and 2024			7
			Notes to Condensed Consolidated Financial Statements			9
Item 2.			Management’s Discussion and Analysis of Financial Condition and Results of Operations			24
Item 3.			Quantitative and Qualitative Disclosures About Market Risk			37
Item 4.			Controls and Procedures			37
PART II—OTHER INFORMATION						39
Item 1.			Legal Proceedings			39
Item 1A.			Risk Factors			39
Item 2.			Unregistered Sales of Equity Securities and Use of Proceeds			39
Item 5.			Other Information			40
Item 6.			Exhibits			41
SIGNATURES						42

2

Table of contents

PART I—FINANCIAL INFORMATION

Item 1. Financial Statements

IQVIA HOLDINGS INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF INCOME

(unaudited)

						Three Months Ended September 30,												Nine Months Ended September 30,
(in millions, except per share data)						2025						2024						2025						2024
Revenues						$	4,100					$	3,896					$	11,946					$	11,447
Cost of revenues, exclusive of depreciation and amortization						2,727						2,518						7,952						7,450
Selling, general and administrative expenses						514						522						1,531						1,539
Depreciation and amortization						286						278						827						811
Restructuring costs						20						28						81						71
Income from operations						553						550						1,555						1,576
Interest income						(13)						(13)						(34)						(36)
Interest expense						189						170						536						499
Loss on extinguishment of debt						—						—						4						—
Other (income) expense, net						(31)						44						(5)						(12)
Income before income taxes and equity in earnings (losses) of unconsolidated affiliates						408						349						1,054						1,125
Income tax expense						76						65						193						189
Income before equity in earnings (losses) of unconsolidated affiliates						332						284						861						936
Equity in earnings (losses) of unconsolidated affiliates						—						1						(14)						—
Net income						332						285						847						936
Net income attributable to noncontrolling interests						(1)						—						(1)						—
Net income attributable to IQVIA Holdings Inc.						$	331					$	285					$	846					$	936
Earnings per share attributable to common stockholders:
Basic						$	1.94					$	1.57					$	4.90					$	5.14
Diluted						$	1.93					$	1.55					$	4.86					$	5.08
Weighted average common shares outstanding:
Basic						170.2						182.1						172.6						182.1
Diluted						171.7						184.2						174.1						184.3

The accompanying notes are an integral part of these condensed consolidated financial statements.

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IQVIA HOLDINGS INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME

(unaudited)

						Three Months Ended September 30,												Nine Months Ended September 30,
(in millions)						2025						2024						2025						2024
Net income						$	332					$	285					$	847					$	936
Comprehensive income adjustments:
Unrealized (losses) gains on derivative instruments, net of income tax (benefit) expense of $(2),$(14),$(8),$2						(5)						(41)						(26)						8
Defined benefit plan adjustments, net of income tax (benefit) of $—, $—,$(1),$—						—						(1)						(3)						(1)
Foreign currency translation, net of income tax (benefit) expense of $(4),$(37),$(143),$13						(38)						173						143						62
Reclassification adjustments:
Reclassifications on derivative instruments included in net income, net of income tax (expense) of $—,$(3),$(1),$(10)						(3)						(8)						(4)						(28)
Comprehensive income						286						408						957						$	977
Comprehensive income attributable to noncontrolling interests						(1)						—						(1)						—
Comprehensive income attributable to IQVIA Holdings Inc.						$	285					$	408					$	956					$	977

The accompanying notes are an integral part of these condensed consolidated financial statements.

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IQVIA HOLDINGS INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED BALANCE SHEETS

(unaudited)

(in millions, except per share data)						September 30, 2025						December 31, 2024
ASSETS
Current assets:
Cash and cash equivalents						$	1,814					$	1,702
Trade accounts receivable and unbilled services, net						3,269						3,204
Prepaid expenses						177						154
Income taxes receivable						45						36
Investments in debt, equity and other securities						158						141
Other current assets and receivables						516						592
Total current assets						5,979						5,829
Property and equipment, net						525						535
Operating lease right-of-use assets						299						238
Investments in debt, equity and other securities						130						108
Investments in unconsolidated affiliates						275						266
Goodwill						15,948						14,710
Other identifiable intangibles, net						4,707						4,499
Deferred income taxes						390						194
Deposits and other assets, net						474						520
Total assets						$	28,727					$	26,899
LIABILITIES AND STOCKHOLDERS’ EQUITY
Current liabilities:
Accounts payable and accrued expenses						$	3,550					$	3,684
Unearned income						2,160						1,779
Income taxes payable						119						156
Current portion of long-term debt						2,164						1,145
Other current liabilities						515						193
Total current liabilities						8,508						6,957
Long-term debt, less current portion						12,793						12,838
Deferred income taxes						207						196
Operating lease liabilities						233						173
Other liabilities						698						668
Total liabilities						22,439						20,832
Commitments and contingencies (Note 8)
Stockholders’ equity:
Common stock and additional paid-in capital, 400.0 shares authorized as of September 30, 2025 and December 31, 2024, $0.01 par value, 258.8 shares issued and 170.3 shares outstanding as of September 30, 2025; 258.2 shares issued and 176.1 shares outstanding as of December 31, 2024						11,321						11,143
Retained earnings						6,911						6,065
Treasury stock, at cost, 88.5 and 82.1 shares as of September 30, 2025 and December 31, 2024, respectively						(11,144)						(10,103)
Accumulated other comprehensive loss						(928)						(1,038)
Equity attributable to IQVIA Holdings Inc.’s stockholders						6,160						6,067
Noncontrolling interests						128						—
Total stockholders’ equity						6,288						6,067
Total liabilities and stockholders’ equity						$	28,727					$	26,899

The accompanying notes are an integral part of these condensed consolidated financial statements.

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IQVIA HOLDINGS INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

(unaudited)

						Nine Months Ended September 30,
(in millions)						2025						2024
Operating activities:
Net income						$	847					$	936
Adjustments to reconcile net income to cash provided by operating activities:
Depreciation and amortization						827						811
Amortization of debt issuance costs and discount						17						16
Stock-based compensation						187						158
Losses from unconsolidated affiliates						14						—
Gain on investments, net						(20)						(29)
Benefit from deferred income taxes						(132)						(114)
Changes in operating assets and liabilities:
Change in accounts receivable, unbilled services and unearned income						442						259
Change in other operating assets and liabilities						(263)						(206)
Net cash provided by operating activities						1,919						1,831
Investing activities:
Acquisition of property, equipment and software						(429)						(438)
Acquisition of businesses, net of cash acquired						(798)						(649)
Sales of marketable securities, net						2						—
Investments in unconsolidated affiliates, net of payments received						(28)						(68)
Investments in debt and equity securities						(20)						(2)
Proceeds from sale of property, equipment and software						75						25
Other						(3)						(2)
Net cash used in investing activities						(1,201)						(1,134)
Financing activities:
Proceeds from issuance of debt						3,985						—
Payment of debt issuance costs						(34)						—
Repayment of debt and principal payments on finance leases						(2,676)						(130)
Proceeds from revolving credit facility						1,375						685
Repayment of revolving credit facility						(2,200)						(785)
Payments related to employee stock incentive plans						(66)						(61)
Repurchase of common stock						(1,032)						(200)
Contingent consideration and deferred purchase price payments						(26)						(12)
Other						(11)						—
Net cash used in financing activities						(685)						(503)
Effect of foreign currency exchange rate changes on cash						79						2
Increase in cash and cash equivalents						112						196
Cash and cash equivalents at beginning of period						1,702						1,376
Cash and cash equivalents at end of period						$	1,814					$	1,572

The accompanying notes are an integral part of these condensed consolidated financial statements.

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IQVIA HOLDINGS INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY

(unaudited)

(in millions)						Common Stock Shares						Treasury Stock Shares						Common Stock						Additional Paid-In Capital						Retained Earnings						Treasury Stock						Accumulated Other Comprehensive (Loss) Income						Noncontrolling Interests						Total
Balance, December 31, 2024						258.2						(82.1)						$	3					$	11,140					$	6,065					$	(10,103)					$	(1,038)					$	—					$	6,067
Issuance of common stock						0.3						—						—						(35)						—						—						—						—						(35)
Repurchase of common stock, net of tax						—						(2.3)						—						—						—						(429)						—						—						(429)
Stock-based compensation						—						—						—						65						—						—						—						—						65
Acquisitions related noncontrolling interests						—						—						—						—						—						—						—						8						8
Net income						—						—						—						—						249						—						—						—						249
Unrealized losses on derivative instruments, net of tax						—						—						—						—						—						—						(17)						—						(17)
Defined benefit plan adjustments, net of tax						—						—						—						—						—						—						(3)						—						(3)
Foreign currency translation, net of tax						—						—						—						—						—						—						79						—						79
Reclassification adjustments, net of tax						—						—						—						—						—						—						1						—						1
Balance, March 31, 2025						258.5						(84.4)						3						11,170						6,314						(10,532)						(978)						8						5,985
Issuance of common stock						—						—						—						—						—						—						—						—						—
Repurchase of common stock, net of tax						—						(4.1)						—						—						—						(613)						—						—						(613)
Stock-based compensation						—						—						—						52						—						—						—						—						52
Net income						—						—						—						—						266						—						—						—						266
Unrealized gains on derivative instruments, net of tax						—						—						—						—						—						—						(4)						—						(4)
Foreign currency translation, net of tax						—						—						—						—						—						—						102						—						102
Reclassification adjustments, net of tax						—						—						—						—						—						—						(2)						—						(2)
Balance, June 30, 2025						258.5						(88.5)						3						11,222						6,580						(11,145)						(882)						8						5,786
Issuance of common stock						0.3						—						—						45						—						—						—						—						45
Tax on repurchase of common stock						—						—						—						—						—						1						—						—						1
Stock-based compensation						—						—						—						51						—						—						—						—						51
Acquisitions related noncontrolling interests						—						—						—						—						—						—						—						119						119
Net income						—						—						—						—						331						—						—						1						332
Unrealized losses on derivative instruments, net of tax						—						—						—						—						—						—						(5)						—						(5)
Foreign currency translation, net of tax						—						—						—						—						—						—						(38)						—						(38)
Reclassification adjustments, net of tax						—						—						—						—						—						—						(3)						—						(3)
Balance, September 30, 2025						258.8						(88.5)						$	3					$	11,318					$	6,911					$	(11,144)					$	(928)					$	128					$	6,288

The accompanying notes are an integral part of these condensed consolidated financial statements.

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IQVIA HOLDINGS INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY

(unaudited)

(in millions)						Common Stock Shares						Treasury Stock Shares						Common Stock						Additional Paid-In Capital						Retained Earnings						Treasury Stock						Accumulated Other Comprehensive (Loss) Income						Noncontrolling Interests						Total
Balance, December 31, 2023						257.2						(75.7)						$	3					$	11,025					$	4,692					$	(8,741)					$	(867)					$	—					$	6,112
Issuance of common stock						0.7						—						—						(61)						—						—						—						—						(61)
Stock-based compensation						—						—						—						49						—						—						—						—						49
Net income						—						—						—						—						288						—						—						—						288
Unrealized gains on derivative instruments, net of tax						—						—						—						—						—						—						34						—						34
Foreign currency translation, net of tax						—						—						—						—						—						—						(69)						—						(69)
Reclassification adjustments, net of tax						—						—						—						—						—						—						(9)						—						(9)
Balance, March 31, 2024						257.9						(75.7)						3						11,013						4,980						(8,741)						(911)						—						6,344
Issuance of common stock						0.1						—						—						1						—						—						—						—						1
Stock-based compensation						—						—						—						44						—						—						—						—						44
Net income						—						—						—						—						363						—						—						—						363
Unrealized gains on derivative instruments, net of tax						—						—						—						—						—						—						15						—						15
Foreign currency translation, net of tax						—						—						—						—						—						—						(42)						—						(42)
Reclassification adjustments, net of tax						—						—						—						—						—						—						(11)						—						(11)
Balance, June 30, 2024						258.0						(75.7)						3						11,058						5,343						(8,741)						(949)						—						6,714
Issuance of common stock						0.1						—						—						(1)						—						—						—						—						(1)
Repurchase of common stock, net of tax						—						(0.8)						—						—						—						(200)						—						—						(200)
Stock-based compensation						—						—						—						46						—						—						—						—						46
Net income						—						—						—						—						285						—						—						—						285
Unrealized gains on derivative instruments, net of tax						—						—						—						—						—						—						(41)						—						(41)
Defined benefit plan adjustments, net of tax						—						—						—						—						—						—						(1)						—						(1)
Foreign currency translation, net of tax						—						—						—						—						—						—						173						—						173
Reclassification adjustments, net of tax						—						—						—						—						—						—						(8)						—						(8)
Balance, September 30, 2024						258.1						(76.5)						$	3					$	11,103					$	5,628					$	(8,941)					$	(826)					$	—					$	6,967

The accompanying notes are an integral part of these condensed consolidated financial statements.

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IQVIA HOLDINGS INC. AND SUBSIDIARIES

Notes to Condensed Consolidated Financial Statements

(unaudited)

1. Summary of Significant Accounting Policies

The Company

IQVIA Holdings Inc. (together with its subsidiaries, the “Company” or “IQVIA”) is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. With approximately 91,000 employees, the Company conducts business in more than 100 countries.

Unaudited Interim Financial Information

The accompanying unaudited condensed consolidated financial statements of the Company have been prepared in accordance with generally accepted accounting principles in the United States of America (“GAAP”) for interim financial information. Accordingly, they do not include all of the information and notes required by GAAP for complete financial statements. In the opinion of management, all adjustments (consisting of normal recurring adjustments) considered necessary for a fair statement of the Company’s financial condition and results of operations have been included. Operating results for the periods presented are not necessarily indicative of the results that may be expected for the year ending December 31, 2025. As such, the information included in this Quarterly Report on Form 10-Q should be read in conjunction with the Company’s audited consolidated financial statements included in the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2024. The balance sheet as of December 31, 2024 has been derived from the audited consolidated financial statements of the Company, but does not include all the disclosures required by GAAP.

Recently Issued Accounting Standards

Accounting pronouncements recently adopted

In November 2023, the Financial Accounting Standards Board ("FASB") issued Accounting Standards Update ("ASU") 2023-07, Segment Reporting (Topic 280): Improvements to Reportable Segment Disclosures, to improve reportable segment disclosure requirements. The new guidance requires disclosure of significant segment expenses that are regularly provided to the chief operating decision maker and included in the reported measure of segment profit or loss. It does not change the definition of a segment or the guidance for determining reportable segments. The new guidance was effective for the Company in the annual period beginning January 1, 2024, and in 2025 for interim periods. The adoption of this new accounting guidance for the annual period beginning January 1, 2024, and for the three and nine months ended September 30, 2025, did not have a material effect on the Company's disclosures within the consolidated financial statements.

Accounting pronouncements issued but not adopted as of September 30, 2025

In December 2023, the FASB issued ASU 2023-09, Income Taxes (Topic 740): Improvements to Income Tax Disclosures, to enhance the transparency and decision usefulness of income tax disclosures. The amendments in this ASU require additional disclosures about income taxes, primarily focused on the disclosure of income taxes paid and the rate reconciliation table. The new guidance is effective for the Company in the annual period beginning January 1, 2025. The Company is assessing the impacts of this ASU on its disclosures within the consolidated financial statements.

In November 2024, the FASB issued ASU 2024-03, Disaggregation of Income Statement Expenses (DISE), to improve the disclosures about an entity's expenses and address requests from investors for more detailed information about the types of expenses in commonly presented expense captions. The new guidance requires additional information about specific expense categories in the notes to financial statements at interim and annual reporting periods, and will be effective for the Company in the annual period beginning January 1, 2027, and interim periods beginning January 1, 2028. The Company is assessing the impacts of this ASU on its disclosures within the consolidated financial statements.

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In September 2025, the FASB issued ASU 2025-06, Intangibles-Goodwill and Other-Internal-Use Software (Subtopic 350-40): Targeted Improvements to the Accounting for Internal-Use Software, to modernize the accounting for internal-use software costs. The new guidance amends the existing standard that refers to various stages of a software development project to align better with current software development methods. Under the new guidance, entities will start capitalizing eligible costs when management has authorized and committed to funding the software project, and it is probable that the project will be completed and the software will be used to perform the function intended. In evaluating whether it is probable the project will be completed, an entity is required to consider whether there is significant uncertainty associated with the development activities of the software. The new guidance is effective for the Company in the annual period beginning January 1, 2028. The Company is assessing the impacts of this ASU on its consolidated financial statements.

2. Revenues by Geography, Concentration of Credit Risk and Remaining Performance Obligations

The following tables represent revenues by geographic region and reportable segment for the three and nine months ended September 30, 2025 and 2024:

			Three Months Ended September 30, 2025
(in millions)						Technology & Analytics Solutions						Research & Development Solutions						Contract Sales & Medical Solutions						Total
Revenues:
Americas						$	824					$	1,039					$	70					$	1,933
Europe and Africa						652						570						75						1,297
Asia-Pacific						155						651						64						870
Total revenues						$	1,631					$	2,260					$	209					$	4,100

						Three Months Ended September 30, 2024
(in millions)						Technology & Analytics Solutions						Research & Development Solutions						Contract Sales & Medical Solutions						Total
Revenues:
Americas						$	797					$	969					$	72					$	1,838
Europe and Africa						626						607						54						1,287
Asia-Pacific						131						586						54						771
Total revenues						$	1,554					$	2,162					$	180					$	3,896

			Nine Months Ended September 30, 2025
(in millions)						Technology & Analytics Solutions						Research & Development Solutions						Contract Sales & Medical Solutions						Total
Revenues:
Americas						$	2,437					$	3,030					$	208					$	5,675
Europe and Africa						1,915						1,659						188						3,762
Asia-Pacific						453						1,874						182						2,509
Total revenues						$	4,805					$	6,563					$	578					$	11,946

						Nine Months Ended September 30, 2024
(in millions)						Technology & Analytics Solutions						Research & Development Solutions						Contract Sales & Medical Solutions						Total
Revenues:
Americas						$	2,323					$	2,969					$	211					$	5,503
Europe and Africa						1,757						1,699						166						3,622
Asia-Pacific						422						1,736						164						2,322
Total revenues						$	4,502					$	6,404					$	541					$	11,447

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No individual customer represented 10% or more of consolidated revenues for the three and nine months ended September 30, 2025 or 2024.

Transaction Price Allocated to the Remaining Performance Obligations

As of September 30, 2025, approximately $34.4 billion of revenues are expected to be recognized in the future from remaining performance obligations. The Company expects to recognize revenues on approximately 30% of these remaining performance obligations over the next twelve months, on approximately 85% over the next five years, with the balance recognized thereafter. Most of the Company's remaining performance obligations where revenues are expected to be recognized beyond the next twelve months are for service contracts for clinical research in the Company's Research & Development Solutions segment. The customer contract transaction price allocated to the remaining performance obligations differs from backlog in that it does not include wholly unperformed contracts under which the customer has a unilateral right to cancel the arrangement.

3. Trade Accounts Receivable, Unbilled Services and Unearned Income

Trade accounts receivables and unbilled services consist of the following:

(in millions)						September 30, 2025						December 31, 2024
Trade accounts receivable						$	1,423					$	1,390
Unbilled services						1,891						1,856
Trade accounts receivable and unbilled services						3,314						3,246
Allowance for doubtful accounts						(45)						(42)
Trade accounts receivable and unbilled services, net						$	3,269					$	3,204

Unbilled services and unearned income were as follows:

(in millions)						September 30, 2025						December 31, 2024						Change
Unbilled services						$	1,891					$	1,856					$	35
Unearned income						(2,160)						(1,779)						(381)
Net balance						$	(269)					$	77					$	(346)

Unbilled services, which is comprised of approximately 68% and 69% of unbilled receivables and 32% and 31% of contract assets as of September 30, 2025 and December 31, 2024, increased by $35 million as compared to December 31, 2024. Contract assets are unbilled services for which invoicing is based on the timing of certain milestones related to service contracts for clinical research whereas unbilled receivables are billable upon the passage of time. Unearned income increased by $381 million over the same period resulting in a decrease of $346 million in the net balance of unbilled services and unearned income between September 30, 2025 and December 31, 2024. The change in the net balance is driven by the difference in timing of revenue recognition in accordance with Accounting Standards Codification ("ASC") 606, Revenue from Contracts with Customers, primarily related to the Company’s Research & Development Solutions contracts (which is based on the percentage of costs incurred) versus the timing of invoicing, which is based on certain milestones.

The majority of the unearned income balance as of the beginning of the year is expected to be recognized in revenues during the year ended December 31, 2025.

Bad debt expense recognized on the Company’s trade accounts receivable was immaterial for the three and nine months ended September 30, 2025 and 2024.

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Accounts Receivable Factoring Arrangements

The Company has accounts receivable factoring agreements to sell certain eligible unsecured trade accounts receivable, either based on automatic arrangements or at its option, without recourse, to unrelated third-party financial institutions for cash. During the nine months ended September 30, 2025, through its accounts receivable factoring arrangements that the Company utilizes most frequently, the Company factored approximately $550 million of customer invoices on a non-recourse basis and received approximately $546 million in cash proceeds from the sales. During the nine months ended September 30, 2024, through these same accounts receivable factoring arrangements, the Company factored approximately $531 million of customer invoices on a non-recourse basis and received approximately $520 million in cash proceeds from the sales. The fees associated with these transactions were immaterial. The Company has other accounts receivable arrangements for which the activity associated with them is immaterial.

4. Goodwill

The following is a summary of goodwill by reportable segment for the nine months ended September 30, 2025:

(in millions)						Technology & Analytics Solutions						Research & Development Solutions						Contract Sales & Medical Solutions						Consolidated
Balance as of December 31, 2024						$	11,957					$	2,608					$	145					$	14,710
Business combinations						174						402						20						596
Impact of foreign currency fluctuations and other						617						22						3						642
Balance as of September 30, 2025						$	12,748					$	3,032					$	168					$	15,948

5. Derivatives

The fair values of the Company’s derivative instruments and the line items on the accompanying condensed consolidated balance sheets to which they were recorded are summarized in the following table:

(in millions)						Balance Sheet Classification						September 30, 2025																		December 31, 2024
												Assets						Liabilities						Notional						Assets						Liabilities						Notional
Derivatives designated as hedging instruments:
Interest rate swaps						Other current liabilities						$	—					$	50					$	2,474					$	—					$	5					$	2,485
Cross-currency swaps						Other current liabilities and other assets						—						340						2,724						39						—						2,735
Foreign exchange forward contracts						Other current assets and other current liabilities						5						1						130						—						2						108
Total derivatives												$	5					$	391											$	39					$	7

The pre-tax effect of the Company’s cash flow hedging instruments on other comprehensive income is summarized in the following table:

						Three Months Ended September 30,												Nine Months Ended September 30,
(in millions)						2025						2024						2025						2024
Interest rate swaps						$	(5)					$	(70)					$	(45)					$	(32)
Foreign exchange forward contracts						(5)						4						6						4
Total						$	(10)					$	(66)					$	(39)					$	(28)

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The Company expects approximately $6 million of pre-tax unrealized gains related to its foreign exchange contracts and interest rate derivatives included in accumulated other comprehensive (loss) income (“AOCI”) as of September 30, 2025 to be reclassified into earnings within the next twelve months. For the three and nine months ended September 30, 2025 and 2024, the total amount, net of income taxes, of the cash flow hedge effect on the accompanying condensed consolidated statements of income was $3 million and $8 million, and $4 million and $28 million, respectively.

During the nine months ended September 30, 2025, the Company terminated its existing cross-currency swap agreements and entered into new cross-currency swap agreements for the same purpose and with substantially similar terms as the previous swaps. The new $1,250 million swaps expire in February 2029 at the time of the senior secured notes to which they are related, and the Company will receive semiannual interest payments on February 1 and August 1 from the counterparties based on a fixed interest rate until maturity of these agreements. The new $1,485 million swaps expire in January 2031 at the time of the term loans to which they are related, and the Company will receive quarterly interest payments from the counterparties based on a fixed interest rate until maturity of these agreements. The notional amount of the $1,485 million swaps will decrease over time in connection with the related term loans. The Company designated these new swap agreements as a hedge of its net investment in certain foreign subsidiaries.

As of September 30, 2025, the Company's cross-currency swaps were designated as a hedge of its net investment in certain foreign subsidiaries. For the three and nine months ended September 30, 2025, the Company recorded a $21 million gain and $(379) million loss, respectively, within AOCI as a result of these cross-currency swaps. For the three and nine months ended September 30, 2024, the Company recorded a $(101) million loss and $6 million gain, respectively, within AOCI as a result of these cross-currency swaps. For the three and nine months ended September 30, 2025 and 2024, the Company recognized approximately $11 million and $8 million, and $34 million and $26 million, respectively, related to the excluded component as a reduction of interest expense.

As of September 30, 2025, the portion of the Company's foreign currency denominated debt balance (net of original issue discount) designated as a hedge of its net investment in certain foreign subsidiaries totaled €2,922 million ($3,430 million). The amount of foreign exchange losses related to the net investment hedge included in the cumulative translation adjustment component of AOCI for the three and nine months ended September 30, 2025 and 2024 was $(3) million and $(114) million, and $(393) million and $(26) million, respectively.

6. Fair Value Measurements

The Company records certain assets and liabilities at fair value. Fair value is defined as the price that would be received to sell an asset or paid to transfer a liability in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants at the measurement date. A three-level fair value hierarchy that prioritizes the inputs used to measure fair value is described below. This hierarchy requires entities to maximize the use of observable inputs and minimize the use of unobservable inputs. The three levels of inputs used to measure fair value are as follows:

•Level 1 — Quoted prices in active markets for identical assets or liabilities.

•Level 2 — Observable inputs other than quoted prices included in Level 1, such as quoted prices for similar assets and liabilities in active markets; quoted prices for identical or similar assets and liabilities in markets that are not active; or other inputs that are observable or can be corroborated by observable market data.

•Level 3 — Unobservable inputs that are supported by little or no market activity. This includes certain pricing models, discounted cash flow methodologies and similar techniques that use significant unobservable inputs.

The carrying values of cash, cash equivalents, accounts receivable and accounts payable approximated their fair values as of September 30, 2025 and December 31, 2024 due to their short-term nature. As of September 30, 2025 and December 31, 2024, the fair value of total debt was $15,125 million and $13,966 million, respectively, as determined under Level 2 measurements for these financial instruments.

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Recurring Fair Value Measurements

The following table summarizes the fair value of the Company’s financial assets and liabilities that are measured and reported at fair value on a recurring basis as of September 30, 2025:

(in millions)						Level 1						Level 2						Level 3						Total
Assets:
Marketable securities						$	190					$	—					$	—					$	190
Derivatives						—						5						—						5
Total						$	190					$	5					$	—					$	195
Liabilities:
Derivatives						$	—					$	391					$	—					$	391
Contingent consideration						—						—						117						117
Total						$	—					$	391					$	117					$	508

The following table summarizes the fair value of the Company’s financial assets and liabilities that are measured and reported at fair value on a recurring basis as of December 31, 2024:

(in millions)						Level 1						Level 2						Level 3						Total
Assets:
Marketable securities						$	170					$	—					$	—					$	170
Derivatives						—						39						—						39
Total						$	170					$	39					$	—					$	209
Liabilities:
Derivatives						$	—					$	7					$	—					$	7
Contingent consideration						—						—						102						102
Total						$	—					$	7					$	102					$	109

Below is a summary of the valuation techniques used in determining fair value:

Marketable securities — The Company values trading and available-for-sale securities using the quoted market value of the securities held.

Derivatives — Derivatives consist of foreign exchange contracts, interest rate swaps, and cross-currency swaps. The fair value of foreign exchange contracts is based on observable market inputs of spot and forward rates or using other observable inputs. The fair value of the interest rate swaps is the estimated amount that the Company would receive or pay to terminate such agreements, taking into account market interest rates and the remaining time to maturities or using market inputs with mid-market pricing as a practical expedient for bid-ask spread. The fair value of the cross-currency swaps is the estimated amount that the Company would receive or pay to terminate such agreements, taking into account the effective interest rates, foreign exchange rates and the remaining time to maturities.

Contingent consideration — The Company values contingent consideration related to business combinations using a weighted probability calculation of potential payment scenarios discounted at rates reflective of the risks associated with the expected future cash flows. Assumptions used to estimate the fair value of contingent consideration include various financial metrics (revenues performance targets and operating forecasts) and the probability of achieving the specific targets. Based on the assessments of the probability of achieving specific targets, as of September 30, 2025 the Company has accrued approximately 69% of the maximum contingent consideration payments that could potentially become payable.

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The following table summarizes the changes in Level 3 financial assets and liabilities measured on a recurring basis for the nine months ended September 30, 2025:

(in millions)						Contingent Consideration
Balance as of December 31, 2024						$	102
Business combinations						51
Contingent consideration paid						(20)
Revaluations included in earnings and foreign currency translation adjustments						(16)
Balance as of September 30, 2025						$	117

The current portion of contingent consideration is included within accrued expenses and the long-term portion is included within other liabilities on the accompanying condensed consolidated balance sheets. Revaluations of contingent consideration are recognized in other (income) expense, net on the accompanying condensed consolidated statements of income. A change in significant unobservable inputs could result in a higher or lower fair value measurement of contingent consideration.

Non-recurring Fair Value Measurements

As of September 30, 2025, assets carried on the balance sheet and not remeasured to fair value on a recurring basis totaled $21,028 million and were identified as Level 3. These assets are comprised of debt investments and cost and equity method investments of $373 million, goodwill of $15,948 million and other identifiable intangibles, net of $4,707 million.

7. Credit Arrangements

The following is a summary of the Company’s revolving credit facilities as of September 30, 2025:

Facility						Interest Rates
$2,000 million (revolving credit facility)						U.S. Dollar Term SOFR plus a margin of 1.25% plus a 10 basis credit spread adjustment as of September 30, 2025
$110 million (receivables financing facility)						U.S. Dollar Term SOFR plus a margin of 1.00% plus a 10 basis credit spread adjustment as of September 30, 2025

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The following table summarizes the Company’s debt at the dates indicated:

(dollars in millions)						September 30, 2025						December 31, 2024
Revolving Credit Facility due 2026:
U.S. Dollar denominated borrowings—U.S. Dollar Term SOFR at average floating rates of —%						$	—					$	825
Senior Secured Credit Facilities:
Term A Loan due 2026—U.S. Dollar Term SOFR at floating rates of 5.51%						1,143						1,197
Term A Loan due 2026—Euribor at floating rates of 3.25%						293						272
Term A Loan due 2027—U.S. Dollar Term SOFR at floating rates of 5.55%						1,047						1,094
Term B Loan due 2025—Euribor at floating rates of —%						—						542
Term B Loan due 2031—U.S. Dollar Term SOFR at floating rates of —%						—						1,485
Term B Loan due 2031—U.S. Dollar Term SOFR at floating rates of 5.75%						1,970						—
5.700% Senior Secured Notes due 2028—U.S. Dollar denominated						750						750
6.250% Senior Secured Notes due 2029—U.S. Dollar denominated						1,250						1,250
5.0% Senior Notes due 2027—U.S. Dollar denominated						1,100						1,100
5.0% Senior Notes due 2026—U.S. Dollar denominated						1,050						1,050
6.500% Senior Notes due 2030—U.S. Dollar denominated						500						500
6.250% Senior Notes due 2032—U.S. Dollar denominated						2,000						—
2.875% Senior Notes due 2025—Euro denominated						—						436
2.25% Senior Notes due 2028—Euro denominated						845						748
2.875% Senior Notes due 2028—Euro denominated						834						739
1.750% Senior Notes due 2026—Euro denominated						646						572
2.250% Senior Notes due 2029—Euro denominated						1,056						935
Receivables financing facility due 2027—U.S. Dollar Term SOFR at floating rates of 5.30%:
Revolving Loan Commitment						110						110
Term Loan						440						440
Principal amount of debt						15,034						14,045
Less: unamortized discount and debt issuance costs						(77)						(62)
Less: current portion						(2,164)						(1,145)
Long-term debt						$	12,793					$	12,838

Contractual maturities of long-term debt as of September 30, 2025 are as follows:

(in millions)
Remainder of 2025						$	43
2026						3,191
2027						2,639
2028						2,449
2029						2,326
Thereafter						4,386
						$	15,034

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Senior Secured Credit Facilities

On March 10, 2025, the Company entered into an Amendment (the “Amendment”) to its Fifth Amended and Restated Credit Agreement among IQVIA Inc., a wholly owned subsidiary of the Company, the Company, IQVIA RDS Inc., a wholly owned subsidiary of the Company, the other guarantors party thereto, Bank of America, N.A., as administrative agent and as collateral agent, and the Lenders (as defined therein) party thereto. The Amendment, among other changes, established a new incremental Term B-5 dollar loan facility in an aggregate principal amount equal to $1,985 million (the “Incremental Term B-5 Dollar Facility”). Proceeds of the Incremental Term B-5 Dollar Facility were applied to (a) refinance the existing Term B-4 dollar loans and (b) repay in full the existing Term B-2 Euro loans. The interest rates for borrowings under the Incremental Term B-5 Dollar Facility are based on the Secured Overnight Financing Rate plus an applicable margin of 1.75% per annum. In connection with this Amendment, we recognized a $4 million loss on extinguishment of debt, which includes fees and related expenses.

As of September 30, 2025, the Company’s Fifth Amended and Restated Credit Agreement provided financing through several senior secured credit facilities of up to $6,448 million, which consisted of $4,453 million principal amounts of debt outstanding (as detailed in the table above), and $1,995 million of available borrowing capacity on the $2,000 million revolving credit facility and standby letters of credit. The revolving credit facility is comprised of a $1,175 million senior secured revolving facility available in U.S. dollars, a $600 million senior secured revolving facility available in U.S. dollars, Euros, Swiss Francs and other foreign currencies, and a $225 million senior secured revolving facility available in U.S. dollars and Yen.

Senior Notes

During the three months ended September 30, 2025, the Company's Euro denominated 2.875% Senior Notes due 2025 matured and were repaid.

On June 4, 2025, IQVIA Inc. (the “Issuer”), a wholly owned subsidiary of the Company, completed the issuance and sale of $2,000 million in gross proceeds of 6.250% senior notes due 2032 (the “Senior Notes”). The Senior Notes were issued pursuant to an Indenture, dated June 4, 2025, among the Issuer, U.S. Bank Trust Company, National Association, as trustee of the Senior Notes, and certain subsidiaries of the Issuer as guarantors. The net proceeds from the notes offering were used to repay existing borrowings under the Company’s revolving credit facility and to pay fees and expenses related to the Senior Notes offering, with any excess proceeds used for general corporate purposes.

The Senior Notes are unsecured obligations of the Company, will mature on June 1, 2032, unless earlier repurchased or redeemed in accordance with their terms, and bear interest at the rate of 6.250% per year, with interest payable semi-annually on June 1 and December 1 of each year, beginning on December 1, 2025.

The Company may redeem the Senior Notes prior to their final stated maturity, subject to a customary make-whole premium, at any time prior to June 1, 2028 (subject to a customary “equity claw” redemption right) and thereafter subject to a redemption premium declining from 3.125% to 0.000%.

Restrictive Covenants

The Company’s debt agreements provide for certain covenants and events of default customary for similar instruments, including a covenant not to exceed a specified ratio of consolidated senior secured net indebtedness to Consolidated EBITDA, as defined in the senior secured credit facility agreement and a covenant to maintain a specified minimum interest coverage ratio. If an event of default occurs under any of the Company’s or the Company’s subsidiaries’ financing arrangements, the creditors under such financing arrangements will be entitled to take various actions, including the acceleration of amounts due under such arrangements, and in the case of the lenders under the revolving credit facility and term loans, other actions permitted to be taken by a secured creditor. The Company’s long-term debt arrangements contain other usual and customary restrictive covenants that, among other things, place limitations on the Company’s ability to declare dividends. As of September 30, 2025, the Company was in compliance in all material respects with the financial covenants under the Company’s financing arrangements.

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8. Contingencies

The Company and its subsidiaries are involved in legal and tax proceedings, claims and litigation arising in the ordinary course of business. Management periodically assesses the Company’s liabilities and contingencies in connection with these matters based upon the latest information available. For those matters where management currently believes it is probable that the Company will incur a loss and that the probable loss or range of loss can be reasonably estimated, the Company has recorded an accrual in the consolidated financial statements based on its best estimates of such loss. In other instances, because of the uncertainties related to either the probable outcome or the amount or range of loss, management is unable to make a reasonable estimate of a liability, if any.

However, even in many instances where the Company has recorded an estimated liability, the Company is unable to predict with certainty the final outcome of the matter or whether resolution of the matter will materially affect the Company’s results of operations, financial position or cash flows. As additional information becomes available, the Company adjusts its assessments and estimates of such liabilities accordingly.

The Company routinely enters into agreements with third parties, including its clients and suppliers, all in the normal course of business. In these agreements, the Company sometimes agrees to indemnify and hold harmless the other party for any damages such other party may suffer as a result of potential intellectual property infringement and other claims. The Company has not accrued a liability with respect to these matters generally, as the exposure is considered remote.

Based on its review of the latest information available, management does not expect the impact of pending legal and tax proceedings, claims and litigation, either individually or in the aggregate, to have a material adverse effect on the Company’s results of operations, cash flows or financial position. However, one or more unfavorable outcomes in any claim or litigation against the Company could have a material adverse effect for the period in which it is resolved. The following is a summary of certain legal matters involving the Company.

On January 10, 2017, Quintiles IMS Health Incorporated and IMS Software Services Ltd. (collectively “IQVIA Parties”), filed a lawsuit in the U.S. District Court for the District of New Jersey against Veeva Systems, Inc. (“Veeva”) alleging Veeva unlawfully used IQVIA Parties intellectual property to improve Veeva data offerings, to promote and market Veeva data offerings and to improve Veeva technology offerings. IQVIA Parties sought injunctive relief, appointment of a monitor, the award of compensatory and punitive damages and reimbursement of all litigation expenses, including reasonable attorneys’ fees and costs. On March 13, 2017, Veeva filed counterclaims alleging anticompetitive business practices in violation of the Sherman Act and state laws. Veeva claimed damages in excess of $200 million, and sought punitive damages and litigation costs, including attorneys’ fees. The Company believed the counterclaims were without merit, rejected all counterclaims raised by Veeva and vigorously defended IQVIA Parties’ position and pursued its claims against Veeva. Since the initial filings, the parties filed additional litigations against each other, primarily concerning the use of IQVIA data with various other Veeva products.

On May 7, 2021, the Court issued an order and opinion (the “Order”) in which it found significant evidence that Veeva had (1) misappropriated IQVIA data and unlawfully used it to improve Veeva data offerings, (2) engaged in a cover-up by deleting significant evidence of its theft of IQVIA’s trade secrets, and (3) improperly withheld certain evidence under privilege in furtherance of a crime and/or fraud against IQVIA. The Court imposed five sanctions against Veeva, including ordering three separate adverse inference instructions be issued to the jury and that IQVIA be permitted to present evidence to the jury of Veeva’s destruction efforts. Veeva appealed the Order. On March 30, 2024, the Court denied Veeva’s appeal with regard to its rejected privilege claims, while reserving ruling on the appropriate sanctions to be imposed for a later time.

In August 2025, the parties reached complete resolution of all pending legal disputes. Neither party made a payment to the other party in connection with the resolution of these legal disputes.

9. Stockholders’ Equity

Preferred Stock

The Company is authorized to issue 1.0 million shares of preferred stock, $0.01 per share par value. No shares of preferred stock were issued or outstanding as of September 30, 2025 or December 31, 2024.

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Equity Repurchase Program

On February 5, 2025, the Company's Board of Directors increased the stock repurchase authorization under the Company's equity repurchase program (the "Repurchase Program") with respect to the repurchase of the Company's common stock by an additional $2,000 million, which increased the total amount that has been authorized under the Repurchase Program to $13,725 million. The Repurchase Program does not obligate the Company to repurchase any particular amount of common stock, and it may be modified, extended, suspended or discontinued at any time.

During the nine months ended September 30, 2025, the Company repurchased 6.4 million shares of its common stock for $1,032 million under the Repurchase Program. As of September 30, 2025, the Company had remaining authorization to repurchase up to $1,981 million of its common stock under the Repurchase Program. In addition, from time to time, the Company has repurchased and may continue to repurchase common stock through private or other transactions outside of the Repurchase Program.

10. Business Combinations

The Company completed individually and in the aggregate immaterial acquisitions during the nine months ended September 30, 2025. The Company’s assessment of fair value, including the valuation of certain identified intangibles and noncontrolling interests ("NCI"), and the purchase price allocation related to these acquisitions is preliminary and subject to change upon completion. Further adjustments, largely related to acquired intangible assets and related deferred taxes, may be necessary as additional information related to the fair values of assets acquired and liabilities assumed is assessed during the measurement period (up to one year from the acquisition date). The Company recorded goodwill from these acquisitions, primarily attributable to assembled workforce, expected synergies and new customer relationships. The fair value of the NCI as of the acquisition date was based on fair value assessments, primarily using an income approach and applying the NCI’s ownership percentage. The condensed consolidated financial statements include the results of the acquisitions subsequent to their respective closing dates. Pro forma information is not presented as pro forma results of operations would not be materially different to the actual results of operations of the Company.

The following table provides certain preliminary financial information for these acquisitions:

(in millions)						September 30, 2025
Assets acquired:
Cash and cash equivalents						$	76
Accounts receivable						98
Other assets						33
Goodwill						596
Other identifiable intangibles						378
Liabilities assumed:
Other liabilities						(74)
Deferred income taxes, long-term						(34)
Net assets acquired (1)						$	1,073
Fair value of noncontrolling interests(2)						127
Fair value of controlling interests acquired						$	946

(1) Net assets acquired includes contingent consideration and deferred purchase price of $56 million, and $143 million related to NCI and the net assets of the step acquisition disclosed in (2) below.

(2) Includes $8 million related to a step acquisition through which the Company gained a controlling interest in, and therefore consolidated, an entity in which it previously held an investment in an unconsolidated affiliate.

The portion of goodwill deductible for income tax purposes was preliminarily assessed as $335 million.

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The following table provides a summary of the preliminary estimated fair value of certain intangible assets acquired:

(in millions)						Amortization Period															September 30, 2025
Other identifiable intangibles:
Customer relationships						9			-			17			years						$	334
Backlog						1			-			2			years						29
Databases												2			years						6
Software and related assets						2			-			3			years						4
Trade names						3			-			5			years						3
Non-compete agreements						2			-			5			years						2
Total Other identifiable intangibles																					$	378

11. Restructuring

The Company has continued to take restructuring actions in 2025 to align its resources and reduce overcapacity to adapt to changing market conditions and integrate acquisitions. These actions include consolidating functional activities, eliminating redundant positions, and aligning resources with customer requirements. These restructuring actions are expected to continue throughout 2025 and into 2026.

The following amounts were recorded for the restructuring plans:

(in millions)						Severance and Related Costs
Balance as of December 31, 2024						$	21
Expense, net of reversals						81
Payments						(71)
Foreign currency translation and other						2
Balance as of September 30, 2025						$	33

The reversals were due to changes in estimates primarily resulting from the redeployment of staff and higher than expected voluntary terminations. Restructuring costs are not allocated to the Company’s reportable segments as they are not part of the segment performance measures regularly reviewed by management. The Company expects that the majority of the restructuring accruals as of September 30, 2025 will be paid in 2025 and 2026.

12. Income Taxes

The Company's effective income tax rate was 18.6% and 18.6% in the third quarter of 2025 and 2024, respectively. The Company's effective income tax rate was 18.3% and 16.8% in the first nine months of 2025 and 2024, respectively. The effective income tax rate in the third quarter and in the first nine months of 2025 and 2024 was favorably impacted due to changes in the geographical mix of earnings amongst the United States and foreign tax jurisdictions. The effective income tax rate in the third quarter and in the first nine months of 2024 was also favorably impacted by $2 million and $14 million, respectively, as a result of excess tax benefits recognized upon settlement of share-based compensation awards. The effective income tax rate in the third quarter and in the first nine months of 2025 was unfavorably impacted by $0 million and $3 million, respectively, of tax expense recognized upon settlement of share-based compensation awards.

On July 4, 2025, the U.S. government enacted the One Big Beautiful Bill Act ("OBBBA"), which includes several changes to U.S. federal income tax law, including the temporary and permanent extension, of expiring provisions of the Tax Cuts and Jobs Act of 2017. The impacts of the OBBBA are not expected to be material to the 2025 consolidated financial statements, however the Company will continue to evaluate impacts to future periods.

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On December 12, 2022, the European Union member states agreed to implement the Organization for Economic Cooperation and Development’s (“OECD”) Pillar Two global corporate minimum tax rate of 15% on companies with revenues of at least €750 million, which went into effect in 2024. The Company has continued to evaluate the effect of this through the third quarter of 2025 and determined that it did not have any material impacts for the current year. The Company will continue to assess the impact of this proposal as countries are actively considering changes to their tax laws to adopt certain parts of the OECD's proposal.

13. Accumulated Other Comprehensive (Loss) Income

Below is a summary of the components of AOCI:

(in millions)						Foreign Currency Translation						Derivative Instruments						Defined Benefit Plans						Income Taxes						Total
Balance as of December 31, 2024						$	(1,092)					$	(5)					$	15					$	44					$	(1,038)
Other comprehensive income (loss) before reclassifications						—						(34)						(4)						152						114
Reclassification adjustments						—						(5)						—						1						(4)
Balance as of September 30, 2025						$	(1,092)					$	(44)					$	11					$	197					$	(928)

Below is a summary of the adjustments for amounts reclassified from AOCI into the condensed consolidated statements of income and the affected financial statement line item:

(in millions)						Affected Financial Statement Line Item						Three Months Ended September 30,												Nine Months Ended September 30,
												2025						2024						2025						2024
Derivative instruments:
Interest rate swaps						Interest expense						$	2					$	8					$	4					$	38
Foreign exchange forward contracts						Revenues						1						3						1						—
Total before income taxes												3						11						5						38
Income taxes												—						3						1						10
Total net of income taxes												$	3					$	8					$	4					$	28

14. Segments

The following table presents the Company’s operations by reportable segment. The Company is managed through three reportable segments, Technology & Analytics Solutions, Research & Development Solutions and Contract Sales & Medical Solutions. Technology & Analytics Solutions provides mission critical information, technology solutions and real world insights and services to the Company’s life science clients. Research & Development Solutions, which primarily serves biopharmaceutical customers, provides outsourced clinical research and clinical trial related services. Contract Sales & Medical Solutions provides health care provider (including contract sales) and patient engagement services to both biopharmaceutical customers and the broader healthcare market.

Certain costs are not allocated to the Company's segments and are reported as general corporate and unallocated expenses. These costs primarily consist of stock-based compensation, expenses related to integration activities and acquisitions, as well as certain general corporate and unallocated expenses. The Company also does not allocate restructuring costs, depreciation and amortization or impairment charges, if any, to its segments. Asset information by segment is not presented, as this measure is not used by the chief executive officer, who is the chief operating decision maker ("CODM"), to assess the Company’s performance.

For all segments, the CODM uses segment revenue and segment profit in the annual budgeting and forecasting process. The CODM considers budget-to-actual variances on a monthly and quarterly basis for both segment revenue and profit when making decisions about allocating operating and capital resources to the segments. The CODM also uses segment revenue and profit to assess the performance for each segment by comparing the results of each segment with one another and in determining the compensation of certain employees.

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The Company’s reportable segment information is presented below:

						Three Months Ended September 30,												Nine Months Ended September 30,
(in millions)						2025						2024						2025						2024
Revenues
Technology & Analytics Solutions						$	1,631					$	1,554					$	4,805					$	4,502
Research & Development Solutions						2,260						2,162						6,563						6,404
Contract Sales & Medical Solutions						209						180						578						541
Total revenues						4,100						3,896						11,946						11,447
Cost of revenues, exclusive of depreciation and amortization
Technology & Analytics Solutions						1,014						922						2,972						2,720
Research & Development Solutions						1,532						1,442						4,481						4,268
Contract Sales & Medical Solutions						181						154						499						462
Total cost of revenues, exclusive of depreciation and amortization						2,727						2,518						7,952						7,450
Selling, general and administrative expenses
Technology & Analytics Solutions						247						227						714						681
Research & Development Solutions						232						222						675						666
Contract Sales & Medical Solutions						15						14						43						45
Total selling, general and administrative expenses reportable segments						494						463						1,432						1,392
Segment profit
Technology & Analytics Solutions						370						405						1,119						1,101
Research & Development Solutions						496						498						1,407						1,470
Contract Sales & Medical Solutions						13						12						36						34
Total segment profit						879						915						2,562						2,605
General corporate and unallocated expenses						(20)						(59)						(99)						(147)
Depreciation and amortization						(286)						(278)						(827)						(811)
Restructuring costs						(20)						(28)						(81)						(71)
Total income from operations						553						550						1,555						1,576
Interest income						(13)						(13)						(34)						(36)
Interest expense						189						170						536						499
Loss on extinguishment of debt						—						—						4						—
Other (income) expense, net						(31)						44						(5)						(12)
Income before income taxes and equity in earnings (losses) of unconsolidated affiliates						$	408					$	349					$	1,054					$	1,125

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15. Earnings Per Share

The following table presents the computation of basic and diluted earnings per share:

						Three Months Ended September 30,												Nine Months Ended September 30,
(in millions, except per share data)						2025						2024						2025						2024
Numerator:
Net income attributable to IQVIA Holdings Inc.						$	331					$	285					$	846					$	936
Denominator:
Basic weighted average common shares outstanding						170.2						182.1						172.6						182.1
Effect of dilutive stock options and share awards						1.5						2.1						1.5						2.2
Diluted weighted average common shares outstanding						171.7						184.2						174.1						184.3
Earnings per share attributable to common stockholders:
Basic						$	1.94					$	1.57					$	4.90					$	5.14
Diluted						$	1.93					$	1.55					$	4.86					$	5.08

Stock-based awards will have a dilutive effect under the treasury method when the respective period's average market value of the Company's common stock exceeds the exercise proceeds. Performance awards are included in diluted earnings per share based on if the performance targets have been met at the end of the reporting period.

For the three and nine months ended September 30, 2025 and 2024, the weighted average number of outstanding stock-based awards not included in the computation of diluted earnings per share because they are subject to performance conditions that have not been met at the end of the reporting period or the effect of including such stock-based awards in the computation would be anti-dilutive was 1.8 million and 1.0 million, and 2.5 million and 1.0 million, respectively.

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Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations

Cautionary Statement for Forward-Looking Information

You should read the following discussion and analysis of our financial condition and results of operations together with our condensed consolidated financial statements and the related notes included elsewhere in this Quarterly Report on Form 10-Q and with our audited consolidated financial statements and the notes thereto included in our Annual Report on Form 10-K for the fiscal year ended December 31, 2024 (our “2024 Form 10-K”).

In addition to historical condensed consolidated financial information, the following discussion contains or incorporates by reference forward-looking statements within the meaning of the federal securities laws, including Section 27A of the Securities Act of 1933, as amended (“Securities Act”), and Section 21E of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), that are not historical facts but reflect, among other things, our current expectations, our forecasts and our anticipated results of operations, all of which are subject to known and unknown risks, uncertainties and other factors that may cause our actual results, performance or achievements, market trends, or industry results to differ materially from those expressed or implied by such forward-looking statements. Therefore, any statements contained herein that are not statements of historical fact may be forward-looking statements and should be evaluated as such. Without limiting the foregoing, the words “assumes,” “anticipates,” “believes,” “estimates,” “expects,” “intends,” “may,” "forecasts," “plans,” “projects,” “should,” “seeks,” “sees,” “targets,” “will,” “would” and similar words and expressions, and variations and negatives of these words are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. We assume no obligation to update any such forward-looking information to reflect actual results or changes in our outlook or the factors affecting such forward-looking information.

We caution you that any such forward-looking statements are further qualified by important factors that could cause our actual operating results to differ materially from those in the forward-looking statements, including without limitation, business disruptions caused by natural disasters, pandemics such as the COVID-19 (coronavirus) outbreak, including any variants, and the public health policy responses to the outbreak, and international conflicts or other disruptions outside of our control; most of our contracts may be terminated on short notice, and we may lose or experience delays with large client contracts or be unable to enter into new contracts; the market for our services may not grow as we expect; we may be unable to successfully develop and market new services or enter new markets; imposition of restrictions on our use of data by data suppliers or their refusal to license data to us; any failure by us to comply with contractual, regulatory or ethical requirements under our contracts, including current or future changes to data protection and privacy laws; breaches or misuse of our or our outsourcing partners’ security or communications systems; failure to meet our productivity or business transformation objectives; failure to successfully invest in growth opportunities; our ability to protect our intellectual property rights and our susceptibility to claims by others that we are infringing on their intellectual property rights; the expiration or inability to acquire third party licenses for technology or intellectual property; any failure by us to accurately and timely price and formulate cost estimates for contracts, or to document change orders; hardware and software failures, delays in the operation of our computer and communications systems or the failure to implement system enhancements; the rate at which our backlog converts to revenues; our ability to acquire, develop and implement technology necessary for our business; consolidation in the industries in which our clients operate; risks related to client or therapeutic concentration; government regulators or our customers may limit the number or scope of indications for medicines and treatments or withdraw products from the market, and government regulators may impose new regulatory requirements or may adopt new regulations affecting the biopharmaceutical industry; the risks associated with operating on a global basis, including currency or exchange rate fluctuations and legal compliance, including anti-corruption laws; risks related to the enactment of legislation or the imposition of regulations or other restrictions or actions by governments that create business uncertainty and have the potential to limit trade; risks related to changes in accounting standards; general economic conditions in the markets in which we operate, including financial market conditions, inflation and risks related to sales to government entities; the impact of changes in tax laws and regulations; and our ability to successfully integrate, and achieve expected benefits from, our acquired businesses. For a further discussion of the risks relating to our business, see Part I—Item 1A—“Risk Factors” in our 2024 Form 10-K, as updated in our subsequently filed Quarterly Reports on Form 10-Q.

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Overview

IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. IQVIA’s portfolio of solutions are powered by IQVIA Connected Intelligence™ to deliver actionable insights and services built on high-quality health data, Healthcare-grade AI®, advanced analytics, the latest technologies and extensive domain expertise. We are committed to using artificial intelligence ("AI") responsibly, with AI-powered capabilities built on best-in-class approaches to privacy, regulatory compliance and patient safety, and delivering AI to the high standards of trust, scalability and precision demanded by the industry. With approximately 91,000 employees in over 100 countries, including experts in healthcare, life sciences, data science, technology and operational excellence, we are dedicated to accelerating the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide.

We are a global leader in protecting individual patient privacy. We use a wide variety of privacy-enhancing technologies and safeguards to protect individual privacy while generating and analyzing information on a scale that helps healthcare stakeholders identify disease patterns and correlate with the precise treatment path and therapy needed for better outcomes. Our insights and execution capabilities help biotech, medical device and pharmaceutical companies, medical researchers, government agencies, payers and other healthcare stakeholders tap into a deeper understanding of diseases, human behaviors and scientific advances, in an effort to advance their path toward cures.

We are managed through three reportable segments: Technology & Analytics Solutions, Research & Development Solutions and Contract Sales & Medical Solutions. Technology & Analytics Solutions provides mission critical information, technology solutions and real world insights and services to our life science clients. Research & Development Solutions, which primarily serves biopharmaceutical customers, provides outsourced clinical research and clinical trial related services. Contract Sales & Medical Solutions provides health care provider (including contract sales) and patient engagement services to both biopharmaceutical clients and the broader healthcare market.

Sources of Revenue

Total revenues are comprised of revenues from the provision of our services. We do not have any material product revenues.

Costs and Expenses

Our costs and expenses are comprised primarily of our cost of revenues including reimbursed expenses and selling, general and administrative expenses. Cost of revenues includes compensation and benefits for billable employees and personnel involved in production, trial monitoring, data management and delivery, and the costs of acquiring and processing data for our information offerings; costs of staff directly involved with delivering technology-related services offerings and engagements, related accommodations and the costs of data purchased specifically for technology services engagements; and other expenses directly related to service contracts such as courier fees, laboratory supplies, professional services and travel expenses. Reimbursed expenses, which are included in cost of revenues, are comprised principally of payments to investigators who oversee clinical trials and travel expenses for our clinical monitors and sales representatives. Selling, general and administrative expenses include costs related to sales, marketing and administrative functions (including human resources, legal, finance, quality assurance, compliance and general management) for compensation and benefits, travel, professional services, training and expenses for information technology and facilities. We also incur costs and expenses associated with depreciation and amortization.

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Foreign Currency Translation

In the first nine months of 2025, approximately 30% of our revenues were denominated in currencies other than the United States dollar, which represents approximately 60 currencies. Because a large portion of our revenues and expenses are denominated in foreign currencies and our financial statements are reported in United States dollars, changes in foreign currency exchange rates can significantly affect our results of operations. The revenues and expenses of our foreign operations are generally denominated in local currencies and translated into United States dollars for financial reporting purposes. Accordingly, exchange rate fluctuations will affect the translation of foreign results into United States dollars for purposes of reporting our condensed consolidated results. As a result, we believe that reporting results of operations that exclude the effects of foreign currency rate fluctuations on certain financial results can facilitate analysis of period to period comparisons. This constant currency information assumes the same foreign currency exchange rates that were in effect for the comparable prior-year period were used in translation of the current period results. As such, the differences noted below between reported results of operations and constant currency information are wholly attributable to the effects of foreign currency rate fluctuations.

Consolidated Results of Operations

For information regarding our results of operations for Technology & Analytics Solutions, Research & Development Solutions and Contract Sales & Medical Solutions, refer to “Segment Results of Operations” later in this section.

Revenues

						Three Months Ended September 30,												Change
(in millions)						2025						2024						$						%
Revenues						$	4,100					$	3,896					$	204					5.2		%

For the third quarter of 2025, our revenues increased $204 million, or 5.2%, as compared to the same period in 2024. This increase was comprised of constant currency revenue growth of approximately $150 million, or 3.9%, reflecting a $52 million increase in Technology & Analytics Solutions, a $73 million increase in Research & Development Solutions, and a $25 million increase in Contract Sales & Medical Solutions.

						Nine Months Ended September 30,												Change
(in millions)						2025						2024						$						%
Revenues						$	11,946					$	11,447					$	499					4.4		%

For the first nine months of 2025, our revenues increased $499 million, or 4.4%, as compared to the same period in 2024. This increase was comprised of constant currency revenue growth of approximately $418 million, or 3.7%, reflecting a $263 million increase in Technology & Analytics Solutions, a $123 million increase in Research & Development Solutions, and a $32 million increase in Contract Sales & Medical Solutions.

Cost of Revenues, exclusive of Depreciation and Amortization

						Three Months Ended September 30,												Nine Months Ended September 30,
(in millions)						2025						2024						2025						2024
Cost of revenues, exclusive of depreciation and amortization						$	2,727					$	2,518					$	7,952					$	7,450
% of revenues						66.5		%				64.6		%				66.6		%				65.1		%

The $209 million increase in cost of revenues, exclusive of depreciation and amortization, for the three months ended September 30, 2025 as compared to the same period in 2024 included a constant currency increase of approximately $183 million, or 7.3%, reflecting a $77 million increase in Technology & Analytics Solutions, an $82 million increase in Research & Development Solutions, and a $24 million increase in Contract Sales & Medical Solutions.

The $502 million increase in cost of revenues, exclusive of depreciation and amortization, for the nine months ended September 30, 2025 as compared to the same period in 2024 included a constant currency increase of approximately $491 million, or 6.6%, reflecting a $236 million increase in Technology & Analytics Solutions, a $223 million increase in Research & Development Solutions, and a $32 million increase in Contract Sales & Medical Solutions.

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Selling, General and Administrative Expenses

						Three Months Ended September 30,												Nine Months Ended September 30,
(in millions)						2025						2024						2025						2024
Selling, general and administrative expenses						$	514					$	522					$	1,531					$	1,539
% of revenues						12.5		%				13.4		%				12.8		%				13.4		%

The $8 million decrease in selling, general and administrative expenses for the three months ended September 30, 2025 as compared to the same period in 2024 included a constant currency decrease of approximately $14 million, or 2.7%, reflecting a $14 million increase in Technology & Analytics Solutions, a $9 million increase in Research & Development Solutions, a $1 million increase in Contract Sales & Medical Solutions, and a $38 million decrease in general corporate and unallocated expenses.

The $8 million decrease in selling, general and administrative expenses for the nine months ended September 30, 2025 as compared to the same period in 2024 included a constant currency decrease of approximately $13 million, or 0.8%, reflecting a $27 million increase in Technology & Analytics Solutions, a $10 million increase in Research & Development Solutions, a $1 million decrease in Contract Sales & Medical Solutions, and a $49 million decrease in general corporate and unallocated expenses.

Depreciation and Amortization

						Three Months Ended September 30,												Nine Months Ended September 30,
(in millions)						2025						2024						2025						2024
Depreciation and amortization						$	286					$	278					$	827					$	811
% of revenues						7.0		%				7.1		%				6.9		%				7.1		%

The $8 million and $16 million increases in depreciation and amortization for the three and nine months ended September 30, 2025 compared to the same periods in 2024 are mainly related to an increase in amortization of capitalized software costs.

Restructuring Costs

						Three Months Ended September 30,												Nine Months Ended September 30,
(in millions)						2025						2024						2025						2024
Restructuring costs						$	20					$	28					$	81					$	71

The restructuring costs incurred during 2025 and 2024 were due to ongoing efforts to streamline our global operations and reduce overcapacity to adapt to changing market conditions and integrate acquisitions. These restructuring actions are expected to occur throughout 2025 and into 2026 and are expected to consist of consolidating functional activities, eliminating redundant positions and aligning resources with customer requirements.

Interest Income and Interest Expense

						Three Months Ended September 30,												Nine Months Ended September 30,
(in millions)						2025						2024						2025						2024
Interest income						$	(13)					$	(13)					$	(34)					$	(36)
Interest expense						$	189					$	170					$	536					$	499

Interest income includes interest received primarily from bank balances and investments. Interest income during the three months ended September 30, 2025 remained consistent as compared to the same period in 2024, and for the nine months ended September 30, 2025 decreased compared to the same period in 2024 primarily as a result of lower interest rates.

Interest expense during the three and nine months ended September 30, 2025 increased compared to the same periods in 2024 as a result of higher outstanding debt balances.

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Other (Income) Expense, Net

						Three Months Ended September 30,												Nine Months Ended September 30,
(in millions)						2025						2024						2025						2024
Other (income) expense, net						$	(31)					$	44					$	(5)					$	(12)

Other (income) expense, net for the three months ended September 30, 2025 increased compared to the same period in 2024 primarily due to foreign currency gain on transactions.

Other (income) expense, net for the nine months ended September 30, 2025 decreased compared to the same period in 2024 primarily due to less revaluations of contingent consideration arrangements and adjustments in investment balances, offset by less foreign currency loss on transactions.

Income Tax Expense

						Three Months Ended September 30,												Nine Months Ended September 30,
(in millions)						2025						2024						2025						2024
Income tax expense						$	76					$	65					$	193					$	189

Our effective income tax rate was 18.6% and 18.6% in the third quarter of 2025 and 2024, respectively. Our effective income tax rate was 18.3% and 16.8% in the first nine months of 2025 and 2024, respectively. Our effective income tax rate in the third quarter and in the first nine months of 2025 and 2024 was favorably impacted due to changes in the geographical mix of earnings amongst the United States and foreign tax jurisdictions. Our effective income tax rate in the third quarter and in the first nine months of 2024 was also favorably impacted by $2 million and $14 million, respectively, as a result of excess tax benefits recognized upon settlement of share-based compensation awards. Our effective income tax rate in the third quarter and in the first nine months of 2025 was unfavorably impacted by $0 million and $3 million, respectively, of tax expense recognized upon settlement of share-based compensation awards.

On July 4, 2025, the U.S. government enacted the One Big Beautiful Bill Act ("OBBBA"), which includes several changes to U.S. federal income tax law, including the temporary and permanent extension, of expiring provisions of the Tax Cuts and Jobs Act of 2017. The impacts of the OBBBA are not expected to be material to the 2025 consolidated financial statements, however we will continue to evaluate impacts to future periods.

On December 12, 2022, the European Union member states agreed to implement the Organization for Economic Cooperation and Development’s (“OECD”) Pillar Two global corporate minimum tax rate of 15% on companies with revenues of at least €750 million, which went into effect in 2024. We have continued to evaluate the effect of this through the third quarter of 2025 and determined that it did not have any material impacts for the current year. We will continue to assess the impact of this proposal as countries are actively considering changes to their tax laws to adopt certain parts of the OECD's proposal.

Equity in Earnings (Losses) of Unconsolidated Affiliates

						Three Months Ended September 30,												Nine Months Ended September 30,
(in millions)						2025						2024						2025						2024
Equity in earnings (losses) of unconsolidated affiliates						$	—					$	1					$	(14)					$	—

Equity in earnings (losses) of unconsolidated affiliates for the three and nine months ended September 30, 2025, decreased compared to the same periods in 2024, due to the results in the operations of our unconsolidated affiliates.

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Segment Results of Operations

Revenues and profit by segment are as follows:

Three Months Ended September 30, 2025 and 2024
						Segment Revenues												Segment Profit
(in millions)						2025						2024						2025						2024
Technology & Analytics Solutions						$	1,631					$	1,554					$	370					$	405
Research & Development Solutions						2,260						2,162						496						498
Contract Sales & Medical Solutions						209						180						13						12
Total						4,100						3,896						879						915
General corporate and unallocated expenses																		(20)						(59)
Depreciation and amortization																		(286)						(278)
Restructuring costs																		(20)						(28)
Consolidated						$	4,100					$	3,896					$	553					$	550

Nine Months Ended September 30, 2025 and 2024
						Segment Revenues												Segment Profit
(in millions)						2025						2024						2025						2024
Technology & Analytics Solutions						$	4,805					$	4,502					$	1,119					$	1,101
Research & Development Solutions						6,563						6,404						1,407						1,470
Contract Sales & Medical Solutions						578						541						36						34
Total						11,946						11,447						2,562						2,605
General corporate and unallocated expenses																		(99)						(147)
Depreciation and amortization																		(827)						(811)
Restructuring costs																		(81)						(71)
Consolidated						$	11,946					$	11,447					$	1,555					$	1,576

Certain costs are not allocated to our segments and are reported as general corporate and unallocated expenses. These costs primarily consist of stock-based compensation, expenses related to integration activities and acquisitions, as well as certain general corporate and unallocated expenses. We also do not allocate restructuring costs, depreciation and amortization, or impairment charges, if any, to our segments.

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Technology & Analytics Solutions

						Three Months Ended September 30,												Change
(in millions)						2025						2024						$						%
Revenues						$	1,631					$	1,554					$	77					5.0		%
Cost of revenues, exclusive of depreciation and amortization						1,014						922						92						10.0
Selling, general and administrative expenses						247						227						20						8.8
Segment profit						$	370					$	405					$	(35)					(8.6)		%

						Nine Months Ended September 30,												Change
(in millions)						2025						2024						$						%
Revenues						$	4,805					$	4,502					$	303					6.7		%
Cost of revenues, exclusive of depreciation and amortization						2,972						2,720						252						9.3
Selling, general and administrative expenses						714						681						33						4.8
Segment profit						$	1,119					$	1,101					$	18					1.6		%

Revenues

Technology & Analytics Solutions’ revenues were $1,631 million for the third quarter of 2025, an increase of $77 million, or 5.0%, over the same period in 2024. This increase was comprised of constant currency revenue growth of approximately $52 million, or 3.3%, reflecting revenue growth primarily in the Americas region and to a lesser extent in the Asia-Pacific region.

Technology & Analytics Solutions’ revenues were $4,805 million for the first nine months of 2025, an increase of $303 million, or 6.7%, over the same period in 2024. This increase was comprised of constant currency revenue growth of approximately $263 million, or 5.8%, reflecting revenue growth primarily in the Americas region and to a lesser extent in the Europe and Africa region.

The constant currency revenue growth for the three and nine months ended September 30, 2025 was primarily driven by an increase in information and technology services and to a lesser extent by real world services.

Cost of Revenues, exclusive of Depreciation and Amortization

Technology & Analytics Solutions’ cost of revenues, exclusive of depreciation and amortization, increased $92 million, or 10.0%, in the third quarter of 2025 over the same period in 2024. This increase included a constant currency increase of approximately $77 million, or 8.4%.

Technology & Analytics Solutions’ cost of revenues, exclusive of depreciation and amortization, increased $252 million, or 9.3%, in the first nine months of 2025 over the same period in 2024. This increase included a constant currency increase of approximately $236 million, or 8.7%.

The constant currency increase for the three and nine months ended September 30, 2025 was primarily related to an increase in compensation and related expenses and to a lesser extent in reimbursed expenses to support revenue growth.

Selling, General and Administrative Expenses

Technology & Analytics Solutions’ selling, general and administrative expenses increased $20 million, or 8.8%, in the third quarter of 2025 as compared to the same period in 2024, which included a constant currency increase of approximately $14 million, or 6.2%.

Technology & Analytics Solutions’ selling, general and administrative expenses increased $33 million, or 4.8%, in the first nine months of 2025 as compared to the same period in 2024, which included a constant currency increase of approximately $27 million, or 4.0%.

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The constant currency increase for the nine months ended September 30, 2025 was primarily related to an increase in IT-related expenses.

Research & Development Solutions

						Three Months Ended September 30,												Change
(in millions)						2025						2024						$						%
Revenues						$	2,260					$	2,162					$	98					4.5		%
Cost of revenues, exclusive of depreciation and amortization						1,532						1,442						90						6.2
Selling, general and administrative expenses						232						222						10						4.5
Segment profit						$	496					$	498					$	(2)					(0.4)		%

						Nine Months Ended September 30,												Change
(in millions)						2025						2024						$						%
Revenues						$	6,563					$	6,404					$	159					2.5		%
Cost of revenues, exclusive of depreciation and amortization						4,481						4,268						213						5.0
Selling, general and administrative expenses						675						666						9						1.4
Segment profit						$	1,407					$	1,470					$	(63)					(4.3)		%

Backlog

Research & Development Solutions’ contracted backlog increased from $31.1 billion as of December 31, 2024 to $32.4 billion as of September 30, 2025, and we expect approximately $8.1 billion of this backlog to convert to revenues in the next twelve months.

Revenues

Research & Development Solutions’ revenues were $2,260 million for the third quarter of 2025, an increase of $98 million, or 4.5%, over the same period in 2024. This increase was comprised of constant currency revenue growth of approximately $73 million, or 3.4%, reflecting revenue growth primarily in the Americas region and to a lesser extent in the Asia-Pacific region.

Research & Development Solutions’ revenues were $6,563 million for the first nine months of 2025, an increase of $159 million, or 2.5%, over the same period in 2024. This increase was comprised of constant currency revenue growth of approximately $123 million, or 1.9%, reflecting revenue growth primarily in the Asia-Pacific region and to a lesser extent in the Americas region.

The constant currency revenue growth for the three and nine months ended September 30, 2025 was primarily the result of volume-related increases in clinical services. The constant currency revenue growth was impacted by a decrease in COVID-19 related work.

Cost of Revenues, exclusive of Depreciation and Amortization

Research & Development Solutions’ cost of revenues, exclusive of depreciation and amortization, increased $90 million, or 6.2%, in the third quarter of 2025 over the same period in 2024. This increase included a constant currency increase of approximately $82 million, or 5.7%.

Research & Development Solutions’ cost of revenues, exclusive of depreciation and amortization, increased $213 million, or 5.0% in the first nine months of 2025 over the same period in 2024. This increase included a constant currency increase of approximately $223 million, or 5.2%.

The constant currency increase for the three and nine months ended September 30, 2025 was primarily related to an increase in compensation and related expenses and to a lesser extent in reimbursed expenses as a result of volume-related increases in clinical services.

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Selling, General and Administrative Expenses

Research & Development Solutions’ selling, general and administrative expenses increased $10 million, or 4.5%, in the third quarter of 2025 as compared to the same period in 2024, which included a constant currency increase of approximately $9 million, or 4.1%.

Research & Development Solutions’ selling, general and administrative expenses increased $9 million, or 1.4% in the first nine months of 2025 as compared to the same period in 2024, which included a constant currency increase of approximately $10 million, or 1.5%.

The constant currency increase for the three and nine months ended September 30, 2025 was primarily related to an increase in compensation and related expenses.

Contract Sales & Medical Solutions

						Three Months Ended September 30,												Change
(in millions)						2025						2024						$						%
Revenues						$	209					$	180					$	29					16.1		%
Cost of revenues, exclusive of depreciation and amortization						181						154						27						17.5
Selling, general and administrative expenses						15						14						1						7.1
Segment profit						$	13					$	12					$	1					8.3		%

						Nine Months Ended September 30,												Change
(in millions)						2025						2024						$						%
Revenues						$	578					$	541					$	37					6.8		%
Cost of revenues, exclusive of depreciation and amortization						499						462						37						8.0
Selling, general and administrative expenses						43						45						(2)						(4.4)
Segment profit						$	36					$	34					$	2					5.9		%

Revenues

Contract Sales & Medical Solutions’ revenues were $209 million for the third quarter of 2025, an increase of $29 million, or 16.1%, over the same period in 2024. This increase was comprised of constant currency revenue growth of approximately $25 million, or 13.9%, reflecting revenue growth primarily in the Europe and Africa region and to a lesser extent in the Asia-Pacific region.

Contract Sales & Medical Solutions’ revenues were $578 million in the first nine months of 2025, an increase of $37 million, or 6.8%, over the same period in 2024. This increase was comprised of constant currency revenue growth of approximately $32 million, or 5.9%, reflecting revenue growth primarily in the Europe and Africa region and to a lesser extent in the Asia-Pacific region.

The constant currency revenue growth for the three and nine months ended September 30, 2025 was primarily due to volume-related increases in services performed.

Cost of Revenues, exclusive of Depreciation and Amortization

Contract Sales & Medical Solutions’ cost of revenues, exclusive of depreciation and amortization, increased $27 million, or 17.5%, in the third quarter of 2025 as compared to the same period in 2024. This increase included a constant currency increase of approximately $24 million, or 15.6%.

Contract Sales & Medical Solutions’ cost of revenues, exclusive of depreciation and amortization, increased $37 million, or 8.0%, in the first nine months of 2025 as compared to the same period in 2024. This increase included a constant currency increase of approximately $32 million, or 6.9%.

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The constant currency increase for the three and nine months ended September 30, 2025 was primarily related to an increase in compensation and related expenses.

Selling, General and Administrative Expenses

Contract Sales & Medical Solutions’ selling, general and administrative expenses increased $1 million, or 7.1%, in the third quarter of 2025 as compared to the same period in 2024. This increase included a constant currency increase of $1 million or 7.1%.

Contract Sales & Medical Solutions’ selling, general and administrative expenses decreased $2 million, or 4.4%, in the first nine months of 2025 as compared to the same period in 2024. This decrease included a constant currency decrease of approximately $1 million, or 2.2%.

The constant currency increase for the three months ended September 30, 2025 and the decrease for the nine months ended September 30, 2025 was primarily related to changes in compensation and related expenses.

Liquidity and Capital Resources

Overview

We assess our liquidity in terms of our ability to generate cash to fund our operating, investing and financing activities. Our principal source of liquidity is operating cash flows. In addition to operating cash flows, other significant factors that affect our overall management of liquidity include: capital expenditures, acquisitions, investments, debt service requirements, equity repurchases, adequacy of our revolving credit and receivables financing facilities, and access to the capital markets.

We manage our worldwide cash requirements by monitoring the funds available among our subsidiaries and determining the extent to which those funds can be accessed on a cost-effective basis. The repatriation of cash balances from certain of our subsidiaries could have adverse tax consequences; however, those balances are generally available without legal restrictions to fund ordinary business operations. We have and expect to transfer cash from those subsidiaries to the United States and to other international subsidiaries when it is cost effective to do so.

We had a cash balance of $1,814 million as of September 30, 2025 ($656 million of which was in the United States), an increase from $1,702 million as of December 31, 2024.

Based on our current operating plan, we believe that our available cash and cash equivalents, future cash flows from operations and our ability to access funds under our revolving credit and receivables financing facilities will enable us to fund our operating requirements, capital expenditures, contractual obligations, and meet debt obligations for at least the next 12 months. We regularly evaluate our debt arrangements, as well as market conditions, and from time to time we may explore opportunities to modify our existing debt arrangements or pursue additional financing arrangements that could result in the issuance of new debt securities by us or our affiliates. We may use our existing cash, cash generated from operations or dispositions of assets or businesses and/or proceeds from any new financing arrangements or issuances of debt or equity securities to repay or reduce some of our outstanding obligations, to repurchase shares from our stockholders or for other purposes. As part of our ongoing business strategy, we also continually evaluate new acquisition, expansion and investment possibilities or other strategic growth opportunities, as well as potential dispositions of assets or businesses, as appropriate, including dispositions that may cause us to recognize a loss on certain assets. Should we elect to pursue any such transaction, we may seek to obtain debt or equity financing to facilitate those activities. Our ability to enter into any such potential transactions and our use of cash or proceeds is limited to varying degrees by the terms and restrictions contained in our existing debt arrangements. We cannot provide assurances that we will be able to complete any such financing arrangements or other transactions on favorable terms or at all.

Equity Repurchase Program

On February 5, 2025, our Board of Directors increased the stock repurchase authorization under our equity repurchase program (the "Repurchase Program") with respect to the repurchase of our common stock by an additional $2,000 million, which increased the total amount that has been authorized under the Repurchase Program to $13,725 million. The Repurchase Program does not obligate us to repurchase any particular amount of common stock, and it may be modified, extended, suspended or discontinued at any time.

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During the nine months ended September 30, 2025, we repurchased 6.4 million shares of our common stock for $1,032 million under the Repurchase Program. As of September 30, 2025, we had remaining authorization to repurchase up to $1,981 million of our common stock under the Repurchase Program. In addition, from time to time, we have repurchased and may continue to repurchase common stock through private or other transactions outside of the Repurchase Program.

Debt

As of September 30, 2025, we had $15,034 million of total indebtedness, excluding $1,995 million of additional available borrowings under our revolving credit facility. Our long-term debt arrangements contain customary restrictive covenants and, as of September 30, 2025, we believe we were in compliance with our restrictive covenants in all material respects.

Senior Secured Credit Facilities

On March 10, 2025, we entered into an amendment (the “Amendment”) to our Fifth Amended and Restated Credit Agreement. The Amendment, among other changes, established a new incremental Term B-5 dollar loan facility in an aggregate principal amount equal to $1,985 million (the “Incremental Term B-5 Dollar Facility”). Proceeds of the Incremental Term B-5 Dollar Facility were applied to refinance our existing Term B-4 dollar loans and repay in full our existing Term B-2 Euro loans. In connection with this Amendment, we recognized a $4 million loss on extinguishment of debt, which includes fees and related expenses.

As of September 30, 2025, our Fifth Amended and Restated Credit Agreement provided financing through the senior secured credit facilities of up to $6,448 million, which consisted of $4,453 million principal amounts of debt outstanding, and $1,995 million of available borrowing capacity on the revolving credit facility and standby letters of credit. See Note 7 to our condensed consolidated financial statements included elsewhere in this Quarterly Report on Form 10-Q for additional details regarding our credit arrangements.

Senior Notes

During the three months ended September 30, 2025, the Company's Euro denominated 2.875% Senior Notes due 2025 matured and were repaid.

On June 4, 2025, we completed the issuance and sale of $2,000 million in gross proceeds of 6.250% senior notes due 2032 (the "Senior Notes"). The net proceeds from the notes offering were used to repay existing borrowings under our revolving credit facility and to pay fees and expenses related to the Senior Notes offering, with any excess proceeds used for general corporate purposes. See Note 7 to our condensed consolidated financial statements included elsewhere in this Quarterly Report on Form 10-Q for additional details regarding our credit arrangements.

Receivables Financing Facility

As of September 30, 2025, no additional amounts of revolving loans were available under the receivables financing facility.

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Nine months ended September 30, 2025 and 2024

Cash Flow from Operating Activities

						Nine Months Ended September 30,
(in millions)						2025						2024
Net cash provided by operating activities						$	1,919					$	1,831

Cash provided by operating activities increased $88 million during the first nine months of 2025 as compared to the same period in 2024. The increase was primarily driven by an increase in cash from unearned income ($294 million), offset by a decrease in cash from accounts receivable and unbilled services ($111 million), cash from other operating assets and liabilities ($57 million), which includes $42 million in cash received related to the termination of our previous cross-currency swaps during the first nine months of 2025, and cash-related net income ($38 million).

Cash Flow from Investing Activities

						Nine Months Ended September 30,
(in millions)						2025						2024
Net cash used in investing activities						$	(1,201)					$	(1,134)

Cash used in investing activities increased $67 million during the first nine months of 2025 as compared to the same period in 2024, primarily driven by more cash used for acquisitions of businesses ($149 million), cash used for investments in debt and equity securities ($18 million), and cash used in other ($1 million), offset by more proceeds from sale of property, equipment, and software ($50 million), less cash used for investments in unconsolidated affiliates, net ($40 million), less cash used for acquisitions of property, equipment and software ($9 million), and more cash from sales of marketable securities, net ($2 million).

Cash Flow from Financing Activities

						Nine Months Ended September 30,
(in millions)						2025						2024
Net cash used in financing activities						$	(685)					$	(503)

Cash used in financing activities increased $182 million during the first nine months of 2025 as compared to the same period in 2024, primarily due to more cash payments for debt and principal payments on finance leases ($2,546 million), repurchase of common stock ($832 million), revolving credit facilities, net of repayments ($725 million), contingent consideration and deferred purchase price accruals ($14 million), other ($11 million), and cash used for payments related to employee stock incentive plans ($5 million), offset by more proceeds from issuance of debt, net ($3,951 million).

Information about our Guarantors and the Issuer of our Guaranteed Securities

IQVIA Inc. (the “Issuer”), a wholly owned subsidiary of IQVIA Holdings Inc., completed the issuance and sale of $1,250 million in gross proceeds of the Issuer’s 6.250% senior secured notes due 2029 (the “2029 Senior Secured Notes”) on November 28, 2023, and completed the issuance and sale of $750 million in gross proceeds of the Issuer’s 5.700% senior secured notes due 2028 (the “2028 Senior Secured Notes”) on May 23, 2023.

In February 2024, the Issuer completed an exchange offer in which it issued $1,250 million aggregate principal amount of 6.250% Senior Secured Notes due 2029 registered under the Securities Act (the “2029 Registered Notes”) and $750 million aggregate principal amount of 5.700% Senior Secured Notes due 2028 registered under the Securities Act (the “2028 Registered Notes” and, together with the 2029 Registered Notes, the 2029 Senior Secured Notes, and the 2028 Senior Secured Notes, the “Notes”) in exchange for the same principal amount and substantially identical terms of the 2029 Senior Secured Notes and 2028 Senior Secured Notes, respectively.

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The accompanying summarized financial information has been prepared and presented pursuant to Rule 3-10 of Regulation S-X, “Financial Statements of Guarantors and Issuers of Guaranteed Securities Registered or Being Registered,” and Rule 13-01 of Regulation S-X, “Financial Disclosures about Guarantors and Issuers of Guaranteed Securities and Affiliates Whose Securities Collateralized a Registrant’s Securities.” Each of our current direct and indirect material U.S. wholly owned restricted subsidiaries (excluding IQVIA Solutions Japan LLC and IQVIA Services Japan LLC) (the "Guarantor subsidiaries" and, together with IQVIA Holdings Inc., the “Guarantors”), have jointly and severally, irrevocably and unconditionally, on a senior secured basis, guaranteed the obligations under the Notes.

The following presents the summarized financial information on a combined basis for IQVIA Holdings Inc. (parent company), IQVIA Inc. (issuer of the guaranteed obligations) and the Guarantor subsidiaries, which are collectively referred to as the “obligated group.”

Each Guarantor subsidiary is consolidated by IQVIA Holdings Inc. as of September 30, 2025 and December 31, 2024. Refer to Exhibit 22.1 to this Quarterly Report on Form 10-Q for the detailed list of entities included within the obligated group as of September 30, 2025.

The guarantee of a Guarantor subsidiary with respect to the Notes will be automatically and unconditionally released and discharged and shall terminate and be of no further force and effect, and no further action by such Guarantor subsidiary, the Issuer, or U.S. Bank Trust Company, National Association, as trustee, be required upon the occurrence of any of the following:

a.any sale, exchange, issuance, disposition or transfer (by merger, amalgamation, consolidation or otherwise) of (i) the capital stock of such Guarantor, after which the applicable Guarantor is no longer a Restricted Subsidiary, or (ii) all or substantially all of the assets of such Guarantor, in each case if such sale, exchange, issuance, disposition or transfer is made in compliance with the applicable provisions of this Indenture;

b.the release or discharge of the guarantee by such Guarantor of indebtedness under the senior secured term loan facilities and the senior secured revolving credit facilities under that certain Fifth Amended and Restated Credit Agreement, or the release or discharge of such other guarantee that resulted in the creation of such Guarantee, except, in each case, a discharge or release by or as a result of payment of such Indebtedness or under such guarantee (it being understood that a release subject to a contingent reinstatement is still a release, and that if any such guarantee is so reinstated, such Guarantee shall also be reinstated to the extent that such Guarantor would then be required to provide a Guarantee pursuant to Section 4.11 of the Indenture);

c.the designation of any Restricted Subsidiary that is a Guarantor as an Unrestricted Subsidiary in compliance with the applicable provisions of the Indenture;

d.the exercise by the Issuer of its Legal Defeasance option or Covenant Defeasance option in accordance with Article VIII of the Indenture or the discharge of the Issuer’s obligations under the Indenture in accordance with the terms of this Indenture;

e.the merger, amalgamation or consolidation of any Guarantor with and into the Issuer or a Guarantor that is the surviving Person in such merger, amalgamation or consolidation, or upon the liquidation of a Guarantor following the transfer of all or substantially all of its assets, in each case in a transaction that complies with the applicable provisions of this Indenture; or

f.as described in Article IX of the Indenture.

Summarized Combined Financial Information of the Issuer and Guarantors:

Each entity in the summarized combined financial information follows the same accounting policies as previously disclosed in Note 1 of the consolidated financial statements of our 2024 Form 10-K. Information for the non-Guarantor subsidiaries has been excluded from the combined summarized financial information of the obligated group. The accompanying summarized combined financial information does not reflect investments of the obligated group in non-Guarantor subsidiaries. The financial information of the obligated group is presented on a combined basis; intercompany balances and transactions within the obligated group have been eliminated. The obligated group’s amounts due from and amounts due to non-Guarantor subsidiaries and related parties have been presented in separate line items.

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The following table contains summarized combined financial information from the Statements of Unaudited Condensed Consolidated Financial Position of the obligated group as of:

(in millions)						September 30, 2025						December 31, 2024
Total current assets (excluding amounts due from subsidiaries that are non-Guarantors)						$	599					$	935
Total noncurrent assets						$	10,894					$	10,937
Amounts due from subsidiaries that are non-Guarantors						$	4,663					$	4,952
Total current liabilities						$	5,120					$	3,792
Total noncurrent liabilities						$	12,223					$	12,333
Amounts due to subsidiaries that are non-Guarantors						$	7,190					$	6,341

The following table contains summarized combined financial information from the Statements of Unaudited Condensed Consolidated Operations of the obligated group:

						Nine months ended						Twelve months ended
(in millions)						September 30, 2025						December 31, 2024
Net revenues						$	5,039					$	6,661
Costs and expenses applicable to net revenues						$	3,157					$	4,145
Income from operations						$	1,074					$	1,259
Net income						$	117					$	554

Off-Balance Sheet Arrangements

We do not have any material off-balance sheet arrangements.

Contractual Obligations and Commitments

We have various contractual obligations, which are recorded as liabilities in our consolidated financial statements.

There have been no material changes, outside of the ordinary course of business, to our contractual obligations as previously disclosed in our 2024 Form 10-K.

Application of Critical Accounting Policies

There have been no material changes to our critical accounting policies as previously disclosed in our 2024 Form 10-K.

Item 3. Quantitative and Qualitative Disclosures About Market Risk

There have been no material changes to our quantitative and qualitative disclosures about market risk as compared to the quantitative and qualitative disclosures about market risk described in our 2024 Form 10-K.

Item 4. Controls and Procedures

Evaluation of Disclosure Controls and Procedures

Our management, with the participation of our Chief Executive Officer (“CEO”) and Chief Financial Officer (“CFO”), has evaluated the effectiveness of our disclosure controls and procedures (as defined in Rules 13a-15(e) and 15d-15(e)) under the Securities Exchange Act of 1934, as amended (“Exchange Act”) as of the end of the period covered by this Quarterly Report on Form 10-Q. Based on such evaluation, our CEO and CFO have concluded that as of such date, our disclosure controls and procedures were effective.

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Changes in Internal Control over Financial Reporting

There were no changes in our internal control over financial reporting identified in management’s evaluation pursuant to Rules 13a-15(d) or 15d-15(d) of the Exchange Act during the period covered by this Quarterly Report on Form 10-Q that materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.

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PART II—OTHER INFORMATION

Item 1. Legal Proceedings

We are party to legal proceedings incidental to our business. While the outcome of these matters could differ from management’s expectations, we do not believe that the resolution of these matters is reasonably likely to have a material adverse effect to our financial statements.

Information pertaining to legal proceedings can be found in Note 8 to the condensed consolidated financial statements included elsewhere in this Quarterly Report on Form 10-Q and is incorporated by reference herein.

Item 1A. Risk Factors

For a discussion of the risks relating to our business, see Part I—Item 1A—“Risk Factors” of our 2024 Form 10-K. There have been no material changes from the risk factors previously disclosed in our 2024 Form 10-K.

Item 2. Unregistered Sales of Equity Securities and Use of Proceeds

Recent Sales of Unregistered Securities

Not applicable.

Use of Proceeds from Registered Securities

Not applicable.

Purchases of Equity Securities by the Issuer

On October 30, 2013, our Board of Directors (the "Board") approved an equity repurchase program (the “Repurchase Program”) authorizing the repurchase of up to $125 million of our common stock. The Board increased the stock repurchase authorization under the Repurchase Program with respect to the repurchase of our common stock by $600 million, $1.5 billion, $2.0 billion, $1.5 billion, $2.0 billion, $2.0 billion, and $2.0 billion in 2015, 2016, 2017, 2018, 2019, 2022, and 2023, respectively. On February 5, 2025, the Board increased the stock repurchase authorization under the Repurchase Program with respect to the repurchase of the Company's common stock by an additional $2,000 million, which increased the total amount that has been authorized under the Repurchase Program to $13,725 million. The Repurchase Program does not obligate us to repurchase any particular amount of common stock, and it may be modified, extended, suspended or discontinued at any time. The timing and amount of repurchases are determined by our management based on a variety of factors such as the market price of our common stock, our corporate requirements, and overall market conditions. Purchases of our common stock may be made in open market transactions effected through a broker-dealer at prevailing market prices, in block trades, or in privately negotiated transactions. The Repurchase Program for common stock does not have an expiration date. In addition, from time to time, we have repurchased and may continue to repurchase common stock through private or other transactions outside of the Repurchase Program.

From inception of the Repurchase Program through September 30, 2025, we have repurchased a total of $11,744 million of our securities under the Repurchase Program.

During the nine months ended September 30, 2025, we repurchased 6.4 million shares of our common stock for $1,032 million under the Repurchase Program. See Note 9 to our condensed consolidated financial statements included elsewhere in this Quarterly Report on Form 10-Q for additional details regarding the Repurchase Program.

As of September 30, 2025, we had remaining authorization to repurchase up to $1,981 million of our common stock under the Repurchase Program.

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Since the merger between Quintiles and IMS Health, we have repurchased 91.0 million shares of our common stock at an average market price per share of $125.01 for an aggregate purchase price of $11,370 million both under and outside of the Repurchase Program. This includes shares withheld from employees to satisfy certain tax obligations due in connection with grants of stock under the IQVIA Holdings Inc. 2017 Incentive and Stock Award Plan (the “Plan”). The Plan provides for the withholding of shares to satisfy tax obligations. It does not specify a maximum number of shares that can be withheld for this purpose. The shares of common stock withheld to satisfy tax withholding obligations may be deemed to be “issuer purchases” of shares that are required to be disclosed pursuant to this Item.

The following table summarizes the monthly equity repurchase program activity for the three months ended September 30, 2025, and the approximate dollar value of shares that may yet be purchased pursuant to the Repurchase Program.

(in millions, except per share data)						Total Number of Shares Purchased						Average Price Paid Per Share						Total Number of Shares Purchased as Part of Publicly Announced Plans or Programs						Approximate Dollar Value of Shares That May Yet Be Purchased Under the Plans or Programs
July 1, 2025 — July 31, 2025						—						$	—					—						$	1,981
August 1, 2025 — August 31, 2025						—						$	—					—						$	1,981
September 1, 2025 — September 30, 2025						—						$	—					—						$	1,981
						—												—

Item 5. Other Information

In the third quarter of 2025, no director or officer (as defined in Exchange Act Rule 16a-1(f)) of IQVIA Holdings Inc. adopted or terminated a Rule 10b5-1 trading arrangement or non-Rule 10b5-1 trading arrangement for the purchase or sale of securities of IQVIA Holdings Inc., within the meaning of Item 408 of Regulation S-K.

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Item 6. Exhibits

The exhibits below are filed or furnished as a part of this report and are incorporated herein by reference.

Incorporated by Reference

Exhibit Number

Exhibit Description

Filed Herewith

Form

File No.

Exhibit

Filing Date

22.1

List of Subsidiary Guarantors and Affiliates who Collateralize the Company’s Securities.

X

31.1

Certification of Chief Executive Officer, pursuant to Rule 13a-14(a)/15d-14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.

X

31.2

Certification of Executive Vice President and Chief Financial Officer, pursuant to Rule 13a-14(a)/15d-14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.

X

32.1

Certification of Chief Executive Officer, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.

X

32.2

Certification of Executive Vice President and Chief Financial Officer, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.

X

101

Interactive Data Files Pursuant to Rule 405 of Regulation S-T: (i) Condensed Consolidated Statements of Income (unaudited), (ii) Condensed Consolidated Statements of Comprehensive Income (unaudited), (iii) Condensed Consolidated Balance Sheets (unaudited), (iv) Condensed Consolidated Statements of Cash Flows (unaudited), (v) Condensed Consolidated Statements of Stockholders’ Equity (unaudited) and (vi) Notes to Condensed Consolidated Financial Statements (unaudited). The instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the Inline XBRL document.

X

104

Cover Page Interactive Data File. The instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the Inline XBRL document.

X

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SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this Quarterly Report on Form 10-Q to be signed on its behalf by the undersigned, thereunto duly authorized on October 28, 2025.

IQVIA HOLDINGS INC.

/s/ Ronald E. Bruehlman

Ronald E. Bruehlman

Executive Vice President and Chief Financial Officer

(On behalf of the Registrant and as Principal Financial Officer)

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FAQ

What were IQV (IQVIA) Q3 2025 revenue and EPS?

Revenue was $4.1 billion and diluted EPS was $1.93.

How did IQVIA’s segments perform in Q3 2025?

Technology & Analytics Solutions $1.631B; Research & Development Solutions $2.260B; Contract Sales & Medical Solutions $209M.

What was IQVIA’s operating cash flow year‑to‑date?

Net cash provided by operating activities was $1.919 billion for the nine months ended September 30, 2025.

How much stock did IQVIA repurchase in 2025 year‑to‑date?

The company repurchased 6.4 million shares for $1.032 billion.

What new debt did IQVIA issue in 2025?

IQVIA issued $2.0 billion of 6.250% senior notes due 2032 and entered a $1.985 billion Term B‑5 loan to refinance prior loans.

What are IQVIA’s remaining performance obligations (RPO)?

RPO totaled $34.4 billion; about 30% expected to be recognized within 12 months and 85% within five years.

How many IQVIA shares were outstanding recently?

170.3 million common shares were outstanding as of October 20, 2025.