[Form 4] Jazz Pharmaceuticals plc Insider Trading Activity

Rhea-AI Filing Summary

Jazz Pharmaceuticals (JAZZ) director Heather McSharry reported an option exercise and share sale. On 11/20/2025 she exercised 3,415 non-qualified stock options at an exercise price of $138.08 per share, acquiring the same number of ordinary shares.

On the same date, she sold 3,415 ordinary shares at a price of $177.7823 per share. After these transactions, she directly beneficially owned 20,449 ordinary shares of Jazz Pharmaceuticals. The exercised options were originally granted in August 2016, fully vested by August 2017, and were scheduled to expire on 08/10/2026.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
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hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

McSharry Heather Ann

(Last) (First) (Middle)

5TH FL, WATERLOO EXCHANGE

WATERLOO RD

(Street)

DUBLIN 4 L2

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Jazz Pharmaceuticals plc [ JAZZ ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
11/20/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Ordinary Shares	11/20/2025		M		3,415	A	$138.08	23,864	D
Ordinary Shares	11/20/2025		S		3,415	D	$177.7823	20,449	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Non-Qualified Stock Option (right to buy)	$138.08	11/20/2025		M			3,415	(1)	08/10/2026	Ordinary Shares	3,415	$0.0	0	D

Explanation of Responses:

1. This non-qualified stock option was granted on August 11, 2016 and vested over a period of one year from September 1, 2016. The options were fully vested as of August 1, 2017.

	By: /s/Adam Guttmann, as attorney in fact For: Heather McSharry	11/24/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What insider transaction did JAZZ director Heather McSharry report?

Heather McSharry reported exercising 3,415 non-qualified stock options in Jazz Pharmaceuticals and selling 3,415 ordinary shares on 11/20/2025.

At what prices were the JAZZ option exercise and share sale executed?

The options were exercised at an exercise price of $138.08 per share, and the resulting 3,415 ordinary shares were sold at $177.7823 per share.

How many JAZZ shares does Heather McSharry own after this Form 4 transaction?

Following the reported transactions, Heather McSharry directly beneficially owned 20,449 ordinary shares of Jazz Pharmaceuticals.

What type of derivative security did the JAZZ director exercise?

She exercised a non-qualified stock option (right to buy) covering 3,415 ordinary shares of Jazz Pharmaceuticals.

When were the exercised JAZZ stock options originally granted and when did they vest?

The non-qualified stock option was granted on August 11, 2016 and vested over one year from September 1, 2016, becoming fully vested as of August 1, 2017.

When was the expiration date for the exercised JAZZ stock options?

The non-qualified stock option exercised on 11/20/2025 had an expiration date of 08/10/2026.