As filed with the Securities and Exchange Commission on June 30, 2025 
Registration No. 333-210521 
Registration No. 333-218544 
Registration No. 333-223664 
Registration No. 333-230155 
Registration No. 333-237181 
Registration No. 333-252691 
Registration No. 333-252692 
Registration No. 333-256853 
Registration No. 333-268969 
 
 
 
 UNITED STATES 
SECURITIES AND EXCHANGE COMMISSION 
Washington, D.C. 20549 
 
 
POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO.
333-210521 
 POST-EFFECTIVE AMENDMENT NO. 1 TO FORM
S-8 REGISTRATION STATEMENT NO. 333-218544 
POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO.
333-223664 
 POST-EFFECTIVE AMENDMENT NO. 1 TO FORM
S-8 REGISTRATION STATEMENT NO. 333-230155 
POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO.
333-237181 
 POST-EFFECTIVE AMENDMENT NO. 1 TO FORM
S-8 REGISTRATION STATEMENT NO. 333-252691 
POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO.
333-252692 
 POST-EFFECTIVE AMENDMENT NO. 1 TO FORM
S-8 REGISTRATION STATEMENT NO. 333-256853 
POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO.
333-268969 
 UNDER 
THE SECURITIES ACT OF 1933 
 
 
KINETA, INC. 
 (By
Kineta, LLC, as successor by merger to Kineta, Inc.) 
 (Exact name of registrant as specified in its charter)
 
 
 
|  |  |  | 
| Delaware |   | 20-8436652 | 
| (State or other jurisdiction of incorporation or organization) |   | (IRS employer identification number) | 
 c/o TuHURA Biosciences, Inc. 
10500 University Center Dr., Suite 110 
Tampa, Florida 33612 
(813) 875-6600 
 (Address,
including zip code, and telephone number, including area code, of Registrants principal executive officers) 
 Proteostasis
Therapeutics, Inc. 2008 Equity Incentive Plan 
 Proteostasis Therapeutics, Inc. 2016 Stock Option and Incentive Plan 
Proteostasis Therapeutics, Inc. 2016 Employee Stock Purchase Plan 
Yumanity Therapeutics, Inc. Amended and Restated 2018 Stock Option and Grant Plan 
Yumanity Therapeutics, Inc. 2021 Inducement Plan 
Inducement Non-Qualified Stock Option Agreement 
Kineta, Inc. Amended and Restated 2008 Stock Plan 
Kineta, Inc. 2010 Equity Incentive Plan, as amended 
Kineta, Inc. 2020 Equity Incentive Plan 
Kineta, Inc. 2022 Equity Incentive Plan 
(Full title of the Plans) 
James A. Bianco, M.D. 
President 
 c/o TuHURA
Biosciences, Inc. 
 10500 University Center Dr., Suite 110 
Tampa, Florida 33612 
(813) 875-6600 
 (Name,
Address and Telephone Number, including Area Code, of Agent for Service) 
 
 
Copies to: 
|  | 
|  | 
| Curt P. Creely, Esq. Garrett F. Bishop, Esq. Foley & Lardner LLP 100 North Tampa Street, Suite 2700 Tampa, Florida 33612 (813) 225-4122  | 
  
 
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated
filer, a smaller reporting company, or an emerging growth company. See the definitions of large accelerated filer, accelerated filer, smaller reporting company and emerging growth company in Rule 12b-2 of the Exchange Act. 
  
|  |  |  |  |  |  |  | 
| Large accelerated filer |   | ☐ |    | Accelerated filer |   | ☐ | 
|  |  |  |  | 
| Non-accelerated filer |   | ☒ |    | Smaller reporting company |   | ☒ | 
|  |  |  |  | 
| Emerging growth company |   | ☐ |    |  |   |  | 
 If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period
for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐