[Form 4] Klotho Neurosciences, Inc. Insider Trading Activity

Rhea-AI Filing Summary

Joseph Sinkule, who serves as Chief Executive Officer and a Director of Klotho Neurosciences, acquired 400,000 shares of the company's common stock on 09/25/2025. The filing states these shares were returned to him after he canceled a portion of a previously-reported non-recourse loan that had used the shares as collateral. After this transaction, Sinkule beneficially owns 4,846,700 shares, which the filing clarifies includes 1,000,000 shares issuable upon exercise of incentive options. The Form 4 is signed and dated 09/29/2025 and reports the change as a non-derivative acquisition by an executive who is also a director.

Positive

• CEO and Director regained 400,000 shares via cancellation of a non-recourse loan, increasing his direct reported holdings.
• Clear disclosure of the transaction mechanism (loan cancellation and return of pledged shares) and post-transaction holdings of 4,846,700 shares.

Negative

• None.

Insights

Corporate Governance Expert

TL;DR: CEO/director regained 400,000 shares after canceling part of a non-recourse loan, increasing his reported beneficial holdings to 4.85 million shares.

This Form 4 documents a routine insider transaction in which the reporting person canceled indebtedness secured by pledged shares and thereby reacquired the pledged shares. From a governance perspective, the filing is transparent about the mechanism (loan cancellation) and the resulting ownership level, and it discloses the portion of holdings that are option-based (1,000,000 shares issuable). The action does not itself indicate a change in company operations or financial condition; it primarily affects insider ownership reporting.

Securities/Insider Transactions Analyst

TL;DR: Reported acquisition code J reflects return of pledged shares from canceled non-recourse loan; the transaction increases direct holdings on the record.

From a securities compliance angle, the use of transaction code J is appropriate for the described loan cancellation and release of pledged collateral. The Form 4 lists the post-transaction beneficial ownership as 4,846,700 shares, allowing investors and regulators to track insider concentration. No derivative transactions or new option grants are reported in this filing.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
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hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person^*

SINKULE JOSEPH

(Last) (First) (Middle)

1300 SOUTH BOULEVARD SUITE D

(Street)

CHARLOTTE NC 28203

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Klotho Neurosciences, Inc. [ KLTO ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Executive Officer

3. Date of Earliest Transaction (Month/Day/Year)
09/25/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	09/25/2025		J		400,000	A	(1)	4,846,700(2)	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. On September 25, 2025, the Reporting Person canceled a portion of a previously-reported non-recourse loan, and received the shares back that were pledged as collateral.

2. Includes 1,000,000 shares issuable upon the exercise of incentive options.

Remarks:

	Joseph Sinkule	09/29/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What transaction did Joseph Sinkule report on Form 4 for KLTO?

The Form 4 reports that Joseph Sinkule acquired 400,000 common shares on 09/25/2025 when he canceled part of a previously-reported non-recourse loan and received pledged shares back as collateral.

How many KLTO shares does the reporting person beneficially own after the transaction?

The filing states the reporting person beneficially owns 4,846,700 shares following the reported transaction.

Does the reported ownership include options or exercisable shares?

Yes. The filing explicitly notes that the total includes 1,000,000 shares issuable upon exercise of incentive options.

What does transaction code J indicate on this Form 4?

Transaction code J is used here to indicate the return of shares previously pledged as collateral after cancellation of a loan, as described in the filing.

When was the Form 4 signed by the reporting person?

The Form 4 is signed by Joseph Sinkule and dated 09/29/2025.