Welcome to our dedicated page for KIORA PHARMACEUTICALS SEC filings (Ticker: KPRX), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
Kiora Pharmaceuticals filings document a clinical-stage ophthalmology issuer focused on small-molecule programs for retinal disease. Current disclosures cover results of operations and financial condition, research-and-development progress for KIO-301 and KIO-104, collaboration reimbursements, and clinical or regulatory updates tied to the company’s development pipeline.
Material-event reports also record securities purchase agreements, common stock, pre-funded warrants and Tranche A warrants issued in private placements, along with executive changes. Proxy materials address board governance, executive compensation, equity awards, shareholder voting matters and related risk-factor disclosures for a Nasdaq-listed Delaware corporation.
Kiora Pharmaceuticals announced that Chief Development Officer Eric J. Daniels, M.D., MBA will resign effective April 17, 2026 to pursue another opportunity. The company stated his departure is not due to any disagreement over operations, policies, or practices and has begun a search for his successor.
Kiora emphasized continued progress in its retinal disease pipeline. In the ABACUS-2 Phase 2 trial of KIO-301, a planned safety review allowed enrollment of remaining patients in the 50µg dose cohort and cleared initiation of the 100µg cohort. In the KLARITY Phase 2 trial of KIO-104, all planned safety checkpoints have been cleared and patient enrollment is ongoing.
Kiora Pharmaceuticals reported a net loss of $10.8 million for 2025, compared with net income of $3.6 million in 2024, mainly because 2024 included $16.0 million of collaboration revenue and 2025 recorded a $4.6 million in-process R&D impairment related to KIO-104.
Revenue was zero in 2025, while operating expenses rose as R&D increased to $10.8 million with two Phase 2 trials underway and G&A reached $5.7 million. Kiora ended 2025 with $17.1 million in cash, cash equivalents and short-term investments plus $3.5 million in receivables and projects its cash runway into late 2027.
Pipeline progress included advancing KIO-301 and KIO-104 into active Phase 2 studies in retinal diseases and signing an option agreement with Senju Pharmaceutical with potential value of up to $110 million plus royalties, alongside continued work on the KIO-300 ion-channel modulator platform.
Kiora Pharmaceuticals, Inc. is a clinical-stage specialty pharmaceutical company focused on therapies for retinal diseases. Its lead candidate, KIO-301, is a small-molecule “photoswitch” being developed for late-stage retinitis pigmentosa and other inherited retinal dystrophies. A Phase 1b trial showed safety and vision-related improvements, and a 36‑patient Phase 2 ABACUS‑2 trial in RP is enrolling under a global co-development agreement with Théa Open Innovation, which funds all KIO‑301 R&D.
The company is also advancing KIO-104, an intravitreal DHODH inhibitor for retinal inflammation such as diabetic macular edema and posterior non‑infectious uveitis, with a Phase 2 KLARITY trial dosing patients. A topical DHODH inhibitor, KIO‑101, is being positioned for partnering in ocular manifestations of autoimmune diseases. Kiora reported a $10.8 million net loss for the year ended December 31, 2025, versus net income of $3.6 million in 2024, and held $17.1 million in cash and short-term investments, which it expects to fund operations into late 2027. As of March 21, 2026, there were 3,950,628 shares of common stock outstanding.
Kiora Pharmaceuticals Chief Development Officer Eric Joseph Daniels reported a small tax-related share disposition. On March 3, 2026, he transferred 238 shares of common stock at $2.02 per share to satisfy tax withholding obligations. After this transaction, he directly held 26,137 common shares.
Kiora Pharmaceuticals President and CEO Brian M. Strem reported a tax-related stock transaction. On March 3, 2026, he disposed of 238 shares of common stock at $2.02 per share as a tax-withholding disposition, a method of paying tax obligations using shares. After this transaction, he directly owned 45,865 common shares.
Kiora Pharmaceuticals Inc. received an amended Schedule 13G from Rosalind Advisors Inc., Rosalind Master Fund L.P., and portfolio managers Steven Salamon and Gilad Aharon reporting beneficial ownership tied to warrants for up to 464,676 common shares, or 9.9% of the company based on 3,677,935 shares outstanding as of November 5, 2025. These shares are issuable upon exercise of warrants that include a 9.99% beneficial ownership blocker, so as of the December 31, 2025 event date the reporting persons state they could not exercise the warrants. The filers characterize the position as held in the ordinary course of business and state it is not for the purpose of changing or influencing control.
Kiora Pharmaceuticals (KPRX) received an amended Schedule 13G from Nantahala Capital Management and affiliates reporting beneficial ownership of 9.99% of the common stock as of September 30, 2025. The group reports 363,712 shares beneficially owned, which includes 207,285 shares that may be acquired within sixty days through the exercise of warrants.
The reporting persons disclose 0 shares with sole voting or dispositive power and 363,712 shares with shared voting and dispositive power. The filing is certified as securities held in the ordinary course and not for the purpose of changing or influencing control.
Kiora Pharmaceuticals (KPRX) furnished an 8-K announcing it issued a press release with financial results for the quarter ended September 30, 2025 and an update on clinical development progress. The press release is included as Exhibit 99.1.
The company stated the information under Item 2.02, including Exhibit 99.1, is furnished, not filed, and will not be incorporated by reference into other filings unless specifically stated. Kiora’s common stock trades on NASDAQ under the symbol KPRX.
Kiora Pharmaceuticals (KPRX) filed its Q3 2025 Form 10‑Q, showing a small quarterly net income of $26,806, driven by lower operating expenses from collaboration credits and a reduction in contingent consideration fair value. For the nine months, the company recorded a net loss of $4,318,633.
Liquidity remained solid with Cash and Cash Equivalents of $5,508,899 and Short‑Term Investments of $13,866,546. Management states these resources are sufficient to fund planned operations into late 2027. Total assets were $29,863,454 and total liabilities were $7,452,712.
Operating expenses in the quarter benefited from Collaboration Credits of $(1,658,248) and a Change in Fair Value of Contingent Consideration of $(1,721,033), offsetting R&D and G&A. The balance sheet includes Deferred Collaboration Revenue of $1,250,000 tied to an option agreement with Senju.
The company highlighted its TOI license executed in 2024 and ongoing ABACUS‑2 activities. Common shares outstanding were 3,433,491 as of September 30, 2025, and 3,677,935 as of November 5, 2025.
Kiora Pharmaceuticals, Inc. (KPRX) received a Schedule 13G/A reporting that ADAR1-related parties beneficially own 362,527 to 365,179 shares of Common Stock, representing 9.9% of the 3,433,491 shares outstanding as of June 30, 2025. The filing attributes ownership to ADAR1 Capital Management, ADAR1 Capital Management GP, LLC, and Daniel Schneeberger in his managerial and individual capacities. Reported holdings include common shares and shares underlying pre-funded and milestone warrants, while excluding larger blocks of additional warrant shares subject to a 9.99% beneficial ownership limitation. Signatures are dated August 14, 2025.