Kazia Therapeutics (NASDAQ: KZIA) updates ADS prospectus

Rhea-AI Filing Summary

Kazia Therapeutics Limited (KZIA) has filed a prospectus supplement to its Form F-1 registration statement covering 266,666 American Depositary Shares (ADSs), each ADS representing 500 ordinary shares for a total of 133,333,000 ordinary shares. The supplement updates the existing prospectus by incorporating a Form 6-K dated August 31, 2026, which reports that on August 28, 2026 the company launched a new website at www.kaziatx.com, replacing prior references to www.kaziatherapeutics.com. The ADSs trade on the Nasdaq Capital Market under the symbol KZIA, and the last reported sale price on August 28, 2026 was $13.58 per ADS. The information in this Form 6-K is also incorporated by reference into Kazia’s registration statements on Form F-3 (File Nos. 333-276091, 333-281937 and 333-294392).

Key Figures

ADSs covered: 266,666 American Depositary Shares Ordinary shares represented: 133,333,000 ordinary shares ADS ratio: 1 ADS represents 500 ordinary shares +3 more

6 metrics

ADSs covered 266,666 American Depositary Shares Number of ADSs referenced in the prospectus supplement

Ordinary shares represented 133,333,000 ordinary shares Total ordinary shares represented by the ADSs in the supplement

ADS ratio 1 ADS represents 500 ordinary shares Implied from 266,666 ADSs representing 133,333,000 ordinary shares

Nasdaq last reported sale price $13.58 per ADS Last reported sale price on August 28, 2026

Website launch date August 28, 2026 Date Kazia Therapeutics launched its new website at www.kaziatx.com

Prospectus supplement date August 31, 2026 Date of the prospectus supplement and related Form 6-K

Key Terms

American Depositary Shares, prospectus supplement, foreign private issuer, incorporates by reference

4 terms

American Depositary Shares financial

"266,666 American Depositary Shares representing 133,333,000 Ordinary Shares"

American depositary shares (ADSs) are a way for investors in the United States to buy shares of foreign companies without dealing with international markets directly. They represent ownership in a foreign company's stock and are traded on U.S. stock exchanges, making it easier for American investors to buy, sell, and own parts of companies from around the world.

prospectus supplement regulatory

"This prospectus supplement is being filed to update and supplement the information"

A prospectus supplement is an additional document provided alongside a company's main offering details, offering updated or extra information about a specific financial product being sold. It helps investors understand the latest terms, risks, and details of the investment, similar to how an update or revision clarifies or expands on original instructions, ensuring they have current and complete information before making a decision.

foreign private issuer regulatory

"FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16"

A foreign private issuer is a company organized outside the United States that meets tests showing it is primarily foreign-controlled and therefore qualifies for a different set of U.S. reporting rules. For investors, that means the company files less frequent or differently formatted disclosures with U.S. regulators and may follow home-country accounting and governance practices, so buying its stock is like dining at a well-reviewed restaurant that follows its home kitchen’s rules instead of the local menu — you get access but should check what standards apply.

incorporates by reference regulatory

"The Company hereby incorporates by reference the information contained herein"

Offering Details

shelf

Offering

Offering Type shelf

FAQ

What does the KZIA 424B3 prospectus supplement filed on August 31, 2026 do?

It updates the existing Form F-1 prospectus for Kazia Therapeutics (KZIA) by incorporating an August 31, 2026 Form 6-K, which reports the launch of a new corporate website and updates prior website references.

How many securities are covered by Kazia Therapeutics’ KZIA prospectus supplement?

The prospectus supplement relates to 266,666 American Depositary Shares, representing 133,333,000 ordinary shares of Kazia Therapeutics Limited, as part of its Form F-1 registration statement.

What website change did KZIA announce in the incorporated Form 6-K?

Kazia Therapeutics announced that on August 28, 2026 it launched a new website at www.kaziatx.com, and any prior references to www.kaziatherapeutics.com in its SEC filings should now be read as referring to the new URL, as applicable.

On which market are KZIA ADSs listed and what was the recent price?

Kazia Therapeutics’ ADSs are listed on the Nasdaq Capital Market under the symbol KZIA. On August 28, 2026, the last reported sale price of the ADSs was $13.58 per ADS.

Which other Kazia Therapeutics registration statements incorporate this Form 6-K by reference?

The Form 6-K incorporated into the KZIA prospectus supplement is also incorporated by reference into Kazia’s Form F-3 registration statements with File Nos. 333-276091, 333-281937 and 333-294392.

Does the KZIA prospectus supplement change the risk factors for investors?

The supplement directs investors to the existing “Risk Factors” in the prospectus and in Kazia’s most recent Form 20-F and other filings. It does not introduce new risk factor language in this document, but maintains the high-risk investment characterization.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 08/31/2026 - 07:33 AM Accepted by SEC EDGAR 08/31/2026 - 07:32 AM Learn about SEC filing dates

Filed Pursuant to Rule 424(b)(3)
Registration No. 333-284606

PROSPECTUS SUPPLEMENT

(to Prospectus dated December 22, 2025)

266,666 American Depositary Shares representing

133,333,000

Ordinary Shares

Kazia Therapeutics Limited

This prospectus supplement is being filed to update and supplement the information contained in the prospectus dated December 22, 2025 (the “Prospectus”), which forms a part of our Registration Statement on Form F-1 (Registration No. 333-284606), as amended, with the information contained in our current report on Form 6-K, furnished to the Securities and Exchange Commission on August 31, 2026 (the “August 31, 2026 Form 6-K”). Accordingly, we have attached the August 31, 2026 Form 6-K to this prospectus supplement.

This prospectus supplement updates and supplements the information in the Prospectus and is not complete without, and may not be delivered or utilized except in combination with, the Prospectus, including any amendments or supplements thereto. This prospectus supplement should be read in conjunction with the Prospectus and if there is any inconsistency between the information in the Prospectus and this prospectus supplement, you should rely on the information in this prospectus supplement.

The ADSs are listed on The Nasdaq Capital Market (“Nasdaq”) under the symbol “KZIA.” On August 28, 2026, the last reported sale price of the ADSs on Nasdaq was $13.58 per ADS.

Investing in our securities involves a high degree of risk. See “Risk Factors” beginning on page 9 of the Prospectus and the “Risk Factors” in “Item 3. Key Information-D. Risk Factors” of our most recent Annual Report on Form 20-F, which is incorporated by reference in the Prospectus, as well as in any other recently filed reports and, if any, in any applicable prospectus supplement.

Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or passed upon the adequacy or accuracy of the Prospectus or this prospectus supplement. Any representation to the contrary is a criminal offense.

The date of this prospectus supplement is August 31, 2026

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 6-K

REPORT OF FOREIGN PRIVATE ISSUER

PURSUANT TO RULE 13a-16 OR 15d-16

UNDER THE SECURITIES EXCHANGE ACT OF 1934

For the month of August 2026

Commission File Number: 000-29962

Kazia Therapeutics Limited.

(Exact Name of Registrant as Specified in Its Charter)

Three International Towers Level 24 300 Barangaroo Avenue Sydney NSW 2000

(Address of principal executive offices)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

Form 20-F ☒        Form 40-F ☐

INFORMATION CONTAINED IN THIS FORM 6-K REPORT

On August 28, 2026, Kazia Therapeutics Limited (the “Company”) launched a new website. The new website can be found at www.kaziatx.com.

Any prior references to the Company’s website, including references to www.kaziatherapeutics.com, in the Company’s filings with the Securities Exchange Commission (the “SEC”) should be read to refer to the new URL, www.kaziatx.com, as applicable.

The new website has been designed to provide investors, customers, and other stakeholders with enhanced access to information regarding the Company’s business, products, services, clinical trials, and corporate developments. We encourage investors, patients, business partners, researchers, and other stakeholders to review the information we post on our website, in addition to following our press releases and SEC filings.

Incorporation by Reference

The Company hereby incorporates by reference the information contained herein into the Company’s registration statements on Form F-3 (File Nos. 333-276091, 333-281937 and 333-294392).

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SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

	Kazia Therapeutics Limited.
Date: August 31, 2026	By:	/s/ John Friend
	Name:	John Friend
	Title:	Chief Executive Officer

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