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Kazia Therapeutics (KZIA) widens loss yet amasses $69.5m cash and new ATM

Filing Impact
(Neutral)
Filing Sentiment
(Neutral)
Form Type
6-K

Rhea-AI Filing Summary

Kazia Therapeutics Limited reported an unaudited half‑year loss of $12,552,490 for the six months ended 31 December 2025, wider than the prior period’s $10,453,811. Operating cash outflow was $9,540,623, but cash and cash equivalents rose sharply to $69,459,980 as of 31 December 2025 after substantial equity financing.

The company strengthened its balance sheet via private placements, including an approximately $50.0 million equity financing in December 2025 and issuance of pre‑funded warrants, and ended the period with net assets of $46,467,039. R&D focused on paxalisib in breast cancer and glioblastoma, alongside an in‑licensed PD‑L1 degrader program. The auditor’s review raised no independence issues.

Subsequently, Kazia entered a new at‑the‑market equity Sales Agreement with Leerink Partners LLC, allowing periodic sales of American Depositary Shares under an effective Form F‑3 shelf registration, and terminated its prior at‑the‑market program with Rodman & Renshaw LLC.

Positive

  • None.

Negative

  • None.

Insights

Large cash raise offsets ongoing losses, extending runway.

Kazia Therapeutics posted a half‑year loss of $12.55m, driven mainly by $4.99m in research and development and $8.56m in general and administrative expenses. This reflects an R&D‑heavy, pre‑revenue biotech profile.

Despite negative operating cash flow of $9.54m, the company’s cash balance climbed to $69.46m after raising $75.32m from financing activities, including a roughly $50.0m private placement and pre‑funded warrants. Net assets improved to $46.47m from a prior deficit.

The new at‑the‑market program with Leerink Partners provides additional flexibility to issue ADSs over time under the Form F‑3 shelf, replacing the prior Rodman arrangement. Actual dilution and capital inflows will depend on future usage disclosed in subsequent filings.

 

 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION 

WASHINGTON, D.C. 20549

 

FORM 6-K

 

REPORT OF FOREIGN PRIVATE ISSUER
PURSUANT TO RULE 13a-16 OR 15d-16
UNDER THE SECURITIES EXCHANGE ACT OF 1934

 

For the Month of March 2026

 

Commission File Number: 000-29962

 

Kazia Therapeutics Limited. 

(Exact Name of Registrant as Specified in Its Charter)

 

Three International Towers Level 24 300 Barangaroo Avenue Sydney NSW 2000

(Address of principal executive offices)

 

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

 

Form 20-F ☒      Form 40-F ☐

 

 

 

 

 

 

INFORMATION CONTAINED IN THIS FORM 6-K REPORT

 

Entry into Sales Agreement

 

On March 17, 2026, Kazia Therapeutics Limited., an Australian public company limited by shares (the “Company”) entered into a sales agreement (the “Sales Agreement”) with Leerink Partners LLC (“Leerink Partners”), pursuant to which the Company may issue and sell, from time to time, American Depositary Shares (the “ADSs”), each representing five hundred (500) fully paid ordinary shares of the Company, no par value per share (the “Ordinary Shares”), through or to Leerink Partners, acting as agent or principal. In connection with entering into the Sales Agreement, the Company terminated the at-the-market offering agreement, dated July 25, 2025, by and among the Company and Rodman & Renshaw LLC related to its prior at-the-market offering.

 

Subject to the terms and conditions of the Sales Agreement, Leerink Partners will use its commercially reasonable efforts consistent with its normal trading and sales practices to place all of the ADSs requested to be sold by the Company. The Company will pay Leerink Partners a commission rate equal to 3.0% of the gross proceeds from the sale of ADSs sold pursuant to the Sales Agreement. The Company has provided Leerink Partners with customary representations, warranties, covenants, and indemnification rights.

 

Sales of the ADSs under the Sales Agreement may be made by any method permitted by law deemed to be an “at the market offering” as defined in Rule 415 of the Securities Act Regulations.

 

The ADSs will be offered and sold pursuant to the Company’s Registration Statement on Form F-3 (File No. 333-294392) (the “Registration Statement”), which was originally filed with the Securities and Exchange Commission (“SEC”) on March 18, 2026, the base prospectus contained within the Registration Statement, and a prospectus supplement that was filed with the SEC on March 18, 2026 in connection with the offer and sale of the ADSs pursuant to the Sales Agreement (the “Prospectus Supplement”). The ADSs may only be offered and sold by means of a prospectus, including a prospectus supplement, forming part of the effective Registration Statement.

 

The foregoing description of the Sales Agreement is not complete and is qualified in its entirety by reference to the full text of the Sales Agreement, which is filed as Exhibit 1.1 to the Company’s Registration Statement on Form F-3 (File No. 333-294392).

 

This Current Report on Form 6-K shall not constitute an offer to sell or the solicitation of an offer to buy nor shall there be any sale of the Shares or the ADSs in any state in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state.

 

Incorporation by Reference

 

The Company hereby incorporates by reference the information contained in the body of this Report on Form 6-K and Exhibit 99.1 hereto into the registration statement on Form F-3 of Kazia Therapeutics Limited.(File No. 333-294392) (including any prospectuses forming a part of such registration statement) and shall be a part thereof from the date on which this current report is furnished, to the extent not superseded by documents or reports subsequently filed or furnished.

 

On March 16, 2026 AEDT, Kazia Therapeutics Limited (the “Company”) reported its unaudited half-year results for the six months ended December 31, 2025, a copy of which is attached to this Form 6-K as Exhibit 99.1.

 

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EXHIBIT LIST

 

Exhibit   Description
     
99.1   Half-year report for the six months ended December 31, 2025
     
101.INS   XBRL Instance Document
   
101.SCH   XBRL Taxonomy Extension Schema Document
   
101.CAL   XBRL Taxonomy Extension Calculation Linkbase Document
   
101.DEF   XBRL Taxonomy Extension Definition Linkbase Document
   
101.LAB   XBRL Taxonomy Extension Label Linkbase Document
   
101.PRE   XBRL Taxonomy Extension Presentation Linkbase Document
   
104   Cover Page Interactive Data File (embedded within the Inline XBRL document)

 

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SIGNATURES

 

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

 

  Kazia Therapeutics Limited.
     
  By: /s/ John Friend
  Name:  John Friend
  Title: Chief Executive Officer
     
Date: March 30, 2026    

 

3

 

Exhibit 99.1

 

 

Kazia Therapeutics Limited

ABN 37 063 259 754

Half Yearly Report - 31 December 2025

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Kazia Therapeutics Limited
Directors’ report
31 December 2025

 

The directors present their report, together with the financial statements, on the Consolidated entity (referred to hereafter as the ‘Consolidated entity’) consisting of Kazia Therapeutics Limited (referred to hereafter as the ‘Consolidated entity’ or ‘parent entity’) and the entities it controlled at the end of, or during, the half-year ended 31 December 2025.

 

Directors

 

The following persons were directors of Kazia Therapeutics Limited during the whole of the financial year and up to the date of this report, unless otherwise stated:

 

Dr John Friend

Bryce Carmine

Steven Coffey

Ebru Davidson

Robert Apple

 

Principal activities

 

During the financial year the principal continuing activity of the Consolidated entity consisted of pharmaceutical research and development with a view to commercialising the results of our research through license transactions or other means.

 

Review of operations

 

The loss for the Consolidated entity after providing for income tax amounted to $12,552,490 (31 December 2024: $10,453,811).

 

The attached financial statements detail the performance and financial position of the Consolidated entity for the half-year ended 31 December 2025.

 

Cash resources

 

At 31 December 2025, the Consolidated entity had total funds of $69,459,980 comprising cash in hand and at bank.

 

Going concern

 

For the period ended 31 December 2025 the Consolidated Entity incurred a loss after income tax of $12,552,490 (31 December 2024: $10,453,811), was in a net current asset position of $45,612,689 (30 June 2025 net current liability: $9,119,727) and had net cash outflows from operating activities of $9,540,623 (31 December 2024: $8,420,244) for the half-year ended 31 December 2025.

 

The Directors note the following with regards to the ability of the Consolidated Entity to continue as a going concern:

 

During the period, the Company received notifications from Nasdaq regarding non-compliance with the minimum Market Value of Listed Securities requirement. On 18 December 2025, the Nasdaq Office of General Counsel confirmed that the Company had regained compliance with Listing Rule 5550(b) and remained in compliance with all applicable listing standards. Accordingly, the Company’s ADSs continue to trade on The Nasdaq Capital Market.

 

The Consolidated Entity continued to access capital markets during the period. Capital raised in the period, including the PIPE entered on 2nd December 2025 which raised US$46.51 million after deducting offering expenses has resulted in a cash balance of AUD 69.46 million at 31 December 2025. The Directors have considered the Consolidated Entity’s cash flow forecasts for a period of at least 12 months from the date of this report, together with available cash and capital-raising mechanisms, and believe that the Group will be able to meet its obligations as and when they fall due.

 

Accordingly, the financial statements have been prepared on a going concern basis which assumes continuity of normal activities and the realisation of assets and the settlement of liabilities in the ordinary course of business.

 

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Kazia Therapeutics Limited
Directors’ report
31 December 2025

 

Research and development report

 

During the reporting period (July 1, 2025 to December 31, 2025), the Consolidated entity advanced paxalisib beyond neuro-oncology into multiple breast cancer translational and clinical settings, including a Company-sponsored Phase 1b study in metastatic triple-negative breast cancer (TNBC), collaborative ex vivo studies in HER2-positive metastatic breast cancer, and expanded-access real-world use. On 10 July 2025, the Company reported preliminary results from the first patient in its Phase 1b paxalisib combination regimen (paxalisib + pembrolizumab + standard chemotherapy) after 21 days of dosing, including a >50% reduction in circulating tumor cells (CTCs) and a notable decrease in CTC clusters.

 

On 1 August 2025, the Company announced an approximately $2.0 million private placement at a premium to market, with proceeds intended to support continued clinical development of the company’s lead programs, including paxalisib and EVT801.

 

On 11 September 2025, the Company announced new findings from a collaborative research program led by Professor Sudha Rao at QIMR Berghofer, reporting that paxalisib monotherapy demonstrated a statistically significant reduction in single CTCs and complete (100%) disruption of CTC clusters (>3 cells) in ex vivo blood samples from stage IV HER2-positive metastatic breast cancer patients.

 

On 2 October 2025, the Company reported an expanded-access case in metastatic TNBC treated with a combination immunotherapy/chemotherapy regimen plus paxalisib, in which imaging after three weeks of treatment demonstrated an 86% reduction in overall tumor burden.

 

In October 2025, the Company also expanded its immuno-oncology pipeline through an exclusive collaboration and in-licensing agreement with QIMR Berghofer for a first-in-class PD-L1 protein degrader program (lead optimized compound NDL2), intended to address resistance mechanisms not reached by existing checkpoint inhibitors.

 

On 27 October 2025, the Company announced its intention to request a follow-up FDA Type C meeting to discuss overall survival findings in newly diagnosed glioblastoma patients treated with paxalisib and to seek feedback on a potential regulatory pathway aligned with the FDA Oncology Center of Excellence’s Project FrontRunner initiative.

 

On 18 November 2025, the Company provided a clinical update describing an initial immune-complete response (iCR) in metastatic TNBC in an expanded-access setting and a broader Q4 business update across breast cancer immuno-oncology and GBM regulatory strategy.

 

In December 2025, the Company reported additional momentum across both R&D execution and corporate runway. On 2 December 2025, the Company announced the pricing of an approximately $50.0 million private placement of equity securities, with expected net proceeds of approximately $46.5 million after fees and expenses, intended to support continued clinical development programs. On 10 December 2025, the Company announced new data from two presentations at the 2025 San Antonio Breast Cancer Symposium (SABCS), describing mechanistic and early clinical evidence supporting paxalisib activity across HER2-positive metastatic breast cancer and TNBC.

 

Significant changes in the state of affairs

 

As noted in the ’Going concern’ section of this Directors report, the Company entered into two securities purchase agreement with certain established institutional investors for a private placement of equity securities (PIPE).

 

Apart from this change, there were no other significant changes in the state of affairs of the Consolidated entity during the financial half-year.

 

Matters subsequent to the end of the financial half-year

 

No matter or circumstance has arisen since 31 December 2025 that has significantly affected, or may significantly affect the Consolidated entity’s operations, the results of those operations, or the Consolidated entity’s state of affairs in future financial years.

 

Auditors independence declaration

 

A copy of the auditors independence declaration as required under section 307C of the Corporations Act 2001 is set out immediately after this directors report.

 

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Kazia Therapeutics Limited
Directors’ report
31 December 2025

 

This report is made in accordance with a resolution of Directors, pursuant to section 298(2)(a) of the Corporations Act 2001.

 

On behalf of the Directors

 

/s/ Steven Coffey  
Steven Coffey  
Director  
   
16 March 2026  
Sydney  

 

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Tel: +61 2 9251 4100
Fax: +61 2 9240 9821
www.bdo.com.au
Parkline Place
Level 25, 252 Pitt Street
Sydney NSW 2000 Australia

 

DECLARATION OF INDEPENDENCE BY GARETH FEW TO THE DIRECTORS OF KAZIA THERAPEUTICS LIMITED

 

As lead auditor for the review of Kazia Therapeutics Limited for the half-year ended 31 December 2025, I declare that, to the best of my knowledge and belief, there have been:

 

1. No contraventions of the auditor independence requirements of the Corporations Act 2001 in relation to the review; and

 

2. No contraventions of any applicable code of professional conduct in relation to the review.

 

This declaration is in respect of Kazia Therapeutics Limited and the entities it controlled during the period.

 

 

/s/ Gareth Few  
Gareth Few  
Director  
   
BDO Audit Pty Ltd  
   
Sydney, 16 March 2026  

 

BDO Audit Pty Ltd ABN 33 134 022 870 is a member of a national association of independent entities which are all members of BDO International Ltd, a UK company limited by guarantee, and form part of the international BDO network of independent member firms. Liability limited by a scheme approved under Professional Standards Legislation.

 

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Kazia Therapeutics Limited
Contents
31 December 2025

 

Statement of profit or loss and other comprehensive income   6
Statement of financial position   7
Statement of changes in equity   8
Statement of cash flows   9
Notes to the financial statements   10
Directors’ declaration   19
Independent auditor’s review report to the members of Kazia Therapeutics Limited   20

 

General information

 

The financial statements cover Kazia Therapeutics Limited as a Consolidated entity consisting of Kazia Therapeutics Limited and the entities it controlled at the end of, or during, the half-year. The financial statements are presented in Australian dollars, which is Kazia Therapeutics Limited’s functional and presentation currency.

 

Kazia Therapeutics Limited is a public Consolidated entity limited by shares, incorporated and domiciled in Australia. Its registered office and principal place of business is:

 

Three International Towers

Level 24, 300 Barangaroo Avenue

Sydney NSW 2000

 

A description of the nature of the Consolidated entity’s operations and its principal activities are included in the directors report, which is not part of the financial statements.

 

The financial statements were authorised for issue, in accordance with a resolution of directors, on 16 March 2026.

 

5

 

 

Kazia Therapeutics Limited
Statement of profit or loss and other comprehensive income
For the half-year ended 31 December 2025

 

       Consolidated 
   Note   December 2025
$
   December 2024
$
 
Revenue and other income            
Other income        91,921    22,290 
Finance Income        160,923    28,667 
Expenses               
Research and development expense        (4,992,238)   (4,282,101)
General and administrative expense   3    (8,558,016)   (5,108,573)
Fair value gain/(loss) on financial liabilities        744,920    (1,999,648)
Gain on revaluation of contingent consideration        -    750,008 
                
Loss before income tax benefit        (12,552,490)   (10,589,357)
Income tax benefit        -    135,546 
Loss after income tax benefit for the half-year attributable to the owners of Kazia Therapeutics Limited        (12,552,490)   (10,453,811)
Other comprehensive (loss) / income               
Items that may be reclassified subsequently to profit or loss               
Net exchange difference on translation of financial statements of foreign controlled entities, net of tax        (859,893)   174,335 
Other comprehensive (loss) / income for the half-year, net of tax        (859,893)   174,335 
                
Total comprehensive loss for the half-year attributable to the owners of Kazia Therapeutics Limited        (13,412,383)   (10,279,476)
                
         Cents    Cents 
Basic loss per share   17    (0.805)   (2.459)
Diluted loss per share   17    (0.805)   (2.459)

 

The above statement of profit or loss and other comprehensive income should be read in conjunction with the accompanying notes

 

6

 

 

Kazia Therapeutics Limited
Statement of financial position
As at 31 December 2025

 

       Consolidated 
   Note   December 2025
$
   June
2025
$
 
Assets            
Current assets            
Cash and cash equivalents   4    69,459,980    4,344,691 
Trade and other receivables   5    315,539    97,911 
Other assets   6    210,498    490,558 
Total current assets        69,986,017    4,933,160 
Non-current assets               
Trade and other receivables   5    40,000    40,000 
Intangibles   7    1,086,516    1,086,516 
Total non-current assets        1,126,516    1,126,516 
Total assets        71,112,533    6,059,676 
Liabilities               
Current liabilities               
Trade and other payables   8    9,648,456    10,116,769 
Other financial liabilities   9    14,180,627    3,150,301 
Borrowings   10    98,807    395,640 
Employee benefits provision   11    445,438    390,177 
Total current liabilities        24,373,328    14,052,887 
Non-current liabilities               
Deferred tax liability   12    271,629    271,629 
Employee benefits provision   11    537    36,609 
Total non-current liabilities        272,166    308,238 
Total liabilities        24,645,494    14,361,125 
Net assets/(liabilities)        46,467,039    (8,301,449)
Equity               
Contributed equity   13    186,592,055    123,045,889 
Other contributed equity   14    380,224    380,224 
Reserves   15    5,104,456    3,099,687 
Accumulated losses        (145,609,696)   (134,827,249)
Total equity/(deficiency)        46,467,039    (8,301,449)

 

The above statement of financial position should be read in conjunction with the accompanying notes

 

 

7

 

 

Kazia Therapeutics Limited
Statement of changes in equity
For the half-year ended 31 December 2025

 

Consolidated   Contributed
equity
$
    Other
contributed
equity
$
    Share based
payment
reserve
$
    Foreign
currency
translation
reserve
$
    Accumulated
losses
$
    Total deficit
$
 
Balance at 1 July 2024     101,637,758       -       4,224,946       (750,191 )     (115,130,270 )     (10,017,757 )
Loss after income tax benefit for the half-year     -       -       -       -       (10,453,811 )     (10,453,811 )
Other comprehensive income for the half-year, net of tax     -       -       -       174,335       -       174,335  
Total comprehensive income for the half-year     -       -       -       174,335       (10,453,811 )     (10,279,476 )
Issue of shares     16,387,602       -       -       -       -       16,387,602  
Transactions with owners in their capacity as owners:                                                
Share issue costs     (187,965 )     -       -       -       -       (187,965 )
Unissued equity     (380,224 )     380,224       -       -       -       -  
Employee share-based payment options - expired     -       -       (495,900 )     -       495,900       -  
Employee share-based payment options     -       -       290,053       -       -       290,053  
Balance at 31 December 2024     117,457,171       380,224       4,019,099       (575,856 )     (125,088,181 )     (3,807,543 )

 

Consolidated   Contributed
equity
$
    Other
contributed
equity
$
    Share based
payment
reserve
$
    Foreign
currency
translation
reserve
$
    Accumulated
losses
$
    Total equity
$
 
Balance at 1 July 2025     123,045,889       380,224       3,873,198       (773,511 )     (134,827,249 )     (8,301,449 )
Loss after income tax expense for the half-year     -       -       -       -       (12,552,490 )     (12,552,490 )
Other comprehensive loss for the half-year, net of tax     -       -       -       (859,893 )             (859,893 )
Total comprehensive loss for the half-year     -       -       -       (859,893 )     (12,552,490 )     (13,412,383 )
Transactions with owners in their capacity as owners:                                                
Issue of shares     65,248,181       -       -       -       -       65,248,181  
Share issue costs     (1,702,015 )     -       -       -       -       (1,702,015 )
Employee share-based payment options - expired     -       -       (1,770,043 )     -       1,770,043       -  
Employee share-based payment options     -       -       4,634,705       -       -       4,634,705  
Balance at 31 December 2025     186,592,055       380,224       6,737,860       (1,633,404 )     (145,609,696 )     46,467,039  

 

The above statement of changes in equity should be read in conjunction with the accompanying notes

 

8

 

 

Kazia Therapeutics Limited
Statement of cash flows
For the half-year ended 31 December 2025

 

       Consolidated 
   Note   December
2025
$
   December
2024
$
 
Cash flows from operating activities            
Other Income        91,921    - 
Payments to suppliers (inclusive of GST)        (9,793,467)   (8,420,244)
         (9,701,546)   (8,420,244)
Interest received        160,923    - 
Net cash used in operating activities   18    (9,540,623)   (8,420,244)
Cash flows from financing activities               
Proceeds from issue of shares (net of costs)   13    53,735,958    8,561,589 
Proceeds from issue of pre-funded warrants   9    21,585,452    1,178,106 
Net cash from financing activities        75,321,410    9,739,695 
Net increase in cash and cash equivalents        65,780,787    1,319,451 
Cash and cash equivalents at the beginning of the financial half-year        4,344,691    1,657,478 
Effects of exchange rate changes on cash and cash equivalents        (665,498)   87,379 
Cash and cash equivalents at the end of the financial half-year   4    69,459,980    3,064,308 

 

The above statement of cash flows should be read in conjunction with the accompanying notes

 

9

 

 

Kazia Therapeutics Limited
Notes to the financial statements
31 December 2025

 

Note 1. Material accounting policy information

 

These general purpose financial statements for the interim half-year reporting period ended 31 December 2025 have been prepared in accordance with Australian Accounting Standard AASB 134 Interim Financial Reporting and the Corporations Act 2001, as appropriate for for-profit oriented entities. Compliance with AASB 134 ensures compliance with International Financial Reporting Standard IAS 34 Interim Financial Reporting.

 

These general purpose financial statements do not include all the notes of the type normally included in annual financial statements. Accordingly, these financial statements are to be read in conjunction with the annual report for the year ended 30 June 2025 and any public announcements made by the Consolidated entity during the interim reporting period in accordance with the continuous disclosure requirements of the Corporations Act 2001.

 

The accounting policies adopted are consistent with those of the previous financial year and corresponding interim reporting period, unless otherwise stated.

 

Classification and initial measurement of financial assets

 

The Consolidated entity’s other financial liabilities comprise derivatives in respect of prefunded and ordinary warrants. Prefunded and ordinary warrants are measured at fair value through profit or loss. All transactions costs in relation to the warrants are expensed immediately. Changes to the fair value of the instruments post issue will be recognised in profit or loss.

 

New or amended Accounting Standards and Interpretations adopted

 

The Consolidated entity has adopted all of the new, revised or amending Accounting Standards and Interpretations issued by the Australian Accounting Standards Board (AASB) that are mandatory for the current reporting period. Any new, revised or amending Accounting Standards or Interpretations that are not yet mandatory have not been early adopted. The adoption of these Accounting Standards and Interpretations did not have any significant impact on the financial performance or position of the Consolidated entity.

 

Going concern

 

For the period ended 31 December 2025 the Consolidated Entity incurred a loss after income tax of $12,552,490 (31 December 2024: $10,453,811), was in a net current asset position of $45,612,689 (30 June 2025 net current liability: $9,119,727) and had net cash outflows from operating activities of $9,540,623 (31 December 2024: $8,420,244) for the half-year ended 31 December 2025.

 

The Directors note the following with regards to the ability of the Consolidated Entity to continue as a going concern:

 

During the period, the Company received notifications from Nasdaq regarding non-compliance with the minimum Market Value of Listed Securities requirement. On 18 December 2025, the Nasdaq Office of General Counsel confirmed that the Company had regained compliance with Listing Rule 5550(b) and remained in compliance with all applicable listing standards. Accordingly, the Company’s ADSs continue to trade on The Nasdaq Capital Market.

 

The Consolidated Entity continued to access capital markets during the period. Capital raised in the period, including the PIPE entered on 2nd December 2025 which raised US$46.51 million after deducting offering expenses has resulted in a cash balance of AUD 69.46 million at 31 December 2025. The Directors have considered the Consolidated Entity’s cash flow forecasts for a period of at least 12 months from the date of this report, together with available cash and capital-raising mechanisms, and believe that the Group will be able to meet its obligations as and when they fall due.

 

Accordingly, the financial statements have been prepared on a going concern basis which assumes continuity of normal activities and the realisation of assets and the settlement of liabilities in the ordinary course of business.

 

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Kazia Therapeutics Limited
Notes to the financial statements
31 December 2025

 

Note 2. Critical accounting judgements, estimates and assumptions

 

When preparing the half-year financial statements, management undertakes a number of judgements, estimates and assumptions about recognition and measurement of assets, liabilities, income and expenses. The actual results may differ from the judgements, estimates and assumptions made by management and will seldom equal the estimated results.

 

The judgments, estimates and assumptions applied in the half-year financial statements, including key sources of estimation uncertainty were the same as those applied in the Consolidated entity’s last annual financial statements for the year ended 30 June 2025.

 

Note 3. Expenses

 

   Consolidated 
   December
2025
$
   December
2024
$
 
Loss before income tax includes the following specific expenses:        
Amortisation        
Amortisation   -     934,710 
Interest expense          
Borrowings   7,263    10,033 
Contingent consideration - Effective interest   -     223,035 
    7,263    233,068 
Superannuation expense          
Defined contribution superannuation expense   27,900    26,738 
Employee benefits expense excluding superannuation          
Employee benefits expense excluding superannuation   1,381,820    1,138,052 
Share based payment expense          
Share based payment expense   4,634,705    290,053 

 

Note 4. Cash and cash equivalents

 

   Consolidated 
   December
2025
$
   June 2025
$
 
Current assets        
Cash at bank and on hand   69,459,980    4,344,691 

 

11

 

 

Kazia Therapeutics Limited
Notes to the financial statements
31 December 2025

 

Note 5. Trade and other receivables

 

   Consolidated 
   December
2025
$
   June
2025
$
 
Current assets        
Deposits held   7,687    7,687 
BAS receivable   307,852    90,224 
    315,539    97,911 
Non-current assets          
Corporate credit card deposit   40,000    40,000 
    355,539    137,911 

 

Note 6. Other assets

 

   Consolidated 
   December
2025
$
   June
2025
$
 
Current assets        
Prepayments   210,498    490,558 

 

Other assets contain the prepayment of invoices in relation to the annual insurance renewal program and an offsetting borrowing for the funding of this prepayment in included in Borrowings - See Note 10 ‘Borrowings’.

 

Note 7. Intangibles

 

   Consolidated 
   December
2025
$
   June
2025
$
 
Non-current assets        
Licensing agreement - Paxalisib   1,086,516    1,086,516 

 

Reconciliations

 

Reconciliations of the written down values at the beginning and end of the current financial half-year are set out below:

 

Balance at 1 July 2025   1,086,516    1,086,516 
Balance at 31 December 2025   1,086,516    1,086,516 

 

12

 

 

Kazia Therapeutics Limited
Notes to the financial statements
31 December 2025

 

Note 8. Trade and other payables

 

   Consolidated 
   December
2025
$
   June
2025
$
 
Current liabilities        
Trade payables   6,127,338    5,644,797 
Accrued and other payables   3,521,118    4,471,972 
    9,648,456    10,116,769 

 

Note 9. Other financial liabilities

 

   Consolidated 
   December
2025
$
   June
2025
$
 
Current liabilities        
Prefunded and ordinary warrants   14,180,627    3,150,301 

 

Reconciliation

 

Reconciliation of the written down values at the beginning and end of the current and previous financial year end are set out below:

 

Opening balance   3,150,301    6,478,060 
Prefunded and ordinary warrants at initial recognition   21,585,452    3,034,625 
Prefunded warrants exercised   (9,810,204)   (8,840,101)
Gain / Loss on remeasurement of other financial liabilities   (744,920)   2,477,717 
Closing balance   14,180,627    3,150,301 

 

On 25 July 2025 Maxim Partners LLC exercised a net settlement of warrants and was issued 1,057,000 ordinary shares.

 

On 31 July 2025 the Consolidated Entity entered into a securities purchase agreement with certain established institutional investors for a private placement of equity securities (PIPE). The net proceeds from the PIPE were US$2,049,992, after deducting offering expenses. Pursuant to the Purchase Agreement, the Consolidated Entity agreed to offer and sell in the Private Placement to such Purchasers (i) 14,204,500 ordinary shares at a purchase price of $0.0176 per Share, and (ii) pre-funded warrants to purchase up to 204,547 American Depositary Shares (“ADSs”), each ADS representing five hundred Ordinary Shares, at a purchase price of $8.7999 per Pre-Funded Warrant. Each Pre-Funded Warrant is exercisable for one ADS at an exercise price of $0.0001 and are exercisable immediately and will expire when exercised in full. The pre-funded Warrants were determined to be classified as a financial liability and a derivative under AASB 132 “Financial Instruments: Presentation” accounted for at fair value through profit and loss because they are denominated in a foreign currency, causing the value to vary with the USD/AUD exchange rate and the Consolidated Entity’s share price, requires a smaller net investment, and is settled at a future date. The initial fair value of the pre-funded Warrants was A$2,600,115.

 

13

 

 

Kazia Therapeutics Limited
Notes to the financial statements
31 December 2025

 

Note 9. Other financial liabilities (continued)

 

On 2 December 2025 the Consolidated Entity entered into a securities purchase agreement with certain established institutional investors for a private placement of equity securities (PIPE). The net proceeds from the PIPE were US$46,509,833, after deducting offering expenses. Pursuant to the Purchase Agreement, the Consolidated Entity agreed to offer and sell in the Private Placement to such Purchasers (i) 4,530,854,000 ordinary shares at a purchase price of $0.01 per Share, and (ii) pre-funded warrants to purchase up to 938,490 American Depositary Shares (“ADSs”), each ADS representing five hundred Ordinary Shares, at a purchase price of $4.9999 per Pre-Funded Warrant. Each Pre-Funded Warrant is exercisable for one ADS at an exercise price of $0.0001 and are exercisable immediately and will expire when exercised in full. The pre-funded Warrants were determined to be classified as a financial liability and a derivative under AASB 132 “Financial Instruments: Presentation” accounted for at fair value through profit and loss because they are denominated in a foreign currency, causing the value to vary with the USD/AUD exchange rate and the Consolidated Entity’s share price, requires a smaller net investment, and is settled at a future date. The initial fair value of the pre-funded Warrants was A$18,985,338. Transaction costs of A$5,278,293 were incurred and allocated on a pro rata basis between the equity and derivative liability components with the portion allocated to the derivative liability component expensed immediately.

 

On 10 December 2025 Alumni Capital LP exercised a net settlement of warrants and was issued 219,841,000 ordinary shares.

 

Note 10. Borrowings

 

   Consolidated 
   December
2025
$
   June
2025
$
 
Current liabilities        
Insurance premium funding   98,807    395,640 

 

Borrowings relate to the annual insurance renewal program. An offsetting prepayment of insurance invoices is included in Prepayments - See Note 6 ‘Other assets’.

 

Note 11. Employee benefits

 

   Consolidated 
   December
2025
$
   June
2025
$
 
Current liabilities        
Annual leave   405,833    390,177 
Long service leave   39,605    -  
    445,438    390,177 
Non-current liabilities          
Long service leave   537    36,609 
    445,975    426,786 

 

14

 

 

Kazia Therapeutics Limited
Notes to the financial statements
31 December 2025

 

Note 12. Deferred tax liability

 

   Consolidated 
   December
2025
$
   June
2025
$
 
Non-current liabilities        
Deferred tax liability associated with Licencing Agreement   271,629    271,629 

 

The Company has completed an analysis of the availability of historical tax losses to offset the deferred tax liability, concluding that the historical tax losses are not expected to be available for offset against the deferred tax liability.

 

Note 13. Contributed equity

 

    Consolidated  
  December
2025
Shares
    June
2025
Shares
    December
2025
$
    June
2025
$
 
 
 
Ordinary shares - fully paid     5,667,995,734       809,418,734       186,592,055       123,045,889  

 

Movements in share capital

 

Details  Date  Shares   Issue
price
   $ 
Balance  1 July 2025   809,418,734         123,045,889 
Maxim Warrants Net Settlement  25 July 2025   1,057,000   $0.0882    93,280 
August PIPE  5 August 2025   14,204,500   $0.0412    585,576 
ATM issue of shares No. 65  20 August 2025   650,000   $0.0229    14,869 
ATM issue of shares No. 66  27 August 2025   1,382,500   $0.0255    35,243 
ATM issue of shares No. 67  12 September 2025   8,576,000   $0.0255    219,008 
ATM issue of shares No. 68  3 October 2025   82,012,000   $0.0234    1,922,778 
December PIPE - (Net of transaction costs)  3 December 2025   4,530,854,000   $0.0116    52,660,499 
Alumni Warrants Net Settlement  10 December 2025   219,841,000   $0.0442    9,716,928 
Less: share issue transaction costs      -   $0.0000    (1,702,015)
Balance  31 December 2025   5,667,995,734         186,592,055 

 

The at-the-market equity program (“ATM”) allows the Company to raise capital dynamically in the market, which no discount, no warrant coverage, and modest banking fees, allowing it to fund operations with minimal dilution to existing shareholders. An ATM with Oppenheimer & Co. Inc. (Oppenheimer) as sales agent was established in April 2022. Under the ATM, Kazia may offer and sell via Oppenheimer, in the form of American Depository Shares (ADSs), with each ADS representing 500 ordinary shares. Kazia entered into an Equity Distribution Agreement, dated as of 22 April 2022 (the “Sales Agreement”), with Oppenheimer, acting as sales agent for an initial capacity of US$35 million. On 4 September 2024, the Equity Distribution Agreement was amended to increase the aggregate offering price to US$50 million. On 10 July 2025, the Company terminated the ATM with Oppenheimer and on July 25, 2025, Kazia entered into an At the Market Offering Agreement with Rodman & Renshaw LLC (“Rodman”), as sales agent under which the Company may offer and sell, from time to time through Rodman, American Depositary Shares (“ADSs”), each ADS representing five hundred (500) ordinary shares, no par value per share, of the Company (the “Ordinary Shares”).

 

From July through December 2025, the Consolidated entity raised total proceeds, net of expenses of US$1,397,016 using the ATM facility, the remaining capacity of the ATM was US$35.19 million.

 

On 25 July 2025 Maxim Partners LLC exercised a net settlement of warrants and was issued 1,057,000 ordinary shares.

 

On 31 July 2025 the Company entered into a securities purchase agreement with certain established institutional investors for a private placement of equity securities (PIPE). The net proceeds from the PIPE were US$1.80 million, after deducting offering expenses.

 

15

 

 

Kazia Therapeutics Limited
Notes to the financial statements
31 December 2025

 

Note 13. Contributed equity (continued)

 

On 2 December 2025 the Company entered into a securities purchase agreement with certain established institutional investors for a private placement of equity securities (PIPE). The net proceeds from the PIPE were US$46.51 million, after deducting offering expenses.

 

On 10 December 2025 Alumni Capital LP exercised a net settlement of warrants and was issued 219,841,000 ordinary shares.

 

Ordinary shares

 

Ordinary shares entitle the holder to participate in dividends and the proceeds on the winding up of the Consolidated entity in proportion to the number of and amounts paid on the shares held. The fully paid ordinary shares have no par value and the Consolidated entity does not have a limited amount of authorised capital.

 

On a show of hands every member present at a meeting in person or by proxy shall have one vote and upon a poll each share shall have one vote.

 

Share buy-back 

 

There is no current on-market share buy-back. 

 

Capital risk management

 

The Consolidated entity’s objectives when managing capital are to safeguard its ability to continue as a going concern, so that it can provide returns for shareholders and benefits for other stakeholders and to maintain an optimum capital structure to reduce the cost of capital.

 

Capital is regarded as total equity, as recognised in the statement of financial position, plus net debt. Net debt is calculated as total borrowings less cash and cash equivalents.

 

The capital structure of the Consolidated entity consists of cash and cash equivalents and equity attributable to equity holders. The overall strategy of the Consolidated entity is to continue its drug development programs, which depends on raising sufficient funds, through a variety of sources including issuing of additional share capital, as may be required from time to time.

 

The capital risk management policy remains unchanged from the prior year.

 

Note 14. Unissued equity

 

On 23 October 2023, the Company entered into a securities purchase agreement with an accredited investor, pursuant to which the Company issued a six-month unsecured convertible promissory note (the “Note”) in the principal amount of A$776,670 (US$500,000). The Note bears interest at a rate of 10% per annum. On 23 December 2023 the investor called upon 50% of the Note, and cash of US$253,014 was paid, which represented US$250,000 of principal and US$3,014 of interest (total payment of A$380,224). The investor exercised their option to receive the remaining 50% in ADSs on 20 December 2023, which resulted in 591,697 ADS to be issued. On 19 June 2024, 591,697 ADSs representing 5,916,970 ordinary shares were issued at a price of A$0.0643 per ordinary share. Subsequent to 30 June 2024, the investor was unable to meet their obligations for transfer of the shares and on 2 July 2024 the share allocation was cancelled and remains recognised as unissued equity as at 31 December 2025.

 

16

 

 

Kazia Therapeutics Limited
Notes to the financial statements
31 December 2025

 

Note 15. Reserves

 

   Consolidated 
   December
2025
$
   June
2025
$
 
Foreign currency translation reserve   (1,633,404)   (773,511)
Share-based payments reserve   6,737,860    3,873,198 
    5,104,456    3,099,687 

 

Foreign currency reserve

 

The reserve is used to recognise exchange differences arising from translation of the financial statements of foreign operations to Australian dollars.

 

Share-based payments reserve

 

The reserve is used to recognise the value of equity benefits provided to employees and directors as part of their remuneration, and other parties as part of their compensation for services.

 

Share based payments reserve for Employee Share Option Plan

 

During the half year there were no issues under the Employee Share Option Plan

 

Note 16. Dividends

 

There were no dividends paid, recommended or declared during the current or previous financial half-year.

 

Note 17. Loss per share

 

   Consolidated   Consolidated 
   December
2025
$
   December
2024
$
 
Loss after income tax attributable to the owners of Kazia Therapeutics Limited   (12,552,490)   (10,453,811)

 

   Number   Number 
Weighted average number of ordinary shares used in calculating basic loss per share   1,560,213,259    425,157,427 
Weighted average number of ordinary shares used in calculating diluted loss per share   1,560,213,259    425,157,427 

 

   Cents   Cents 
Basic loss per share   (0.805)   (2.459)
Diluted loss per share   (0.805)   (2.459)

 

17

 

 

Kazia Therapeutics Limited
Notes to the financial statements
31 December 2025

 

Note 18. Reconciliation of loss after income tax to net cash used in operating activities

 

   Consolidated 
   December
2025
   December
2024
 
   $   $ 
Loss after income tax benefit for the half-year   (12,552,490)   (10,453,811)
Adjustments for:          
Amortisation   -     934,711 
Share-based payments expense   4,634,705    464,387 
Foreign exchange differences   (194,392)   229,356 
Fair value (gain)/loss on financial liabilities at fair value through profit or loss   (744,920)   1,999,648 
Gain on contingent consideration   -     (750,007)
Contingent consideration interest   -     232,447 
Change in operating assets and liabilities:          
(Increase) / Decrease trade and other receivables   (217,628)   44,560 
Decrease in other assets   280,060    345,311 
Decrease in borrowings   (296,833)   (493,454)
Decrease in trade and other payables   (468,313)   (852,050)
Decrease in deferred tax liabilities   -     (135,546)
Increase in employee benefits provisions   19,188    14,204 
Net cash used in operating activities   (9,540,623)   (8,420,244)

 

Note 19. Events after the reporting period

 

No matter or circumstance has arisen since 31 December 2025 that has significantly affected, or may significantly affect the Consolidated entity’s operations, the results of those operations, or the Consolidated entity’s state of affairs in future financial years.

 

18

 

 

Kazia Therapeutics Limited
Directors’ declaration

31 December 2025

 

In the directors’ opinion:

 

the attached financial statements and notes comply with the Corporations Act 2001, Australian Accounting Standard AASB 134 ‘Interim Financial Reporting’, the Corporations Regulations 2001 and other mandatory professional reporting requirements;

 

the attached financial statements and notes give a true and fair view of the Consolidated entity’s financial position as at 31 December 2025 and of its performance for the financial half-year ended on that date; and

 

there are reasonable grounds to believe that the Consolidated entity will be able to pay its debts as and when they become due and payable.

 

Signed in accordance with a resolution of directors made pursuant to section 303(5)(a) of the Corporations Act 2001.

 

On behalf of the directors

 

/s/ Steven Coffey  
Steven Coffey
Director  
 
   
16 March 2026
Sydney  
 

 

19

 

 

Tel: +61 2 9251 4100
Fax: +61 2 9240 9821
www.bdo.com.au
Parkline Place
Level 25, 252 Pitt Street
Sydney NSW 2000
Australia

 

INDEPENDENT AUDITOR’S REVIEW REPORT

 

To the members of Kazia Therapeutics Limited

 

Report on the Half-Year Financial Report

 

Conclusion

 

We have reviewed the half-year financial report of Kazia Therapeutics Limited (the Company) and its subsidiaries (the Group), which comprises the consolidated statement of financial position as at 31 December 2025, the consolidated statement of profit or loss and other comprehensive income, the consolidated statement of changes in equity and the consolidated statement of cash flows for the half-year ended on that date, material accounting policy information and other explanatory information, and the directors’ declaration.

 

Based on our review, which is not an audit, we have not become aware of any matter that makes us believe that the accompanying half-year financial report of the Group does not comply with the Corporations Act 2001 including:

 

i.Giving a true and fair view of the Group’s financial position as at 31 December 2025 and of its financial performance for the half-year ended on that date; and

 

ii.Complying with Accounting Standard AASB 134 Interim Financial Reporting and the Corporations Regulations 2001.

 

Basis for conclusion

 

We conducted our review in accordance with ASRE 2410 Review of a Financial Report Performed by the Independent Auditor of the Entity. Our responsibilities are further described in the Auditor’s Responsibilities for the Review of the Financial Report section of our report. We are independent of the Group in accordance with the auditor independence requirements of the Corporations Act 2001 and the ethical requirements of the Accounting Professional and Ethical Standards Board’s APES 110 Code of Ethics for Professional Accountants (including Independence Standards) (the Code) that are relevant to the audit of the annual financial report in Australia. We have also fulfilled our other ethical responsibilities in accordance with the Code.

 

We confirm that the independence declaration required by the Corporations Act 2001 which has been given to the directors of the Company, would be the same terms if given to the directors as at the time of this auditor’s review report.

 

Responsibility of the directors for the financial report

 

The directors of the Company are responsible for the preparation of the half-year financial report that gives a true and fair view in accordance with Australian Accounting Standards and the Corporations Act 2001 and for such internal control as the directors determine is necessary to enable the preparation of the half-year financial report that gives a true and fair view and is free from material misstatement, whether due to fraud or error.

 

BDO Audit Pty Ltd ABN 33 134 022 870 is a member of a national association of independent entities which are all members of BDO International Ltd, a UK company limited by guarantee, and form part of the international BDO network of independent member firms. Liability limited by a scheme approved under Professional Standards Legislation.

 

20

 

 

 

 

Auditor’s responsibility for the review of the financial report

 

Our responsibility is to express a conclusion on the half-year financial report based on our review. ASRE 2410 requires us to conclude whether we have become aware of any matter that makes us believe that the half-year financial report is not in accordance with the Corporations Act 2001 including giving a true and fair view of the Group’s financial position as at 31 December 2025 and its financial performance for the half-year ended on that date and complying with Accounting Standard AASB 134 Interim Financial Reporting and the Corporations Regulations 2001. 

 

A review of a half-year financial report consists of making enquiries, primarily of persons responsible for financial and accounting matters, and applying analytical and other review procedures. A review is substantially less in scope than an audit conducted in accordance with Australian Auditing Standards and consequently does not enable us to obtain assurance that we would become aware of all significant matters that might be identified in an audit. Accordingly, we do not express an audit opinion.

 

BDO Audit Pty Ltd  
   
/s/ Gareth Few  
Gareth Few
Director  
 

 

Sydney, 16 March 2026

 

21

 

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FAQ

How much did Kazia Therapeutics (KZIA) lose in the half-year to 31 December 2025?

Kazia reported a half-year loss of $12,552,490 for the six months ended 31 December 2025. This compares with a loss of $10,453,811 in the prior comparable period, reflecting continued investment in research, development, and corporate activities.

What was Kazia Therapeutics (KZIA) cash position at 31 December 2025?

At 31 December 2025, Kazia held $69,459,980 in cash and cash equivalents. This strong cash position followed substantial equity financings during the half-year, providing resources to support ongoing clinical programs and general corporate purposes.

How did Kazia Therapeutics (KZIA) fund its operations during the period?

Kazia funded operations primarily through equity financing, generating $75,321,410 in net cash from financing activities. This included a December 2025 private placement of approximately $50.0 million and proceeds from pre-funded warrants and at-the-market share sales.

What are the key R&D programs highlighted by Kazia Therapeutics (KZIA)?

Kazia advanced paxalisib into multiple breast cancer settings, including metastatic triple-negative disease and HER2-positive ex vivo studies, and continued glioblastoma work. It also in-licensed a first-in-class PD-L1 protein degrader program from QIMR Berghofer to expand its immuno-oncology pipeline.

What new capital raising facility did Kazia Therapeutics (KZIA) establish with Leerink Partners?

Kazia entered a Sales Agreement with Leerink Partners LLC for an at-the-market offering of American Depositary Shares. ADSs will be sold from time to time under the company’s effective Form F-3 shelf, with Leerink earning a 3.0% commission on gross proceeds.

Did the auditor raise any concerns in Kazia Therapeutics (KZIA) half-year review?

The independent auditor’s review concluded without identifying matters causing concern about compliance with the Corporations Act 2001. The auditor also confirmed no contraventions of independence requirements or professional conduct codes during the half-year review.

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Biotechnology
Pharmaceutical Preparations
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