Lixte Biotechnology Hldgs Inc SEC Filings

LIXTW NASDAQ

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06/23/2025 06:23 PM

Filing

[S-1/A] Lixte Biotechnology Holdings, Inc. Warrants Amends IPO Registration Statement

Rhea-AI Summary

Lixte Biotechnology Holdings, Inc. (symbol “LIXT”) filed Amendment No. 1 to its Form S-1 on 23 June 2025, detailing a best-efforts capital raise of up to 7,692,308 shares of common stock and/or an equal number of Pre-Funded Warrants. The assumed offering price is set at the 20 June 2025 Nasdaq closing price of $0.78, implying maximum gross proceeds of roughly $6.0 million if fully subscribed. The company’s common stock trades on the Nasdaq Capital Market; the Pre-Funded Warrants will not be listed and lack an active trading market.

Key terms:

Structure: Investors that would exceed 4.99 % (optionally 9.99 %) ownership may receive Pre-Funded Warrants priced at $0.77999, exercisable immediately until fully exercised, with one-for-one share issuance upon exercise.
Placement Agent: Spartan Capital Securities, LLC will act as sole placement agent on a reasonable best-efforts basis. Compensation includes an 8 % cash fee, a 1 % non-accountable expense allowance, reimbursement of legal expenses up to $125,000, and five-year warrants covering 5 % of the shares sold, exercisable at 125 % of the final offering price.
Timing & Closing: Single closing via DVP/RVP settlement. The offering terminates on 15 July 2025 unless earlier closed or withdrawn. No escrow agent and no minimum raise are required, meaning funds become immediately available to the company regardless of amount raised.
Registration status: The issuer is a non-accelerated, smaller-reporting company. The prospectus remains subject to SEC effectiveness; securities cannot be sold until declared effective.

Investor considerations: The raise could supply working capital but will materially dilute existing shareholders by up to 7.7 million shares (plus placement-agent warrants). Absence of a minimum raise and lack of market for the Pre-Funded Warrants heighten execution and liquidity risks. Prospective investors are directed to the “Risk Factors” section beginning on page 16.

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FAQ

What is the current stock price of Lixte Biotechnology Hldgs (LIXTW)?

The current stock price of Lixte Biotechnology Hldgs (LIXTW) is $0.22 as of July 2, 2025.

What is the core focus of Lixte Biotechnology Holdings Inc?

Lixte Biotechnology Holdings Inc is a clinical-stage company focused on developing innovative protein phosphatase inhibitors for cancer therapy. Its research is aimed at improving the effectiveness of existing oncology treatments.

How does Lixte generate value through its drug development strategy?

The company targets key molecular pathways involved in cell division and DNA repair, designing compounds for use in combination with traditional cytotoxic agents and radiation. This approach aims to enhance cancer treatment efficacy.

What makes Lixte Biotechnology unique in the oncology space?

Lixte is distinctive for its concentrated approach on protein phosphatase inhibition, a niche area in cancer drug development. The integration of its inhibitors with existing therapies positions it uniquely among biopharmaceutical innovators.

What types of therapies are being developed by Lixte?

Lixte is developing therapies that involve protein phosphatase inhibitors to be used in combination with cytotoxic drugs, radiation, and potentially immune checkpoint blockers. These combination treatments are designed to improve overall treatment outcomes.

How does Lixte Biotechnology address safety in its drug development?

The company emphasizes achieving clinical anti-cancer activity at doses that maintain a favorable safety profile. Its research is focused on ensuring that its drug candidates are both effective and tolerable when used in combination with standard therapies.

What is the significance of protein phosphatase 2A inhibitors in Lixte's pipeline?

Protein phosphatase 2A inhibitors are significant because they disrupt processes critical to cell division and DNA damage repair. This disruption can enhance the effects of other cancer treatments, potentially improving patient outcomes.

How does Lixte Biotechnology position itself within the competitive biopharma industry?

Lixte positions itself by focusing on a specialized niche within oncology—protein phosphatase inhibition—thereby offering a differentiated approach. Its strategy of combining these novel agents with conventional therapies sets it apart from competitors.

What role does clinical research play in Lixte's business model?

Clinical research is central to Lixte's business model, providing the foundation for testing the safety and efficacy of its drug candidates. The company collaborates with clinical centers and experts to advance its early-stage assets through rigorous trials.