STOCK TITAN

[Form 4] Lixte Biotechnology Holdings, Inc. Warrants Insider Trading Activity

Filing Impact
(Low)
Filing Sentiment
(Neutral)
Form Type
4
Rhea-AI Filing Summary

Form 4 filing overview: On 06/30/2025, Lixte Biotechnology Holdings (LIXT) director Dr. Yun Yen received two new option grants. The first covers 10,000 shares at an exercise price of $0.905, vesting in eight equal quarterly installments beginning 09/30/2025. The second grant provides 11,632 options at the same price, vesting immediately in lieu of quarterly cash board compensation. Following the grants, Dr. Yen now directly holds a mix of previously issued options dating back to 2018—2025 with strike prices ranging from $0.905 to $66, as well as 5,263 warrants held indirectly through Sino-American Cancer FDD. No common shares were bought or sold, and all transactions involve derivative securities only. The filing indicates continued equity-based alignment between the director and shareholders but does not disclose cash transactions or changes in total share count.

Panoramica della presentazione del Modulo 4: Il 30/06/2025, il direttore di Lixte Biotechnology Holdings (LIXT), Dr. Yun Yen, ha ricevuto due nuove concessioni di opzioni. La prima riguarda 10.000 azioni con un prezzo di esercizio di 0,905 $, che maturano in otto rate trimestrali uguali a partire dal 30/09/2025. La seconda concessione prevede 11.632 opzioni allo stesso prezzo, con maturazione immediata in sostituzione della compensazione trimestrale in contanti del consiglio. Dopo queste concessioni, il Dr. Yen detiene direttamente un mix di opzioni emesse in precedenza dal 2018 al 2025 con prezzi di esercizio che vanno da 0,905 $ a 66 $, oltre a 5.263 warrant detenuti indirettamente tramite Sino-American Cancer FDD. Non sono state acquistate o vendute azioni ordinarie e tutte le transazioni riguardano esclusivamente strumenti derivati. La presentazione indica un continuo allineamento basato su equity tra il direttore e gli azionisti, senza però rivelare transazioni in contanti o variazioni nel numero totale di azioni.

Resumen de la presentación del Formulario 4: El 30/06/2025, el director de Lixte Biotechnology Holdings (LIXT), Dr. Yun Yen, recibió dos nuevas concesiones de opciones. La primera cubre 10.000 acciones con un precio de ejercicio de $0.905, que se consolidan en ocho cuotas trimestrales iguales a partir del 30/09/2025. La segunda concesión otorga 11.632 opciones al mismo precio, con consolidación inmediata en lugar de la compensación trimestral en efectivo del consejo. Tras las concesiones, el Dr. Yen posee directamente una combinación de opciones emitidas previamente desde 2018 hasta 2025 con precios de ejercicio que van desde $0.905 hasta $66, además de 5.263 warrants mantenidos indirectamente a través de Sino-American Cancer FDD. No se compraron ni vendieron acciones comunes, y todas las transacciones involucran únicamente valores derivados. La presentación indica una alineación continua basada en acciones entre el director y los accionistas, pero no revela transacciones en efectivo ni cambios en el número total de acciones.

Form 4 제출 개요: 2025년 6월 30일, Lixte Biotechnology Holdings(LIXT)의 이사 Dr. Yun Yen이 두 건의 새로운 옵션 부여를 받았습니다. 첫 번째는 행사 가격이 $0.90510,000주로, 2025년 9월 30일부터 8번의 동일한 분기별 할부로 베스팅됩니다. 두 번째 부여는 동일한 가격에 11,632 옵션으로, 분기별 현금 이사회 보상 대신 즉시 베스팅됩니다. 이 부여 이후 Dr. Yen은 2018년부터 2025년까지 발행된 다양한 옵션을 직접 보유하고 있으며, 행사가격은 $0.905에서 $66까지 다양합니다. 또한 Sino-American Cancer FDD를 통해 간접적으로 보유한 5,263 워런트도 포함됩니다. 보통주는 매매되지 않았으며, 모든 거래는 파생 증권에만 해당됩니다. 제출 내용은 이사와 주주 간의 지속적인 주식 기반 정렬을 나타내지만, 현금 거래나 총 주식 수의 변동은 공개하지 않습니다.

Présentation du dépôt du formulaire 4 : Le 30/06/2025, le directeur de Lixte Biotechnology Holdings (LIXT), Dr. Yun Yen, a reçu deux nouvelles attributions d'options. La première concerne 10 000 actions à un prix d'exercice de 0,905 $, acquises en huit versements trimestriels égaux à partir du 30/09/2025. La seconde attribution offre 11 632 options au même prix, avec une acquisition immédiate en remplacement de la rémunération trimestrielle en espèces du conseil d'administration. Suite à ces attributions, le Dr Yen détient désormais directement un mélange d'options émises précédemment entre 2018 et 2025, avec des prix d'exercice allant de 0,905 $ à 66 $, ainsi que 5 263 bons de souscription détenus indirectement via Sino-American Cancer FDD. Aucune action ordinaire n'a été achetée ou vendue, toutes les transactions impliquant uniquement des titres dérivés. Le dépôt indique un alignement continu basé sur les actions entre le directeur et les actionnaires, sans divulguer de transactions en espèces ni de changements dans le nombre total d'actions.

Überblick über die Form 4 Einreichung: Am 30.06.2025 erhielt Dr. Yun Yen, Direktor von Lixte Biotechnology Holdings (LIXT), zwei neue Optionszuweisungen. Die erste umfasst 10.000 Aktien zu einem Ausübungspreis von 0,905 $, die in acht gleichen vierteljährlichen Raten ab dem 30.09.2025 vesten. Die zweite Zuweisung beinhaltet 11.632 Optionen zum gleichen Preis, die sofort vesten und anstelle einer vierteljährlichen Barvergütung des Vorstands gewährt werden. Nach den Zuweisungen hält Dr. Yen nun direkt eine Mischung aus zuvor ausgegebenen Optionen von 2018 bis 2025 mit Ausübungspreisen zwischen 0,905 $ und 66 $, sowie 5.263 Warrants, die indirekt über Sino-American Cancer FDD gehalten werden. Es wurden keine Stammaktien gekauft oder verkauft, und alle Transaktionen betreffen ausschließlich derivative Wertpapiere. Die Einreichung zeigt eine fortgesetzte aktienbasierte Ausrichtung zwischen dem Direktor und den Aktionären, gibt jedoch keine Auskunft über Bargeldtransaktionen oder Änderungen der Gesamtzahl der Aktien.

Positive
  • None.
Negative
  • None.

Insights

TL;DR: Routine option grants; modest alignment, limited market impact.

The grant size (≈21.6k options) is relatively small for a micro-cap biotech and replaces cash fees, signaling cash preservation and board-shareholder alignment. Strike price ($0.905) sits near recent trading levels, providing upside incentive without deep discounting. No outright share purchases means limited incremental insider confidence signal. Overall, neutral for valuation and liquidity.

TL;DR: Compensation shifted to equity; governance-friendly, not transformational.

Replacing cash compensation with immediately vested options conserves cash and ties rewards to long-term performance—positive from a governance standpoint. However, immediate vesting dilutes the incentive’s retention effect. The staggered vesting of the separate 10,000-option block restores some alignment over two years. Impact judged immaterial to ownership structure given LIXT’s micro-float.

Panoramica della presentazione del Modulo 4: Il 30/06/2025, il direttore di Lixte Biotechnology Holdings (LIXT), Dr. Yun Yen, ha ricevuto due nuove concessioni di opzioni. La prima riguarda 10.000 azioni con un prezzo di esercizio di 0,905 $, che maturano in otto rate trimestrali uguali a partire dal 30/09/2025. La seconda concessione prevede 11.632 opzioni allo stesso prezzo, con maturazione immediata in sostituzione della compensazione trimestrale in contanti del consiglio. Dopo queste concessioni, il Dr. Yen detiene direttamente un mix di opzioni emesse in precedenza dal 2018 al 2025 con prezzi di esercizio che vanno da 0,905 $ a 66 $, oltre a 5.263 warrant detenuti indirettamente tramite Sino-American Cancer FDD. Non sono state acquistate o vendute azioni ordinarie e tutte le transazioni riguardano esclusivamente strumenti derivati. La presentazione indica un continuo allineamento basato su equity tra il direttore e gli azionisti, senza però rivelare transazioni in contanti o variazioni nel numero totale di azioni.

Resumen de la presentación del Formulario 4: El 30/06/2025, el director de Lixte Biotechnology Holdings (LIXT), Dr. Yun Yen, recibió dos nuevas concesiones de opciones. La primera cubre 10.000 acciones con un precio de ejercicio de $0.905, que se consolidan en ocho cuotas trimestrales iguales a partir del 30/09/2025. La segunda concesión otorga 11.632 opciones al mismo precio, con consolidación inmediata en lugar de la compensación trimestral en efectivo del consejo. Tras las concesiones, el Dr. Yen posee directamente una combinación de opciones emitidas previamente desde 2018 hasta 2025 con precios de ejercicio que van desde $0.905 hasta $66, además de 5.263 warrants mantenidos indirectamente a través de Sino-American Cancer FDD. No se compraron ni vendieron acciones comunes, y todas las transacciones involucran únicamente valores derivados. La presentación indica una alineación continua basada en acciones entre el director y los accionistas, pero no revela transacciones en efectivo ni cambios en el número total de acciones.

Form 4 제출 개요: 2025년 6월 30일, Lixte Biotechnology Holdings(LIXT)의 이사 Dr. Yun Yen이 두 건의 새로운 옵션 부여를 받았습니다. 첫 번째는 행사 가격이 $0.90510,000주로, 2025년 9월 30일부터 8번의 동일한 분기별 할부로 베스팅됩니다. 두 번째 부여는 동일한 가격에 11,632 옵션으로, 분기별 현금 이사회 보상 대신 즉시 베스팅됩니다. 이 부여 이후 Dr. Yen은 2018년부터 2025년까지 발행된 다양한 옵션을 직접 보유하고 있으며, 행사가격은 $0.905에서 $66까지 다양합니다. 또한 Sino-American Cancer FDD를 통해 간접적으로 보유한 5,263 워런트도 포함됩니다. 보통주는 매매되지 않았으며, 모든 거래는 파생 증권에만 해당됩니다. 제출 내용은 이사와 주주 간의 지속적인 주식 기반 정렬을 나타내지만, 현금 거래나 총 주식 수의 변동은 공개하지 않습니다.

Présentation du dépôt du formulaire 4 : Le 30/06/2025, le directeur de Lixte Biotechnology Holdings (LIXT), Dr. Yun Yen, a reçu deux nouvelles attributions d'options. La première concerne 10 000 actions à un prix d'exercice de 0,905 $, acquises en huit versements trimestriels égaux à partir du 30/09/2025. La seconde attribution offre 11 632 options au même prix, avec une acquisition immédiate en remplacement de la rémunération trimestrielle en espèces du conseil d'administration. Suite à ces attributions, le Dr Yen détient désormais directement un mélange d'options émises précédemment entre 2018 et 2025, avec des prix d'exercice allant de 0,905 $ à 66 $, ainsi que 5 263 bons de souscription détenus indirectement via Sino-American Cancer FDD. Aucune action ordinaire n'a été achetée ou vendue, toutes les transactions impliquant uniquement des titres dérivés. Le dépôt indique un alignement continu basé sur les actions entre le directeur et les actionnaires, sans divulguer de transactions en espèces ni de changements dans le nombre total d'actions.

Überblick über die Form 4 Einreichung: Am 30.06.2025 erhielt Dr. Yun Yen, Direktor von Lixte Biotechnology Holdings (LIXT), zwei neue Optionszuweisungen. Die erste umfasst 10.000 Aktien zu einem Ausübungspreis von 0,905 $, die in acht gleichen vierteljährlichen Raten ab dem 30.09.2025 vesten. Die zweite Zuweisung beinhaltet 11.632 Optionen zum gleichen Preis, die sofort vesten und anstelle einer vierteljährlichen Barvergütung des Vorstands gewährt werden. Nach den Zuweisungen hält Dr. Yen nun direkt eine Mischung aus zuvor ausgegebenen Optionen von 2018 bis 2025 mit Ausübungspreisen zwischen 0,905 $ und 66 $, sowie 5.263 Warrants, die indirekt über Sino-American Cancer FDD gehalten werden. Es wurden keine Stammaktien gekauft oder verkauft, und alle Transaktionen betreffen ausschließlich derivative Wertpapiere. Die Einreichung zeigt eine fortgesetzte aktienbasierte Ausrichtung zwischen dem Direktor und den Aktionären, gibt jedoch keine Auskunft über Bargeldtransaktionen oder Änderungen der Gesamtzahl der Aktien.

SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Estimated average burden
hours per response: 0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Yen Yun

(Last) (First) (Middle)
680 E. COLORADO BLVD., SUITE 180

(Street)
PASADENA CA 91101

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
LIXTE BIOTECHNOLOGY HOLDINGS, INC. [ LIXT ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
X Director 10% Owner
Officer (give title below) Other (specify below)
3. Date of Earliest Transaction (Month/Day/Year)
06/30/2025
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Options to Purchase Common Stock $0.905 06/30/2025 A 10,000 09/30/2025 06/30/2030 Common 10,000 $0(1) 10,000 D
Options to Purchase Common Stock $0.905 06/30/2025 A 11,632 06/30/2025 06/30/2030 Common 11,652 $0(2) 11,632 D
Options to Purchase Common Stock $1.21 03/31/2025 03/31/2030 Common 8,777 8,777 D
Options to Purchase Common Stock $2.33 01/20/2025 01/20/2030 Common 4,545 4,545 D
Options to Purchase Common Stock $1.3 09/30/2024 09/30/2029 Common 5,786 5,786 D
Options to Purchase Common Stock $2.37 06/30/2024 06/30/2029 Common 10,000 10,000 D
Options to Purchase Common Stock $2.37 06/30/2024 06/30/2029 Common 4,527 4,527 D
Options to Purchase Common Stock $7.45 06/30/2022 06/30/2027 Common 10,000 10,000 D
Options to Purchase Common Stock $30.3 06/30/2021 06/30/2026 Common 10,000 10,000 D
Options to Purchase Common Stock $32.1 01/06/2021 01/06/2026 Common 5,000 5,000 D
Warrants to Purchase Common Stock $57 11/30/2020 11/30/2025 Common 5,263 5,263 I By Sino-American Cancer FDD
Options to Purchase Common Stock $16.8 08/04/2018 08/04/2023 Common 3,333 3,333 D
Options to Purchase Common Stock $66 05/22/2019 05/22/2024 Common 833 833 D
Explanation of Responses:
1. Effective June 30, 2025, the reporting person was granted stock options to purchase an aggregate of 10,000 shares vesting in eight equal installments on the last day of each subsequent quarter until fully vested with vesting to start on September 30, 2025.
2. Effective June 30, 2025 the reporting person was granted stock options in aggregate of 11,632 vesting immediately. The grant was in lieu of the quarterly cash compensation due to the reporting person under the Board Compensation Plan.
/s/ Yun Yen 07/09/2025
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What securities did Dr. Yun Yen acquire according to the 06/30/2025 Form 4 for LIXT?

Dr. Yen received 21,632 stock options at an exercise price of $0.905 per share.

Why were 11,632 LIXT options granted immediately to Dr. Yen?

They were issued in lieu of quarterly cash compensation owed under the Board Compensation Plan.

When do the 10,000 newly granted LIXT options begin vesting?

Vesting starts on 09/30/2025 and occurs in eight equal quarterly installments.

Does the Form 4 show any purchase or sale of LIXT common shares?

No. The filing reports only derivative (option and warrant) transactions; no common shares changed hands.

What is the lowest exercise price among Dr. Yen’s reported options?

The lowest strike price disclosed is $0.905 per share for the 2025 option grants.
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Biotechnology
Pharmaceutical Preparations
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United States
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