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Lantern Pharma (Nasdaq: LTRN) creates Open-Medicine AI to license its multi-agent platform

(Moderate)
(Neutral)
Form Type
8-K

Rhea-AI Filing Summary

Lantern Pharma Inc. announced the formal creation of Open-Medicine AI (OMAI) as a separate company to commercialize and expand its multi-agent AI co-scientist platform, previously launched as withZeta.ai. OMAI and Lantern have executed commercial licensing agreements, approved by Lantern’s Board and consistent with the framework outlined in Lantern’s May 2026 registered direct financing. These agreements grant OMAI access to Lantern’s withZeta.ai-related models, data, algorithms, and other assets and personnel, positioning OMAI for independent growth while preserving strategic alignment with Lantern’s clinical programs and shareholders.

OMAI will advance a multi-agentic architecture first proven in oncology and rare cancer research and extend it into broader disease areas. Lantern has established Centers of Excellence in Dallas, Texas and Bengaluru, India, with the Bengaluru AI Center of Excellence created in the first quarter of 2026 to support development, refinement, and scaling of the Open-Medicine platform. Lantern cites projections that the global AI drug discovery and development market could exceed $10 billion by 2030, with oncology as the largest segment and compound annual growth rates above 30 percent. The platform includes coordinated specialist agents, multiple research modes, proprietary rare-cancer knowledge bases, and tools such as ZetaOmics™ for multi-omic analysis and generative chemistry capabilities, and is intended to pursue a dedicated funding and valuation path distinct from Lantern’s clinical activities.

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Filing Explained

This Form 8-K reports the creation of Open-Medicine AI and executed commercial licenses, but the announcement is furnished under Item 7.01 and is not treated as filed for Section 18 purposes.

Item 7.01 Regulation FD Disclosure Disclosure
Material non-public information disclosed under Regulation Fair Disclosure, often investor presentations or guidance.
Item 9.01 Financial Statements and Exhibits Exhibits
Financial statements, pro forma financial information, and exhibit attachments filed with this report.
Projected AI drug discovery market size $10 billion Projected global AI drug discovery and development market size by 2030
Projected CAGR for AI drug discovery tools above 30 percent Compound annual growth rates for AI-enabled drug discovery and development tools
Formation date of Open-Medicine AI August 3, 2026 Date Lantern Pharma announced the formal creation of Open-Medicine AI
Bengaluru AI Center establishment first quarter of 2026 Quarter in which Lantern established an AI Center of Excellence in Bengaluru, India
multi-agentic co-scientist platform technical
"the multi-agentic co-scientist platform previously launched as withZeta.ai"
registered direct financing financial
"framework outlined in Lantern’s most recent registered direct financing"
A registered direct financing is when a company sells newly registered securities directly to a limited number of investors under an existing registration, skipping the broad public marketing of a typical offering; think of it as putting approved items on a store shelf and arranging a private sale to select buyers. Investors care because it can quickly raise cash while creating new shares or debt that may dilute existing ownership, affect the share price and change the company’s financial runway.
Center of Excellence technical
"established and staffed an AI Center of Excellence in Bengaluru, India"
A "Center of Excellence" is a dedicated team or group within a company that specializes in a particular area, like technology or customer service. It helps the company improve practices, share best ideas, and stay ahead by focusing on expertise, much like a sports team with experts who lead training and strategies.
multi-omic analysis medical
"including ZetaOmics™ for multi-omic analysis and continued development"
forward-looking statements regulatory
"This press release contains forward-looking statements within the meaning"
Forward-looking statements are predictions or plans that companies share about what they expect to happen in the future, like estimating sales or profits. They matter because they help investors understand a company's outlook, but since they are based on guesses and assumptions, they can sometimes be wrong.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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FAQ

What did Lantern Pharma (LTRN) announce about Open-Medicine AI?

Lantern Pharma announced the formal creation of Open-Medicine AI (OMAI) as a separate company to commercialize its multi-agent AI co-scientist platform. OMAI is built on the withZeta.ai system and is positioned for independent growth while remaining strategically aligned with Lantern’s clinical programs.

What agreements exist between Lantern Pharma (LTRN) and Open-Medicine AI?

Lantern Pharma has executed commercial licensing agreements with Open-Medicine AI, granting access to Lantern’s withZeta.ai-related models, data, algorithms, and other assets and personnel. These Board-approved agreements follow the framework from Lantern’s May 2026 registered direct financing.

What market opportunity does Lantern Pharma (LTRN) highlight for Open-Medicine AI?

Lantern cites projections that the global AI drug discovery and development market could exceed $10 billion by 2030, with compound annual growth rates above 30 percent. Oncology is described as the largest therapeutic segment, aligning with OMAI’s initial focus in cancer and rare diseases.

What role do Dallas and Bengaluru centers play in Lantern Pharma’s (LTRN) AI efforts?

Lantern has Centers of Excellence in Dallas, Texas and Bengaluru, India. The Bengaluru AI Center of Excellence, established in the first quarter of 2026, serves as an operational hub to accelerate development, refinement, and scaling of the Open-Medicine platform alongside the existing Dallas team.

How does Lantern Pharma’s May 2026 registered direct financing relate to Open-Medicine AI (LTRN)?

Lantern states that creation of Open-Medicine AI, related licensing agreements, and Board approvals are consistent with agreements entered into in connection with its May 2026 registered direct financing, reflecting a previously outlined framework for commercializing the AI co-scientist platform.
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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

FORM 8-K

 

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

 

Date of Report (Date of earliest event reported): August 3, 2026

 

Lantern Pharma Inc.

(Exact name of registrant as specified in its charter)

 

Delaware   001-39318   46-3973463

(State or Other Jurisdiction

of Incorporation)

 

(Commission

File Number)

 

(IRS Employer

Identification No.)

 

1920 McKinney Avenue, 7th Floor

Dallas, Texas

  75201
(Address of Principal Executive Offices)   (Zip Code)

 

(972) 277-1136

(Registrant’s telephone number, including area code)

 

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

 

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
   
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
   
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
   
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

 

Securities registered pursuant to Section 12(b) of the Act: Common Stock

 

Title of each class   Trading Symbol   Name of each exchange on which registered
Common Stock, $0.0001 par value   LTRN   The Nasdaq Stock Market

 

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

 

Emerging growth company

 

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

 

 

 

 

 

 

Item 7.01 Regulation FD Disclosure.

 

On August 3, 2026, Lantern Pharma Inc. (“Lantern”) issued a press release announcing the establishment of Open-Medicine AI as a separate company to commercialize and expand its multi-agent AI co-scientist platform for drug development. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference.

 

The information in this Item 7.01, including Exhibit 99.1 hereto, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filings under the Securities Act of 1933, as amended, or the Exchange Act, regardless of any general incorporation language in such filings, unless expressly incorporated by specific reference in such filing.

 

Item 9.01 Financial Statements and Exhibits.

 

(d) Exhibits.

 

Exhibit No.   Exhibit Description
     
99.1   Press Release dated August 3, 2026 announcing the establishment of Open-Medicine AI.
104   Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101).

 

2

 

 

SIGNATURES

 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

  Lantern Pharma Inc.,
  A Delaware Corporation
     
Dated: August 3, 2026 By: /s/ David R. Margrave
    David R. Margrave, Chief Financial Officer

 

3

 

 

Exhibit 99.1

 

 

Lantern Pharma (Nasdaq: LTRN) Establishes Open-Medicine AI as a Separate Company to Commercialize and Expand Its Multi-Agent AI Co-Scientist Platform for the Transformation of Medicine

 

  The Open-Medicine AI multi-agentic co-scientist platform represents the strategic evolution of withZeta.ai and is expanding into additional disease areas and modalities.
  The creation of the new entity, signed commercial licenses, and Board approvals are consistent with the agreements entered into in connection with Lantern’s May financing.
  Lantern Pharma has executed commercial licensing agreements with Open-Medicine AI granting access to Lantern’s withZeta.ai-related models, data, algorithms, and other assets and personnel.
  The global AI drug discovery and development market is projected to exceed $10 billion by 2030, and Open-Medicine AI enters this market with a differentiated multi-agentic, highly curated platform built for real-world drug development rather than a general-purpose AI.

 

(BUSINESS WIRE) DALLAS – August 3, 2026 — Lantern Pharma Inc. (Nasdaq: LTRN), a clinical-stage AI-driven precision oncology company, today announced the formal creation of Open-Medicine AI (OMAI) and the execution of commercial licensing agreements between OMAI and Lantern Pharma. The agreements, which have received Lantern Pharma Board approval, are consistent with the framework outlined in Lantern’s most recent registered direct financing and establish the commercial operating structure for the multi-agentic AI co-scientist platform previously launched as withZeta.ai.

 

OMAI will continue to advance the multi-agentic architecture, first proven in oncology and rare cancer research, while expanding its application across broader disease areas. The formation of the entity and the licensing arrangements position OMAI for independent growth, while expanding value creation opportunities and preserving strategic alignment with Lantern Pharma’s clinical programs and shareholders.

 

“The creation of Open-Medicine AI and the execution of these licensing agreements mark a significant milestone,” said Panna Sharma, President and CEO of Lantern Pharma and Founder of Open-Medicine AI. “withZeta.ai demonstrated that a true multi-agentic co-scientist — specialized agents working in coordinated intelligence rather than a single model answering isolated questions — can dramatically compress research timelines and reduce the cost of generating hardened, actionable scientific insights. Open-Medicine AI takes that proven foundation and gives it the corporate structure, commercial licenses, and operational focus needed to scale across oncology and into additional complex disease areas.”

 

Lantern Launches Open-Medicine AI : From Idea to Medicine at the Speed of Insight
 
Lantern Pharma (Nasdaq: LTRN)                        Aug 3, 2026
 

 

 

AI Centers of Excellence in Dallas, Texas and Bengaluru, India

 

In the first quarter of 2026, Lantern established and staffed an AI Center of Excellence in Bengaluru, India. This center will serve as a core operational hub accelerating the development, refinement, and scaling of the Open-Medicine platform. The Bengaluru team will bring additional specialized talent to the existing team in Dallas (where Lantern is also headquartered). Both sites will focus on functional enhancements in multi-agent systems, computational biology modeling, knowledge engineering, and large-scale scientific curation — furthering Open-Medicine’s ability to deliver production-grade capabilities to researchers and institutions worldwide.

 

Market Need and Competitive Landscape

 

The global market for AI-enabled drug discovery and development tools is projected to exceed $10 billion by 2030, with oncology representing the largest therapeutic segment and compound annual growth rates above 30 percent. The underlying need is structural: traditional drug development remains slow, expensive, and poorly suited to the hundreds of rare and complex diseases that lack commercial scale under conventional models. Knowledge remains fragmented across literature, clinical trial databases, institutional archives, and individual expertise, while experimental iteration continues to consume months or years and hundreds of thousands to millions of dollars per cycle.

 

At the same time, major general-purpose AI companies — including Anthropic and OpenAI — have publicly signaled or begun developing platforms and tools aimed at scientific discovery and drug development. Their entrance validates the long-term importance of AI co-scientists while also highlighting the differentiation required for durable impact. While general models excel at broad reasoning and language, domain-specific multi-agentic systems grounded in curated ontologies, domain-specific computational tools, and disease-area expertise are required to deliver the precision, auditability, and scientific rigor demanded by drug development.

 

OMAI is uniquely positioned for differentiated value creation at this intersection. Built from the ground up for oncology and rare disease research and drug-development, the platform combines specialized agent roles, recursive investigation modes, living knowledge graphs, and production tools (including blood-brain barrier prediction, multi-omic analytics via ZetaOmics™, and generative chemistry capabilities). Its architecture is designed not merely to retrieve information but to generate, stress-test, and harden insights in a manner that mirrors how expert scientific teams actually work – iteratively, collaboratively and focused on actionable results.

 

Lantern Launches Open-Medicine AI : From Idea to Medicine at the Speed of Insight
 
Lantern Pharma (Nasdaq: LTRN)                        Aug 3, 2026
 

 

The May 2026 financing of Lantern Pharma’s registered direct was led by Empery Asset Management, LP and also included an existing institutional healthcare investor and Lantern Board members. Mr. Ryan Lane, CIO and founder of Empery Asset Management stated,

 

“At Empery, we continue to be impressed by the relevance and usefulness of the insights and results generated by withZeta.AI’s co-scientist platform. Among the various enterprise level agentic AI toolings we use, withZeta.AI continues to be our preferred platform for AI-assisted biopharma due diligence and research.”

 

Platform Foundation and Expansion Path

 

OMAI inherits the full multi-agentic system originally commercialized as withZeta.ai, including:

 

  Coordinated specialist agents spanning medicinal chemistry, computational biology, clinical trial strategy, biomarkers & translational science, clinical oncology, and general research.
  Three research modes (Explorer, Investigator, Reporter) that support rapid exploration through deep multi-source investigation to structured reporting.
  Proprietary rare-cancer knowledge bases and ontologies covering hundreds of disease entities, biomarkers, clinical trials, and literature.
  Expanding computational layers, including ZetaOmics™ for multi-omic analysis and continued development of parallel swarm intelligence capabilities.

 

While rare cancers remain a core component, OMAI’s roadmap includes systematic expansion into additional high-need disease areas – especially in collaboration with leading academic and commercial leaders – that experience the same challenges of fragmented knowledge, high failure costs, limited traditional investment and urgency of patient and disease management needs.

 

“Open-Medicine AI is built to change how medicines are discovered and developed globally, and as a separate company, to pursue dedicated funding and a valuation path distinct from Lantern’s clinical activity and operations.” – Panna Sharma, CEO & President of Lantern Pharma

 

About Lantern Pharma Inc.

 

Lantern Pharma Inc. (Nasdaq: LTRN) is a clinical-stage precision oncology company leveraging artificial intelligence and machine learning to transform cancer therapy development. The Company’s pipeline includes LP-184, LP-284, and LP-300. Lantern established an AI Center of Excellence in Bengaluru, India, in the first quarter of 2026 and has commercialized its multi-agentic AI capabilities through the platform now operating as Open-Medicine AI (OMAI).

 

Lantern Launches Open-Medicine AI : From Idea to Medicine at the Speed of Insight
 
Lantern Pharma (Nasdaq: LTRN)                        Aug 3, 2026
 

 

 

About Open-Medicine AI (OMAI)

 

Open-Medicine AI builds multi-agentic systems that do the work of a research team — generating novel insights, interrogating literature and data, and pressure-testing conclusions until they hold, all with transparent, auditable reasoning. The platform was built inside active drug development at Lantern Pharma, where its output and insights had to survive contact with real programs, real regulators, and real patients. Most discovery AI has never been held to that standard. Open-Medicine AI is planned to operate beyond rare cancers, across oncology and into other diseases where the science is hard and the answers are overdue.

 

Forward-Looking Statements

 

This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. These forward-looking statements include, among other things, statements relating to: future events or our future financial performance; the establishment of our Open-Medicine AI platform (formerly referred to as withZeta.ai) as a separate business entity and the anticipated benefits of such separation; the formation, re-branding and planned commercialization of our Open-Medicine AI platform; the planned development, design, capabilities, and commercial potential of the Open-Medicine AI platform, including the role of the Bengaluru AI Center of Excellence; our broader product, clinical, and platform roadmap, including future directions for Open-Medicine AI and the planned implementation of new features; the potential advantages of our Open-Medicine AI platform in identifying drug candidates, accelerating drug development, and generating revenue through software licensing and subscription models; the planned commercialization of Open-Medicine AI, and the expected market opportunity for AI co-scientist platforms; our intention to leverage artificial intelligence, machine learning and genomic data to streamline and transform the pace, risk and cost of oncology drug discovery and development; and estimates regarding potential markets and potential market sizes.

 

Any statements that are not statements of historical fact (including, without limitation, statements that use words such as “anticipate,” “believe,” “contemplate,” “could,” “estimate,” “expect,” “intend,” “seek,” “may,” “might,” “plan,” “potential,” “predict,” “project,” “target,” “model,” “objective,” “aim,” “upcoming,” “should,” “will,” “would,” or the negative of these words or other similar expressions) should be considered forward-looking statements. There are a number of important factors that could cause our actual results to differ materially from those indicated by the forward-looking statements, such as (i) the risk that we may not be able to secure sufficient future funding when needed and as required to advance and support our existing and planned development programs and operations, (ii) the risk that our Open-Medicine AI commercialization efforts may not generate the anticipated revenue or achieve the expected market adoption, (iii) the risk that implementation of our product development plans and new features for Open-Medicine AI may not be successful or may take longer than anticipated for development, completion, and release, (iv) the risk that no drug product based on our proprietary AI platforms has received FDA marketing approval or otherwise been incorporated into a commercial product, and (v) technical, scientific, regulatory, financial, competitive, and operational risks and those other factors set forth in the Risk Factors section in our Annual Report on Form 10-K for the year ended December 31, 2025, filed with the Securities and Exchange Commission on March 30, 2026.

 

You may access our Annual Report on Form 10-K for the year ended December 31, 2025 under the investor SEC filings tab of our website at www.lanternpharma.com or on the SEC’s website at www.sec.gov. Given these risks and uncertainties, we can give no assurances that our forward-looking statements will prove to be accurate, or that any other results or events projected or contemplated by our forward-looking statements will in fact occur, and we caution investors not to place undue reliance on these statements. All forward-looking statements in this press release represent our judgment as of the date hereof, and, except as otherwise required by law, we disclaim any obligation to update any forward-looking statements to conform the statement to actual results or changes in our expectations.

 

Investor Relations Contact

 

Lantern Pharma Inc.

E-mail: ir@lanternpharma.com

Website: ir.lanternpharma.com

Phone: +1-972-277-1136

 

Lantern Launches Open-Medicine AI : From Idea to Medicine at the Speed of Insight
 
Lantern Pharma (Nasdaq: LTRN)                        Aug 3, 2026

 

Filing Exhibits & Attachments

5 documents