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Lexicon Pharmaceuticals (LXRX) CMO reports RSU vesting and tax share withholding

Filing Impact
(Moderate)
Filing Sentiment
(Neutral)
Form Type
4

Rhea-AI Filing Summary

LEXICON PHARMACEUTICALS, INC. Senior Vice President and Chief Medical Officer Craig B. Granowitz reported multiple equity award transactions involving restricted stock units and common stock on February 28, 2026.

He exercised or converted restricted stock units into common shares in three separate transactions of 35,790, 74,226, and 202,260 restricted stock units, each at a stated price of $0.00 per unit. Each restricted stock unit represents a contingent right to receive one share of common stock, and these units vest in three equal annual installments on February 28 of each of the three years following the year of grant.

Corresponding non-derivative entries show acquisitions of common stock in matching amounts of 35,790, 74,226, and 202,260 shares, reflecting the settlement of those restricted stock units. A separate transaction disposed of 109,098 shares of common stock at $1.47 per share through withholding of a portion of the issued shares by the company to satisfy the reporting person’s tax withholding obligations. After these transactions, the reporting person directly owned 323,430 shares of common stock.

Positive

  • None.

Negative

  • None.
Insider Granowitz Craig B
Role SVP, Chief Medical Officer
Type Security Shares Price Value
Exercise Restricted Stock Units 35,790 $0.00 --
Exercise Restricted Stock Units 74,226 $0.00 --
Exercise Restricted Stock Units 202,260 $0.00 --
Exercise Common Stock 35,790 $0.00 --
Exercise Common Stock 74,226 $0.00 --
Exercise Common Stock 202,260 $0.00 --
Tax Withholding Common Stock 109,098 $1.47 $160K
Holdings After Transaction: Restricted Stock Units — 0 shares (Direct); Common Stock — 156,042 shares (Direct)
Footnotes (1)
  1. Each restricted stock unit represents a contingent right to receive one share of common stock. Withholding of a portion of issued shares by the Company in satisfaction of shareholder's tax withholding obligations with respect thereto. Restricted stock units vest with respect to 1/3 of the shares subject to the restricted stock units on February 28 of each of the three years following the year of grant.
Form 4 Insider Transactions: What Each Field Means →
SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Estimated average burden
hours per response: 0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Granowitz Craig B
(Last) (First) (Middle)
2445 TECHNOLOGY FOREST BLVD.
11TH FLOOR
(Street)
THE WOODLANDS TX 77381
(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
LEXICON PHARMACEUTICALS, INC. [ LXRX ] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director 10% Owner
X Officer (give title below) Other (specify below)
SVP, Chief Medical Officer
3. Date of Earliest Transaction (Month/Day/Year)
02/28/2026
4. If Amendment, Date of Original Filed (Month/Day/Year)
 6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 02/28/2026 M 35,790 A (1) 156,042 D
Common Stock 02/28/2026 M 74,226 A (1) 230,268 D
Common Stock 02/28/2026 M 202,260 A (1) 432,528 D
Common Stock 02/28/2026 F(2) 109,098 D $1.47 323,430 D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Restricted Stock Units (1) 02/28/2026 M 35,790 (3) (3) Common Stock 35,790 (1) 0 D
Restricted Stock Units (1) 02/28/2026 M 74,226 (3) (3) Common Stock 74,226 (1) 74,227 D
Restricted Stock Units (1) 02/28/2026 M 202,260 (3) (3) Common Stock 202,260 (1) 404,520 D
Explanation of Responses:
1. Each restricted stock unit represents a contingent right to receive one share of common stock.
2. Withholding of a portion of issued shares by the Company in satisfaction of shareholder's tax withholding obligations with respect thereto.
3. Restricted stock units vest with respect to 1/3 of the shares subject to the restricted stock units on February 28 of each of the three years following the year of grant.
/s/ Craig B. Granowitz, M.D., Ph.D. 03/03/2026
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

Source: View Original Filing on SEC EDGAR

FAQ

What insider transactions did LXRX executive Craig Granowitz report on this Form 4?

Craig Granowitz reported exercises of restricted stock units into common stock and a related tax-withholding disposition. He converted units into 35,790, 74,226, and 202,260 common shares, and 109,098 shares were withheld by the company to cover associated tax obligations.

How many Lexicon Pharmaceuticals (LXRX) shares did the CMO acquire through equity awards?

The CMO acquired common stock through settlement of three restricted stock unit grants. These transactions corresponded to 35,790, 74,226, and 202,260 restricted stock units, each representing a contingent right to one share of common stock, vesting in three equal annual installments after the grant year.

Why were 109,098 LXRX shares disposed of in Craig Granowitz’s Form 4 filing?

The 109,098 shares of Lexicon common stock were withheld by the company to satisfy the reporting person’s tax withholding obligations. This disposition used transaction code F, indicating payment of tax liability by delivering securities rather than an open-market sale.

What is the vesting schedule for the Lexicon restricted stock units reported by the CMO?

The restricted stock units vest over three years. One-third of the shares subject to each restricted stock unit grant vests on February 28 of each of the three years following the year of grant, creating a staggered, time-based vesting schedule tied to continued service.

How many Lexicon Pharmaceuticals (LXRX) shares does the CMO own after these transactions?

After completing the reported exercises, conversions, and tax-withholding disposition, the reporting person directly owned 323,430 shares of Lexicon common stock. This figure reflects the net position following all derivative and non-derivative transactions disclosed for February 28, 2026.