[Form 4] LEXICON PHARMACEUTICALS, INC. Insider Trading Activity

LEXICON PHARMACEUTICALS director Judith L. Swain received new equity awards as part of her compensation.

Rhea-AI Filing Summary

LEXICON PHARMACEUTICALS director Judith L. Swain received new equity awards as part of her compensation. On May 1, 2026, she was granted stock options for 43,478 shares of common stock at an exercise price of $1.61 per share, vesting in three equal annual installments on each of the first three anniversaries of the grant date and expiring on May 1, 2036. She was also granted 35,714 restricted stock units, which vest in full on the first anniversary of the grant date. Each restricted stock unit represents a contingent right to receive one share of common stock.

Insider Trade Summary

Grant/Award: 79,192 shares

Grant/Award 2 txns

Insider Swain Judith L

Role Director

Type	Security	Shares	Price	Value
Grant/Award	Restricted Stock Units	35,714	$0.00	$0.00
Grant/Award	Stock Option (Right to Buy)	43,478	$0.00	$0.00

Holdings After Transaction: Restricted Stock Units — 35,714 contracts (Direct); Stock Option (Right to Buy) — 43,478 contracts (Direct)

Footnotes (3)

1. F1. Restricted stock unit vests with respect to 100% of the shares subject to the restricted stock unit on the first anniversary of the grant date.
2. F2. Each restricted stock unit represents a contingent right to receive one share of common stock.
3. F3. Option vests with respect to one third of the shares subject to the option on each of the first three anniversaries of the grant date.

Key Figures

Stock options granted: 43,478 options Option exercise price: $1.61 per share Option expiration: May 1, 2036 +1 more

4 metrics

Stock options granted 43,478 options Granted May 1, 2026 to director Judith L. Swain

Option exercise price $1.61 per share Exercise price for stock options granted May 1, 2026

Option expiration May 1, 2036 Expiration date of granted stock options

RSUs granted 35,714 RSUs Restricted stock units granted May 1, 2026

Key Terms

Stock Option (Right to Buy), Restricted Stock Units, exercise price, vests, +1 more

5 terms

Stock Option (Right to Buy) financial

"security_title: Stock Option (Right to Buy)"

Restricted Stock Units financial

"security_title: Restricted Stock Units"

Restricted stock units are a type of company reward where employees are promised shares of stock, but they only fully own these shares after meeting certain conditions, like staying with the company for a set time. They matter because they can become valuable assets and are often used to motivate employees to help the company succeed.

exercise price financial

"conversion_or_exercise_price: 1.6100"

The exercise price is the fixed amount at which you can buy or sell an asset, like a stock, when using an options contract. It matters because it helps determine whether exercising the option will be profitable or not, depending on the current market price. Think of it as the set price you agree on today to buy or sell later.

vests financial

"Option vests with respect to one third of the shares"

contingent right financial

"represents a contingent right to receive one share"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What insider transactions did LXRX director Judith Swain report?

Judith Swain reported equity compensation grants, not open-market trades. She received stock options on 43,478 shares at $1.61 per share and 35,714 restricted stock units, both tied to service-based vesting schedules rather than immediate share deliveries or sales.

How many stock options did Judith Swain receive from Lexicon (LXRX)?

She received stock options covering 43,478 shares of Lexicon common stock. These options vest in three equal installments on each of the first three anniversaries of the May 1, 2026 grant date, and they carry a $1.61 per share exercise price.

What are the terms of the restricted stock units granted by Lexicon (LXRX)?

Judith Swain was granted 35,714 restricted stock units. The award vests 100% on the first anniversary of the May 1, 2026 grant date. Each restricted stock unit converts into one share of Lexicon common stock when the vesting conditions are satisfied.

When do Judith Swain’s Lexicon stock options expire?

The stock options granted to Judith Swain on May 1, 2026 expire on May 1, 2036. She can exercise them after they vest, in three equal annual tranches, at an exercise price of $1.61 per share, subject to Lexicon’s equity plan rules.

Are Judith Swain’s Lexicon (LXRX) equity awards open-market purchases?

No. The Form 4 shows grants classified as acquisitions under code A, representing compensation awards. They are stock options and restricted stock units awarded by Lexicon, not shares bought or sold in the open market by Judith Swain.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 05/04/2026 - 04:27 PM EDT Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Swain Judith L

(Last) (First) (Middle)

2445 TECHNOLOGY FOREST BLVD.

11TH FLOOR

(Street)

THE WOODLANDS TEXAS 77381

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
LEXICON PHARMACEUTICALS, INC. [ LXRX ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
05/01/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Restricted Stock Units	$0	05/01/2026		A		35,714		(1)	(2)	Common Stock	35,714	$0	35,714	D
Stock Option (Right to Buy)	$1.61	05/01/2026		A		43,478		(3)	05/01/2036	Common Stock	43,478	$0	43,478	D

Explanation of Responses:

1. Restricted stock unit vests with respect to 100% of the shares subject to the restricted stock unit on the first anniversary of the grant date.

2. Each restricted stock unit represents a contingent right to receive one share of common stock.

3. Option vests with respect to one third of the shares subject to the option on each of the first three anniversaries of the grant date.

	/s/ Judith L. Swain	05/04/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)