Lexicon director exercises 89,312 RSUs into shares

LEXICON PHARMACEUTICALS, INC. director Philippe Amouyal exercised restricted stock units into common shares.

Rhea-AI Filing Summary

LEXICON PHARMACEUTICALS, INC. director Philippe Amouyal exercised restricted stock units into common shares. On June 3, 2026, he converted 89,312 restricted stock units into the same number of common shares at a stated price of $0.00 per share, reflecting a compensation-related vesting rather than a market purchase or sale. After the transaction, he held 374,486 common shares directly. The derivative position in these restricted stock units was fully settled, leaving no remaining units from this grant.

Insider Trade Summary

89,312 shares exercised/converted

Exercise 2 txns

Insider Amouyal Philippe

Role Director

Type	Security	Shares	Price	Value
Exercise	Restricted Stock Units	89,312	$0.00	$0.00
Exercise	Common Stock	89,312	$0.00	$0.00

Holdings After Transaction: Restricted Stock Units — 0 contracts (Direct); Common Stock — 374,486 shares (Direct)

Footnotes (2)

1. F1. Restricted stock unit vests with respect to 100% of the shares subject to the restricted stock unit on the first anniversary of the grant date.
2. F2. Each restricted stock unit represents a contingent right to receive one share of common stock.

Key Figures

RSUs exercised: 89,312 units Common shares received: 89,312 shares Shares held after transaction: 374,486 shares +2 more

5 metrics

RSUs exercised 89,312 units Restricted stock units converted to common stock on June 3, 2026

Common shares received 89,312 shares Shares issued upon RSU exercise

Shares held after transaction 374,486 shares Director’s direct common stock holdings following RSU conversion

Exercise price $0.00 per share Stated transaction price for RSU conversion

RSUs remaining from this grant 0 units Restricted stock units of this grant after exercise

Key Terms

Restricted Stock Units, contingent right, derivative security

3 terms

Restricted Stock Units financial

"Restricted stock unit vests with respect to 100% of the shares subject to the restricted stock unit on the first anniversary of the grant date."

Restricted stock units are a type of company reward where employees are promised shares of stock, but they only fully own these shares after meeting certain conditions, like staying with the company for a set time. They matter because they can become valuable assets and are often used to motivate employees to help the company succeed.

contingent right financial

"Each restricted stock unit represents a contingent right to receive one share of common stock."

derivative security financial

"Exercise or conversion of derivative security"

A derivative security is a financial contract whose value comes from the price or performance of something else, such as a stock, bond, commodity, or market index. For investors it acts like an insurance policy or a wager: it can be used to protect against losses, lock in prices, or amplify gains and losses, so it can change a portfolio’s risk and potential return without owning the underlying asset directly.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What insider transaction did LXRX director Philippe Amouyal report?

Philippe Amouyal reported exercising 89,312 restricted stock units into common stock. This conversion reflects previously granted equity vesting, not an open-market buy or sell, and increased his directly held common shares in Lexicon Pharmaceuticals, Inc.

How many LXRX shares does Philippe Amouyal hold after this Form 4?

After the transaction, Philippe Amouyal directly holds 374,486 shares of Lexicon Pharmaceuticals common stock. This includes the 89,312 shares received from exercising restricted stock units disclosed in the Form 4 filing.

Did the LXRX director buy or sell shares on the open market?

The director neither bought nor sold shares on the open market. He exercised 89,312 restricted stock units at a stated price of $0.00 per share, converting them into common stock as part of equity compensation vesting.

What happened to Philippe Amouyal’s restricted stock units in LXRX?

The reported restricted stock units were fully converted into common stock. The Form 4 shows 89,312 restricted stock units exercised, with zero such units remaining from this grant following the transaction on June 3, 2026.

How are LXRX restricted stock units described in this filing?

Each restricted stock unit represents a contingent right to receive one share of Lexicon common stock. The filing notes these units vest 100% on the first anniversary of the grant date before being converted into shares.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 06/04/2026 - 04:10 PM EDT Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Amouyal Philippe

(Last) (First) (Middle)

2445 TECHNOLOGY FOREST BLVD.

11TH FLOOR

(Street)

THE WOODLANDS TEXAS 77381

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
LEXICON PHARMACEUTICALS, INC. [ LXRX ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
06/03/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	06/03/2026		M		89,312	A	$0	374,486	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Restricted Stock Units	$0	06/03/2026		M			89,312	(1)	(2)	Common Stock	89,312	$0	0	D

Explanation of Responses:

1. Restricted stock unit vests with respect to 100% of the shares subject to the restricted stock unit on the first anniversary of the grant date.

2. Each restricted stock unit represents a contingent right to receive one share of common stock.

	/s/ Philippe J. Amouyal	06/04/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)