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Insider group boosts Lexicon (LXRX) stake and funds offering with preferred deal

Filing Impact
(Moderate)
Filing Sentiment
(Neutral)
Form Type
SCHEDULE 13D/A

Rhea-AI Filing Summary

Lexicon Pharmaceuticals’ major shareholders have updated their ownership and financing arrangements following a new capital raise. An investor group led by Artal and Invus now collectively reports beneficial ownership of 205,952,227 Lexicon common shares, representing approximately 48.2% of the 427,084,567 shares outstanding as of the recent financing.

Artal Participations agreed to buy 22,400,000 common shares for $29,120,000 and 367,145.12 shares of Series B convertible preferred stock for $23,864,432.80 in private placements. Invus Public Equities purchased 3,846,154 common shares for $5,000,000.20, and Avicenna Life Sci Master Fund bought 1,538,462 common shares for $2,000,000.60 as part of a 32,000,000‑share underwritten public offering with a 4,800,000‑share option. The new preferred stock will automatically convert into common shares at a 50‑to‑1 ratio once shareholders approve an increase in authorized common shares and related charter steps are completed, subject to antitrust clearance where applicable.

Positive

  • None.

Negative

  • None.

Insights

Large insiders backstop Lexicon’s financing, raising ownership to about 48%.

Lexicon Pharmaceuticals has secured substantial insider participation alongside a 32,000,000‑share public offering with a 4,800,000‑share underwriter option. Artal bought common stock and 367,145.12 preferred shares at $65, while Invus and Avicenna added meaningful common positions using available funds.

The preferred stock automatically converts into 50 common shares per preferred share once shareholders approve higher authorized common shares, the new charter is adopted and filed, and any required Hart‑Scott‑Rodino clearances for conversion are satisfied. Until then, the preferred is non‑voting on common stock matters.

The reporting group’s 205,952,227 shares represent about 48.2% of Lexicon’s 427,084,567 outstanding shares as of the offering closing. A 60‑day lock‑up from January 29, 2026 limits sales or hedging by the investor group, so any future trading activity would likely appear after that period in subsequent disclosures.






If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box.

The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).






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SCHEDULE 13D


Invus, L.P.
Signature:/s/ Raymond Debbane
Name/Title:Raymond Debbane, President of Invus Advisors L.L.C., its general partner
Date:02/02/2026
Invus Advisors, L.L.C.
Signature:/s/ Raymond Debbane
Name/Title:Raymond Debbane, President
Date:02/02/2026
Invus Public Equities, L.P.
Signature:/s/ Raymond Debbane
Name/Title:Raymond Debbane, President of Invus Public Equities Advisors, LLC, its general partner
Date:02/02/2026
Invus Public Equities Advisors, LLC
Signature:/s/ Raymond Debbane
Name/Title:Raymond Debbane, President
Date:02/02/2026
Invus Global Management, LLC
Signature:/s/ Raymond Debbane
Name/Title:Raymond Debbane, President
Date:02/02/2026
Siren, L.L.C.
Signature:/s/ Raymond Debbane
Name/Title:Raymond Debbane, President
Date:02/02/2026
Avicenna Life Sci Master Fund LP
Signature:/s/ Raymond Debbane
Name/Title:Raymond Debbane, Chief Executive Officer of Avicenna Life Sci Master GP LLC, its general partner
Date:02/02/2026
Avicenna Life Sci Master GP LLC
Signature:/s/ Raymond Debbane
Name/Title:Raymond Debbane, Chief Executive Officer
Date:02/02/2026
Invus US Partners LLC
Signature:/s/ Raymond Debbane
Name/Title:Raymond Debbane, President
Date:02/02/2026
Ulys, L.L.C.
Signature:/s/ Raymond Debbane
Name/Title:Raymond Debbane, President
Date:02/02/2026
Mr. Raymond Debbane
Signature:/s/ Raymond Debbane
Name/Title:Raymond Debbane
Date:02/02/2026
Artal Participations S.a r.l.
Signature:/s/ Pierre Claudel
Name/Title:Pierre Claudel, Manager
Date:02/02/2026
Artal International S.C.A.
Signature:/s/ Anne Goffard
Name/Title:Anne Goffard, Managing Director of Artal International Management S.A., its managing partner
Date:02/02/2026
Artal International Management S.A.
Signature:/s/ Anne Goffard
Name/Title:Anne Goffard, Managing Director
Date:02/02/2026
Artal Group S.A.
Signature:/s/ Anne Goffard
Name/Title:Anne Goffard, Authorized Person
Date:02/02/2026
Westend S.A.
Signature:/s/ Anne Goffard
Name/Title:Anne Goffard, Managing Director
Date:02/02/2026
Stichting Administratiekantoor Westend
Signature:/s/ Amaury Wittouck
Name/Title:Amaury Wittouck, Sole Member of the Board
Date:02/02/2026
Mr. Amaury Wittouck
Signature:/s/ Amaury Wittouck
Name/Title:Amaury Wittouck
Date:02/02/2026

FAQ

How much of Lexicon Pharmaceuticals (LXRX) do the reporting investors now own?

The reporting investor group collectively beneficially owns about 205,952,227 shares of Lexicon common stock, or roughly 48.2% of the 427,084,567 shares outstanding. This reflects updated holdings after recent public and private financing transactions disclosed in the Schedule 13D/A amendment.

What new capital did Artal Participations commit to Lexicon Pharmaceuticals (LXRX)?

Artal Participations agreed to buy 22,400,000 Lexicon common shares for $29,120,000 and 367,145.12 shares of Series B convertible preferred stock for $23,864,432.80. These purchases were made directly from Lexicon in private placements and closed on February 2, 2026, using available funds.

What are the key terms of Lexicon’s 2026 public offering mentioned in the filing?

Lexicon entered an underwriting agreement to issue and sell 32,000,000 common shares, with underwriters holding a 30‑day option to buy up to 4,800,000 additional shares. Avicenna Life Sci Master Fund purchased 1,538,462 shares for $2,000,000.60 as part of this 2026 public offering.

How does the new Series B preferred stock convert into Lexicon (LXRX) common shares?

Each Series B preferred share will automatically convert into 50 Lexicon common shares once three conditions are met: shareholder approval of increased authorized common shares, board adoption and filing of a new charter, and completion of any required Hart‑Scott‑Rodino antitrust clearances for conversion.

What stake does Artal Participations alone report in Lexicon Pharmaceuticals (LXRX)?

Artal Participations reports being the record and beneficial owner of 154,734,327 Lexicon common shares, representing approximately 36.2% of outstanding shares. Control is attributed up the chain to Artal International, Artal International Management, Artal Group, Westend, the Stichting and ultimately to board member Amaury Wittouck.

What ownership does Invus-related entities report in Lexicon Pharmaceuticals (LXRX)?

Invus, L.P. is record owner of 35,402,689 shares and beneficial owner of 42,765,057 shares, or about 10.0% of Lexicon’s common stock. Invus Public Equities, L.P. owns 7,362,368 shares (1.7%), and Invus US Partners LLC owns 5,451,204 shares (1.3%), with upstream entities and Raymond Debbane disclaiming beneficial ownership.
Lexicon Pharmaceuticals Inc

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