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Madrigal Pharmac SEC Filings

MDGL NASDAQ

Welcome to our dedicated page for Madrigal Pharmac SEC filings (Ticker: MDGL), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.

Trying to decipher a 300-page biopharma filing packed with clinical endpoints and FDA jargon can stall even seasoned analysts. Madrigal Pharmaceuticals’ SEC documents are no exception: every 10-K details Rezdiffra’s trial design, while 8-Ks flag pivotal data releases that can move the stock overnight. If you have searched for “Madrigal Pharmaceuticals SEC filings explained simply,” you know the challenge.

Stock Titan cuts through that complexity. Our AI reads each Madrigal Pharmaceuticals quarterly earnings report 10-Q filing, highlights cash-runway updates, and links them to ongoing MAESTRO studies. Need fast context on a sudden press release? We deliver Madrigal Pharmaceuticals 8-K material events explained in plain English within minutes of EDGAR posting. Real-time alerts surface Madrigal Pharmaceuticals Form 4 insider transactions, so you can follow executive stock trades ahead of regulatory milestones. You will also find the annual report—Madrigal Pharmaceuticals annual report 10-K simplified—and an easy path to the Madrigal Pharmaceuticals proxy statement executive compensation that breaks down R&D-driven pay packages.

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Kenneth Bate, Director at Madrigal Pharmaceuticals (MDGL), reported two significant equity transactions on June 20, 2025:

  • Received 715 restricted stock units (RSUs) at $0, bringing total direct common stock ownership to 2,627 shares
  • Granted stock options to purchase 1,290 shares at an exercise price of $285.73 per share

Both the RSUs and stock options are scheduled to vest at the company's 2026 annual stockholder meeting, contingent on Bate's continued service as director. The stock options have a ten-year term, expiring on June 20, 2035. The transactions were reported via Form 4 filing, with Mardi Dier signing as attorney-in-fact on June 24, 2025.

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Madrigal Pharmaceuticals (MDGL) filed a Form 4 disclosing new equity awards to director Richard S. Levy dated 06/20/2025.

  • Levy received 715 restricted stock units (coded “A”) at no cost. The RSUs vest on the date of the 2026 annual meeting, conditional on his continued service.
  • He was also granted 1,290 stock options with a $285.73 exercise price and a 06/20/2035 expiration. These options vest 100 % at the 2026 annual meeting, subject to the same service requirement.

Following the transactions, Levy directly owns 21,197 common shares and 1,290 options. No open-market purchases or sales were reported.

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Madrigal Pharmaceuticals director Jacqualyn A. Fouse received new equity compensation grants on June 20, 2025, consisting of:

  • 203 restricted stock units (RSUs) with a $0 exercise price, bringing total direct common stock ownership to 1,097 shares
  • 366 stock options with an exercise price of $285.73 per share

Both the RSUs and stock options are scheduled to vest at the company's 2026 annual stockholder meeting, contingent on continued service as director. The stock options expire on June 20, 2035. This Form 4 filing, signed by attorney-in-fact Mardi Dier, represents standard board of director equity compensation and demonstrates continued alignment of director interests with shareholders through equity ownership.

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Baker Bros. Advisors LP and affiliated entities reported insider transactions in Madrigal Pharmaceuticals (MDGL) stock on June 20, 2025. The transactions involved:

  • Acquisition of 1,430 restricted stock units (RSUs) each by Julian C. Baker and Dr. Raymond Cheong, granted under the company's Amended 2015 Stock Plan
  • Grant of 2,580 non-qualified stock options with a strike price of $285.73, exercisable until June 20, 2035
  • Both RSUs and options will fully vest at the 2026 annual stockholder meeting, subject to continued board service

The filing details complex beneficial ownership structures through various Baker Bros. entities, including 667, L.P. and Baker Brothers Life Sciences LP. Following the transactions, the entities hold significant positions: 188,837 shares through one entity and 1,796,261 shares through another. Julian Baker and Felix Baker maintain indirect pecuniary interests through their ownership in various Baker Bros. entities, though they disclaim beneficial ownership except for their pecuniary interest.

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Director James M. Daly of Madrigal Pharmaceuticals reported significant equity compensation grants on June 20, 2025. The transactions include:

  • Acquisition of 715 restricted stock units (RSUs) at $0, vesting at the 2026 annual stockholder meeting
  • Grant of stock options to purchase 1,290 shares at an exercise price of $285.73 per share, fully vesting at the 2026 annual stockholder meeting

Following these transactions, Daly directly owns 2,627 shares of common stock and 1,290 stock options. These grants represent standard director compensation aligned with continued service through the next annual meeting. The options have a 10-year term, expiring June 20, 2035.

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Madrigal Pharmaceuticals Director Paul A. Friedman received new equity compensation on June 20, 2025, consisting of:

  • 715 restricted stock units (RSUs) granted at $0, vesting at the 2026 annual stockholder meeting
  • 1,290 stock options with strike price of $285.73, fully vesting at the 2026 annual stockholder meeting

Following these transactions, Friedman directly owns 187,164 common shares and indirectly holds 655,540 shares through SQN LLC, where he and his spouse serve as managing members. The indirect holdings include a disclaimer of beneficial ownership except for his pecuniary interest. The equity grants appear to be part of standard director compensation, with vesting tied to continued service through the next annual meeting.

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Madrigal Pharmaceuticals has filed a Form S-8 registration statement to register 100,000 shares of common stock under its newly adopted 2025 Inducement Stock Plan. The plan, adopted by the Board on June 16, 2025, is designed to provide equity incentives to new employees as inducement awards under Nasdaq Listing Rule 5635(c)(4).

Key details of the registration:

  • The plan allows for various types of awards including stock options, restricted stock, RSUs, and performance stock awards
  • Only individuals who qualify under Nasdaq inducement grant standards are eligible
  • The plan was adopted without stockholder approval, as permitted under Nasdaq rules
  • The Compensation Committee will administer the plan

The company is classified as a large accelerated filer and has incorporated by reference its recent SEC filings, including its 2024 Annual Report, Q1 2025 quarterly report, and recent Form 8-K filings. The registration includes standard indemnification provisions for directors and officers.

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Madrigal Pharmaceuticals held its 2025 Annual Meeting of Stockholders on June 20, 2025, with 20,427,421 shares represented (92% of outstanding shares), constituting a quorum. Key outcomes include:

  • Board Elections: Four Class III directors were re-elected to serve until 2028, including Julian Baker, Dr. Raymond Cheong, Dr. Jacqualyn Fouse, and Dr. Richard Levy, with Dr. Fouse receiving the highest approval (18.8M votes)
  • Auditor Appointment: Stockholders ratified PricewaterhouseCoopers LLP as independent auditor with overwhelming support (20.2M votes in favor)
  • Executive Compensation: Shareholders approved named executive officers' compensation with strong support (18.7M votes in favor)
  • Say-on-Pay Frequency: Stockholders strongly favored annual advisory votes on executive compensation (18.8M votes), which the Board has adopted
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FAQ

What is the current stock price of Madrigal Pharmac (MDGL)?

The current stock price of Madrigal Pharmac (MDGL) is $302.64 as of June 30, 2025.

What is the market cap of Madrigal Pharmac (MDGL)?

The market cap of Madrigal Pharmac (MDGL) is approximately 6.3B.

What is the core focus of Madrigal Pharmaceuticals?

Madrigal Pharmaceuticals is focused on developing novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease with high unmet medical need.

What is Rezdiffra and how does it work?

Rezdiffra is an oral, once-daily, liver-directed THR-β agonist designed to address the underlying causes of MASH by improving fibrosis and resolving steatohepatitis.

How does Madrigal demonstrate its clinical and scientific expertise?

The company employs rigorous Phase 3 clinical trials, integrates AI-driven analyses, and publishes results in respected medical journals to validate the efficacy and safety of its therapeutics.

What sets Madrigal apart in the competitive landscape?

Madrigal differentiates itself by focusing on both the symptomatic and underlying metabolic drivers of MASH, using innovative research and robust patient support programs to enhance treatment outcomes.

How does the company support patient access to its therapy?

Madrigal has established comprehensive patient support and assistance programs to help individuals navigate insurance and affordability challenges, ensuring broader access to Rezdiffra.

What regulatory milestones has Madrigal achieved?

Madrigal has secured critical regulatory approvals, including FDA accelerated approval for Rezdiffra, based on extensive clinical trial data and robust evidence demonstrating its therapeutic benefits.

What future research directions is Madrigal pursuing?

The company continues to invest in further research to optimize clinical outcomes, explore additional therapeutic indications, and refine its understanding of MASH pathophysiology through advanced biomarker and imaging studies.

How does Madrigal contribute to the broader understanding of liver disease?

By combining deep scientific research with innovative clinical trials and patient support initiatives, Madrigal enhances the overall treatment paradigm for liver diseases, offering new insights into managing MASH and related conditions.
Madrigal Pharmac

NASDAQ:MDGL

MDGL Rankings

MDGL Stock Data

6.28B
20.42M
8.74%
105.1%
17%
Biotechnology
Pharmaceutical Preparations
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United States
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