[Form 4] MeiraGTx Holdings plc Insider Trading Activity

Rhea-AI Filing Summary

MeiraGTx Holdings plc (MGTX) – Form 4 insider transaction

President & CEO Alexandria Forbes reported the sale of 47,500 ordinary shares of MGTX on 8 July 2025. The shares were disposed of at a weighted-average price of $7.97 per share (individual trade prices ranged from $7.73 to $8.15). The transaction was executed under a Rule 10b5-1 trading plan adopted 21 Aug 2024, indicating it was pre-scheduled and not the result of ad-hoc decision-making.

Following the sale, Forbes’ direct beneficial ownership stands at 1,361,483 ordinary shares. No derivative securities were involved in this filing, and no additional transactions were reported.

The gross proceeds of the reported sale, based on the disclosed weighted-average price, total roughly $379 thousand. Forbes continues to serve as both Director and President & CEO of MeiraGTx.

Positive

• Transaction executed under an established Rule 10b5-1 plan, indicating advance compliance and reducing concerns about opportunistic trading.
• CEO retains 1,361,483 shares, maintaining a substantial equity stake that aligns management incentives with shareholders.

Negative

• Insider sale of 47,500 shares by the CEO can be viewed as a mild negative sentiment indicator.
• No offsetting insider purchases or new derivative grants were disclosed, offering no positive counter-signal.

Insights

Securities Analyst

TL;DR: CEO sells ~47.5k shares (~$0.38m) via 10b5-1 plan; retains 1.36 m shares – modestly negative signal.

The filing shows routine diversification rather than wholesale exit. A disposal of 47,500 shares represents a small portion of Forbes’ holding, leaving her with over 1.36 million shares. Execution under a previously adopted Rule 10b5-1 plan reduces concerns of opportunistic timing. Nevertheless, any insider sale—especially by the CEO—can be interpreted as a slight negative sentiment indicator. Absent complementary information such as earnings or guidance, market impact should be limited.

Corporate Governance Specialist

TL;DR: Pre-planned sale limits governance risk; insider still holds significant stake.

Compliance appears strong: the 10b5-1 plan was in place well in advance, and full price-range disclosure is provided. With ~1.36 million shares remaining, alignment between management and shareholders is preserved. The transaction does not suggest a shift in strategic posture or control. Overall governance impact is neutral.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

X

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Forbes Alexandria

(Last) (First) (Middle)

450 EAST 29TH STREET

14TH FLOOR

(Street)

NEW YORK NY 10016

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
MeiraGTx Holdings plc [ MGTX ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	PRESIDENT & CEO

3. Date of Earliest Transaction (Month/Day/Year)
07/08/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Ordinary Shares	07/08/2025		S(1)		47,500	D	$7.97(2)(3)	1,361,483	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 21, 2024.

2. The price reported reflects the weighted average sales price. The shares were sold in multiple transactions at prices ranging from $7.73 to $8.15, inclusive.

3. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price.

	/s/ Richard Giroux, Attorney-in-Fact for Alexandria Forbes	07/08/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

How many MGTX shares did CEO Alexandria Forbes sell on 8 July 2025?

She sold 47,500 ordinary shares.

At what price range were the MGTX shares sold?

Sales were executed between $7.73 and $8.15 with a weighted-average of $7.97.

Is the transaction part of a Rule 10b5-1 trading plan?

Yes. The filing states the sales were made under a 10b5-1 plan adopted on 21 Aug 2024.

How many MGTX shares does the CEO still own after the sale?

Alexandria Forbes now directly owns 1,361,483 ordinary shares.

Were any derivative securities involved in this Form 4 filing?

No. No options, warrants, or other derivatives were reported.