STOCK TITAN

[Form 4] Mirum Pharmaceuticals, Inc. Insider Trading Activity

Filing Impact
(High)
Filing Sentiment
(Negative)
Form Type
4
Rhea-AI Filing Summary

Jolanda Howe, SVP, Global Controller of Mirum Pharmaceuticals (MIRM), reported both non-derivative and derivative transactions affecting her holdings. The filing shows a sale of 10,000 common shares at $58.00, after which her reported direct beneficial ownership stood at 2,426 shares. On the same date she recorded an acquisition-related entry at a $6.27 price for 10,000 common shares, with a reported beneficial ownership figure of 12,426 shares following that transaction.

An employee stock option with a conversion/exercise price of $6.27 covering 10,000 underlying shares is reported and is stated to be fully vested. The filing notes the sale was executed pursuant to a Rule 10b5-1 plan adopted December 16, 2024, and the reporting person is shown as beneficial owner of 40,000 derivative securities following the reported activity.

Jolanda Howe, SVP, Global Controller di Mirum Pharmaceuticals (MIRM), ha segnalato operazioni sia su titoli non derivati sia su strumenti derivati che hanno interessato le sue partecipazioni. La comunicazione indica una vendita di 10,000 azioni ordinarie a $58.00, dopo la quale la sua proprietà diretta beneficiaria risultava di 2,426 azioni. Nello stesso giorno ha registrato una voce d'acquisto relativa a 10,000 azioni ordinarie al prezzo di $6.27, con una proprietà beneficiaria riportata di 12,426 azioni a seguito di tale operazione.

Risulta inoltre un'opzione su azioni per dipendenti con prezzo di conversione/esercizio di $6.27 relativa a 10,000 azioni sottostanti, dichiarata completamente maturata. La comunicazione precisa che la vendita è stata eseguita in base a un piano Rule 10b5-1 adottato il 16 dicembre 2024, e la persona che ha effettuato la segnalazione risulta beneficiaria di 40,000 strumenti derivati dopo l'operazione segnalata.

Jolanda Howe, SVP y Controladora Global de Mirum Pharmaceuticals (MIRM), informó transacciones tanto no derivadas como derivadas que afectaron sus participaciones. La presentación muestra una venta de 10,000 acciones ordinarias a $58.00, tras la cual su tenencia directa beneficiaria reportada quedó en 2,426 acciones. En la misma fecha registró una anotación por adquisición de 10,000 acciones ordinarias a un precio de $6.27, con una tenencia beneficiaria informada de 12,426 acciones después de esa operación.

Se reporta además una opción sobre acciones de empleados con precio de conversión/ejercicio de $6.27 que cubre 10,000 acciones subyacentes y que se indica está totalmente adquirida. La presentación señala que la venta se ejecutó conforme a un plan Rule 10b5-1 adoptado el 16 de diciembre de 2024, y la persona informante figura como titular beneficiaria de 40,000 valores derivados tras la actividad informada.

Jolanda Howe는 Mirum Pharmaceuticals (MIRM)의 SVP 겸 Global Controller로서 자신의 보유분에 영향을 미친 비파생 및 파생 거래를 모두 신고했습니다. 제출서류에는 10,000 보통주를 주당 $58.00에 매도한 내용이 기재되어 있으며, 그 후 신고된 직접 실소유 지분은 2,426주였습니다. 같은 날 그녀는 10,000 보통주를 주당 $6.27에 취득한 항목을 기록했고, 해당 거래 이후 신고된 실소유 지분은 12,426주로 보고되었습니다.

행사/전환 가격이 $6.27인 직원 주식옵션(기초주식 10,000주)이 보고되어 있으며, 해당 옵션은 완전히 베스팅(완전 취득)된 것으로 명시되어 있습니다. 제출서류는 매도 거래가 2024년 12월 16일 채택된 Rule 10b5-1 플랜에 따라 실행되었음을 밝히고 있으며, 해당 신고인은 보고된 거래 이후 40,000개의 파생증권에 대한 실질적 소유주로 표시되어 있습니다.

Jolanda Howe, vice-présidente senior et contrôleuse financière mondiale de Mirum Pharmaceuticals (MIRM), a déclaré des opérations à la fois non dérivées et dérivées affectant ses participations. Le dépôt indique une vente de 10 000 actions ordinaires au prix de 58,00 $, après quoi sa détention directe déclarée s’élevait à 2 426 actions. Le même jour, elle a enregistré une opération d’acquisition de 10 000 actions ordinaires au prix de 6,27 $, portant sa détention bénéficiaire déclarée à 12 426 actions à la suite de cette transaction.

Une option sur actions d’employé au prix de conversion/exercice de 6,27 $ portant sur 10 000 actions sous-jacentes est également signalée et est indiquée comme entièrement acquise. Le dépôt précise que la vente a été exécutée conformément à un plan Rule 10b5-1 adopté le 16 décembre 2024, et que la personne déclarant la transaction est indiquée comme propriétaire bénéficiaire de 40 000 produits dérivés après l’activité signalée.

Jolanda Howe, Senior Vice President und Global Controller von Mirum Pharmaceuticals (MIRM), meldete sowohl Nicht-Derivat- als auch Derivat-Transaktionen, die ihre Bestände betrafen. Die Meldung zeigt einen Verkauf von 10.000 Stammaktien zum Preis von $58.00, wonach ihr gemeldetes direktes wirtschaftliches Eigentum 2.426 Aktien betrug. Am selben Tag verzeichnete sie einen Erwerbs-Eintrag über 10.000 Stammaktien zum Preis von $6.27, sodass nach dieser Transaktion ein gemeldetes wirtschaftliches Eigentum von 12.426 Aktien angegeben wurde.

Berichtet wird außerdem eine Mitarbeiter-Aktienoption mit einem Umwandlungs/Optionspreis von $6.27 für 10.000 zugrunde liegende Aktien, die als vollständig unverfallbar angegeben ist. Die Meldung weist darauf hin, dass der Verkauf im Rahmen eines am 16. Dezember 2024 verabschiedeten Rule 10b5-1 Plans ausgeführt wurde, und die meldende Person wird nach der gemeldeten Transaktion als wirtschaftliche Eigentümerin von 40.000 Derivaten geführt.

Positive
  • Transactions executed under a Rule 10b5-1 plan, indicating pre-arranged trading instructions
  • Employee stock option is fully vested, covering 10,000 underlying shares
Negative
  • Sale of 10,000 shares at $58.00 reduced direct beneficial ownership to 2,426 shares
  • Direct holdings now modest (reported direct ownership of 2,426 shares) after the reported disposition

Insights

TL;DR: Insider exercised vested options and executed a 10b5-1 sale; direct holdings fell while derivative exposure remains sizable.

The report shows two principal actions: a disposition of 10,000 common shares at $58.00 and acquisition-related activity tied to a $6.27 price for 10,000 shares. The filing also documents a fully vested employee stock option covering 10,000 underlying shares and indicates 40,000 derivative securities are beneficially owned after the activity. Because the sale was executed under a documented Rule 10b5-1 plan, the transactions reflect pre-arranged activity rather than an ad hoc market sale. For investors, the net change alters direct ownership levels but leaves meaningful derivative exposure.

TL;DR: Transactions were carried out under a 10b5-1 plan and involve a fully vested option, indicating planned execution and vested equity compensation.

The Form 4 discloses that the reporting person executed transactions pursuant to a Rule 10b5-1 plan adopted December 16, 2024, and that an employee stock option is fully vested. Those facts are relevant for governance and disclosure: the 10b5-1 plan provides an affirmative defense for trades made under the plan, and vesting status clarifies the reporting person’s ability to exercise or transfer option-derived shares. The filing is procedural and compliant in nature; it documents planned insider activity rather than new corporate events.

Jolanda Howe, SVP, Global Controller di Mirum Pharmaceuticals (MIRM), ha segnalato operazioni sia su titoli non derivati sia su strumenti derivati che hanno interessato le sue partecipazioni. La comunicazione indica una vendita di 10,000 azioni ordinarie a $58.00, dopo la quale la sua proprietà diretta beneficiaria risultava di 2,426 azioni. Nello stesso giorno ha registrato una voce d'acquisto relativa a 10,000 azioni ordinarie al prezzo di $6.27, con una proprietà beneficiaria riportata di 12,426 azioni a seguito di tale operazione.

Risulta inoltre un'opzione su azioni per dipendenti con prezzo di conversione/esercizio di $6.27 relativa a 10,000 azioni sottostanti, dichiarata completamente maturata. La comunicazione precisa che la vendita è stata eseguita in base a un piano Rule 10b5-1 adottato il 16 dicembre 2024, e la persona che ha effettuato la segnalazione risulta beneficiaria di 40,000 strumenti derivati dopo l'operazione segnalata.

Jolanda Howe, SVP y Controladora Global de Mirum Pharmaceuticals (MIRM), informó transacciones tanto no derivadas como derivadas que afectaron sus participaciones. La presentación muestra una venta de 10,000 acciones ordinarias a $58.00, tras la cual su tenencia directa beneficiaria reportada quedó en 2,426 acciones. En la misma fecha registró una anotación por adquisición de 10,000 acciones ordinarias a un precio de $6.27, con una tenencia beneficiaria informada de 12,426 acciones después de esa operación.

Se reporta además una opción sobre acciones de empleados con precio de conversión/ejercicio de $6.27 que cubre 10,000 acciones subyacentes y que se indica está totalmente adquirida. La presentación señala que la venta se ejecutó conforme a un plan Rule 10b5-1 adoptado el 16 de diciembre de 2024, y la persona informante figura como titular beneficiaria de 40,000 valores derivados tras la actividad informada.

Jolanda Howe는 Mirum Pharmaceuticals (MIRM)의 SVP 겸 Global Controller로서 자신의 보유분에 영향을 미친 비파생 및 파생 거래를 모두 신고했습니다. 제출서류에는 10,000 보통주를 주당 $58.00에 매도한 내용이 기재되어 있으며, 그 후 신고된 직접 실소유 지분은 2,426주였습니다. 같은 날 그녀는 10,000 보통주를 주당 $6.27에 취득한 항목을 기록했고, 해당 거래 이후 신고된 실소유 지분은 12,426주로 보고되었습니다.

행사/전환 가격이 $6.27인 직원 주식옵션(기초주식 10,000주)이 보고되어 있으며, 해당 옵션은 완전히 베스팅(완전 취득)된 것으로 명시되어 있습니다. 제출서류는 매도 거래가 2024년 12월 16일 채택된 Rule 10b5-1 플랜에 따라 실행되었음을 밝히고 있으며, 해당 신고인은 보고된 거래 이후 40,000개의 파생증권에 대한 실질적 소유주로 표시되어 있습니다.

Jolanda Howe, vice-présidente senior et contrôleuse financière mondiale de Mirum Pharmaceuticals (MIRM), a déclaré des opérations à la fois non dérivées et dérivées affectant ses participations. Le dépôt indique une vente de 10 000 actions ordinaires au prix de 58,00 $, après quoi sa détention directe déclarée s’élevait à 2 426 actions. Le même jour, elle a enregistré une opération d’acquisition de 10 000 actions ordinaires au prix de 6,27 $, portant sa détention bénéficiaire déclarée à 12 426 actions à la suite de cette transaction.

Une option sur actions d’employé au prix de conversion/exercice de 6,27 $ portant sur 10 000 actions sous-jacentes est également signalée et est indiquée comme entièrement acquise. Le dépôt précise que la vente a été exécutée conformément à un plan Rule 10b5-1 adopté le 16 décembre 2024, et que la personne déclarant la transaction est indiquée comme propriétaire bénéficiaire de 40 000 produits dérivés après l’activité signalée.

Jolanda Howe, Senior Vice President und Global Controller von Mirum Pharmaceuticals (MIRM), meldete sowohl Nicht-Derivat- als auch Derivat-Transaktionen, die ihre Bestände betrafen. Die Meldung zeigt einen Verkauf von 10.000 Stammaktien zum Preis von $58.00, wonach ihr gemeldetes direktes wirtschaftliches Eigentum 2.426 Aktien betrug. Am selben Tag verzeichnete sie einen Erwerbs-Eintrag über 10.000 Stammaktien zum Preis von $6.27, sodass nach dieser Transaktion ein gemeldetes wirtschaftliches Eigentum von 12.426 Aktien angegeben wurde.

Berichtet wird außerdem eine Mitarbeiter-Aktienoption mit einem Umwandlungs/Optionspreis von $6.27 für 10.000 zugrunde liegende Aktien, die als vollständig unverfallbar angegeben ist. Die Meldung weist darauf hin, dass der Verkauf im Rahmen eines am 16. Dezember 2024 verabschiedeten Rule 10b5-1 Plans ausgeführt wurde, und die meldende Person wird nach der gemeldeten Transaktion als wirtschaftliche Eigentümerin von 40.000 Derivaten geführt.

SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Estimated average burden
hours per response: 0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Howe Jolanda

(Last) (First) (Middle)
C/O MIRUM PHARMACEUTICALS, INC.
989 E HILLSDALE BLVD., SUITE 300

(Street)
FOSTER CITY CA 94404

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
Mirum Pharmaceuticals, Inc. [ MIRM ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director 10% Owner
X Officer (give title below) Other (specify below)
SVP, GLOBAL CONTROLLER
3. Date of Earliest Transaction (Month/Day/Year)
08/07/2025
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 08/07/2025 M 10,000 A $6.27 12,426 D
Common Stock 08/07/2025 S(1) 10,000 D $58 2,426 D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Employee Stock Option (right to buy) $6.27 08/07/2025 M 10,000 (2) 05/13/2029 Common Stock 10,000 $0 40,000 D
Explanation of Responses:
1. Reported transaction occurred pursuant to a Rule 10b5-1 Plan adopted by the reporting person on December 16, 2024.
2. The stock option is fully vested.
/s/ Judit Ryvkin, Attorney-in-Fact 08/08/2025
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What insider activity did Mirum (MIRM) report on this Form 4?

The Form 4 reports a sale of 10,000 common shares at $58.00 and acquisition-related activity for 10,000 shares at $6.27, plus derivative reporting.

Who is the reporting person on the Form 4 for MIRM?

The reporting person is Jolanda Howe, listed as SVP, Global Controller of Mirum Pharmaceuticals.

When were the reported transactions executed?

The transactions are reported with a transaction date of 08/07/2025.

Were the trades part of a trading plan?

Yes. The filing states the sale occurred pursuant to a Rule 10b5-1 plan adopted on December 16, 2024.

How many derivative securities does the reporting person beneficially own after the transactions?

The filing shows 40,000 derivative securities beneficially owned following the reported transactions.

Is the reported stock option vested?

Yes. The Form 4 explicitly states the stock option is fully vested.
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Biotechnology
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United States
FOSTER CITY