Mirum Pharma SVP sells 40,000 shares after option exercise

Mirum Pharmaceuticals, Inc. (MIRM) reported insider equity transactions by Jolanda Howe, its SVP, Global Controller.

Rhea-AI Filing Summary

Mirum Pharmaceuticals, Inc. (MIRM) reported insider equity transactions by Jolanda Howe, its SVP, Global Controller. On 2026-08-18, Howe exercised 40,000 employee stock options at an exercise price of $6.27 per share, acquiring an equal number of common shares. On the same date, she sold 40,000 common shares at $100.00 per share in a transaction described as a sale in an open market or private transaction. The option grant was fully vested at the time of exercise, and the option position reported in this filing was reduced to zero.

Insider Trade Summary

Exercise and Sale: 40,000 shares ($3.75M approx. pre-tax spread)

Exercise and Sale 3 txns

Insider Howe Jolanda

Role SVP, GLOBAL CONTROLLER

Sold 40,000 shs ($4.00M)

Approx. gross sale proceeds $4.00M

Approx. exercise cost $251K

Approx. pre-tax spread $3.75M

Type	Security	Shares	Price	Value
Exercise	Employee Stock Option (right to buy) F1	40,000	$0.00	$0.00
Exercise	Common Stock	40,000	$6.27	$251K
Sale	Common Stock	40,000	$100.00	$4.00M

Holdings After Transaction: Employee Stock Option (right to buy) — 0 contracts (Direct); Common Stock — 1,274 shares (Direct)

Footnotes (1)

1. F1. The stock option is fully vested.

Key Figures

Options Exercised: 40,000 shares Exercise Price: $6.27 per share Shares Sold: 40,000 shares +2 more

5 metrics

Options Exercised 40,000 shares Employee stock options exercised by Jolanda Howe on 2026-08-18

Exercise Price $6.27 per share Exercise price of employee stock options exercised on 2026-08-18

Shares Sold 40,000 shares Mirum common stock sold by Jolanda Howe on 2026-08-18

Sale Price $100.00 per share Per-share price for sale of common stock on 2026-08-18

Options Remaining from Grant 0 shares Total shares underlying the reported stock option following exercise

Key Terms

Employee Stock Option, derivative security, open market or private transaction

3 terms

Employee Stock Option financial

"security_title: "Employee Stock Option (right to buy)""

An employee stock option is a promise that lets a worker buy company shares later at a predetermined price, often after they stay for a certain period or meet performance goals — think of it like a coupon that locks in today's price for a future purchase. It matters to investors because options align employees’ incentives with company performance, can increase the number of shares outstanding (dilution) when exercised, and represent a compensation cost that affects reported profits and shareholder value.

derivative security financial

"transaction_action: "derivative exercise/conversion""

A derivative security is a financial contract whose value comes from the price or performance of something else, such as a stock, bond, commodity, or market index. For investors it acts like an insurance policy or a wager: it can be used to protect against losses, lock in prices, or amplify gains and losses, so it can change a portfolio’s risk and potential return without owning the underlying asset directly.

open market or private transaction financial

"transaction_code_description: "Sale in open market or private transaction""

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What insider transaction did Mirum Pharmaceuticals (MIRM) report for Jolanda Howe?

Mirum Pharmaceuticals reported that Jolanda Howe exercised 40,000 stock options and sold 40,000 common shares on 2026-08-18. The transactions involved exercising options at $6.27 per share and selling the resulting shares at $100.00 per share.

How many Mirum Pharmaceuticals (MIRM) options did Jolanda Howe exercise?

Jolanda Howe exercised 40,000 employee stock options in Mirum Pharmaceuticals. These options had an exercise price of $6.27 per share and were fully vested, resulting in the acquisition of 40,000 Mirum common shares before the same-day sale.

At what prices were Jolanda Howe’s Mirum (MIRM) transactions executed?

Jolanda Howe exercised options at an exercise price of $6.27 per share and sold the resulting Mirum common shares at $100.00 per share. Both transactions occurred on 2026-08-18, according to the Form 4 data.

What happened to Jolanda Howe’s Mirum (MIRM) stock option position after the transactions?

Following the reported transactions, the stock option position associated with the 40,000 options was reduced to 0 shares. The Form 4 shows no remaining holdings for that specific option grant after the 2026-08-18 exercise.

Were Jolanda Howe’s Mirum (MIRM) trades under a Rule 10b5-1 plan?

The filing indicates the Rule 10b5-1 checkbox was not affirmed for these transactions. There is no footnote stating that the 2026-08-18 exercise and sale were made pursuant to a pre-arranged Rule 10b5-1 trading plan.

AI-generated analysis. How Rhea-AI works. Not financial advice.

Form 4 Insider Transactions: What Each Field Means →

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Available on EDGAR 08/19/2026 - 06:20 PM Accepted by SEC EDGAR 08/19/2026 - 06:19 PM Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Howe Jolanda

(Last) (First) (Middle)

C/O MIRUM PHARMACEUTICALS, INC.

989 E HILLSDALE BLVD., SUITE 300

(Street)

FOSTER CITY CALIFORNIA 94404

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
Mirum Pharmaceuticals, Inc. [ MIRM ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	SVP, GLOBAL CONTROLLER

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
08/18/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	08/18/2026		M		40,000	A	$6.27	41,274	D
Common Stock	08/18/2026		S		40,000	D	$100	1,274	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Employee Stock Option (right to buy)	$6.27	08/18/2026		M			40,000	(1)	05/13/2029	Common Stock	40,000	$0	0	D

Explanation of Responses:

1. The stock option is fully vested.

	/s/ Judit Ryvkin, Attorney-in-Fact	08/19/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)