STOCK TITAN

Frazier Life Sciences boosts Mirum (NASDAQ: MIRM) stake and gains resale rights

Filing Impact
(Moderate)
Filing Sentiment
(Neutral)
Form Type
SCHEDULE 13D/A

Rhea-AI Filing Summary

Frazier Life Sciences-affiliated funds and managers have updated their ownership disclosures in Mirum Pharmaceuticals, Inc. (MIRM) through Amendment No. 8 to a Schedule 13D. The filing shows Frazier Life Sciences IX, L.P. holding 3,566,912 shares of common stock, representing 5.9% of the class, and Frazier Life Sciences X, L.P. holding 459,010 shares, or 0.8%. Frazier Life Sciences Public Fund, L.P. holds 2,514,947 shares, or 4.2%, while other Frazier funds hold smaller stakes.

The filing attributes 4,025,922 shares, or 6.7% of the class, to James N. Topper through shared voting and investment power over certain funds, and 4,108,404 shares, or 6.8%, to Patrick J. Heron, including 76,779 option shares. The investors state the shares were acquired for investment purposes and that they have no present plans for mergers, control changes, or other major corporate actions. A registration rights agreement dated December 7, 2025 entitles several Frazier funds to have Mirum register for resale both their common shares and shares underlying pre-funded warrants purchased on January 23, 2026, including warrants held by the public fund subject to a 9.99% beneficial ownership cap.

Positive

  • None.

Negative

  • None.





If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box.

The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).






SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on the sum of (i) 51,393,574 shares of Common Stock outstanding on October 31, 2025 as set forth in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on November 4, 2025, (ii) 5,196,009 shares of Common Stock that were anticipated to be issued in connection with the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, (iii) 2,385,149 shares of Common Stock that were anticipated to be issued by the Issuer in a private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, and (iv) 1,000,000 shares of Common Stock that were anticipated to be issued by the Issuer in an additional private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 19, 2025.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on the sum of (i) 51,393,574 shares of Common Stock outstanding on October 31, 2025 as set forth in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on November 4, 2025, (ii) 5,196,009 shares of Common Stock that were anticipated to be issued in connection with the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, (iii) 2,385,149 shares of Common Stock that were anticipated to be issued by the Issuer in a private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, and (iv) 1,000,000 shares of Common Stock that were anticipated to be issued by the Issuer in an additional private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 19, 2025.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on the sum of (i) 51,393,574 shares of Common Stock outstanding on October 31, 2025 as set forth in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on November 4, 2025, (ii) 5,196,009 shares of Common Stock that were anticipated to be issued in connection with the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, (iii) 2,385,149 shares of Common Stock that were anticipated to be issued by the Issuer in a private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, and (iv) 1,000,000 shares of Common Stock that were anticipated to be issued by the Issuer in an additional private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 19, 2025.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on the sum of (i) 51,393,574 shares of Common Stock outstanding on October 31, 2025 as set forth in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on November 4, 2025, (ii) 5,196,009 shares of Common Stock that were anticipated to be issued in connection with the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, (iii) 2,385,149 shares of Common Stock that were anticipated to be issued by the Issuer in a private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, and (iv) 1,000,000 shares of Common Stock that were anticipated to be issued by the Issuer in an additional private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 19, 2025.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on the sum of (i) 51,393,574 shares of Common Stock outstanding on October 31, 2025 as set forth in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on November 4, 2025, (ii) 5,196,009 shares of Common Stock that were anticipated to be issued in connection with the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, (iii) 2,385,149 shares of Common Stock that were anticipated to be issued by the Issuer in a private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, and (iv) 1,000,000 shares of Common Stock that were anticipated to be issued by the Issuer in an additional private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 19, 2025.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on the sum of (i) 51,393,574 shares of Common Stock outstanding on October 31, 2025 as set forth in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on November 4, 2025, (ii) 5,196,009 shares of Common Stock that were anticipated to be issued in connection with the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, (iii) 2,385,149 shares of Common Stock that were anticipated to be issued by the Issuer in a private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, and (iv) 1,000,000 shares of Common Stock that were anticipated to be issued by the Issuer in an additional private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 19, 2025.


SCHEDULE 13D




Comment for Type of Reporting Person:
The amounts reported in rows 8, 10 and 11 represent shares held by the Reporting Person and do not include any warrants held by the Reporting Person. See Item 5(a) to this Statement. The percentage listed in row 13 is calculated based on the sum of (i) 51,393,574 shares of Common Stock outstanding on October 31, 2025 as set forth in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on November 4, 2025, (ii) 5,196,009 shares of Common Stock that were anticipated to be issued in connection with the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, (iii) 2,385,149 shares of Common Stock that were anticipated to be issued by the Issuer in a private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, and (iv) 1,000,000 shares of Common Stock that were anticipated to be issued by the Issuer in an additional private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 19, 2025.


SCHEDULE 13D




Comment for Type of Reporting Person:
The amounts reported in rows 8, 10 and 11 represent shares held by the Reporting Person and do not include any warrants held by the Reporting Person. See Item 5(a) to this Statement. The percentage listed in row 13 is calculated based on the sum of (i) 51,393,574 shares of Common Stock outstanding on October 31, 2025 as set forth in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on November 4, 2025, (ii) 5,196,009 shares of Common Stock that were anticipated to be issued in connection with the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, (iii) 2,385,149 shares of Common Stock that were anticipated to be issued by the Issuer in a private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, and (iv) 1,000,000 shares of Common Stock that were anticipated to be issued by the Issuer in an additional private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 19, 2025.


SCHEDULE 13D




Comment for Type of Reporting Person:
The amounts reported in rows 8, 10 and 11 represent shares held by the Reporting Person and do not include any warrants held by the Reporting Person. See Item 5(a) to this Statement. The percentage listed in row 13 is calculated based on the sum of (i) 51,393,574 shares of Common Stock outstanding on October 31, 2025 as set forth in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on November 4, 2025, (ii) 5,196,009 shares of Common Stock that were anticipated to be issued in connection with the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, (iii) 2,385,149 shares of Common Stock that were anticipated to be issued by the Issuer in a private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, and (iv) 1,000,000 shares of Common Stock that were anticipated to be issued by the Issuer in an additional private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 19, 2025.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on the sum of (i) 51,393,574 shares of Common Stock outstanding on October 31, 2025 as set forth in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on November 4, 2025, (ii) 5,196,009 shares of Common Stock that were anticipated to be issued in connection with the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, (iii) 2,385,149 shares of Common Stock that were anticipated to be issued by the Issuer in a private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, and (iv) 1,000,000 shares of Common Stock that were anticipated to be issued by the Issuer in an additional private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 19, 2025.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on the sum of (i) 51,393,574 shares of Common Stock outstanding on October 31, 2025 as set forth in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on November 4, 2025, (ii) 5,196,009 shares of Common Stock that were anticipated to be issued in connection with the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, (iii) 2,385,149 shares of Common Stock that were anticipated to be issued by the Issuer in a private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, and (iv) 1,000,000 shares of Common Stock that were anticipated to be issued by the Issuer in an additional private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 19, 2025.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on the sum of (i) 51,393,574 shares of Common Stock outstanding on October 31, 2025 as set forth in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on November 4, 2025, (ii) 5,196,009 shares of Common Stock that were anticipated to be issued in connection with the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, (iii) 2,385,149 shares of Common Stock that were anticipated to be issued by the Issuer in a private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, and (iv) 1,000,000 shares of Common Stock that were anticipated to be issued by the Issuer in an additional private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 19, 2025.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on the sum of (i) 51,393,574 shares of Common Stock outstanding on October 31, 2025 as set forth in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on November 4, 2025, (ii) 5,196,009 shares of Common Stock that were anticipated to be issued in connection with the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, (iii) 2,385,149 shares of Common Stock that were anticipated to be issued by the Issuer in a private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, and (iv) 1,000,000 shares of Common Stock that were anticipated to be issued by the Issuer in an additional private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 19, 2025.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on the sum of (i) 51,393,574 shares of Common Stock outstanding on October 31, 2025 as set forth in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on November 4, 2025, (ii) 5,196,009 shares of Common Stock that were anticipated to be issued in connection with the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, (iii) 2,385,149 shares of Common Stock that were anticipated to be issued by the Issuer in a private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, and (iv) 1,000,000 shares of Common Stock that were anticipated to be issued by the Issuer in an additional private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 19, 2025.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on the sum of (i) 51,393,574 shares of Common Stock outstanding on October 31, 2025 as set forth in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on November 4, 2025, (ii) 5,196,009 shares of Common Stock that were anticipated to be issued in connection with the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, (iii) 2,385,149 shares of Common Stock that were anticipated to be issued by the Issuer in a private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, and (iv) 1,000,000 shares of Common Stock that were anticipated to be issued by the Issuer in an additional private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 19, 2025.


SCHEDULE 13D




Comment for Type of Reporting Person:
The shares listed in rows 8, 10 and 11 represents (i) 3,566,912 shares of Common Stock held directly by Frazier Life Sciences IX, L.P., and (ii) 459,010 shares of Common Stock held directly by Frazier Life Sciences X, L.P. The percentage listed in row 13 is calculated based on the sum of (i) 51,393,574 shares of Common Stock outstanding on October 31, 2025 as set forth in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on November 4, 2025, (ii) 5,196,009 shares of Common Stock that were anticipated to be issued in connection with the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, (iii) 2,385,149 shares of Common Stock that were anticipated to be issued by the Issuer in a private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, and (iv) 1,000,000 shares of Common Stock that were anticipated to be issued by the Issuer in an additional private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 19, 2025.


SCHEDULE 13D




Comment for Type of Reporting Person:
The shares listed in rows 8, 10 and 11 represents (i) 5,703 shares of Common Stock held directly by the Reporting Person, (ii) 76,779 shares of Common Stock that are issuable upon the exercise of options held directly by the Reporting Person, (iii) 3,566,912 shares of Common Stock held directly by Frazier Life Sciences IX, L.P., and (iv) 459,010 shares of Common Stock held directly by Frazier Life Sciences X, L.P. The percentage listed in row 13 is calculated based on the sum of (i) 51,393,574 shares of Common Stock outstanding on October 31, 2025 as set forth in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on November 4, 2025, (ii) 5,196,009 shares of Common Stock that were anticipated to be issued in connection with the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, (iii) 2,385,149 shares of Common Stock that were anticipated to be issued by the Issuer in a private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 8, 2025, (iv) 1,000,000 shares of Common Stock that were anticipated to be issued by the Issuer in an additional private placement transaction immediately following the acquisition of Bluejay Therapeutics, Inc., as set forth in the Issuer's Current Report on Form 8-K filed with the SEC on December 19, 2025, and (v) 76,779 shares of Common Stock that are issuable upon the exercise of options held directly by the Reporting Person.


SCHEDULE 13D


Frazier Life Sciences IX, L.P.
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS IX, L.L.C., GP of FHMLS IX, L.P., GP of Frazier Life Sciences IX, L.P.
Date:01/27/2026
FHMLS IX, L.P.
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS IX, L.L.C., GP of FHMLS IX, L.P.
Date:01/27/2026
FHMLS IX, L.L.C.
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS IX, L.L.C.
Date:01/27/2026
Frazier Life Sciences X, L.P.
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS X, L.L.C., GP of FHMLS X, L.P., GP of Frazier Life Sciences X, L.P.
Date:01/27/2026
FHMLS X, L.P.
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS X, L.L.C., GP of FHMLS X, L.P.
Date:01/27/2026
FHMLS X, L.L.C.
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS X, L.L.C.
Date:01/27/2026
Frazier Life Sciences Public Fund, L.P.
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLSP, L.L.C., GP of FHMLSP, L.P., GP of Frazier Life Sciences Public Fund, L.P.
Date:01/27/2026
FHMLSP, L.P.
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLSP, L.L.C., GP of FHMLSP, L.P.
Date:01/27/2026
FHMLSP, L.L.C.
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLSP, L.L.C.
Date:01/27/2026
Frazier Life Sciences XI, L.P.
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS XI, L.L.C., GP of FHMLS XI, L.P., GP of Frazier Life Sciences XI, L.P.
Date:01/27/2026
FHMLS XI, L.P.
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS XI, L.L.C., GP of FHMLS XI, L.P.
Date:01/27/2026
FHMLS XI, L.L.C.
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS XI, L.L.C.
Date:01/27/2026
Frazier Life Sciences XII, L.P.
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS XII, L.L.C., GP of FHMLS XII, L.P., GP of Frazier Life Sciences XII, L.P.
Date:01/27/2026
FHMLS XII, L.P.
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS XII, L.L.C., GP of FHMLS XII, L.P.
Date:01/27/2026
FHMLS XII, L.L.C.
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS XII, L.L.C.
Date:01/27/2026
James N. Topper
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, Attorney-in-Fact for Patrick J. Heron, pursuant to Power of Attorney
Date:01/27/2026
Patrick J. Heron
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, Attorney-in-Fact for Patrick J. Heron, pursuant to Power of Attorney
Date:01/27/2026

FAQ

What does the latest MIRM Schedule 13D/A filing disclose about Frazier’s ownership?

The amendment shows multiple Frazier Life Sciences funds holding Mirum Pharmaceuticals common stock, including 3,566,912 shares by Frazier Life Sciences IX, L.P. (5.9% of the class) and 459,010 shares by Frazier Life Sciences X, L.P. (0.8%). Other affiliated funds report additional smaller positions.

How much of Mirum Pharmaceuticals (MIRM) is beneficially owned by James N. Topper and Patrick J. Heron?

James N. Topper is reported as beneficially owning 4,025,922 shares of Mirum common stock, or 6.7% of the class, through shared power over certain Frazier funds. Patrick J. Heron is reported as beneficially owning 4,108,404 shares, or 6.8%, including 76,779 shares issuable upon option exercise.

How were the ownership percentages in the MIRM Schedule 13D/A calculated?

The percentages are based on a total share count that combines 51,393,574 shares of Mirum common stock outstanding as of October 31, 2025 plus shares anticipated to be issued for the Bluejay Therapeutics acquisition and related private placements as described in Mirum’s Form 10-Q and Form 8-K filings.

What is the purpose of Frazier’s investment in Mirum Pharmaceuticals according to the filing?

The filing states that FLS IX, FLS X, FLSPF, FLS XI and FLS XII acquired their Mirum shares for investment purposes. They may buy or sell additional shares depending on market conditions and their evaluation of Mirum’s business, but they report no current plans for mergers, control changes, or other major corporate actions.

What registration rights do Frazier funds have for their MIRM shares and warrants?

Under a Registration Rights Agreement dated December 7, 2025, certain Frazier funds, including FLSPF, FLS X, FLS XI and FLS XII, are entitled to have Mirum register for resale their common shares and the common shares issuable upon exercise of pre-funded warrants purchased on January 23, 2026. Mirum agreed to bear the fees and expenses of this registration.

Does the Frazier Schedule 13D/A for MIRM indicate any plans to change Mirum’s control or strategy?

No. The Reporting Persons state they do not currently have plans for mergers, asset sales, board changes, capitalization changes, delisting, or other major corporate actions involving Mirum, beyond the possibility of buying or selling shares based on market and business evaluations.