Welcome to our dedicated page for Milestone Pharmaceuticals SEC filings (Ticker: MIST), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
Milestone Pharmaceuticals Inc. filings document a commercial-stage biopharmaceutical company focused on cardiovascular medicines, including CARDAMYST (etripamil) nasal spray for adults with PSVT. Its 8-K filings report financial results, commercial launch updates, regulatory and corporate updates, Regulation FD presentations and material events related to etripamil.
The filing record also covers Milestone's Nasdaq-listed common shares, proxy governance for annual shareholder meetings, board and voting matters, and capital-structure items such as the completed sale of a royalty interest tied to U.S. etripamil net product sales. These disclosures provide formal records of operating results, governance, financing arrangements and product-related corporate events.
Milestone Pharmaceuticals filed its annual report outlining a pivotal year in which the FDA approved CARDAMYST (etripamil) nasal spray for at-home treatment of PSVT and U.S. commercialization began in early 2026. The company is pursuing additional approvals, including an application filed with the EMA and an NDA accepted in China via partner Corxel.
Milestone is also advancing etripamil for atrial fibrillation with rapid ventricular rate, supported by positive Phase 2 ReVeRA data and an agreed Phase 3/sNDA path with the FDA. Despite this progress, the company remains loss-making, with a 2025 net loss of $63.1 million and an accumulated deficit of $430.6 million, and expects continued substantial operating losses while it invests in commercialization and late-stage development.
Milestone Pharmaceuticals President and CEO Joseph Oliveto filed an amended insider report updating the terms of a previously disclosed stock option grant. The filing shows an employee stock option to purchase 679,000 common shares at an exercise price of $1.96 per share.
The amendment states that the exercise price on the initial filings was incorrectly stated and is now corrected. One-fourth of the option shares will vest on February 2, 2027, with one thirty-sixth of the remaining shares vesting each month afterward, as long as Oliveto continues to provide service.
Milestone Pharmaceuticals Inc. reported an amended insider transaction for its Chief Medical Officer. The officer received an employee stock option to buy 204,000 common shares at an exercise price of $1.96 per share, granted on February 2, 2026 and expiring on February 2, 2036.
The amendment corrects an initially misstated exercise price. One-fourth of the option shares vest on February 2, 2027, with one thirty-sixth of the remaining shares vesting monthly thereafter, as long as the officer continues providing services.
Milestone Pharmaceuticals Inc. reported an amended insider transaction for its Chief Operating Officer. The filing corrects the exercise price on previously reported employee stock options and confirms a grant of 204,000 options with an exercise price of $1.96 per common share.
The options expire on February 2, 2036. One-fourth of the shares underlying the option vest on February 2, 2027, and the remaining shares vest in equal monthly installments over the following 36 months, as long as the executive continues providing service through each vesting date.
Milestone Pharmaceuticals Inc. reported an amended insider transaction for its Chief Commercial Officer. On February 2, 2026, the officer received an employee stock option to purchase 204,000 common shares at an exercise price of $1.96 per share, correcting an exercise price that had been stated incorrectly in initial filings.
According to the vesting schedule, one-fourth of the option shares vest on February 2, 2027, with one thirty-sixth of the remaining shares vesting monthly thereafter, as long as the officer continues providing service. Following this grant, the officer beneficially owns 204,000 stock options, held directly.
Milestone Pharmaceuticals Inc. insider filing: the company’s CFO and EVP of Corporate Development reported an amended employee stock option grant. The filing corrects the exercise price for an option to buy 204,000 common shares at $1.96 per share, granted on February 2, 2026 and expiring on February 2, 2036. One-fourth of the option vests on February 2, 2027, with the remaining shares vesting in equal monthly installments over the following 36 months while the executive continues providing service.
Milestone Pharmaceuticals granted its Chief Commercial Officer, Lorenz Muller, new equity awards. On February 2, 2026, he received an employee stock option for 204,000 common shares at an exercise price of $1.97 per share. One-fourth of these option shares vest on February 2, 2027, and the remaining shares vest in equal monthly installments over the following thirty-six months, as long as he continues providing service.
He was also granted 136,000 restricted stock units on the same date, each representing the right to receive one common share. These RSUs vest in four equal installments on February 2 of each year from 2027 through 2030, again contingent on continued service. After these grants, he beneficially owns all 204,000 option awards and 136,000 RSUs directly.
Milestone Pharmaceuticals Inc. granted new equity awards to its CFO and EVP of Corporate Development, Amit Hasija. On February 2, 2026, he received an employee stock option covering 204,000 common shares at an exercise price of $1.97 per share, expiring on February 2, 2036. One-fourth of these option shares vest on February 2, 2027, with the remaining shares vesting monthly over the following 36 months, contingent on continued service. He also received 136,000 restricted stock units, each representing one common share. These RSUs vest in four equal annual installments on February 2 of 2027, 2028, 2029, and 2030, also subject to continued service.
Milestone Pharmaceuticals Inc. reported that its Chief Operating Officer, Jeffrey Edward Nelson, received new equity awards. On February 2, 2026, he was granted an option to buy 204,000 common shares at $1.97 per share and 136,000 restricted stock units.
One-fourth of the option vests on February 2, 2027, with the remaining shares vesting monthly over three years, contingent on continued service. The RSUs vest in four equal annual installments on February 2 of 2027, 2028, 2029, and 2030, also subject to continued service.
Milestone Pharmaceuticals Inc. reported new equity awards to Chief Medical Officer David Bharucha. On February 2, 2026, he received an employee stock option covering 204,000 common shares at an exercise price of $1.97 per share, expiring February 2, 2036.
One-fourth of the option vests on February 2, 2027, with the remaining shares vesting in equal monthly installments over the following 36 months, assuming continued service. He also received 136,000 restricted stock units, each representing one common share, vesting in four equal annual installments on February 2 of 2027, 2028, 2029 and 2030, subject to continued service.