STOCK TITAN

Neurocrine (NBIX) HR chief sells 36,937 shares and exercises options in pre-set plan

Filing Impact
(Very High)
Filing Sentiment
(Very Negative)
Form Type
4

Rhea-AI Filing Summary

Neurocrine Biosciences’ Chief Human Resources Officer Julie Cooke reported a mix of option exercise and share sales in company common stock. On June 2, 2026, she exercised 24,965 non-qualified stock options at an exercise price of $81.49 per share, converting them into common shares. The filing shows her holding 59,311 common shares directly after this exercise.

That same day, she executed a series of open-market sales totaling 36,937 common shares at weighted average prices ranging from the mid‑$154 to high‑$158 area, with specific ranges from $154.20 to $158.91. A footnote states these dispositions were carried out by a broker under a pre‑arranged Rule 10b5‑1 trading plan adopted on March 3, 2026. The filing also notes that 20,334 of the reported shares are held by the Cooke Family Trust of 2004, over which Cooke has voting and investment power.

Positive

  • None.

Negative

  • None.
Insider Cooke Julie
Role Chief Human Resources Officer
Sold 36,937 shs ($5.77M)
Type Security Shares Price Value
Exercise Non-Qualified Stock Option 24,965 $0.00 --
Exercise Common Stock 24,965 $81.49 $2.03M
Sale Common Stock 14,214 $154.8252 $2.20M
Sale Common Stock 5,466 $155.4566 $850K
Sale Common Stock 4,216 $156.766 $661K
Sale Common Stock 9,521 $157.6161 $1.50M
Sale Common Stock 3,520 $158.5897 $558K
Holdings After Transaction: Non-Qualified Stock Option — 0 shares (Direct, null); Common Stock — 59,311 shares (Direct, null)
Footnotes (1)
  1. Includes an aggregate of 176 shares purchased on February 27, 2026 from the Neurocrine Biosciences, Inc. 2018 Employee Stock Purchase Plan. The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person on March 3, 2026. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan. Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $154.20 to $155.19. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $155.20 to $156.19. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $156.26 to $157.25. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $157.26 to $158.25. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $158.26 to $158.91. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. 20,334 of the reported shares are held by the Cooke Family Trust of 2004 U/A 12/28/2004, of which the Reporting Person has voting and investment power. The option was granted February 5, 2018 and vested in 48 equal monthly installments beginning March 5, 2018.
Shares sold 36,937 shares Total common shares sold on June 2, 2026 in open-market trades
Options exercised 24,965 shares Non-qualified stock options converted to common stock on June 2, 2026
Option exercise price $81.49/share Exercise price for non-qualified stock options granted February 5, 2018
Post-exercise holdings 59,311 shares Common shares held directly after option exercise transaction
Sale price range $154.20–$158.91 Weighted average sale price ranges for common stock sales
Trust-held shares 20,334 shares Shares held by the Cooke Family Trust of 2004 with voting and investment power
Rule 10b5-1 trading plan regulatory
"disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan"
A Rule 10b5-1 trading plan is a pre-arranged schedule that allows company insiders to buy or sell stock at specific times, even if they have inside information. It helps prevent accusations of unfair trading by making these transactions look planned and transparent, rather than sneaky or illegal.
Non-Qualified Stock Option financial
"security_title": "Non-Qualified Stock Option""
A non-qualified stock option (NSO) is a contract that lets an employee or service provider buy company shares at a fixed price for a set period, like a voucher to purchase stock later at today’s price. It matters to investors because exercising NSOs creates ordinary income for the holder and can increase share count, affecting a company’s earnings and ownership mix; think of it as a future sale that can dilute existing shareholders and has immediate tax consequences for the recipient.
weighted average sales price financial
"Represents a weighted average sales price per share. These shares were sold in multiple transactions"
Employee Stock Purchase Plan financial
"shares purchased on February 27, 2026 from the Neurocrine Biosciences, Inc. 2018 Employee Stock Purchase Plan"
An employee stock purchase plan is a company program that lets workers buy shares through small payroll deductions, often at a discount to the market price and after a set offering period. Think of it like a workplace savings plan that turns into ownership: it encourages employees to share in the company’s success and can create predictable buying or selling of stock that investors watch because it affects supply, demand and employee incentives.
vesting financial
"The option was granted February 5, 2018 and vested in 48 equal monthly installments"
Vesting is the process by which you earn full ownership of something, like company stock or a retirement benefit, over time. It’s like earning the right to keep a gift piece by piece the longer you stay with a company, making sure employees stay committed before they receive all the benefits.
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SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Cooke Julie

(Last)(First)(Middle)
6027 EDGEWOOD BEND CT.

(Street)
SAN DIEGO CALIFORNIA 92130

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
NEUROCRINE BIOSCIENCES INC [ NBIX ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director10% Owner
XOfficer (give title below)Other (specify below)
Chief Human Resources Officer
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
06/02/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock06/02/2026M24,965A$81.4959,311(1)D
Common Stock06/02/2026S(2)14,214D$154.8252(3)45,097D
Common Stock06/02/2026S(2)5,466D$155.4566(4)39,631D
Common Stock06/02/2026S(2)4,216D$156.766(5)35,415D
Common Stock06/02/2026S(2)9,521D$157.6161(6)25,894D
Common Stock06/02/2026S(2)3,520D$158.5897(7)22,374(8)D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Non-Qualified Stock Option$81.4906/02/2026M24,965 (9)02/05/2028Common Stock24,965$00D
Explanation of Responses:
1. Includes an aggregate of 176 shares purchased on February 27, 2026 from the Neurocrine Biosciences, Inc. 2018 Employee Stock Purchase Plan.
2. The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person on March 3, 2026. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.
3. Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $154.20 to $155.19. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.
4. Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $155.20 to $156.19. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.
5. Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $156.26 to $157.25. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.
6. Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $157.26 to $158.25. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.
7. Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $158.26 to $158.91. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.
8. 20,334 of the reported shares are held by the Cooke Family Trust of 2004 U/A 12/28/2004, of which the Reporting Person has voting and investment power.
9. The option was granted February 5, 2018 and vested in 48 equal monthly installments beginning March 5, 2018.
Remarks:
/s/ Darin Lippoldt, Attorney-in-Fact06/04/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What insider transactions did NBIX executive Julie Cooke report on this Form 4?

Julie Cooke reported exercising non-qualified stock options and selling common shares. She exercised 24,965 options at $81.49 per share and sold 36,937 Neurocrine Biosciences common shares in open-market transactions on June 2, 2026, at weighted average prices in the mid-$150s.

How many Neurocrine Biosciences (NBIX) shares did Julie Cooke sell?

She sold a total of 36,937 common shares. These were completed in multiple open-market transactions on June 2, 2026, at weighted average prices ranging from $154.20 to $158.91 per share, as detailed in several footnotes in the Form 4 filing.

At what price did Julie Cooke exercise her NBIX stock options?

She exercised 24,965 non-qualified stock options at an exercise price of $81.49 per share. These options, granted on February 5, 2018, had vested in 48 equal monthly installments beginning March 5, 2018, according to the disclosed vesting schedule.

Were Julie Cooke’s NBIX share sales under a Rule 10b5-1 trading plan?

Yes. A footnote states the dispositions were executed by a broker under a Rule 10b5-1 trading plan. The plan was adopted by Julie Cooke on March 3, 2026, and company policy restricts her from amending or modifying any such plan after adoption.

What NBIX share price ranges were involved in Julie Cooke’s sales?

The reported sales were executed at weighted average prices within specified ranges. Footnotes state the transactions occurred between $154.20 and $158.91 per share, broken into several $1-wide price bands, with details available from the issuer upon request.