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Revenue growth and smaller losses at NeoGenomics (NASDAQ: NEO)

Filing Impact
(High)
Filing Sentiment
(Neutral)
Form Type
8-K

Rhea-AI Filing Summary

NeoGenomics, Inc. reported fourth-quarter and full-year 2025 results showing solid revenue growth but continued net losses. Fourth-quarter revenue rose 11% to $190.2 million, with full-year revenue up 10% to $727.3 million, driven by higher test volumes and a shift toward higher value oncology diagnostics.

Fourth-quarter net loss improved to $9.9 million from $15.3 million, while full-year net loss widened to $108.0 million due to items such as impairment and litigation costs. Non-GAAP adjusted EBITDA was positive $13.4 million in Q4 and $43.4 million for 2025, both modestly higher than 2024.

The company highlighted strong growth in next‑generation sequencing, progress on its RaDaR ST minimal residual disease assay, and a successful resolution of RaDaR ST patent litigation. For 2026, NeoGenomics guides revenue to $793–801 million, a smaller GAAP net loss of $50–63 million, and adjusted EBITDA of $55–57 million.

Positive

  • None.

Negative

  • None.

Insights

NeoGenomics is growing revenue double digits while gradually improving profitability and guiding to smaller 2026 losses.

NeoGenomics delivered 2025 revenue of $727.3M, up 10%, with Q4 revenue of $190.2M, up 11%. Growth is supported by higher clinical volumes, richer test mix, and contribution from the Pathline acquisition, while next‑generation sequencing outpaced the broader market according to management commentary.

Profitability remains a key issue. GAAP net loss increased to $108.0M in 2025 from $78.7M, reflecting items such as impairment and IP litigation costs, even as Q4 net loss narrowed to $9.9M. Non‑GAAP adjusted EBITDA improved modestly to $43.4M, helped by cost controls and mix shift.

2026 guidance implies continued top-line growth and better earnings quality: revenue of $793–801M (up 9–10%), GAAP net loss reduced to $50–63M, and adjusted EBITDA rising to $55–57M. Execution on the RaDaR ST MRD launch and ongoing test mix improvement will be important drivers within the 2026 period.

0001077183FALSE00010771832026-02-172026-02-17

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, DC 20549 
 
FORM 8-K  
CURRENT REPORT
Pursuant to Section 13 or 15(d)
of the Securities Exchange Act of 1934
Date of Report (Date of earliest event reported)
February 17, 2026
 
NEOGENOMICS, INC.
(Exact name of registrant as specified in its charter) 
 
Nevada
001-35756
74-2897368
(State or other jurisdiction
of incorporation)
(Commission
File Number)
(I.R.S. Employer
Identification No.)

 
9490 NeoGenomics Way,Fort Myers,Florida33912
(Address of principal executive offices)(Zip Code)
(239) 768-0600
(Registrant’s telephone number, including area code) 
 
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
 
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:Trading Symbol(s):Name of each exchange on which registered:
Common Stock, par value $0.001 per shareNEOThe Nasdaq Stock Market LLC
Indicate by check mark whether the registrant is an emerging growth company as defined in as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).
Emerging growth company
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐ 



Item 2.02
Results of Operations and Financial Condition.
On February 17, 2026, NeoGenomics, Inc. issued a press release reporting its results for its fourth fiscal quarter of 2025 and full year ended December 31, 2025. The press release is furnished herewith as Exhibit 99.1 and is incorporated herein by reference.
This information shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that section, and it shall not be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such filing.
 
Item 9.01
Financial Statements and Exhibits.

(a)Not applicable
(b)Not applicable
(c)Not applicable
(d)Exhibits.
99.1
Press Release of NeoGenomics, Inc. dated February 17, 2026.
104 Cover Page Interactive Data File (embedded within the Inline XBRL document).

SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
 
NEOGENOMICS, INC.
Date:February 17, 2026
By:
/s/ Jeffrey S. Sherman
Jeffrey S. Sherman
Chief Financial Officer



Exhibit 99.1
image1a.jpg
NeoGenomics Reports Fourth Quarter and
Full Year 2025 Results
Full year revenue increased 10% to $727 million;
Full year clinical revenue grew 15%, or 13% excluding the Pathline acquisition;
Successfully resolved RaDaR ST patent litigation

Fort Myers, Florida, (February 17, 2026) - NeoGenomics, Inc. (Nasdaq: NEO) (the “Company”), a leading provider of oncology diagnostic solutions that enable precision medicine, today announced its fourth-quarter and full year results for the period ended December 31, 2025.

Fourth Quarter and Full Year 2025 Highlights
Fourth quarter consolidated revenue increased 11% to $190 million; Full year consolidated revenue increased 10% to $727 million
Fourth quarter net loss decreased 36% to $10 million; Full year net loss increased 37% to $108 million
Fourth quarter adjusted EBITDA(1) increased 13% to positive $13 million; Full year adjusted EBITDA increased 9% to positive $43 million
“We ended 2025 on a strong note, delivering double-digit revenue growth in the fourth quarter on the strength of our clinical volumes and ongoing mix shift toward higher value tests,” stated Tony Zook, CEO of NeoGenomics. “Notably, NGS grew 23% in Q4 and 22% for the full year, both well ahead of the market growth rate, reflecting our ability to successfully pull innovation through the community channel, where we enjoy a leadership position and where approximately 80% of all cancer care is delivered today.”
“Looking ahead, the imminent clinical launch of our RaDaR ST MRD assay further enhances our menu of advanced tests and allows us to address the $20+ billion molecular residual disease monitoring market. And while we anticipate modest revenue contribution from MRD in 2026, we believe the longer-term opportunity, in 2027 and beyond, is substantial. We believe RaDaR ST, together with our PanTracer family of therapy selection solutions, will be a key driver of our revenue growth over the long term. We envision a world where every cancer treatment decision is as personal as the patient, and this drives what we do every day. I am pleased with our progress in 2025 and excited about our current momentum.”
Fourth Quarter Results
Consolidated revenue for the fourth quarter of 2025 was $190 million, an increase of 11% over the same period in 2024. Average revenue per clinical test (“revenue per test”) increased by 5% to $488 with 7% growth excluding recently acquired Pathline tests. This increase reflects a shift towards higher value tests, including NGS, and the positive impact of strategic reimbursement initiatives.
Consolidated gross profit for the fourth quarter of 2025 was $83 million, an increase of 8% compared to the fourth quarter of 2024. This increase was primarily due to an increase in revenue partially offset by higher compensation and benefit costs, and an increase in supplies costs. Consolidated gross profit margin(1), including amortization of acquired intangible assets and stock-based compensation expense, was 43.8%. Adjusted Gross Profit Margin(1), excluding amortization of acquired intangible assets and stock-based compensation expense, was 46.4%.
Operating expenses for the fourth quarter of 2025 remained relatively flat at $97 million compared to the fourth quarter of 2024. Operating expenses included higher compensation and benefit costs offset by a decrease in restructuring charges due to the completion of the restructuring program in 2024.
NeoGenomics, Inc. | 9490 NeoGenomics Way Fort Myers, FL 33912

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Net loss for the quarter was $10 million compared to net loss of $15 million for the fourth quarter of 2024.
Adjusted EBITDA(1) was positive $13 million compared to positive $12 million in the fourth quarter of 2024. Adjusted Net Income(1) was $8 million compared to Adjusted Net Income(1) of $6 million in the fourth quarter of 2024.
Cash and cash equivalents totaled $160 million at quarter end.
Full Year Results
Consolidated revenue for 2025 was $727 million, an increase of 10% over 2024. This increase primarily reflects an increase in test volumes, a shift towards higher value tests, and the positive impact of strategic reimbursement initiatives. Revenues from the Pathline acquisition also contributed to revenue growth, which was partially offset by lower non-clinical revenue due to macro trends in the pharmaceutical and biotech industries, and a less favorable test mix. Net loss for 2025 was $108 million compared to net loss of $79 million in 2024. Adjusted EBITDA(1) for 2025 was positive $43 million compared to positive $40 million in 2024. Adjusted net income(1) for 2025 was $15 million compared to adjusted net income(1) of $14 million in 2024.
(1) The Company has provided adjusted financial information that has not been prepared in accordance with GAAP, including Adjusted EBITDA, Adjusted Gross Profit Margin, Adjusted Net (Loss) Income, and Adjusted Diluted EPS. Each of these measures is defined in the section of this report entitled “Use of Non-GAAP Financial Measures.” See also the tables reconciling such measures to their closest GAAP equivalent.
2026 Financial Guidance
The Company issued its full-year 2026 guidance(2) (in millions):
FY 2025FY 2026 GuidanceYOY % Change from FY 2025
ActualLowHighLowHigh
Consolidated revenue$727$793$8019%10%
Net loss$(108)$(63)$(50)42%54%
Adjusted EBITDA$43$55$5727%31%
(2) The Company reserves the right to adjust this guidance at any time based on the ongoing execution of its business plan. Current and prospective investors are encouraged to perform their own due diligence before buying or selling any of the Company’s securities, and are reminded that the foregoing estimates should not be construed as a guarantee of future performance.
Conference Call
The Company has scheduled a webcast and conference call to discuss its fourth quarter and full year 2025 results on Tuesday, February 17, 2026 at 8:30 a.m. Eastern Time. To access the live call via telephone, interested investors should dial (888) 506-0062 (domestic) or (973) 528-0011 (international) at least five minutes prior to the call. The participant access code provided for this call is 825997. The live webcast may be accessed by visiting the Investor Relations section of our website at ir.neogenomics.com. A replay of the webcast will be available shortly after the conclusion of the call and will be archived on the Company’s website.
About NeoGenomics, Inc.
NeoGenomics, Inc. is a premier cancer diagnostics company specializing in cancer genetics testing and information services. We offer one of the most comprehensive oncology-focused testing menus across the cancer continuum, serving oncologists, pathologists, hospital systems, academic centers, and pharmaceutical firms with innovative diagnostic and predictive testing to help them diagnose and treat cancer. Headquartered in Fort Myers, FL, NeoGenomics operates a network of CAP-accredited and CLIA-certified laboratories for full-service sample processing and analysis services throughout the US and a CAP-accredited full-service sample-processing laboratory in Cambridge, United Kingdom.
We routinely post information that may be important to investors on our website at https://www.neogenomics.com.


NeoGenomics, Inc. | 9490 NeoGenomics Way Fort Myers, FL 33912

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Forward Looking Statements
This press release includes forward-looking statements. These forward-looking statements generally can be identified by the use of words such as “anticipate,” “expect,” “plan,” “could,” “would,” “may,” “will,” “believe,” “estimate,” “forecast,” “goal,” “project,” “guidance,” “plan,” “potential” and other words of similar meaning, although not all forward-looking statements include these words. These forward-looking statements include statements regarding the Company’s strategy, future operations, future financial position, future revenues, projected costs and capital expenditures, prospects and plans, estimates of market size and position, and objectives of Management. Each forward-looking statement contained in this press release is subject to a number of risks and uncertainties that could cause actual results to differ materially from those expressed or implied by such statement. Applicable risks and uncertainties include, among others, the Company's ability to identify and implement appropriate financial and operational initiatives to improve performance, to identify and recruit executive candidates, to continue gaining new customers, offer new types of tests, integrate its acquisitions and otherwise implement its business plan, and the risks identified under the heading "Risk Factors" contained in the Company's Annual Report on Form 10-K, Quarterly Reports on Form 10-Q and the Company's other filings with the Securities and Exchange Commission.
We caution investors not to place undue reliance on the forward-looking statements contained in this press release. You are encouraged to read our filings with the SEC, available at www.sec.gov, for a discussion of these and other risks and uncertainties. The forward-looking statements in this press release speak only as of the date of this document (unless another date is indicated), and we undertake no obligation to update or revise any of these statements. Our business is subject to substantial risks and uncertainties, including those referenced above. Investors, potential investors, and others should give careful consideration to these risks and uncertainties.

Investor Contact
Kendra Sweeney
kendra.sweeney@neogenomics.com

Media Contact
Andrea Sampson
asampson@sampsonprgroup.com


NeoGenomics, Inc. | 9490 NeoGenomics Way Fort Myers, FL 33912

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NeoGenomics, Inc.
CONDENSED CONSOLIDATED BALANCE SHEETS
(Unaudited, in thousands)
As of December 31,
20252024
ASSETS
Current Assets
     Cash and cash equivalents$159,618 $367,012 
     Marketable securities, at fair value— 19,832 
     Accounts receivable, net159,242 150,540 
     Inventories28,566 26,748 
     Prepaid assets21,443 20,165 
     Other current assets7,417 11,722 
     Total current assets
376,286 596,019 
Property and equipment (net of accumulated depreciation of $209,057 and $189,990, respectively)
84,834 94,103 
Operating lease right-of-use assets78,444 79,583 
Intangible assets, net286,528 339,681 
Goodwill524,344 522,766 
Other assets9,394 5,886 
Total non-current assets983,544 1,042,019 
Total assets$1,359,830 $1,638,038 
LIABILITIES AND STOCKHOLDERS’ EQUITY
Current liabilities
     Accounts payable and other current liabilities$83,524 $97,083 
     Current portion of operating lease liabilities4,776 3,381 
Current portion of convertible senior notes, net— 200,777 
     Total current liabilities88,300 301,241 
Long-term liabilities
Operating lease liabilities62,822 60,841 
     Convertible senior notes, net341,858 340,335 
     Deferred income tax liabilities, net18,219 21,510 
     Other long-term liabilities12,069 11,772 
     Total long-term liabilities
434,968 434,458 
        Total liabilities
523,268 735,699 
Stockholders’ equity
          Total stockholders’ equity836,562 902,339 
               Total liabilities and stockholders’ equity$1,359,830 $1,638,038 
NeoGenomics, Inc. | 9490 NeoGenomics Way Fort Myers, FL 33912

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NeoGenomics, Inc.
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
(Unaudited, in thousands, except per share amounts)
 
Three Months Ended December 31,Years Ended December 31,
2025202420252024
NET REVENUE$190,170 $172,000 $727,332 $660,566 
COST OF REVENUE106,827 94,743 413,039 370,466 
GROSS MARGIN83,343 77,257 314,293 290,100 
Operating expenses:
General and administrative63,509 63,643 273,337 259,737 
Research and development9,179 7,969 37,077 31,159 
Sales and marketing23,443 22,339 92,007 84,652 
Restructuring charges— 1,707 — 6,658 
Impairment charges626 — 27,753 — 
Total operating expenses96,757 95,658 430,174 382,206 
LOSS FROM OPERATIONS(13,414)(18,401)(115,881)(92,106)
Interest income(1,523)(4,328)(9,070)(18,427)
Interest expense599 1,624 3,753 6,617 
Other (income) expense, net(84)431 (296)379 
Loss before taxes(12,406)(16,128)(110,268)(80,675)
Income tax benefit(2,525)(804)(2,243)(1,949)
NET LOSS$(9,881)$(15,324)$(108,025)$(78,726)
NET LOSS PER SHARE
Basic$(0.08)$(0.12)$(0.84)$(0.62)
Diluted$(0.08)$(0.12)$(0.84)$(0.62)
WEIGHTED AVERAGE COMMON SHARES OUTSTANDING
Basic128,648 127,160 128,101 126,658 
Diluted128,648 127,160 128,101 126,658 
NeoGenomics, Inc. | 9490 NeoGenomics Way Fort Myers, FL 33912

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NeoGenomics, Inc.
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
(Unaudited, in thousands)
Years Ended December 31,
20252024
CASH FLOWS FROM OPERATING ACTIVITIES
Net loss$(108,025)$(78,726)
Adjustments to reconcile net loss to net cash provided by operating activities:
Depreciation36,072 39,101 
Amortization of intangibles31,752 33,446 
Stock-based compensation41,316 33,413 
Non-cash operating lease expense6,752 8,926 
Amortization of convertible debt discount1,910 2,725 
Amortization of debt issuance costs87 189 
Loss (gain) on disposal of assets, net31 (49)
Impairment charges27,753 — 
Impairment of long-lived assets— 450 
Other adjustments(323)178 
Changes in assets and liabilities, net:(32,095)(32,630)
Net cash provided by operating activities$5,230 $7,023 
CASH FLOWS FROM INVESTING ACTIVITIES
Proceeds from maturities of marketable securities20,060 53,916 
Purchases of property and equipment(27,008)(41,061)
Proceeds from assets held for sale, net of closing costs2,066 — 
Business acquisitions, net of cash acquired(6,454)— 
Purchase of convertible note(500)— 
Purchase of equity securities(500)— 
Net cash (used in) provided by investing activities$(12,336)$12,855 
CASH FLOWS FROM FINANCING ACTIVITIES
Issuance of common stock, net962 4,646 
Repayment of convertible debt(201,250)— 
Net cash (used in) provided by financing activities$(200,288)$4,646 
Net change in cash and cash equivalents$(207,394)$24,524 
Cash and cash equivalents, beginning of year$367,012 $342,488 
Cash, cash equivalents and restricted cash, end of year$159,618 $367,012 


NeoGenomics, Inc. | 9490 NeoGenomics Way Fort Myers, FL 33912

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Use of Non-GAAP Financial Measures
The Company reports its financial results in accordance with generally accepted accounting principles in the United States (“GAAP”). However, in order to provide greater transparency regarding our operating performance, the financial results and financial guidance in this press release refer to certain non-GAAP financial measures that involve adjustments to GAAP results. Non-GAAP financial measures exclude certain income and/or expense items that management believes are not directly attributable to the Company’s core operating results and/or certain items that are inconsistent in amounts and frequency, making it difficult to perform a meaningful evaluation of our current or past operating performance. Management believes that the presentation of operating results using non-GAAP financial measures provides useful supplemental information to investors by facilitating the analysis of the Company’s core test-level operating results across reporting periods. These non-GAAP financial measures may also assist investors in evaluating future prospects. Management also uses non-GAAP financial measures for financial and operational decision making, planning and forecasting purposes and to manage the business. These non-GAAP financial measures do not replace the presentation of financial information in accordance with U.S. GAAP financial results and may exclude items that are significant to understanding and assessing the Company's financial results. Therefore, should not be considered measures of liquidity or considered in isolation or as an alternative to other measures of the Company's profitability or performance under GAAP. The Company's presentation of non-GAAP financial measures is unlikely to be comparable to similarly-titled non-GAAP financial measures provided by other companies.
Definitions of Non-GAAP Financial Measures
Non-GAAP Adjusted EBITDA
“Adjusted EBITDA” is defined by NeoGenomics as net (loss) income from continuing operations before: (i) interest income, (ii) interest expense, (iii) tax (benefit) or expense, (iv) depreciation and amortization expense, (v) stock-based compensation expense, and, if applicable in a reporting period, (vi) CEO transition costs, (vii) acquisition and integration related expenses, (viii) restructuring charges, (ix) impairment charges, (x) intellectual property (“IP”) litigation costs, and (xi) other significant or non-operating (income) or expenses, net.
Non-GAAP Adjusted Cost of Revenue, Adjusted Gross Profit and Adjusted Gross Profit Margin
“Adjusted cost of revenue” is defined by NeoGenomics as cost of revenue before: (i) amortization of acquired intangible assets, and (ii) stock-based compensation expense.
“Adjusted gross profit” is defined by NeoGenomics as total revenue less adjusted cost of revenue.
“Adjusted gross profit margin” is defined by NeoGenomics as adjusted cost of revenue divided by total revenue.
Non-GAAP Adjusted Net (Loss) Income
“Adjusted net (loss) income” is defined by NeoGenomics as net (loss) income from continuing operations plus: (i) amortization of intangible assets, (ii) stock-based compensation expense, and, if applicable in a reporting period, (iii) CEO transition costs, (iv) acquisition and integration related expenses, (v) restructuring charges, (vi) impairment charges, (vii) IP litigation costs, and (viii) other significant or non-operating (income) or expenses, net. If GAAP net (loss) income is negative and adjusted net (loss) income is positive, adjusted net (loss) income will also be adjusted to reverse any recognized interest expense (including any amortization of discounts) on the convertible notes using the if-converted method unless the effect of this adjustment on both the adjusted net (loss) income and weighted average diluted common shares outstanding would be anti-dilutive. If GAAP net (loss) income is positive and adjusted net (loss) income is negative, adjusted net (loss) income will also be adjusted to reverse any recognized interest expense (including any amortization of discounts) on the convertible notes using the if-converted method.
Non-GAAP Adjusted Diluted EPS
“Adjusted diluted EPS” is defined by NeoGenomics as adjusted net (loss) income divided by adjusted diluted shares outstanding. If GAAP net (loss) income is negative and adjusted net (loss) income is positive, adjusted diluted shares outstanding will also include any options or restricted stock that would be outstanding as dilutive instruments using the treasury stock method and the weighted average number of common shares that would be outstanding if the convertible notes were converted into common stock on the original issue date based on the number of days such common shares would have been outstanding in the reporting period, until the effect of these adjustments are anti-dilutive. If GAAP net (loss) income is positive and adjusted net (loss) income is negative, adjusted diluted shares outstanding will exclude any options or restricted stock that would be outstanding as dilutive instruments using the treasury stock method and the weighted average number of common shares that would be outstanding if the convertible notes were converted into common stock on the original issue date based on the number of days such common shares would have been outstanding in the reporting period.
The following tables present reconciliations of the Company’s non-GAAP financial measures to the most directly comparable financial measures calculated in accordance with GAAP.
NeoGenomics, Inc. | 9490 NeoGenomics Way Fort Myers, FL 33912

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Reconciliation of GAAP Net Loss to Non-GAAP EBITDA and Adjusted EBITDA
(Unaudited, in thousands)

Three Months Ended December 31,Years Ended December 31,
2025202420252024
NET LOSS$(9,881)$(15,324)$(108,025)$(78,726)
Adjustments to net loss
Interest income(1,523)(4,328)(9,070)(18,427)
Interest expense599 1,624 3,753 6,617 
Income tax benefit(2,525)(804)(2,243)(1,949)
Depreciation8,763 9,827 36,072 39,101 
Amortization of intangibles7,632 8,361 31,752 33,446 
EBITDA (non-GAAP)3,065 (644)(47,761)(19,938)
Further adjustments to EBITDA:
CEO transition costs(1)
351 330 3,500 330 
Acquisition and integration related expenses(2)
1,090 — 7,266 — 
Stock-based compensation8,042 8,328 41,316 33,413 
Restructuring charges— 1,707 — 6,658 
Impairment charges(3)
626 — 27,753 — 
IP litigation costs(4)
206 1,397 11,283 13,753 
Other significant expenses, net(5)
— 755 — 5,392 
Adjusted EBITDA (non-GAAP)$13,380 $11,873 $43,357 $39,608 
_________________
(1) For the three months ended December 31, 2025, CEO transition costs include executive retention costs. For the year ended December 31, 2025, CEO transition costs include severance costs, executive retention costs, and executive search costs. For the three months and year ended December 31, 2024, CEO transition costs include executive search costs.
(2) For the three months and year ended December 31, 2025, acquisition and integration related expenses include consulting and legal fees, severance costs, and employee retention costs. There were no such costs for the three months and year ended December 31, 2024.
(3) For the three months ended December 31, 2025, impairment charges include a loss on the sale of Trapelo Health, LLC assets. For the year ended December 31, 2025, impairment charges include losses from InVisionFirst®-Lung intangible asset impairment and inventory write-off, and an impairment loss on the sale of Trapelo Health, LLC assets. There were no such costs for the three months and year ended December 31, 2024.
(4) For the three months ended December 31, 2025, IP litigation costs include legal fees. For the year ended December 31, 2025, IP litigation costs include a legal fees and a settlement payment. For the three months ended December 31, 2024, IP litigation costs include legal fees. For the year ended December 31, 2024, IP litigation costs include legal fees and a settlement payment.
(5) For the three months ended December 31, 2024, other significant (income) expenses, net, includes site closure costs. For the year ended December 31, 2024, other significant (income) expenses, net, includes site closure costs, severance costs, and fees related to non-recurring legal matters. There were no such costs for the three months and year ended December 31, 2025.


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Reconciliation of Consolidated GAAP Cost of Revenue, Gross Profit and Gross Profit Margin to
Non-GAAP Adjusted Cost of Revenue, Adjusted Gross Profit and Adjusted Gross Profit Margin
(Unaudited, dollars in thousands)
Three Months Ended December 31,Years Ended December 31,
20252024% Change20252024% Change
Consolidated:
Total revenue (GAAP)$190,170$172,00010.6 %$727,332$660,56610.1 %
Cost of revenue (GAAP)$106,827$94,74312.8 %$413,039$370,46611.5 %
Adjustments to cost of revenue(1)
(4,964)(5,292)(20,353)(21,127)
Adjusted cost of revenue (non-GAAP)$101,863$89,45113.9 %$392,686$349,33912.4 %
Gross profit (GAAP)$83,343$77,2577.9 %$314,293$290,1008.3 %
Adjusted gross profit (non-GAAP)$88,307$82,5497.0 %$334,646$311,2277.5 %
Gross profit margin (GAAP)43.8 %44.9 %43.2 %43.9 %
Adjusted gross profit margin (non-GAAP)46.4 %48.0 %46.0 %47.1 %
_________________
(1) Cost of revenue adjustments for the three months ended December 31, 2025 includes $4.6 million of amortization of acquired intangible assets and $0.3 million of stock-based compensation. Cost of revenue adjustments for the three months ended December 31, 2024 includes $4.9 million of amortization of acquired intangible assets and $0.4 million of stock-based compensation. Cost of revenue adjustments for the year ended December 31, 2025 includes $18.9 million of amortization of acquired intangible assets and $1.4 million of stock-based compensation. Cost of revenue adjustments for the year ended December 31, 2024 includes $19.6 million of amortization of acquired intangible assets and $1.4 million of stock-based compensation.



NeoGenomics, Inc. | 9490 NeoGenomics Way Fort Myers, FL 33912

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Reconciliation of GAAP Net Loss to Non- GAAP Adjusted Net Loss and
GAAP EPS to Non-GAAP Adjusted EPS
(Unaudited, in thousands, except per share amounts)

Three Months Ended December 31,Years Ended December 31,
2025202420252024
Net loss (GAAP)$(9,881)$(15,324)$(108,025)$(78,726)
Adjustments to net loss:
Amortization of intangibles7,632 8,361 31,752 33,446 
CEO transition costs(1)
351 330 3,500 330 
Acquisition and integration related expenses(2)
1,090 — 7,266 — 
Stock-based compensation expense8,042 8,328 41,316 33,413 
Restructuring charges— 1,707 — 6,658 
Impairment charges(3)
626 — 27,753 — 
IP litigation costs(4)
206 1,397 11,283 13,753 
Other significant expenses, net(5)
— 755 — 5,392 
Adjusted net income (non-GAAP)$8,066 $5,554 $14,845 $14,266 
Net loss per diluted share (GAAP)
Diluted EPS$(0.08)$(0.12)$(0.84)$(0.62)
Adjustments to net loss per diluted share:
Amortization of intangibles0.06 0.07 0.25 0.26 
CEO transition costs(1)
— — 0.03 — 
Acquisition and integration related expenses(2)
0.01 — 0.06 — 
Stock-based compensation expense0.06 0.07 0.32 0.26 
Restructuring charges— 0.01 — 0.05 
Impairment charges(3)
— — 0.22 — 
IP litigation costs(4)
— 0.01 0.09 0.11 
Other significant expenses, net(5)
— 0.01 — 0.05 
Rounding and impact of diluted shares in adjusted diluted share(6)
0.01 (0.01)(0.01)— 
Adjusted diluted EPS (non-GAAP)$0.06 $0.04 $0.12 $0.11 
Weighted average shares used in computation of
adjusted diluted EPS:
Diluted common shares (GAAP)128,648 127,160 128,101 126,658 
Dilutive effect of options, restricted stock, and converted shares(7)(8)
— — — — 
Adjusted diluted shares outstanding (non-GAAP)128,648 127,160 128,101 126,658 
_________________
(1) For the three months ended December 31, 2025, CEO transition costs include executive retention costs. For the year ended December 31, 2025, CEO transition costs include severance costs, executive retention costs, and executive search costs. For the three months and year ended December 31, 2024, CEO transition costs include executive search costs.
(2) For the three months and year ended December 31, 2025, acquisition and integration related expenses include consulting and legal fees, severance costs, and employee retention costs. There were no such costs for the three months and year ended December 31, 2024.
(3) For the three months ended December 31, 2025, impairment charges include a loss on the sale of Trapelo Health, LLC assets. For the year ended December 31, 2025, impairment charges include losses from InVisionFirst®-Lung intangible asset impairment and inventory write-off, and an impairment loss on the sale of Trapelo Health, LLC assets. There were no such costs for the three months and year ended December 31, 2024.
(4) For the three months ended December 31, 2025, IP litigation costs include legal fees. For the year ended December 31, 2025, IP litigation costs include a legal fees and a settlement payment. For the three months ended December 31, 2024, IP litigation costs include legal fees. For the year ended December 31, 2024, IP litigation costs include legal fees and a settlement payment.
(5) For the three months ended December 31, 2024, other significant (income) expenses, net, includes site closure costs. For the year ended
NeoGenomics, Inc. | 9490 NeoGenomics Way Fort Myers, FL 33912

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December 31, 2024, other significant (income) expenses, net, includes site closure costs, severance costs, and fees related to non-recurring legal matters. There were no such costs for the three months and year ended December 31, 2025.
(6) This adjustment is for rounding and, in those periods in which GAAP net (loss) income is negative and adjusted net (loss) income is positive or GAAP net (loss) income is positive and adjusted net (loss) income is negative, also compensates for the effects of additional diluted shares included or excluded in adjusted diluted shares outstanding for the treasury stock impact of outstanding stock options and restricted stock and the if-converted impact of convertible notes.
(7) In those periods in which GAAP net (loss) income is negative and adjusted net (loss) income is positive, this adjustment includes any options or restricted stock that would be outstanding as dilutive instruments using the treasury stock method and the weighted average number of common shares that would be outstanding if the convertible notes were converted into common stock on the original issue date based on the number of days such common shares would have been outstanding in the reporting period, until the effect of these adjustments are anti-dilutive.
(8) In those periods in which GAAP net (loss) income is positive and adjusted net (loss) income is negative, this adjustment excludes any options or restricted stock that would be outstanding as dilutive instruments using the treasury stock method and the weighted average number of common shares that would be outstanding if the convertible notes were converted into common stock on the original issue date based on the number of days such common shares would have been outstanding in the reporting period.
NeoGenomics, Inc. | 9490 NeoGenomics Way Fort Myers, FL 33912

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Reconciliation of Non-GAAP Financial Guidance to Corresponding GAAP Measures
(Unaudited, in thousands, except per share amounts)
GAAP net loss in 2026 will be impacted by certain charges, including: (i) expense related to the amortization of intangible assets, (ii) stock-based compensation, and (iii) other one-time expenses. These charges have been included in GAAP net loss available to stockholders and GAAP net loss per share; however, they have been removed from adjusted net loss and adjusted diluted net loss per share.
The following table reconciles the Company’s 2026 outlook for net loss and EPS to the corresponding non-GAAP measures of adjusted net loss, adjusted EBITDA, and adjusted diluted EPS:
Year Ended December 31, 2026
Low Range
High Range
Net loss (GAAP)$(63,000)$(50,000)
Amortization of intangibles30,000 30,000 
Stock-based compensation43,000 40,000 
Other one-time expenses11,000 7,000 
Adjusted net income (non-GAAP)21,000 27,000 
Interest and taxes(5,000)(6,000)
Depreciation39,000 36,000 
Adjusted EBITDA (non-GAAP)$55,000 $57,000 
Net loss per diluted share (GAAP)$(0.48)$(0.38)
Adjustments to net loss per diluted share:
Amortization of intangibles0.23 0.23 
Stock-based compensation0.33 0.31 
Other one-time expenses0.08 0.05 
Rounding and impact of diluted shares in adjusted diluted shares(1)
— — 
Adjusted diluted EPS(2) (non-GAAP)
$0.16 $0.21 
Weighted average assumed shares outstanding in 2026:
Diluted shares (GAAP)130,000 130,000 
Options, restricted stock, and converted shares not included in diluted shares(2)
— — 
Adjusted diluted shares outstanding (non-GAAP)130,000 130,000 
_________________
(1) This adjustment is for rounding and, in those periods in which GAAP net (loss) income is negative and adjusted net (loss) income is positive, also compensates for the effects of additional diluted shares included in adjusted diluted shares outstanding for the treasury stock impact of outstanding stock options and restricted stock and the if-converted impact of convertible notes.
(2) For those periods in which GAAP net (loss) income is negative and adjusted net (loss) income is positive, this adjustment includes any options or restricted stock that would be outstanding as dilutive instruments using the treasury stock method and the weighted average number of shares that would be outstanding if the convertible notes were converted into common stock on the original issue date based on the number of days such shares would have been outstanding in the reporting period, until the effect of these adjustments are anti-dilutive.

NeoGenomics, Inc. | 9490 NeoGenomics Way Fort Myers, FL 33912

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Supplemental Information
Clinical Tests Performed and Revenue
(Unaudited)

Three Months Ended December 31,Years Ended December 31,
20252024% Change20252024% Change
Clinical including Pathline(1):
Number of tests performed356,136 321,679 10.7 %1,399,703 1,248,740 12.1 %
Average revenue/test$488 $465 4.9 %$471 $457 3.1 %
Clinical excluding Pathline(2):
Number of tests performed342,586 321,679 6.5 %1,358,969 1,248,740 8.8 %
Average revenue/test$496 $465 6.7 %$476 $457 4.2 %
_________________
(1) Excludes tests and revenue related to non-clinical activity.
(2) Excludes tests and revenue related to Pathline and non-clinical activity.
NeoGenomics, Inc. | 9490 NeoGenomics Way Fort Myers, FL 33912

FAQ

How did NeoGenomics (NEO) perform in Q4 2025?

NeoGenomics grew fourth-quarter 2025 revenue 11% to $190.2 million, driven by higher clinical volumes and more high-value tests. Net loss improved to $9.9 million from $15.3 million, while adjusted EBITDA increased to a positive $13.4 million from $11.9 million.

What were NeoGenomics' full-year 2025 financial results?

For 2025, NeoGenomics reported revenue of $727.3 million, up 10% from 2024, reflecting stronger test volumes and mix. GAAP net loss widened to $108.0 million, but non-GAAP adjusted EBITDA improved to $43.4 million, and adjusted net income reached $14.8 million versus $14.3 million in 2024.

What financial guidance did NeoGenomics (NEO) give for 2026?

NeoGenomics expects 2026 revenue between $793 million and $801 million, implying 9–10% year-over-year growth. The company projects a smaller GAAP net loss of $50–63 million and non-GAAP adjusted EBITDA between $55 million and $57 million, above 2025 levels.

How is NeoGenomics' profitability trending based on 2025 results?

NeoGenomics remains loss-making on a GAAP basis, with a 2025 net loss of $108.0 million, up from $78.7 million. However, quarterly net loss narrowed in Q4, and non-GAAP adjusted EBITDA improved to $43.4 million, indicating gradual underlying operating improvement despite restructuring, impairment, and litigation-related costs.

What role did non-GAAP measures play in NeoGenomics' 2025 reporting?

NeoGenomics highlighted non-GAAP metrics such as Adjusted EBITDA, Adjusted Gross Profit Margin, and Adjusted Net Income to strip out amortization, stock-based compensation, restructuring, impairment, and IP litigation costs. These measures showed positive adjusted EBITDA of $43.4 million and adjusted net income of $14.8 million in 2025.

What strategic developments did NeoGenomics (NEO) report around RaDaR ST?

NeoGenomics noted a successful resolution of RaDaR ST patent litigation and highlighted the imminent clinical launch of its RaDaR ST MRD assay. Management described this as expanding its advanced testing menu and addressing a large molecular residual disease monitoring market opportunity over the longer term.

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Diagnostics & Research
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