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Nurix Therapeutics, Inc. SEC Filings

NRIX NASDAQ

Welcome to our dedicated page for Nurix Therapeutics SEC filings (Ticker: NRIX), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.

Buried inside Nurix Therapeutics’ dense biotechnology filings are clues about BTK degrader trial costs, CBL-B inhibitor milestones, and partnership revenue streams. For many, decoding a 300-page report feels impossible. That’s why this page goes beyond a simple document list.

Stock Titan’s AI reads every Nurix Therapeutics annual report 10-K simplified, quarterly earnings report 10-Q filing, and 8-K material events explained the moment they hit EDGAR. Our technology highlights how R&D spending shifts with each clinical phase and pinpoints collaboration payments that can move the stock before earnings day.

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Whether you’re scanning a single footnote or benchmarking pipeline spend, you’ll find Nurix Therapeutics SEC filings explained simply—complete, current, and immediately actionable.

Rhea-AI Summary

Nurix Therapeutics, Inc. (Nasdaq: NRIX) – Fiscal Q2 2025 10-Q highlights

  • Revenue inflection: Total Q2 revenue jumped to $44.1 million (up 264% YoY) driven by a $30 million license fee from Sanofi and higher collaboration revenue from existing partnerships with Sanofi, Gilead and Pfizer.
  • Operating costs accelerate: R&D expense expanded 60% YoY to $78.1 million as the company advanced clinical programs (NX-5948, NX-2127, NX-1607) and DAC discovery work; G&A rose 22% to $14.3 million.
  • Loss narrows modestly for the quarter: Net loss was $43.5 million (-$0.52 per share) versus $44.5 million (-$0.71) a year ago, helped by the one-time license payment and a larger share count. For the six-month period, however, the loss widened to $99.8 million.
  • Cash runway: Cash, cash equivalents and marketable securities totaled $485.8 million at 31 May 2025, down from $609.6 million at FY-end. Operating cash burn reached $124.2 million in the first half. Management believes existing liquidity funds operations for at least 12 months.
  • Collaboration momentum: • Gilead extended the research term by two years, triggering a $15 million payment.
    • Sanofi exercised two target license options, providing $30 million.
    • Pfizer collaboration produced $10 million in research milestones to date.
  • Equity activity: 76.4 million shares outstanding after ATM issuances; stockholders’ equity fell to $447.6 million from $527.0 million on higher deficit.

Overall, Nurix continues to monetize its DEL-AI platform through partner payments while accelerating internal R&D, resulting in higher cash burn and sustained losses.

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FAQ

What is the current stock price of Nurix Therapeutics (NRIX)?

The current stock price of Nurix Therapeutics (NRIX) is $12.44 as of July 11, 2025.

What is the market cap of Nurix Therapeutics (NRIX)?

The market cap of Nurix Therapeutics (NRIX) is approximately 970.5M.

What is the core focus of Nurix Therapeutics?

Nurix Therapeutics focuses on discovering and developing innovative small molecule therapies that leverage targeted protein degradation to treat cancer, inflammatory, and immune disorders.

How does the DELigase platform work?

The DELigase platform integrates DNA-encoded library screening with advanced chemistry and structure-based design to identify modulators of the ubiquitin proteasome system, allowing for selective control over E3 ligases.

What therapeutic areas does Nurix target?

Nurix targets multiple therapeutic areas including oncology, autoimmune diseases, and inflammatory conditions by focusing on the modulation of protein levels through degradation or stabilization mechanisms.

What makes Nurix's approach different from traditional therapies?

Unlike traditional kinase inhibitors that block protein function, Nurix’s approach aims to eliminate pathogenic proteins through targeted degradation, potentially overcoming resistance seen with conventional treatments.

Who are the key collaborators of Nurix Therapeutics?

Nurix has established strategic partnerships with major pharmaceutical companies such as Gilead, Sanofi, and Pfizer, which enhance its research capabilities and support the advancement of its clinical programs.

What role do BTK degraders play in Nurix's pipeline?

BTK degraders are a major focus in Nurix’s clinical pipeline; they are designed to target and degrade Bruton’s tyrosine kinase, a key protein in B-cell signaling, thereby offering potential benefits in treating B-cell malignancies.

How does Nurix integrate new technologies into its research?

Nurix leverages artificial intelligence and machine learning alongside its DELigase platform to improve candidate selection and expedite drug discovery, demonstrating its commitment to continuous innovation.

What is the significance of targeting E3 ligases?

Targeting E3 ligases offers a novel therapeutic approach by modulating the degradation of proteins that are critical to cell regulation, which can result in more durable responses in diseases that are difficult to treat.
Nurix Therapeutics, Inc.

NASDAQ:NRIX

NRIX Rankings

NRIX Stock Data

970.48M
74.42M
1.36%
110.53%
15.28%
Biotechnology
Pharmaceutical Preparations
Link
United States
SAN FRANCISCO