STOCK TITAN

Nuvation Bio (NUVB) CMO exercises options and sells 50,000 shares

Filing Impact
(Neutral)
Filing Sentiment
(Neutral)
Form Type
4

Rhea-AI Filing Summary

Nuvation Bio Inc. chief medical officer Dongfang Liu reported an exercise-and-sell transaction in Class A common stock. Liu exercised stock options to acquire 50,000 shares at $1.94 per share, then sold 50,000 shares in open-market trades at a weighted-average price of $5.02 per share.

The sales, executed at prices ranging from $5.00 to $5.07, were made under a pre-arranged Rule 10b5-1 trading plan dated December 4, 2025. After these transactions, Liu holds 18,000 shares of Class A common stock and 430,000 stock options expiring on February 27, 2033.

Positive

  • None.

Negative

  • None.
Insider Liu Dongfang
Role CHIEF MEDICAL OFFICER
Sold 50,000 shs ($251K)
Type Security Shares Price Value
Exercise Stock Option (Right to Buy) 50,000 $0.00 --
Exercise Class A Common Stock 50,000 $1.94 $97K
Sale Class A Common Stock 50,000 $5.02 $251K
Holdings After Transaction: Stock Option (Right to Buy) — 430,000 shares (Direct, null); Class A Common Stock — 68,000 shares (Direct, null)
Footnotes (1)
  1. Shares sold pursuant to a 10b5-1 plan dated December 4, 2025. Price reported is a weighted-average sales price. The shares were sold at prices ranging from $5.00 to $5.07. The Reporting Person will provide, upon request, to the SEC, the Issuer or security holder of the Issuer, full information regarding the number of shares sold at each separate price. Option vests as to 25% on February 28, 2024, and monthly thereafter over the following 36 months, subject to Reporting Person's continuous service on each such vesting date
Shares sold 50,000 shares Class A common stock sold in open market on April 17, 2026
Sale price $5.02 per share Weighted-average sale price; trades ranged $5.00–$5.07
Options exercised 50,000 shares Options exercised into Class A common stock on April 17, 2026
Option exercise price $1.94 per share Strike price for exercised stock options
Shares held after 18,000 shares Direct Class A common stock holdings after transactions
Options remaining 430,000 options Stock options outstanding after exercise, expiring February 27, 2033
Net share change 50,000 shares Net-sell shares according to transaction summary
Rule 10b5-1 plan regulatory
"Shares sold pursuant to a 10b5-1 plan dated December 4, 2025."
A Rule 10b5-1 plan is a prearranged, written schedule that lets corporate insiders buy or sell company stock at set times or amounts, even if they later learn material nonpublic information. Think of it like setting an automatic thermostat for trades: it creates a clear record that trades were planned in advance, reducing the risk of insider-trading accusations and helping investors trust that insider transactions are routine rather than based on secret information.
weighted-average sales price financial
"Price reported is a weighted-average sales price."
Stock Option (Right to Buy) financial
"Security title listed as Stock Option (Right to Buy)."
vesting financial
"Option vests as to 25% on February 28, 2024, and monthly thereafter."
Vesting is the process by which you earn full ownership of something, like company stock or a retirement benefit, over time. It’s like earning the right to keep a gift piece by piece the longer you stay with a company, making sure employees stay committed before they receive all the benefits.
derivative security financial
"Exercise or conversion of derivative security."
A derivative security is a financial contract whose value comes from the price or performance of something else, such as a stock, bond, commodity, or market index. For investors it acts like an insurance policy or a wager: it can be used to protect against losses, lock in prices, or amplify gains and losses, so it can change a portfolio’s risk and potential return without owning the underlying asset directly.
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Liu Dongfang

(Last)(First)(Middle)
C/O NUVATION BIO INC.
1500 BROADWAY, SUITE 1401

(Street)
NEW YORK NEW YORK 10036

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Nuvation Bio Inc. [ NUVB ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director10% Owner
XOfficer (give title below)Other (specify below)
CHIEF MEDICAL OFFICER
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
04/17/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Class A Common Stock04/17/2026M50,000A$1.9468,000D
Class A Common Stock04/17/2026S(1)50,000D$5.02(2)18,000D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Option (Right to Buy)$1.9404/17/2026M50,000 (3)02/27/2033Class A Common Stock50,000$0430,000D
Explanation of Responses:
1. Shares sold pursuant to a 10b5-1 plan dated December 4, 2025.
2. Price reported is a weighted-average sales price. The shares were sold at prices ranging from $5.00 to $5.07. The Reporting Person will provide, upon request, to the SEC, the Issuer or security holder of the Issuer, full information regarding the number of shares sold at each separate price.
3. Option vests as to 25% on February 28, 2024, and monthly thereafter over the following 36 months, subject to Reporting Person's continuous service on each such vesting date
/s/ Stephen Dang, Attorney-in-Fact04/21/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What insider transaction did Nuvation Bio (NUVB) report for Dongfang Liu?

Nuvation Bio reported that chief medical officer Dongfang Liu exercised options for 50,000 Class A shares at $1.94 and sold 50,000 shares in open-market trades at a weighted-average price of $5.02, as disclosed in the Form 4 insider filing.

At what prices did NUVB’s Dongfang Liu sell Nuvation Bio shares?

Liu sold 50,000 Nuvation Bio Class A shares at a weighted-average price of $5.02. According to the filing, individual trades occurred within a price range from $5.00 to $5.07 per share, with full trade-by-trade details available on request from relevant parties.

Was the NUVB insider sale by Dongfang Liu under a 10b5-1 plan?

Yes. The filing states that Dongfang Liu’s 50,000-share sale was executed pursuant to a Rule 10b5-1 trading plan dated December 4, 2025. Such pre-arranged plans automate trading and can reduce the significance of transaction timing for interpreting insider sentiment.

How many Nuvation Bio (NUVB) shares does Dongfang Liu hold after the Form 4?

Following the reported transactions, Dongfang Liu directly holds 18,000 shares of Nuvation Bio Class A common stock. The filing also shows continued derivative exposure through 430,000 stock options, providing substantial potential equity participation alongside the reduced direct share position.

What stock options does NUVB’s Dongfang Liu retain after exercising 50,000 options?

After exercising 50,000 options, Liu still holds 430,000 stock options with a $1.94 exercise price. A footnote explains these options vest 25% on February 28, 2024, then monthly over 36 months, and they are scheduled to expire on February 27, 2033.