OKYO Pharma (NASDAQ: OKYO) CDO buys 30,980 shares at $1.59
Filing Impact
Filing Sentiment
Form Type
6-K
Rhea-AI Filing Summary
OKYO Pharma Limited reports that its Chief Development Officer and Director, Gary Jacob, has acquired 30,980 ordinary shares on Nasdaq at $1.59 per share, increasing his holding to 108,920 shares. The company highlights its lead candidate urcosimod, which has shown anti-inflammatory and pain‑reducing effects in preclinical models and positive pain‑reduction data in an 18‑subject Phase 2a neuropathic corneal pain trial and a prior 240‑subject dry eye disease trial. OKYO recently completed a successful Phase 2 trial in neuropathic corneal pain and plans a ~150‑subject Phase 2b/3 multiple‑dose study in the first half of this year.
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FAQ
What is urcosimod and what eye conditions is OKYO (OKYO) targeting?
Urcosimod is a lipid-conjugated chemerin peptide agonist of the ChemR23 receptor found on ocular immune and nerve cells. OKYO is developing it for neuropathic corneal pain and inflammatory eye diseases, aiming to reduce pain and inflammation in these difficult-to-treat conditions.
What clinical trial results has OKYO (OKYO) reported for urcosimod in neuropathic corneal pain?
OKYO reported positive neuropathic corneal pain reduction data from a randomized, placebo-controlled, double-masked Phase 2a trial involving 18 subjects. These results support further development of urcosimod as a potential treatment option for patients suffering from neuropathic corneal pain.
How has urcosimod performed in dry eye disease studies for OKYO (OKYO)?
Urcosimod showed significant pain reduction in a 240-subject Phase 2, multi-center, double-masked, placebo-controlled dry eye disease trial. These findings help justify its development for neuropathic corneal pain, where ocular surface inflammation and nerve-related pain are closely linked.
What future clinical plans does OKYO (OKYO) have for urcosimod?
OKYO plans to initiate a ~150-subject Phase 2b/3 multiple-dose study of urcosimod in neuropathic corneal pain in the first half of this year. This larger trial is intended to further evaluate efficacy and safety in a more advanced development stage.
How does OKYO (OKYO) describe its overall business focus?
OKYO Pharma describes itself as a clinical-stage biopharmaceutical company developing innovative therapies for neuropathic corneal pain and inflammatory eye diseases. Its ordinary shares trade on the Nasdaq Capital Market, and urcosimod is its flagship drug candidate in development.
