FMR LLC Reports 12.5% Stake in OLEMA Pharmaceuticals

OLEMA PHARMACEUTICALS INC reports FMR LLC beneficial ownership of 9,998,059.72 shares of common stock, representing 12.5% of the class.

Rhea-AI Filing Summary

OLEMA PHARMACEUTICALS INC reports FMR LLC beneficial ownership of 9,998,059.72 shares of common stock, representing 12.5% of the class. The filing (Amendment No. 1 to a Schedule 13G) shows FMR LLC has sole dispositive power for 9,998,059.72 shares and sole voting power of 9,985,722 shares.

Abigail P. Johnson is also listed with sole dispositive power for 9,998,059.72 shares. The filing notes that one or more other persons have rights to dividends or proceeds but no other single person holds over 5%.

Insights

Institutional Ownership Analyst

FMR LLC holds a sizable 12.5% stake in OLEMA common stock.

FMR LLC reports beneficial ownership of 9,998,059.72 shares with sole dispositive authority and near‑sole voting authority (9,985,722). This indicates a significant passive position reported under Schedule 13G/A rather than an activist 13D filing.

Timing: the cover shows 02/27/2026 and signatures dated 03/05/2026. Subsequent filings may disclose changes in holdings or voting arrangements.

Proxy & Governance Specialist

Ownership is reported with standard disclosures about third‑party dividend/proceeds rights.

The filing explicitly states that one or more other persons are known to have rights to dividends or sale proceeds, but no single other person exceeds 5%. This language is typical for investment managers holding securities for multiple accounts.

Investors may watch future amendment filings for any change in percent ownership or voting power.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What stake does FMR LLC report in OLEMA (OLMA)?

FMR LLC reports beneficial ownership of 9,998,059.72 shares, equal to 12.5% of OLEMA common stock. The filing lists sole dispositive power for the same share count and sole voting power of 9,985,722.

Does Abigail P. Johnson have reported control over OLMA shares?

Abigail P. Johnson is listed with sole dispositive power over 9,998,059.72 shares of OLMA common stock. The filing shows her as an authorized person under the power of attorney executed for these disclosures.

When were the Schedule 13G/A signatures dated for OLMA?

The signatures on the amendment are dated 03/05/2026. The cover references 02/27/2026 as the reporting date, indicating the filing was amended and signed in early March 2026.

Is anyone else reported to hold more than 5% of OLMA in this filing?

The filing states that one or more other persons have rights to dividends or proceeds, but explicitly that no other single person holds more than 5% of OLMA common stock.

What powers does FMR LLC report for these OLMA shares?

FMR LLC reports sole dispositive power for 9,998,059.72 shares and sole voting power for 9,985,722 shares. Shared voting and dispositive powers are reported as 0.00.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 03/06/2026 - 10:05 AM Learn about SEC filing dates

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 1)

OLEMA PHARMACEUTICALS INC

(Name of Issuer)

COMMON STOCK

(Title of Class of Securities)

02/27/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

SCHEDULE 13G

CUSIP Number(s):

1

Names of Reporting Persons

FMR LLC

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 9,985,722.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 9,998,059.72
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

9,998,059.72

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

12.5 %

12

Type of Reporting Person (See Instructions)

HC

SCHEDULE 13G

CUSIP Number(s):

1

Names of Reporting Persons

Abigail P. Johnson

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 9,998,059.72
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

9,998,059.72

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

12.5 %

12

Type of Reporting Person (See Instructions)

IN

SCHEDULE 13G

Item 1.
(a)	Name of issuer: OLEMA PHARMACEUTICALS INC
(b)	Address of issuer's principal executive offices: 780 BRANNAN STREET,SAN FRANCISCO,CA,US,94103
Item 2.
(a)	Name of person filing: FMR LLC
(b)	Address or principal business office or, if none, residence: 245 Summer Street, Boston, Massachusetts 02210
(c)	Citizenship: Not applicable
(d)	Title of class of securities: COMMON STOCK
(e)	CUSIP No.: 68062P106
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: 9998059.72
(b)	Percent of class: 12.5 %
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: Please see the responses to Items 5 and 6 on the cover page.
	(ii) Shared power to vote or to direct the vote: 0.00
	(iii) Sole power to dispose or to direct the disposition of: 9998059.72
	(iv) Shared power to dispose or to direct the disposition of: 0.00
Item 5.	Ownership of 5 Percent or Less of a Class.
	Not Applicable
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required. One or more other persons are known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, the COMMON STOCK of OLEMA PHARMACEUTICALS INC. No one other person's interest in the COMMON STOCK of OLEMA PHARMACEUTICALS INC is more than five percent of the total outstanding COMMON STOCK.
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	If a parent holding company has filed this schedule, pursuant to Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary. See attached Exhibit 99.
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

FMR LLC

Signature:	Stephanie J. Brown
Name/Title:	Duly authorized under Power of Attorney effective as of January 3, 2023, by and on behalf of FMR LLC and its direct and indirect subsidiaries*
Date:	03/05/2026

Abigail P. Johnson

Signature:	Stephanie J. Brown
Name/Title:	Duly authorized under Power of Attorney effective as of January 26, 2023, by and on behalf of Abigail P. Johnson**
Date:	03/05/2026

Comments accompanying signature: * This power of attorney is incorporated herein by reference to Exhibit 24 to the Schedule 13G filed by FMR LLC on January 10, 2023, accession number: 0000315066-23-000003. ** This power of attorney is incorporated herein by reference to Exhibit 24 to the Schedule 13G filed by FMR LLC on January 31, 2023, accession number: 0000315066-23-000038.

Exhibit Information

Please see Exhibit 99 for 13d-1(k) (1) agreement.