[25] Opthea Ltd SEC Filing

Rhea-AI Filing Summary

Opthea Limited filed a Form 25 to remove its American Depositary Shares from listing and/or registration under Section 12(b) of the Securities Exchange Act of 1934. The securities are ADSs, each representing eight ordinary shares, previously listed on The Nasdaq Global Select Market. The notification was signed by Chief Executive Officer Jeremy Levin on November 10, 2025.

Positive

• None.

Negative

• Delisting notice filed: Form 25 submitted to remove ADSs from The Nasdaq Global Select Market under Section 12(b).

Insights

Capital markets analyst

Form 25 signals removal of Opthea ADSs from Nasdaq listing.

Opthea Limited submitted a Form 25, which is the formal step to remove a security from exchange listing and/or Section 12(b) registration. The filing identifies the class as American Depositary Shares, each representing eight ordinary shares, and the prior venue as The Nasdaq Global Select Market.

This action typically precedes or reflects a delisting outcome. The filing itself does not provide reasons, proceeds, or alternatives. Future disclosures in company filings may specify subsequent trading arrangements or regulatory status.

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 25

NOTIFICATION OF REMOVAL FROM LISTING

AND/OR REGISTRATION UNDER SECTION 12(b)

OF THE SECURITIES EXCHANGE ACT OF 1934

Commission File Number 001-39621

Opthea Limited

The Nasdaq Global Select Market

(Exact name of Issuer as specified in its charter, and name of Exchange where security is listed and/or registered)

C/- Prime Company Compliance, Level 9

505 Little Collins Street

Melbourne, VIC 3000

Australia

+ 61 3 9826 0399

(Address, including zip code, and telephone number, including area code, of Issuer’s principal executive offices)

American Depositary Shares, each representing eight ordinary shares, no par value

(Description of class of securities)

Please place an X in the box to designate the rule provision relied upon to strike the class of securities from listing and registration:

☐ 17 CFR 240.12d2-2(a)(1)

☐ 17 CFR 240.12d2-2(a)(2)

☐ 17 CFR 240.12d2-2(a)(3)

☐ 17 CFR 240.12d2-2(a)(4)

☐ Pursuant to 17 CFR 240.12d2-2(b), the Exchange has complied with its rules to strike the class of securities from listing and/or withdraw registration on the Exchange.

☒ Pursuant to 17 CFR 240.12d2-2(c), the Issuer has complied with the rules of the Exchange and the requirements of 17 CFR 240.12d2-2(c) governing the voluntary withdrawal of the class of securities from listing and registration on the Exchange.

As of the date hereof, the Issuer does not have an audit committee that meets the audit committee composition requirements set forth in Nasdaq Listing Rule 5605(c)(2).

Pursuant to the requirements of the Securities Exchange Act of 1934, Opthea Limited certifies that it has reasonable grounds to believe that it meets all of the requirements for filing the Form 25 and has caused this notification to be signed on its behalf by the undersigned duly authorized person.

				Opthea Limited
Date: November 10, 2025				By:		/s/ Jeremy Levin
				Name:		Jeremy Levin
				Title:		Chief Executive Officer

FAQ

What did Opthea (OPT) file?

Opthea filed a Form 25 to remove its securities from listing and/or registration under Section 12(b).

Which securities are affected for OPT?

The filing covers American Depositary Shares, each representing eight ordinary shares.

Where were Opthea’s ADSs listed?

They were listed on The Nasdaq Global Select Market.

Who signed the Form 25 for Opthea?

It was signed by Jeremy Levin, Chief Executive Officer.

When was the Form 25 signed?

The notification was signed on November 10, 2025.

What does a Form 25 generally indicate?

It is the formal notification to remove a security from exchange listing and/or Section 12(b) registration.