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Oruka Therapeutics (ORKA) COO sells 5,000 shares and exercises 5,000-share warrant

Filing Impact
(Neutral)
Filing Sentiment
(Neutral)
Form Type
4

Rhea-AI Filing Summary

Oruka Therapeutics, Inc. Chief Operating Officer Laura Lee Sandler reported multiple transactions in the company’s common stock. On May 1, 2026, she completed open-market sales totaling 5,000 shares at weighted average prices within ranges from $62.33 to $67.20 per share under a pre-established Rule 10b5-1 trading plan.

On the same date, she also exercised employee warrants to acquire 5,000 shares of common stock at an exercise price of $7.80 per share. The warrant covers 5,000 underlying shares, vests over time beginning April 3, 2025, and is scheduled to expire on July 14, 2034.

Positive

  • None.

Negative

  • None.
Insider Sandler Laura Lee
Role Chief Operating Officer
Sold 5,000 shs ($319K)
Type Security Shares Price Value
Exercise Employee Warrant (right to buy) 5,000 $0.00 --
Exercise Common Stock 5,000 $7.80 $39K
Sale Common Stock 2,200 $62.5843 $138K
Sale Common Stock 1,800 $64.1488 $115K
Sale Common Stock 300 $65.10 $20K
Sale Common Stock 400 $66.055 $26K
Sale Common Stock 200 $67.155 $13K
Sale Common Stock 100 $68.48 $7K
Holdings After Transaction: Employee Warrant (right to buy) — 84,996 shares (Direct, null); Common Stock — 241,984 shares (Direct, null)
Footnotes (1)
  1. The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $62.33 to $62.83, inclusive. The reporting person undertakes to provide to Oruka Therapeutics, Inc., any security holder of Oruka Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2), (3), (4), (5) and (6) to this Form 4. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $63.59 to $64.55, inclusive. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $64.85 to $65.28, inclusive. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $65.85 to $66.23, inclusive. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $67.11 to $67.20, inclusive. The warrant vests as to 1/4 of the underlying shares on April 3, 2025 and as to 1/48 of the underlying shares monthly from April 3, 2025.
Shares sold 5,000 shares Total common stock sold on May 1, 2026 in open-market transactions
Shares acquired via warrant exercise 5,000 shares Common stock obtained by exercising employee warrant on May 1, 2026
Warrant exercise price $7.80 per share Exercise price for employee warrant covering 5,000 common shares
Sale price ranges $62.33–$67.20 per share Weighted-average sale prices across multiple transactions noted in footnotes
Warrant expiration July 14, 2034 Scheduled expiration date of employee warrant exercised
Net share change from buy/sell 5,000 shares net sold Transaction summary netBuySellShares for this Form 4
Rule 10b5-1 trading plan regulatory
"The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan"
A Rule 10b5-1 trading plan is a pre-arranged schedule that allows company insiders to buy or sell stock at specific times, even if they have inside information. It helps prevent accusations of unfair trading by making these transactions look planned and transparent, rather than sneaky or illegal.
weighted average price financial
"The price reported in Column 4 is a weighted average price"
Weighted average price is the average price of a security where each trade or component is counted according to its size, so bigger trades pull the average more than smaller ones. Think of it like calculating the average cost of a grocery haul where items you bought more of have greater influence on the final per-item cost. Investors use it to understand the true average price paid or received, judge execution quality, and compare trading performance against market movement.
Employee Warrant (right to buy) financial
"Employee Warrant (right to buy) ... underlying security title: Common Stock"
derivative security financial
"Exercise or conversion of derivative security"
A derivative security is a financial contract whose value comes from the price or performance of something else, such as a stock, bond, commodity, or market index. For investors it acts like an insurance policy or a wager: it can be used to protect against losses, lock in prices, or amplify gains and losses, so it can change a portfolio’s risk and potential return without owning the underlying asset directly.
open-market sale financial
"transaction_action: open-market sale"
An open-market sale is when a shareholder sells existing shares directly on a public exchange to any willing buyer, rather than through a private deal. Think of it like putting goods on a busy market stall where price is set by supply and demand; for investors it matters because such sales increase available supply, can put short-term downward pressure on the stock price, and signal changes in liquidity or investor confidence.
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Sandler Laura Lee

(Last)(First)(Middle)
C/O ORUKA THERAPEUTICS, INC.
855 OAK GROVE AVE., SUITE 100

(Street)
MENLO PARK CALIFORNIA 94025

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Oruka Therapeutics, Inc. [ ORKA ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director10% Owner
XOfficer (give title below)Other (specify below)
Chief Operating Officer
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
05/01/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock05/01/2026M5,000A$7.8241,984D
Common Stock05/01/2026S(1)2,200D$62.5843(2)239,784D
Common Stock05/01/2026S(1)1,800D$64.1488(3)237,984D
Common Stock05/01/2026S(1)300D$65.1(4)237,684D
Common Stock05/01/2026S(1)400D$66.055(5)237,284D
Common Stock05/01/2026S(1)200D$67.155(6)237,084D
Common Stock05/01/2026S(1)100D$68.48236,984D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Employee Warrant (right to buy)$7.805/01/2026M5,000 (7)07/14/2034Common Stock5,000$084,996D
Explanation of Responses:
1. The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025.
2. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $62.33 to $62.83, inclusive. The reporting person undertakes to provide to Oruka Therapeutics, Inc., any security holder of Oruka Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2), (3), (4), (5) and (6) to this Form 4.
3. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $63.59 to $64.55, inclusive.
4. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $64.85 to $65.28, inclusive.
5. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $65.85 to $66.23, inclusive.
6. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $67.11 to $67.20, inclusive.
7. The warrant vests as to 1/4 of the underlying shares on April 3, 2025 and as to 1/48 of the underlying shares monthly from April 3, 2025.
/s/ Paul Quinlan, as attorney-in-fact for Laura Sandler05/01/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What insider transactions did ORKA’s COO Laura Lee Sandler report on this Form 4?

Laura Lee Sandler reported both sales and an option exercise. She sold a total of 5,000 common shares in open-market transactions and exercised employee warrants to acquire 5,000 common shares at an exercise price of $7.80 per share.

At what prices did the ORKA COO sell Oruka Therapeutics common stock?

The reported sale prices are weighted averages across multiple trades. According to footnotes, shares were sold in ranges including $62.33–$62.83, $63.59–$64.55, $64.85–$65.28, $65.85–$66.23, and $67.11–$67.20 per share.

Was the Oruka Therapeutics (ORKA) COO’s stock sale pre-planned under a Rule 10b5-1 plan?

Yes. A footnote states the sales were effected pursuant to a Rule 10b5-1 trading plan entered into on September 19, 2025. Such plans pre-schedule trades, indicating these sales followed an established trading arrangement rather than ad hoc market timing.

How many Oruka Therapeutics shares did Laura Lee Sandler sell versus acquire in this filing?

The transaction summary shows 5,000 shares sold in open-market transactions and 5,000 shares acquired through exercising an employee warrant. This results in a net reported share change of 5,000 more shares sold than acquired in this Form 4.

What are the key terms of the employee warrant exercised by the ORKA COO?

The employee warrant covers 5,000 underlying common shares at an exercise price of $7.80 per share. It vests as to one quarter of the shares on April 3, 2025, then in monthly installments, and is scheduled to expire on July 14, 2034.

Does the Form 4 indicate any remaining derivative position for the Oruka Therapeutics COO?

The derivative section shows an Employee Warrant (right to buy) for 5,000 shares being exercised. The derivative summary in the data is empty after this, which indicates no additional derivative positions are reported in this particular filing excerpt.