Janus Henderson reports 772,314 shares (4.7%) in OSI Systems

OSI Systems, Inc. Schedule 13G/A reports that Janus Henderson Group plc, through affiliated asset managers, beneficially owns 772,314 shares of OSI Systems common stock, representing 4.7% of the class.

Rhea-AI Filing Summary

OSI Systems, Inc. Schedule 13G/A reports that Janus Henderson Group plc, through affiliated asset managers, beneficially owns 772,314 shares of OSI Systems common stock, representing 4.7% of the class. The filing states the asset managers exercise shared voting and dispositive power over those shares. The filing is signed on 5/15/2026. The report notes the Managed Portfolios hold the economic rights to dividends and sale proceeds, while the Asset Managers disclaim rights to receive dividends or sale proceeds personally.

Insights

Institutional Ownership Analyst

Large asset manager disclosed a 4.7% beneficial stake via discretionary mandates.

Janus Henderson Group plc is reported as the ultimate parent of multiple registered asset managers that collectively exercise shared voting and dispositive power over 772,314 shares of OSI Systems common stock. The filing attributes beneficial ownership to the Asset Managers because they exercise discretion for Managed Portfolios.

The filing clarifies that the Managed Portfolios hold dividend and sale proceeds rights; the Asset Managers disclaim those economic rights. Subsequent public filings would show any changes in holdings.

Compliance & Reporting Specialist

Schedule 13G/A classifies the position as passive beneficial ownership by a parent holding company.

The schedule lists the parent, Janus Henderson Group plc, and identifies multiple subsidiary Asset Managers as exercising voting/dispositive discretion, consistent with reporting as a parent of investment advisers. The form references Exhibit 99 for Item 7 subsidiary detail.

Signature block shows the report was signed by the Head of North America Compliance on 5/15/2026, which anchors the filing's certification date.

Key Figures

Filed reporting period: 03/31/2026 Beneficial ownership: 772,314 shares Percent of class: 4.7% +3 more

6 metrics

Filed reporting period 03/31/2026 cover date shown on filing page

Beneficial ownership 772,314 shares Amount beneficially owned by Janus Henderson Group plc via Asset Managers

Percent of class 4.7% Percent of OSI Systems common stock class reported

CUSIP 671044105 OSI Systems common stock CUSIP listed on form

Shared voting power 772,314 shares Number with shared power to vote as reported

Shared dispositive power 772,314 shares Number with shared power to dispose as reported

Key Terms

beneficially owned, dispositive power, Managed Portfolios

3 terms

beneficially owned regulatory

"may be deemed to be the beneficial owner of 772,314 common stock"

Beneficially owned describes securities or assets where a person has the economic rights and control—such as the right to receive dividends and to direct voting—even if legal title is held in another name. Think of it like having the keys and using a car that’s registered to someone else: you get the benefits and make decisions. Investors care because beneficial ownership reveals who truly controls value and voting power, affecting corporate decisions and takeover dynamics.

dispositive power regulatory

"Shared Dispositive Power 772,314.00"

Dispositive power is the authority to decide the final outcome of an asset, legal claim, contract, or corporate action — in effect the power to dispose of or resolve something. For investors it matters because whoever holds that authority can determine who gets paid, who controls an asset or vote, and how risks and returns are allocated; think of it like holding the key that lets you lock in the winner or loser in a deal.

Managed Portfolios financial

"collectively referred to herein as Managed Portfolios"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What stake does Janus Henderson Group plc report in OSIS?

Janus Henderson Group plc reports beneficial ownership of 772,314 shares of OSI Systems common stock, equal to 4.7% of the class. The position is held via affiliated asset managers exercising discretion for client Managed Portfolios.

Does Janus Henderson have voting or sale rights for the OSIS shares?

The filing states the Asset Managers have shared voting power and shared dispositive power over the 772,314 shares. It also clarifies that the Managed Portfolios hold the economic rights to dividends and proceeds.

Who filed the Schedule 13G/A and when was it signed?

The Schedule 13G/A was filed on behalf of Janus Henderson Group plc and the signature block shows it was signed by Kristin Mariani, Head of North America Compliance, on 5/15/2026.

Are all holdings held directly by Janus Henderson or by client accounts?

The filing explains the holdings are held in client Managed Portfolios for which affiliated Asset Managers exercise discretion; the Asset Managers disclaim rights to receive dividends or sale proceeds directly from those holdings.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 05/15/2026 - 11:23 AM EDT Learn about SEC filing dates

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 13)

OSI SYSTEMS, INC.

(Name of Issuer)

Common Stock

(Title of Class of Securities)

671044105

(CUSIP Number)

03/31/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

schemaVersion:

SCHEDULE 13G

CUSIP Number(s): 671044105

1

Names of Reporting Persons

JANUS HENDERSON GROUP PLC

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

JERSEY

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 772,314.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 772,314.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

772,314.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

4.7 %

12

Type of Reporting Person (See Instructions)

HC

SCHEDULE 13G

Item 1.
(a)	Name of issuer: OSI SYSTEMS, INC.
(b)	Address of issuer's principal executive offices: 12525 CADRON AVE HAWTHORNE, CA 90250
Item 2.
(a)	Name of person filing: Janus Henderson Group plc
(b)	Address or principal business office or, if none, residence: 201 Bishopsgate EC2M 3AE, United Kingdom
(c)	Citizenship: Y9
(d)	Title of class of securities: Common Stock
(e)	CUSIP No.: 671044105
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: Janus Henderson Group plc (JHG) is the ultimate parent of a number of SEC-registered investment advisers and foreign equivalents thereof, including but not limited to Janus Henderson Investors US LLC, Janus Henderson Investors UK Limited, Janus Henderson Investors Australia Institutional Funds Management Limited, Janus Henderson Investors Middle East Limited, Janus Henderson Investors (Jersey) Limited, Janus Henderson Investors (Japan) Limited, Janus Henderson Investors (Singapore) Limited, Kapstream Capital Pty Limited, Privacore Capital Advisors LLC, Tabula Investment Management Limited, and Victory Park Capital Advisors LLC (each, an Asset Manager and together, the Asset Managers). The Asset Managers generally exercise investment and/or voting discretion on behalf of their clients which include investment companies, other investment advisers, institutional separate accounts and retail separate accounts (collectively referred to herein as Managed Portfolios). As a result of their exercise of investment and/or voting discretion on behalf of the Managed Portfolios, the Asset Managers may be deemed to be the beneficial owner of 772,314 common stock of OSI Systems, Inc. However, the Asset Managers do not have the right to receive any dividends from, or the proceeds from the sale of, the securities held in the Managed Portfolios and disclaim any ownership associated with such rights.
(b)	Percent of class: 4.7 %
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: 0
	(ii) Shared power to vote or to direct the vote: 772314
	(iii) Sole power to dispose or to direct the disposition of: 0
	(iv) Shared power to dispose or to direct the disposition of: 772314
Item 5.	Ownership of 5 Percent or Less of a Class.
	Not Applicable
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required. The Managed Portfolios have the right to receive all dividends from, and the proceeds from the sale of, the securities held in their respective accounts. Of the Managed Portfolios, none own more than five percent of the common stock of OSI Systems, Inc.
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	If a parent holding company has filed this schedule, pursuant to Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary. Please refer to Exhibit 99.
Item 8.	Identification and Classification of Members of the Group.
	If a group has filed this schedule pursuant to §240.13d-1(b)(1)(ii)(J), so indicate under Item 3(j) and attach an exhibit stating the identity and Item 3 classification of each member of the group. If a group has filed this schedule pursuant to §240.13d-1(c) or §240.13d-1(d), attach an exhibit stating the identity of each member of the group. N/A
Item 9.	Notice of Dissolution of Group.
	Notice of dissolution of a group may be furnished as an exhibit stating the date of the dissolution and that all further filings with respect to transactions in the security reported on will be filed, if required, by members of the group, in their individual capacity. See Item 5. N/A

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

JANUS HENDERSON GROUP PLC

Signature:	Kristin Mariani
Name/Title:	Head of North America Compliance
Date:	5/15/2026

Exhibit Information

Exhibit 24: Power of Attorney Exhibit 99: Item 7