RA Capital Management, L.P., RA Capital Healthcare Fund, L.P., and managers Peter Kolchinsky and Rajeev Shah report beneficial ownership of up to 19,549,271 shares of Ovid Therapeutics common stock as of June 30, 2026, representing 9.99% of the class. The Fund directly holds 10,500,968 shares plus pre-funded warrants for 5,013,426 shares and Series B warrants for 5,357,000 shares. Warrant “Beneficial Ownership Blockers” prevent exercises that would increase ownership above 9.99% of outstanding shares, limiting exercisability to 19,549,271 shares in total. Voting and dispositive power over the Fund’s holdings are delegated to RA Capital, and the reporting parties disclaim beneficial ownership except for determining obligations under Section 13(d) of the Act.
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None.
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Key Figures
Beneficially owned shares:19,549,271 sharesOwnership percentage:9.99%Direct common shares:10,500,968 shares+4 more
7 metrics
Beneficially owned shares19,549,271 sharesAggregate beneficial ownership of Ovid common stock as of June 30, 2026
Ownership percentage9.99%Percent of Ovid common stock beneficially owned, limited by Beneficial Ownership Blockers
Direct common shares10,500,968 sharesOvid common stock directly held by RA Capital Healthcare Fund, L.P.
Pre-funded warrants5,013,426 sharesShares of Ovid common stock underlying pre-funded warrants held by the Fund
Series B warrants5,357,000 sharesShares of Ovid common stock underlying Series B Common Warrants held by the Fund
Shares outstanding baseline186,640,102 sharesOvid common shares outstanding as of May 8, 2026, per Form 10-Q
Shares issuable from warrants counted9,048,303 sharesOvid common shares issuable upon exercise of the warrants included in 9.99% computation
Key Terms
Beneficial Ownership Blockers, pre-funded warrants, Series B warrants, Section 13(d) of the Act, +1 more
5 terms
Beneficial Ownership Blockersregulatory
"Each of the Warrants contains a provision (the "Beneficial Ownership Blockers") which precludes exercise"
pre-funded warrantsfinancial
"pre-funded warrants (the "Pre-Funded Warrants") exercisable for up to 5,013,426 shares"
Pre-funded warrants are financial instruments that give investors the right to purchase a company's stock at a set price, but with most or all of the purchase price paid upfront. They function like a coupon or gift card for stock, allowing investors to buy shares later at a fixed price, which can be beneficial if they want to avoid future price increases. This makes them important for investors seeking flexibility and certainty in their investment plans.
Series B warrantsfinancial
"Series B warrants (the "Series B Common Warrants" and, together with the Pre-Funded Warrants, the "Warrants")"
Series B warrants are contracts issued alongside a company's Series B financing that give the holder the right to buy a set number of shares at a fixed price within a specified time. For investors, they matter because they can provide leveraged upside if the company grows, or they can dilute existing shareholders when exercised—like a coupon promising a future share at a known price that can add value or change ownership stakes.
Section 13(d) of the Actregulatory
"may be deemed a beneficial owner, for purposes of Section 13(d) of the Act"
investment adviserfinancial
"RA Capital serves as investment adviser for the Fund and may be deemed a beneficial owner"
An investment adviser is a person or firm that professionally manages money and gives recommendations about buying, selling, or holding investments. Like a financial coach or guide, they have a legal duty to act in a client's best financial interest, so their advice, fees and potential conflicts can directly affect returns and risk — making their role important for investors who want informed, accountable help with portfolios.
FAQ
What ownership stake in OVID does RA Capital report in this 13G/A?
RA Capital and related reporting persons report beneficial ownership of 19,549,271 shares of Ovid Therapeutics common stock, equal to 9.99% of the class as of June 30, 2026, including shares underlying specific warrants.
How is RA Capital’s OVID position composed between shares and warrants?
The Fund holds 10,500,968 common shares, pre-funded warrants exercisable for up to 5,013,426 shares, and Series B warrants exercisable for up to 5,357,000 shares, all counted toward the reported 19,549,271 share beneficial ownership cap.
What limits RA Capital’s ability to exercise its OVID warrants?
Both Ovid warrant series contain Beneficial Ownership Blockers that bar exercises if, after exercise, RA Capital and affiliates would own more than 9.99% of Ovid’s outstanding common stock, effectively capping exercisable shares at 19,549,271.
On what share count is RA Capital’s 9.99% OVID ownership based?
The 9.99% figure uses 186,640,102 shares of Ovid common stock outstanding as of May 8, 2026, plus 9,048,303 shares issuable upon exercise of the warrants, as referenced in Ovid’s Form 10-Q filed with the SEC.
Who has voting and dispositive power over RA Capital’s OVID shares?
The Fund has delegated sole voting and dispositive power over its Ovid holdings to RA Capital, which serves as investment adviser. RA Capital, Peter Kolchinsky, and Rajeev Shah all disclaim beneficial ownership beyond Section 13(d) reporting purposes.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 1)
OVID THERAPEUTICS INC.
(Name of Issuer)
Common Stock par value $0.001 per share
(Title of Class of Securities)
690469101
(CUSIP Number)
06/30/2026
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
schemaVersion:
SCHEDULE 13G
CUSIP Number(s):
690469101
1
Names of Reporting Persons
RA Capital Management, L.P.
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
19,549,271.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
19,549,271.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
19,549,271.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
9.9 %
12
Type of Reporting Person (See Instructions)
IA, PN
SCHEDULE 13G
CUSIP Number(s):
690469101
1
Names of Reporting Persons
Peter Kolchinsky
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED STATES
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
19,549,271.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
19,549,271.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
19,549,271.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
9.9 %
12
Type of Reporting Person (See Instructions)
HC, IN
SCHEDULE 13G
CUSIP Number(s):
690469101
1
Names of Reporting Persons
Rajeev Shah
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED STATES
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
19,549,271.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
19,549,271.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
19,549,271.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
9.9 %
12
Type of Reporting Person (See Instructions)
HC, IN
SCHEDULE 13G
CUSIP Number(s):
690469101
1
Names of Reporting Persons
RA Capital Healthcare Fund, L.P.
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
19,549,271.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
19,549,271.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
19,549,271.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
9.9 %
12
Type of Reporting Person (See Instructions)
PN
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
OVID THERAPEUTICS INC.
(b)
Address of issuer's principal executive offices:
441 Ninth Avenue, 14th Floor, New York, NY, 10001.
Item 2.
(a)
Name of person filing:
The names of the persons filing this report (collectively, the "Reporting Persons") are:
RA Capital Management, L.P. ("RA Capital")
Peter Kolchinsky ("Dr. Kolchinsky")
Rajeev Shah ("Mr. Shah")
RA Capital Healthcare Fund, L.P. (the "Fund")
The Reporting Persons expressly disclaim status as a "group" for purposes of this Schedule 13G/A.
(b)
Address or principal business office or, if none, residence:
The address of the principal business office of each of the Reporting Persons is:
c/o RA Capital Management, L.P., 200 Berkeley Street, 18th Floor, Boston MA 02116
(c)
Citizenship:
RA Capital and the Fund are Delaware limited partnerships.
Dr. Kolchinsky and Mr. Shah are United States citizens.
(d)
Title of class of securities:
Common Stock par value $0.001 per share
(e)
CUSIP No.:
690469101
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
Row 9 of each Reporting Person's cover page to this Schedule 13G/A sets forth the aggregate number of shares of common stock of the Issuer beneficially owned by such Reporting Person as of June 30, 2026 and is incorporated by reference.
The Fund directly holds (i) 10,500,968 shares of common stock, (ii) pre-funded warrants (the "Pre-Funded Warrants") exercisable for up to 5,013,426 shares of common stock, and (iii) Series B warrants (the "Series B Common Warrants" and, together with the Pre-Funded Warrants, the "Warrants") exercisable for up to 5,357,000 shares of common stock. Each of the Warrants contains a provision (the "Beneficial Ownership Blockers") which precludes exercise of the Warrants to the extent that, following exercise, the Fund, together with its affiliates and other attribution parties, would own more than 9.99% of the common stock outstanding. The Fund is currently prohibited from exercising the Warrants to the extent that such exercise would result in the Reporting Persons' beneficial ownership of more than 19,549,271 shares of common stock.
RA Capital Healthcare Fund GP, LLC is the general partner of the Fund. The general partner of RA Capital is RA Capital Management GP, LLC, of which Dr. Kolchinsky and Mr. Shah are the controlling persons. RA Capital serves as investment adviser for the Fund and may be deemed a beneficial owner, for purposes of Section 13(d) of the Act, of any securities of the Issuer held by the Fund. The Fund has delegated to RA Capital the sole power to vote and the sole power to dispose of all securities held in the Fund's portfolio, including the shares of the Issuer's common stock reported herein. Because the Fund has divested voting and investment power over the reported securities it holds and may not revoke that delegation on less than 61 days' notice, the Fund disclaims beneficial ownership of the securities it holds for purposes of Section 13(d) of the Act. As managers of RA Capital, Dr. Kolchinsky and Mr. Shah may be deemed beneficial owners, for purposes of Section 13(d) of the Act, of any securities of the Issuer beneficially owned by RA Capital. RA Capital, Dr. Kolchinsky, and Mr. Shah disclaim beneficial ownership of the securities reported in this Schedule 13G/A other than for the purpose of determining their obligations under Section 13(d) of the Act, and the filing of this Schedule 13G/A shall not be deemed an admission that either RA Capital, Dr. Kolchinsky, or Mr. Shah is the beneficial owner of such securities for any other purpose.
(b)
Percent of class:
Due to the Beneficial Ownership Blocker listed in the Warrants, each Reporting Person's beneficial ownership percentage was 9.99% as of June 30, 2026. Such percentage is based upon the sum of (i) 186,640,102 shares of common stock outstanding as of May 8, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission (the "SEC") on May 12, 2026, and (ii) 9,048,303 shares of common stock issuable upon the exercise of the Warrants. Due to field limitations of the EDGAR filing system, the percentages listed in row 11 of the Reporting Persons' cover pages have been rounded down to 9.9%.
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
Row 5 of each Reporting Person's cover page to this Schedule 13G/A sets forth the sole power to vote or to direct the vote of securities of the Issuer beneficially owned by such Reporting Person as of June 30, 2026 and is incorporated by reference.
(ii) Shared power to vote or to direct the vote:
Row 6 of each Reporting Person's cover page to this Schedule 13G/A sets forth the shared power to vote or to direct the vote of securities of the Issuer beneficially owned by such Reporting Person as of June 30, 2026 and is incorporated by reference.
(iii) Sole power to dispose or to direct the disposition of:
Row 7 of each Reporting Person's cover page to this Schedule 13G/A sets forth the sole power to dispose or to direct the disposition of securities of the Issuer beneficially owned by such Reporting Person as of June 30, 2026 and is incorporated by reference.
(iv) Shared power to dispose or to direct the disposition of:
Row 8 of each Reporting Person's cover page to this Schedule 13G/A sets forth the shared power to dispose or to direct the disposition of securities of the Issuer beneficially owned by such Reporting Person as of June 30, 2026 and is incorporated by reference.
Item 5.
Ownership of 5 Percent or Less of a Class.
Not Applicable
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
Not Applicable
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
Not Applicable
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
RA Capital Management, L.P.
Signature:
/s/ Peter Kolchinsky
Name/Title:
By Peter Kolchinsky, Authorized Signatory
Date:
08/14/2026
Peter Kolchinsky
Signature:
/s/ Peter Kolchinsky
Name/Title:
Peter Kolchinsky
Date:
08/14/2026
Rajeev Shah
Signature:
/s/ Rajeev Shah
Name/Title:
Rajeev Shah
Date:
08/14/2026
RA Capital Healthcare Fund, L.P.
Signature:
/s/ Peter Kolchinsky
Name/Title:
By RA Capital Healthcare Fund GP, LLC, its General Partner, By Peter Kolchinsky, Manager
Date:
08/14/2026
Exhibit Information
Exhibit 99.1 Joint Filing Agreement (incorporated by reference to Exhibit 99.1 to Schedule 13G filed on December 18, 2025)