RA Capital reports 750,000-share stake in Freenome

RA Capital Management, L.P., RA Capital Healthcare Fund, L.P., Dr. Peter Kolchinsky and Mr. Rajeev Shah report indirect ownership of 750,000 shares of Freenome, Inc. common stock, held directly by the Fund as of July 20, 2026.

Rhea-AI Filing Summary

RA Capital Management, L.P., RA Capital Healthcare Fund, L.P., Dr. Peter Kolchinsky and Mr. Rajeev Shah report indirect ownership of 750,000 shares of Freenome, Inc. common stock, held directly by the Fund as of July 20, 2026.

The Adviser acts as investment manager to the Fund, whose general partner is RA Capital Management GP, LLC. Each of the Adviser, the Adviser GP, the Fund, Dr. Kolchinsky and Mr. Shah disclaims beneficial ownership except to the extent of respective pecuniary interests.

Insider Trade Summary

1 transaction reported

Mixed 1 txn

Insider RA CAPITAL MANAGEMENT, L.P., RA Capital Healthcare Fund LP, Kolchinsky Peter, Shah Rajeev M.

Role Director | Director | Director | Director

Type	Security	Shares	Price	Value
holding	Common Stock F1, F2	--	--	--

Holdings After Transaction: Common Stock — 750,000 shares (Indirect, See footnotes)

Footnotes (2)

1. F1. RA Capital Management, L.P. (the "Adviser") is the investment manager for RA Capital Healthcare Fund, L.P. (the "Fund"). The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. Each of the Adviser, the Adviser GP, the Fund, Dr. Kolchinsky and Mr. Shah disclaims beneficial ownership of any of the reported securities, except to the extent of its or his respective pecuniary interest therein.
2. F2. Held directly by the Fund.

Key Figures

Indirectly held common stock: 750,000 shares

1 metrics

Indirectly held common stock 750,000 shares Freenome, Inc. common stock held by RA Capital Healthcare Fund, L.P. as of July 20, 2026

Key Terms

beneficial ownership, pecuniary interest, indirect ownership, investment manager

4 terms

beneficial ownership regulatory

"disclaims beneficial ownership of any of the reported securities, except to the extent"

Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.

pecuniary interest financial

"except to the extent of its or his respective pecuniary interest therein"

indirect ownership financial

"total_shares_following_transaction ... "ownership_type": "indirect""

investment manager financial

"RA Capital Management, L.P. (the "Adviser") is the investment manager for"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What stake in Freenome, Inc. does RA Capital report in this PCSC/FRNM Form 3?

RA Capital-related entities report indirect ownership of 750,000 shares of Freenome, Inc. common stock, held directly by RA Capital Healthcare Fund, L.P., with beneficial ownership disclaimed except for each party’s pecuniary interest.

How are the 750,000 Freenome (FRNM) shares held according to this Form 3 for PCSC?

The 750,000 common shares are held directly by RA Capital Healthcare Fund, L.P. Investment decisions are managed by RA Capital Management, L.P., which serves as the Fund’s investment manager through its general partner RA Capital Management GP, LLC.

Do RA Capital and its principals claim full beneficial ownership of Freenome (FRNM) shares?

No. The Adviser, its general partner, the Fund, Dr. Peter Kolchinsky and Mr. Rajeev Shah each disclaims beneficial ownership of the reported Freenome securities except to the extent of each party’s pecuniary interest in those shares.

What role does Dr. Peter Kolchinsky have in relation to Freenome, Inc. and RA Capital?

Dr. Peter Kolchinsky is a Managing Partner of the Adviser and serves on Freenome, Inc.’s board of directors. He is also a managing member of RA Capital Management GP, LLC and disclaims beneficial ownership except for his pecuniary interest.

Who are the reporting persons on this Freenome (FRNM) insider ownership report linked to PCSC?

The reporting persons are RA Capital Management, L.P., RA Capital Healthcare Fund, L.P., Dr. Peter Kolchinsky, and Mr. Rajeev Shah, all associated with management or control of the investment entities holding Freenome common stock.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 07/22/2026 - 05:27 PM Accepted by SEC EDGAR 07/22/2026 - 05:27 PM Learn about SEC filing dates

SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0104
Estimated average burden
hours per response:			0.5

1. Name and Address of Reporting Person^*

RA CAPITAL MANAGEMENT, L.P.

(Last) (First) (Middle)

200 BERKELEY STREET, 18TH FLOOR

(Street)

BOSTON MASSACHUSETTS 02116

(City) (State) (Zip)

UNITED STATES

(Country)

2. Date of Event Requiring Statement (Month/Day/Year)
07/20/2026

3. Issuer Name and Ticker or Trading Symbol
Freenome, Inc. [ FRNM ]

3a. Foreign Trading Symbol

5. If Amendment, Date of Original Filed (Month/Day/Year)

4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

6. Individual or Joint/Group Filing (Check Applicable Line)

	Form filed by One Reporting Person
X	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	750,000	I	See footnotes(1)(2)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

1. Name and Address of Reporting Person^*

RA CAPITAL MANAGEMENT, L.P.

(Last) (First) (Middle)

200 BERKELEY STREET, 18TH FLOOR

(Street)

BOSTON MASSACHUSETTS 02116

(City) (State) (Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

RA Capital Healthcare Fund LP

(Last) (First) (Middle)

C/O RA CAPITAL MANAGEMENT, L.P.

200 BERKELEY STREET, 18TH FLOOR

(Street)

BOSTON MASSACHUSETTS 02116

(City) (State) (Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

Kolchinsky Peter

(Last) (First) (Middle)

C/O RA CAPITAL MANAGEMENT, L.P.

200 BERKELEY STREET, 18TH FLOOR

(Street)

BOSTON MASSACHUSETTS 02116

(City) (State) (Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

Shah Rajeev M.

(Last) (First) (Middle)

C/O RA CAPITAL MANAGEMENT, L.P.

200 BERKELEY STREET, 18TH FLOOR

(Street)

BOSTON MASSACHUSETTS 02116

(City) (State) (Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

Explanation of Responses:

1. RA Capital Management, L.P. (the "Adviser") is the investment manager for RA Capital Healthcare Fund, L.P. (the "Fund"). The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. Each of the Adviser, the Adviser GP, the Fund, Dr. Kolchinsky and Mr. Shah disclaims beneficial ownership of any of the reported securities, except to the extent of its or his respective pecuniary interest therein.

2. Held directly by the Fund.

Remarks:

Dr. Peter Kolchinsky, a Managing Partner of the Adviser, serves on the Issuer's board of directors.

	/s/ Peter Kolchinsky, Manager of RA Capital Management, L.P.	07/22/2026
	/s/ Peter Kolchinsky, Manager of RA Capital Healthcare Fund GP, LLC, the General Partner of RA Capital Healthcare Fund, L.P.	07/22/2026
	/s/ Peter Kolchinsky, individually	07/22/2026
	/s/ Rajeev Shah, individually	07/22/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 3: SEC 1473 (03-26)