Freenome, Inc. (FRNM) holder Perceptive adds 5.5M shares at $10

Rhea-AI Filing Summary

Freenome, Inc. reported that Perceptive Life Sciences Master Fund Ltd. acquired 5,500,000 shares of Common Stock on July 20, 2026 at $10.00 per share, in a grant/award-type acquisition. Following this transaction, the Master Fund’s reported Common Stock holdings total 10,871,847 shares. The securities are directly held by the Master Fund; Perceptive Advisors LLC, as investment manager, and Joseph Edelman, as managing member of the Advisor, report indirect pecuniary interests and each disclaims beneficial ownership beyond that. The Rule 10b5-1 trading plan checkbox was not marked for this transaction.

Insider Trade Summary

Net Buyer: 5,500,000 shares

Net Buy 1 txn

Insider PERCEPTIVE ADVISORS LLC, EDELMAN JOSEPH, PERCEPTIVE LIFE SCIENCES MASTER FUND LTD

Role 10% Owner | 10% Owner | 10% Owner

Type	Security	Shares	Price	Value
Grant/Award	Common Stock F1	5,500,000	$10.00	$55.00M

Holdings After Transaction: Common Stock — 10,871,847 shares (Indirect, See Footnote)

Footnotes (1)

1. F1. The securities are directly held by Perceptive Life Sciences Master Fund Ltd. (the "Master Fund"). Perceptive Advisors LLC (the "Advisor") serves as the investment manager of the Master Fund. Joseph Edelman is the managing member of the Advisor. Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his or its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purpose.

Key Figures

Common Stock acquired: 5,500,000 shares Acquisition price per share: $10.00 Shares held after transaction: 10,871,847 shares +1 more

4 metrics

Common Stock acquired 5,500,000 shares Grant/award acquisition on July 20, 2026

Acquisition price per share $10.00 Price for Common Stock acquired on July 20, 2026

Shares held after transaction 10,871,847 shares Reported Common Stock holdings of the Master Fund following the acquisition

Acquisition transaction count 1 Single grant/award-type acquisition reported in this Form 4

Key Terms

beneficial ownership, indirect pecuniary interest, investment manager, Section 16 of the Securities Exchange Act of 1934

4 terms

beneficial ownership regulatory

"Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16..., beneficial ownership of such securities"

Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.

indirect pecuniary interest regulatory

"...except to the extent of his or its indirect pecuniary interest therein..."

investment manager financial

"Perceptive Advisors LLC (the "Advisor") serves as the investment manager of the Master Fund"

Section 16 of the Securities Exchange Act of 1934 regulatory

"Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership..."

A provision of federal securities law that requires company insiders—directors, officers and large shareholders—to publicly report their stock holdings and trades and to surrender any “short-swing” profits from purchases and sales within a six-month window. It acts like a rule that forces leaders to announce their trades and prevents quick buy-sell windfalls, giving investors transparency into insider activity and reducing opportunities for unfair gain.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Form 4 Insider Transactions: What Each Field Means →

Available on EDGAR 07/22/2026 - 09:08 PM Accepted by SEC EDGAR 07/22/2026 - 09:08 PM Learn about SEC filing dates

FAQ

What insider transaction was disclosed in the PCSC-related Form 4 for Freenome, Inc.?

The Form 4 reports that Perceptive Life Sciences Master Fund Ltd. acquired 5,500,000 shares of Freenome Common Stock at $10.00 per share on July 20, 2026, in a grant/award-type acquisition, increasing its reported holdings significantly.

How many Freenome shares are reported after the PCSC Form 4 transaction?

After the reported transaction, Perceptive Life Sciences Master Fund Ltd. holds 10,871,847 shares of Freenome Common Stock. This figure reflects the Master Fund’s position following the 5,500,000-share acquisition disclosed in the Form 4 filing.

Who actually holds the Freenome shares in the PCSC Form 4 filing?

The Common Stock is directly held by Perceptive Life Sciences Master Fund Ltd.. Perceptive Advisors LLC, as investment manager, and Joseph Edelman, as managing member, report only indirect pecuniary interests and disclaim beneficial ownership beyond those interests.

Was the Freenome (PCSC-related) Form 4 transaction under a Rule 10b5-1 plan?

No. The Rule 10b5-1 trading plan checkbox is not marked in this Form 4. This indicates the reported 5,500,000-share acquisition was not affirmatively identified as executed under a pre-arranged Rule 10b5-1 trading plan.

What price was paid for the Freenome shares in this PCSC Form 4 disclosure?

The reported acquisition price is $10.00 per share for the 5,500,000 Freenome Common Stock shares. This per-share price applies to the entire block acquired in the grant/award-type transaction dated July 20, 2026.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

PERCEPTIVE ADVISORS LLC

(Last) (First) (Middle)

51 ASTOR PLACE, 10TH FLOOR

(Street)

NEW YORK NEW YORK 10003

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
Freenome, Inc. [ FRNM ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
07/20/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

	Form filed by One Reporting Person
X	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	07/20/2026		A		5,500,000	A	$10	10,871,847	I	See Footnote(1)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

1. Name and Address of Reporting Person^*

PERCEPTIVE ADVISORS LLC

(Last) (First) (Middle)

51 ASTOR PLACE, 10TH FLOOR

(Street)

NEW YORK NEW YORK 10003

(City) (State) (Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

EDELMAN JOSEPH

(Last) (First) (Middle)

51 ASTOR PLACE, 10TH FLOOR

(Street)

NEW YORK NEW YORK 10003

(City) (State) (Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

PERCEPTIVE LIFE SCIENCES MASTER FUND LTD

(Last) (First) (Middle)

51 ASTOR PLACE, 10TH FLOOR

(Street)

NEW YORK NEW YORK 10003

(City) (State) (Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

Explanation of Responses:

1. The securities are directly held by Perceptive Life Sciences Master Fund Ltd. (the "Master Fund"). Perceptive Advisors LLC (the "Advisor") serves as the investment manager of the Master Fund. Joseph Edelman is the managing member of the Advisor. Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his or its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purpose.

	/s/ Joseph Edelman - for Perceptive Advisors LLC, By: Joseph Edelman, its managing member	07/22/2026
	/s/ Joseph Edelman - for Perceptive Life Sciences Master Fund Ltd., By: Perceptive Advisors LLC, its investment manager, By: Joseph Edelman, its managing member	07/22/2026
	/s/ Joseph Edelman	07/22/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)