Commodore Capital reports 0% PCSC (NASDAQ: PCSC) ownership in 13G/A

Rhea-AI Filing Summary

Perceptive Capital Solutions Corp received an amended Schedule 13G/A from Commodore Capital LP and Commodore Capital Master LP reporting that they beneficially own 0 Class A ordinary shares, representing 0.0% of the class as of 12/31/2025. The filers certify the securities were not acquired or held to change or influence control of the company.

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 1)

Perceptive Capital Solutions Corp

(Name of Issuer)

Class A Ordinary Shares, par value $0.0001 per share

(Title of Class of Securities)

G70077105

(CUSIP Number)

12/31/2025

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

SCHEDULE 13G

CUSIP No. G70077105

1

Names of Reporting Persons

Commodore Capital LP

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

0.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

0.0 %

12

Type of Reporting Person (See Instructions)

IA, PN

SCHEDULE 13G

CUSIP No. G70077105

1

Names of Reporting Persons

Commodore Capital Master LP

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

CAYMAN ISLANDS

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

0.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

0.0 %

12

Type of Reporting Person (See Instructions)

PN

SCHEDULE 13G

Item 1.
(a)	Name of issuer: Perceptive Capital Solutions Corp
(b)	Address of issuer's principal executive offices: 51 Astor Place, 10th Floor, New York, NEW YORK, 10003.
Item 2.
(a)	Name of person filing: Commodore Capital LP Commodore Capital Master LP Each a "Filer."
(b)	Address or principal business office or, if none, residence: The address for Commodore Capital LP is 444 Madison Avenue, Floor 35, New York, NY 10022.The address for Commodore Capital Master LP is c/o Maples Corporate Services Limited, Ugland House, South Church Street, PO Box 309, Grand Cayman KY1-1104, Cayman Islands.
(c)	Citizenship: See Item 4 of the cover page for each Filer.
(d)	Title of class of securities: Class A Ordinary Shares, par value $0.0001 per share
(e)	CUSIP No.: G70077105
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: See Item 9 of the cover page for each Filer.
(b)	Percent of class: See item 11 of the cover page for each Filer.
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: See item 5 of the cover page for each Filer.
	(ii) Shared power to vote or to direct the vote: See item 6 of the cover page for each Filer.
	(iii) Sole power to dispose or to direct the disposition of: See item 7 of the cover page for each Filer.
	(iv) Shared power to dispose or to direct the disposition of: See item 8 of the cover page for each Filer.
Item 5.	Ownership of 5 Percent or Less of a Class.
	Ownership of 5 percent or less of a class
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	Not Applicable
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Commodore Capital LP

Signature:	Michael Kramarz
Name/Title:	Managing Partner
Date:	02/17/2026

Commodore Capital Master LP

Signature:	Michael Kramarz
Name/Title:	Authorized Signatory
Date:	02/17/2026

FAQ

What does PCSC’s Schedule 13G/A filing by Commodore Capital report?

The Schedule 13G/A reports that Commodore Capital LP and Commodore Capital Master LP now hold 0 Class A ordinary shares of Perceptive Capital Solutions Corp, representing 0.0% of the class as of December 31, 2025, indicating they are no longer significant beneficial owners.

Who are the reporting persons in the PCSC Schedule 13G/A amendment?

The reporting persons are Commodore Capital LP, a Delaware entity, and Commodore Capital Master LP, organized in the Cayman Islands. Both are identified as filers regarding beneficial ownership of Perceptive Capital Solutions Corp’s Class A ordinary shares, with their respective business addresses listed in the filing.

How many Perceptive Capital Solutions Corp shares does Commodore Capital beneficially own?

Commodore Capital LP and Commodore Capital Master LP each report beneficial ownership of 0.00 Class A ordinary shares. This corresponds to 0.0% of Perceptive Capital Solutions Corp’s Class A ordinary share class, as disclosed in the ownership section of the Schedule 13G/A filing.

What percentage of PCSC’s Class A shares is reported in this Schedule 13G/A?

The filing states that the aggregate amount beneficially owned by each reporting person represents 0.0% of Perceptive Capital Solutions Corp’s Class A ordinary shares. This confirms that the filers’ ownership has fallen to 5 percent or less of the outstanding class.

What does the control-related certification in the PCSC Schedule 13G/A mean?

The certification states the securities referenced were not acquired and are not held to change or influence control of Perceptive Capital Solutions Corp. It also notes they are not held in connection with any control-related transaction, other than activities tied solely to a nomination under Rule 14a-11.

Who signed the Schedule 13G/A for Perceptive Capital Solutions Corp?

The filing is signed by Michael Kramarz. He signs once as Managing Partner and again as Authorized Signatory, each dated February 17, 2026, certifying to the truth, completeness, and correctness of the information contained in the Schedule 13G/A.