Perceptive Advisors (PCSC) discloses 10.1% Freenome stake via 10.9M shares

Rhea-AI Filing Summary

Perceptive Advisors LLC, together with Joseph Edelman and Perceptive Life Sciences Master Fund, Ltd., reports beneficial ownership of Freenome, Inc. Common Stock on a Schedule 13G. The Master Fund directly holds 10,871,847 shares of Common Stock, and each Reporting Person may be deemed to beneficially own these shares.

The ownership represents 10.1% of Freenome’s Common Stock, based on 107,446,814 shares outstanding as of July 20, 2026 as reported by the issuer. Each Reporting Person has 0 shares with sole voting or dispositive power and 10,871,847 shares with shared voting and shared dispositive power.

Key Figures

Shares beneficially owned: 10,871,847 shares Ownership percentage: 10.1% Shares outstanding: 107,446,814 shares +4 more

7 metrics

Shares beneficially owned 10,871,847 shares Common Stock directly held by Perceptive Life Sciences Master Fund, Ltd.

Ownership percentage 10.1% Percentage of Freenome Common Stock beneficially owned by each Reporting Person

Shares outstanding 107,446,814 shares Freenome Common Stock outstanding as of July 20, 2026, as reported to the Reporting Persons

Shared voting power 10,871,847 shares Shares over which each Reporting Person has shared power to vote or direct the vote

Shared dispositive power 10,871,847 shares Shares over which each Reporting Person has shared power to dispose or direct disposition

Sole voting power 0 shares Shares with sole voting power for each Reporting Person

Sole dispositive power 0 shares Shares with sole dispositive power for each Reporting Person

Key Terms

beneficially own, shared voting power, shared dispositive power, Schedule 13G, +1 more

5 terms

beneficially own financial

"may be deemed to beneficially own shares held by the Master Fund"

Beneficially own means having the economic rights and risks of a security—such as the right to receive dividends, sell the shares, or profit from price changes—whether or not your name appears on the official share register. Think of it like renting a car: you use it and reap the benefits even if the title lists someone else. Investors care because beneficial ownership determines who truly controls value, must be disclosed under securities rules, and can signal potential influence or trading activity that affects a stock’s price.

shared voting power financial

"Shared Voting Power 10,871,847.00"

Shared voting power occurs when two or more parties jointly have the right to vote or decide how a block of company shares is cast, like co-owners who must agree before moving a piece of furniture. Investors care because who controls voting rights affects board elections, major corporate decisions and takeover outcomes, and shared control can alter regulatory disclosures and the practical influence any holder has over a company’s direction and value.

shared dispositive power financial

"Shared Dispositive Power 10,871,847.00"

Schedule 13G regulatory

"reports beneficial ownership of Freenome, Inc. Common Stock on a Schedule 13G"

A Schedule 13G is a formal document that investors file with the government when they acquire a large ownership stake in a company, usually for investment purposes rather than control. It helps keep the public informed about who owns significant parts of a company's shares, which can influence how the company is managed and how investors make decisions. Filing this schedule is important for transparency and understanding the ownership landscape of publicly traded companies.

CUSIP Number financial

"CUSIP Number(s): 35661P100"

A CUSIP number is a nine-character code that uniquely identifies a specific U.S. or Canadian stock, bond, or other security, similar to a barcode or a social-security number for a financial instrument. It matters to investors because it removes confusion between similar securities, ensures trades and settlements are applied to the correct issue, and helps locate official documents and transaction records quickly.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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FAQ

What percentage of Freenome, Inc. (PCSC) does Perceptive Advisors report owning?

Perceptive Advisors, Joseph Edelman, and the Master Fund each report beneficial ownership of 10.1% of Freenome, Inc. Common Stock, based on 107,446,814 shares outstanding as of July 20, 2026.

How many Freenome, Inc. (PCSC) shares are directly held by Perceptive Life Sciences Master Fund, Ltd.?

Perceptive Life Sciences Master Fund, Ltd. directly holds 10,871,847 shares of Freenome, Inc. Common Stock. Perceptive Advisors, as investment manager, and Joseph Edelman, as managing member, may be deemed to beneficially own these shares.

What voting power does Perceptive Advisors have over Freenome, Inc. (PCSC) shares?

Perceptive Advisors has 0 Freenome shares with sole voting power and 10,871,847 shares with shared voting power, matching the Master Fund’s holdings reported on the Schedule 13G.

What is the total number of Freenome, Inc. (PCSC) shares outstanding used for the 13G calculation?

The reported ownership percentages are calculated using 107,446,814 shares of Freenome, Inc. Common Stock outstanding as of July 20, 2026, as provided to the reporting persons by the issuer.

Who are the reporting persons on the Freenome, Inc. (PCSC) Schedule 13G?

The reporting persons are Perceptive Advisors LLC, Joseph Edelman, and Perceptive Life Sciences Master Fund, Ltd., collectively referred to as the “Reporting Persons” with respect to Freenome’s Common Stock.

Do the reporting persons have sole or shared dispositive power over Freenome, Inc. (PCSC) shares?

Each reporting person has 0 shares with sole dispositive power and 10,871,847 shares with shared dispositive power over Freenome, Inc. Common Stock, corresponding to the Master Fund’s direct holdings.

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

Freenome, Inc.

(Name of Issuer)

Common Stock, par value $0.0001 per share

(Title of Class of Securities)

35661P100

(CUSIP Number)

07/20/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

schemaVersion:

SCHEDULE 13G

CUSIP Number(s): 35661P100

1

Names of Reporting Persons

Perceptive Advisors LLC

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 10,871,847.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 10,871,847.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

10,871,847.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

10.1 %

12

Type of Reporting Person (See Instructions)

IA

SCHEDULE 13G

CUSIP Number(s): 35661P100

1

Names of Reporting Persons

Joseph Edelman

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 10,871,847.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 10,871,847.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

10,871,847.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

10.1 %

12

Type of Reporting Person (See Instructions)

IN

SCHEDULE 13G

CUSIP Number(s): 35661P100

1

Names of Reporting Persons

Perceptive Life Sciences Master Fund, Ltd.

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

CAYMAN ISLANDS

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 10,871,847.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 10,871,847.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

10,871,847.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

10.1 %

12

Type of Reporting Person (See Instructions)

CO

SCHEDULE 13G

Item 1.
(a)	Name of issuer: Freenome, Inc.
(b)	Address of issuer's principal executive offices: Genesis Marina, 3300 Marina Blvd, Brisbane, California , 94005
Item 2.
(a)	Name of person filing: The names of the persons filing this report (collectively, the "Reporting Persons") with respect to the Common Stock, par value $0.0001 per share (the "Common Stock") of Freenome, Inc. (the "Issuer") are: (i) Perceptive Advisors LLC ("Perceptive Advisors") (ii) Joseph Edelman ("Mr. Edelman") (iii) Perceptive Life Sciences Master Fund, Ltd. (the "Master Fund")
(b)	Address or principal business office or, if none, residence: The address of the principal business office of each of the Reporting Persons is: 51 Astor Place, 10th Floor, New York, NY 10003
(c)	Citizenship: Perceptive Advisors is a Delaware limited liability company. Mr. Edelman is a United States citizen. The Master Fund is a Cayman Islands corporation.
(d)	Title of class of securities: Common Stock, par value $0.0001 per share
(e)	CUSIP Number(s): 35661P100
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: The information required by this item with respect to each Reporting Person is set forth in Rows 5 through 9 and 11 of the cover pages to this Schedule 13G. The ownership percentages reported are based on 107,446,814 shares of Common Stock oustsanding as of July 20, 2026, as reported to the Reporting Persons by the Issuer. The Master Fund directly holds 10,871,847 shares of Common Stock. Perceptive Advisors serves as the investment manager to the Master Fund and may be deemed to beneficially own shares held by the Master Fund. Mr. Edelman is the managing member of Perceptive Advisors and may be deemed to beneficially own the shares held by the Master Fund.
(b)	Percent of class: Perceptive Advisors: 10.1% Mr. Edelman: 10.1% Master Fund: 10.1%
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: Perceptive Advisors: 0 Mr. Edelman: 0 Master Fund: 0
	(ii) Shared power to vote or to direct the vote: Perceptive Advisors: 10,871,847 Mr. Edelman: 10,871,847 Master Fund: 10,871,847
	(iii) Sole power to dispose or to direct the disposition of: Perceptive Advisors: 0 Mr. Edelman: 0 Master Fund: 0
	(iv) Shared power to dispose or to direct the disposition of: Perceptive Advisors: 10,871,847 Mr. Edelman: 10,871,847 Master Fund: 10,871,847
Item 5.	Ownership of 5 Percent or Less of a Class.
	Not Applicable
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	Not Applicable
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Perceptive Advisors LLC

Signature:	/s/ Joseph Edelman
Name/Title:	Joseph Edelman, Managing Member
Date:	07/23/2026

Joseph Edelman

Signature:	/s/ Joseph Edelman
Name/Title:	Joseph Edelman
Date:	07/23/2026

Perceptive Life Sciences Master Fund, Ltd.

Signature:	/s/ Joseph Edelman
Name/Title:	Joseph Edelman, Managing Member
Date:	07/23/2026

Exhibit Information

Exhibit 99.1 - Joint Filing Agreement