Pharming preliminary Q3 2026 revenue rises 21%
PHAR's narrowed 2026 revenue range accompanies nine-month operating cash flow of US$24.7 million, versus US$44.0 million a year earlier.
Sentiment and the balance of points
Rhea-AI Sentiment reads the wording of the document, how positive or negative its language is on a 1 to 5 scale. The balance of points shown with the takes weighs what the document actually discloses, so the two can disagree, for example when a trial that missed its main goal is described in upbeat language.
Form Type
6-K
Rhea-AI Filing Summary
Pharming Group N.V. (PHAR) reported preliminary, unaudited third-quarter 2026 revenue of US$117.6 million, up 21% year over year and above market expectations. RUCONEST revenue rose 14% to US$93.8 million and Joenja revenue rose 58% to US$23.8 million. Operating profit increased 89% to US$29.9 million; net profit was US$22.4 million, versus US$7.5 million a year earlier. Pharming narrowed its 2026 total revenue guidance to US$380.0 million–US$390.0 million from US$375.0 million–US$395.0 million.
For the first nine months, revenue was US$280.2 million versus US$269.6 million, operating cash flow was US$24.7 million versus US$44.0 million, and net profit was US$18.9 million versus a US$2.8 million loss. Cash, restricted cash and marketable securities totaled US$190.9 million at September 30, 2026. Pharming reported positive Phase II topline data for leniolisib in genetically identifiable primary immunodeficiencies; CVID Phase II topline results are expected in November 2026. Shipments of newly approved U.S. Joenja doses for children aged 4 to 11 weighing at least 27 kg began in October, after quarter-end. The lower-dose pediatric application received Priority Review, with a PDUFA target action date of January 30, 2027.
3 points · 0 major0 major · 1 point
How this balance works
Rhea-AI gives every point it takes from this document a weight. Minor counts 1, Moderate 3 and Major 9, so one Major point outweighs several Minor ones. The bar adds up the weights on each side, and when neither side holds more than 65% of the total the balance reads Mixed.
It reads the document as published, with the same rules for every company, and it does not look at what the market expected or at how the stock traded, so a point can be objectively good on a day the stock falls.
Rhea-AI Sentiment measures something else, the tone of the wording.
Positive
- Moderate pointThird-quarter revenue increased 21% to US$117.6 million.
- Moderate pointThird-quarter operating profit increased 89% to US$29.9 million.
- Moderate pointNine-month net profit was US$18.9 million, versus a US$2.8 million loss.
Negative
- Moderate pointNine-month operating cash flow was US$24.7 million, versus US$44.0 million.
Filing Explained
Adjusted third-quarter operating profit was US$35.0 million after excluding a US$5.1 million inventory impairment; reported operating profit was US$29.9 million.
Pharming furnishes preliminary, unaudited results for the quarter ended
For the quarter, the company reports adjusted operating profit of
Key Figures
Total revenue: US$117.6 million
Operating profit: US$29.9 million
Net profit: US$22.4 million
+5 more
8 metrics
Total revenue
US$117.6 million
Third quarter 2026; US$97.3 million in third quarter 2025; up 21%.
Operating profit
US$29.9 million
Third quarter 2026; US$15.8 million in third quarter 2025; up 89%.
Net profit
US$22.4 million
Third quarter 2026; US$7.5 million in third quarter 2025.
Joenja revenue
US$23.8 million
Third quarter 2026; up 58% compared with third quarter 2025.
Net profit
US$18.9 million
First nine months of 2026; US$2.8 million loss in the first nine months of 2025.
Operating cash flow
US$24.7 million
First nine months of 2026; US$44.0 million in the first nine months of 2025.
Total revenue guidance
US$380.0 million–US$390.0 million
2026 guidance, narrowed from US$375.0 million–US$395.0 million.
Cash and cash equivalents, restricted cash and marketable securities
US$190.9 million
As of September 30, 2026.
Key Terms
activated PI3Kδ syndrome (APDS), common variable immunodeficiency (CVID), Prescription Drug User Fee Act (PDUFA) target action date, Expanded Access Program, +1 more
5 terms
activated PI3Kδ syndrome (APDS) medical
"diagnosed activated PI3Kδ syndrome (APDS) patients"
common variable immunodeficiency (CVID) medical
"common variable immunodeficiency (CVID)"
Common variable immunodeficiency (CVID) is a chronic immune disorder in which the body makes too few protective antibodies, leaving people prone to repeated infections and other immune problems; it typically requires ongoing medical care such as immunoglobulin replacement and monitoring. Investors should care because CVID creates a long-term market for diagnostics, therapies and supportive care—like a building that needs permanent security upgrades—so advances, approvals, or changes in treatment cost or reimbursement can meaningfully affect companies in diagnostics, biologics and specialty care.
Prescription Drug User Fee Act (PDUFA) target action date regulatory
"assigned a Prescription Drug User Fee Act (PDUFA) target action date"
Expanded Access Program medical
"leniol… Expanded Access Program (compassionate use)"
A program that allows patients with serious or life‑threatening conditions to receive an experimental drug or therapy before it is fully approved by regulators, when they cannot join clinical trials. Investors care because expanded access can change a treatment’s market perception, create early real‑world safety or demand signals, and affect regulatory timelines and potential revenue — like a pre‑order system that also reveals how the product performs outside controlled testing.
Adjusted Operating Profit financial
"Adjusted Operating Profit is a non-IFRS measure"
Adjusted operating profit is a measure of a company’s routine profit from its core business activities after removing one‑time events, unusual costs or non‑cash items so the result reflects ongoing operations. Think of it like judging a car’s normal fuel efficiency after ignoring a single visit to the body shop; investors use it to compare underlying profitability across periods or peers and to judge whether the business is sustainably earning money, but the specific exclusions can be subjective.
FAQ
AI-generated questions and answers. How Rhea-AI works. Not financial advice.
What were PHAR's third-quarter 2026 results?
Pharming reported third-quarter revenue of US$117.6 million, operating profit of US$29.9 million, and net profit of US$22.4 million. Revenue was up 21% and operating profit was up 89% compared with the third quarter of 2025.
What is Pharming Group's 2026 revenue guidance?
Pharming narrowed its 2026 total revenue guidance to US$380.0 million–US$390.0 million, from US$375.0 million–US$395.0 million.
What did PHAR report from the leniolisib Phase II study?
Pharming presented positive topline data from a Phase II study in genetically identifiable primary immunodeficiencies with immune dysregulation. The study enrolled 13 participants, 12 completed it, and all 12 who completed elected to enter the three-year extension study; mean spleen volume reduction was 26.4%.
When will Pharming report CVID Phase II results?
Pharming expects to report leniolisib Phase II results in CVID patients with immune dysregulation, with or without an identified genetic cause, in November 2026.
Who became Pharming's interim co-CEOs?
Leverne Marsh, Pharming's Chief Commercial Officer, and Kenneth Lynard, its Chief Financial Officer, were appointed interim co-CEOs after Fabrice Chouraqui stepped down as Chief Executive Officer and Executive Director with immediate effect on September 29, 2026.
AI-generated analysis. How Rhea-AI works. Not financial advice.
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 6-K
REPORT OF FOREIGN PRIVATE ISSUER
PURSUANT TO RULE 13a-16 OR 15d-16
UNDER THE SECURITIES EXCHANGE ACT OF 1934
For the Month of October 2026
Commission File Number: 001-39822
Pharming Group N.V.
(Exact Name of Registrant as Specified in Its Charter)
Darwinweg 24
2333 CR Leiden
The Netherlands
(Address of principal executive offices)
Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.
Form 20-F ☒ Form 40-F ☐
Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1): ☐
Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7): ☐
Furnished as Exhibit 99.1 to this Report on Form 6-K is a press release of Pharming Group N.V., dated October 27, 2026.
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EXHIBIT INDEX
| Exhibit No. | Description | |||||||
| 99.1 | Pharming Group reports third quarter 2026 financial results; strong revenue growth, Joenja APDS expansion and CVID topline data in November | |||||||
SIGNATURE
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.
Pharming Group N.V. | |||||||||||
By: | /s/ Kenneth Lynard | ||||||||||
Name: | Kenneth Lynard | ||||||||||
Title: | Interim Co-CEO & CFO | ||||||||||
Date: October 27, 2026
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For investor audiences and media only
Pharming Group reports third quarter 2026 financial results; strong revenue growth, Joenja APDS expansion and CVID topline data in November
•Third quarter 2026 total revenues increased by 21% to US$117.6 million, compared to third quarter 2025, exceeding market expectations
•RUCONEST® revenue increased by 14% to US$93.8 million, compared to third quarter 2025, reflecting demand stabilization and seasonal inventory increase
•Joenja® (leniolisib) revenue increased by 58% to US$23.8 million, compared to third quarter 2025, reflecting strong U.S. and international demand
•Tightened 2026 total revenue guidance to US$380 million - US$390 million from prior US$375 million - US$395 million
•Operating profit increased by 89% to US$29.9 million, compared to third quarter 2025
•Generated US$32.4 million in cash flow from operations in the quarter and US$24.7 million year to date, increasing cash position to US$190.9 million
•Strong progress on Joenja expansion including U.S. pediatric label and launches in Germany and Japan
•Announced positive Phase II topline data for leniolisib in genetic PIDs with immune dysregulation and Phase II topline data in broader CVID patient population expected in November 2026
•Pharming to host a conference call today at 13:30 CET (8:30 am EDT)
Leiden, the Netherlands, October 27, 2026: Pharming Group N.V. (Euronext Amsterdam: PHARM/Nasdaq: PHAR), a global biotechnology company focused on rare immune and genetic diseases, presents its preliminary (unaudited) financial report for the three months ended September 30, 2026.
Interim Co-Chief Executive Officer Kenneth Lynard commented: “This was a quarter of execution and delivery for Pharming. We set three near-term goals – stabilizing and returning RUCONEST to revenue growth, expanding Joenja (leniolisib)’s reach, and generating Phase II data for leniolisib beyond APDS. We made strong progress on all three in the third quarter, and momentum continues into the fourth quarter. RUCONEST quarterly revenue rose 14% year-over-year to $93.8 million, supported by stabilized U.S. demand with the strongest retention in the high-burden patient segment, and continued new patient and prescribers additions. Joenja revenue grew 58% to $23.8 million with launches in Germany and Japan, higher U.S. uptake, and approval in the U.S. of new doses for children aged 4 to 11 above 27 kg with shipments commencing after quarter end. That performance translated into 21% revenue growth exceeding market expectations, an 89% increase in operating profit, and strong operating cash flow, highlighting our flexibility to invest in our priorities while staying disciplined on capital allocation.
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Interim Co-Chief Executive Officer Leverne Marsh added: We are particularly encouraged by the recent positive Phase II results for leniolisib in genetically identifiable primary immunodeficiencies, which support the role of the PI3Kδ pathway in driving immune dysregulation beyond APDS. We look forward to reporting additional data in CVID in November. Together, results from both trials will inform the path toward a potential registrational study in the broader and larger CVID population. If supported by the data, this could represent a significant opportunity for leniolisib, building on the commercial capabilities we have established with Joenja to reach more patients and realize our long-term growth ambition.”
Third quarter highlights
Commercialized assets
RUCONEST marketed for the treatment of acute HAE attacks
RUCONEST revenue in the third quarter of 2026 was US$93.8 million, a 14% increase compared to the third quarter of 2025 and a 30% increase compared to the second quarter of 2026. Revenue for the first nine months of 2026 was US$224.5 million, a 3% decrease compared to the same period in 2025.
RUCONEST revenue in the current quarter compared to the third quarter of 2025 reflects stabilization and continued recovery of U.S. market demand, early seasonal increase in channel inventory at a single U.S. specialty pharmacy customer following significant drawdowns earlier in the year, and the completion of the planned withdrawal from non-U.S. markets.
The overwhelming majority of RUCONEST patients remain on therapy with the active patient base over 90% of year ago levels, with strongest retention in the high-burden patient segment. We continued to add new patients and prescribers, highlighting RUCONEST’s durable market position in high-burden HAE.
Joenja (leniolisib) marketed for the treatment of APDS
Joenja revenue increased to US$23.8 million in the third quarter of 2026, a 58% increase compared to the third quarter of 2025. Revenue for the first nine months of 2026 was US$55.7 million, a 45% increase compared to the same period in 2025.
Year-over-year revenue growth in the current quarter was driven by continued strong growth in the number of U.S. patients on paid therapy, significantly increased international demand - including from launches in Germany and Japan during the quarter and continued penetration in the U.K. - with temporary benefit from ordering patterns in other international markets.
The U.S. market contributed 67% of third quarter revenue, while international contributed 33%.
As of September 30, 2026, 136 patients were on paid therapy in the U.S., representing a 17% increase from the 116 patients at the end of the third quarter of 2025 and an increase of 4 patients during the quarter. Shipments of newly approved Joenja doses for children aged 4 to 11 years in the U.S. commenced in October, following the end of the quarter.
As of September 30, 2026, 75 patients were on paid therapy in international markets - 30 in launch markets and 45 on paid access programs in other international markets.
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APDS patient finding
As of September 30, 2026, we have identified 1,056 diagnosed activated PI3Kδ syndrome (APDS) patients of all ages globally, including 304 patients in the U.S. and 390 in core markets outside of the U.S.
Joenja (leniolisib) development
Leniolisib for APDS
As of September 30, 2026, there are 136 APDS patients in either a leniolisib Expanded Access Program (compassionate use) or an ongoing clinical study.
Pediatric label expansion
On September 11, 2026, we announced that the U.S. Food and Drug Administration (FDA) had approved our supplemental New Drug Application (sNDA) for 40 mg and 50 mg twice-daily dosing of Joenja as a treatment for children aged 4 to 11 years weighing at least 27 kg with APDS.
On July 30, 2026, we submitted a separate sNDA seeking approval of lower Joenja doses for pediatric APDS patients aged 4 to 11 years who weigh 13 kg to 27 kg. On September 28, 2026, we announced that the FDA had accepted this sNDA and granted the application Priority Review and assigned a Prescription Drug User Fee Act (PDUFA) target action date of January 30, 2027.
Japan
On August 13, 2026, we announced the commercial launch of Joenja (leniolisib) in Japan for adult and pediatric patients with APDS aged 4 years and older, following its inclusion on the Japan National Health Insurance (NHI) drug price list. With this launch, Japan became the first market where Joenja was commercially available for children aged 4 to 11.
Leniolisib for additional primary immunodeficiencies (PIDs)
Two Phase II clinical trials are evaluating leniolisib for additional primary immunodeficiencies (PIDs) with immune dysregulation, including genetically identifiable PIDs linked to altered PI3Kδ signaling and common variable immunodeficiency (CVID), which represent substantially larger patient populations than APDS. The PI3Kδ pathway is seen as a key driver of immune dysregulation in many PIDs, and we are working towards a single registrational Phase III trial in the broader CVID indication, incorporating patient populations from both studies.
On October 14, 2026, we presented positive topline data from our Phase II trial of leniolisib in genetically identifiable PIDs with immune dysregulation at the 22nd Biennial Meeting of the European Society for Immunodeficiencies (ESID). This is the first clinical data for leniolisib in broader PIDs beyond APDS, supporting the potential of targeted PI3Kδ inhibition to address immune dysregulation. The trial enrolled 13 participants, nine of whom also had a CVID diagnosis. All participants who completed the study elected to continue receiving treatment in a long-term extension study.
The presentation highlighted leniolisib’s favorable safety and tolerability profile, as well as clinical improvements across measures of immune dysregulation. Clinical results included improvements in lymphoproliferative disease, with mean 26.4% spleen volume reduction (SVR) including reductions in nearly all evaluable participants, and reductions in the size of index lesions. Positive
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trends in lung and liver disease markers were also particularly noteworthy. The safety observations were consistent with the known safety profile of leniolisib, with infections as the most common events observed in study subjects, and no new safety signals identified. Notably, all 12 participants who completed the study elected to enroll in the three-year extension study.
Pharming expects to report Phase II results for leniolisib in CVID patients with immune dysregulation, with or without an identified genetic cause, in November 2026.
The estimated prevalence rate is approximately 7.5 patients per million for genetically identifiable PIDs and approximately 39 patients per million for CVID with immune dysregulation, including overlap between the genetic PID and CVID populations, which are substantially larger than the approximately 1.5 patients per million for APDS.
Napazimone (KL1333) for mitochondrial DNA-driven primary mitochondrial disease
Napazimone (KL1333) is being evaluated in the pivotal FALCON clinical trial in adult patients with mtDNA-driven mitochondrial disease, and has the potential to become the first standard of care in this setting.
Over 50 clinical sites in the trial are actively recruiting, with significant expansion achieved in the U.S. We expect approximately 145 of the planned 180 subjects to be enrolled in FALCON by the end of 2026. We now expect enrollment to be completed in the first half of 2027. Topline results from the pivotal FALCON study are expected approximately one year after the completion of enrollment.
Organizational updates
On September 29, 2026, we announced that the Board of Directors and Fabrice Chouraqui had mutually agreed that Mr. Chouraqui would step down as Chief Executive Officer and Executive Director, with immediate effect. To ensure continuity of leadership, the Board of Directors appointed Mrs. Leverne Marsh, Chief Commercial Officer, and Mr. Kenneth Lynard, Chief Financial Officer, as Interim Co-CEOs.
Pharming’s strategy, pipeline and commitment to patients remain unchanged. Focus remains on executing the strategic priorities and advancing the next phase of growth.
Pharming’s strategy, pipeline and commitment to patients remain unchanged. Focus remains on executing the strategic priorities and advancing the next phase of growth.
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Financial Summary
| Consolidated Statement of Income | 3Q 2026 | 3Q 2025 | 9M 2026 | 9M 2025 | ||||||||||
| Amounts in US$m except per share data | ||||||||||||||
| Total Revenues | 117.6 | 97.3 | 280.2 | 269.6 | ||||||||||
| Cost of sales | (15.4) | (7.1) | (36.6) | (24.4) | ||||||||||
| Gross profit | 102.2 | 90.2 | 243.7 | 245.2 | ||||||||||
| Other income | 2.3 | 0.1 | 4.1 | 2.3 | ||||||||||
| Research and development | (29.6) | (23.4) | (87.4) | (68.2) | ||||||||||
| General and administrative | (15.6) | (17.0) | (45.7) | (59.9) | ||||||||||
| Marketing and sales | (29.5) | (34.1) | (88.3) | (99.7) | ||||||||||
| Other Operating Costs | (74.6) | (74.5) | (221.5) | (227.9) | ||||||||||
| Operating profit (loss) | 29.9 | 15.8 | 26.3 | 19.6 | ||||||||||
| Finance result (net) and share of result in associates | 1.4 | (3.1) | 3.2 | (11.6) | ||||||||||
| Profit (loss) before tax | 31.2 | 12.7 | 29.5 | 8.0 | ||||||||||
| Income tax credit (expense) | (8.8) | (5.2) | (10.7) | (10.8) | ||||||||||
| Profit (loss) for the period | 22.4 | 7.5 | 18.9 | (2.8) | ||||||||||
| Earnings per share | ||||||||||||||
| Basic, attributable to equity holders of the parent (US$) | 0.032 | 0.011 | 0.027 | (0.004) | ||||||||||
| Diluted, attributable to equity holders of the parent (US$) | 0.030 | 0.010 | 0.025 | (0.004) | ||||||||||
| Segment information - Revenues | 3Q 2026 | 3Q 2025 | 9M 2026 | 9M 2025 | ||||||||||
Amounts in US$m | ||||||||||||||
| Revenue - RUCONEST (US) | 94.0 | 81.1 | 224.2 | 227.4 | ||||||||||
| Revenue - RUCONEST (EU and RoW) | (0.1) | 1.1 | 0.3 | 3.9 | ||||||||||
| Total Revenues - RUCONEST | 93.8 | 82.2 | 224.5 | 231.2 | ||||||||||
| Revenue - Joenja (US) | 15.9 | 13.4 | 42.8 | 34.6 | ||||||||||
| Revenue - Joenja (EU and RoW) | 7.9 | 1.7 | 12.9 | 3.7 | ||||||||||
| Total Revenues - Joenja | 23.8 | 15.1 | 55.7 | 38.4 | ||||||||||
| Total Revenues - US | 109.8 | 94.5 | 267.0 | 262.0 | ||||||||||
| Total Revenues - EU and RoW | 7.7 | 2.7 | 13.2 | 7.6 | ||||||||||
| Total Revenues | 117.6 | 97.3 | 280.2 | 269.6 | ||||||||||
| Consolidated Balance Sheet | September 30, 2026 | December 31, 2025 | ||||||
| Amounts in US$m | ||||||||
| Cash and cash equivalents, restricted cash and marketable securities | 190.9 | 181.1 | ||||||
| Current assets | 322.4 | 299.5 | ||||||
| Total assets | 496.6 | 500.0 | ||||||
| Current liabilities | 100.0 | 115.8 | ||||||
| Shareholders' equity | 291.2 | 277.1 | ||||||
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Financial highlights
Third quarter 2026
For the third quarter of 2026, total revenues increased by US$20.3 million, or 21%, to US$117.6 million, compared to US$97.3 million in the third quarter of 2025. RUCONEST revenues amounted to US$93.8 million, a 14% increase compared to the third quarter of 2025. This increase in RUCONEST revenues was primarily driven by a volume increase in the U.S. Joenja revenues amounted to US$23.8 million in the third quarter of 2026, a 58% increase compared to the third quarter of 2025. This increase in Joenja revenues was primarily driven by an increase in volume.
Gross profit increased by US$12.0 million or 13%, to US$102.2 million, compared to US$90.2 million in the third quarter of 2025, mainly due to the increase in revenues and partially offset by manufacturing-related impairments of inventory (US$5.1 million).
The operating profit increased 89% and amounted to US$29.9 million compared to US$15.8 million in the third quarter of 2025. Excluding US$5.1 million in one-time manufacturing-related impairments of inventory, adjusted operating profit1 in the third quarter 2026 amounted to US$35.0 million. Excluding US$0.2 million of non-recurring Abliva acquisition-related expenses, adjusted operating profit in the third quarter 2025 amounted to US$16.0 million. The improved operating result was primarily driven by an increase in revenues and other income from government grants supporting research and development activities.
The finance result (net) and share of result in associates amounted to a gain of US$1.4 million compared to a loss of US$3.1 million in the third quarter of 2025. This improvement was mainly driven by favorable EUR/USD exchange rate movements, resulting in a foreign currency gain of US$2.6 million in 2026, compared to a loss of US$0.4 million in the third quarter of 2025.
The Company had a net profit of US$22.4 million, compared to a net profit of US$7.5 million in the third quarter of 2025. This increase was primarily driven by higher revenues and a favorable change in the net finance result.
Cash generated from operations amounted to US$32.4 million, broadly in line with US$32.0 million in the third quarter of 2025. Cash and cash equivalents, restricted cash and marketable securities increased by US$31.4 million from US$159.5 million at the end of the second quarter of 2026 to US$190.9 million at the end of the third quarter of 2026. This increase was primarily driven by net profit, partially offset by unfavorable working capital movements, including an increase in trade and other receivables.
Nine months 2026
Total revenues increased 4% during the first nine months of 2026 to US$280.2 million, compared to US$269.6 million during the first nine months of 2025. Total RUCONEST revenues were 3% lower at US$224.5 million, compared to revenues of US$231.2 million for the first nine months of 2025. The decrease in RUCONEST revenues was primarily driven by a decrease in volume. Joenja revenues amounted to US$55.7 million in the first nine months of 2026, a 45% increase compared to the first nine months of 2025. This increase in Joenja revenues was primarily driven by an increase in volume.
1 Adjusted Operating Profit is a non-IFRS measure used by management to assess underlying operating performance and provides additional insight into the Company's core operating profitability. It excludes certain non-core items.
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Gross profit decreased by US$1.5 million, or 1%, to US$243.7 million, compared to US$245.2 million in the first nine months of 2025, mainly due to manufacturing-related impairments of inventory (US$10.0 million) partially offset by the increase in revenues.
The operating profit amounted to US$26.3 million compared to an operating profit of US$19.6 million in the first nine months of 2025. Excluding US$10.0 million in one-time manufacturing-related impairments of inventory and US$1.7 million in expenses associated with the closure of the production-support site in Évry, France, adjusted operating profit in the first nine months of 2026 amounted to US$38.0 million. Excluding US$10.1 million of non-recurring Abliva acquisition-related expenses, adjusted operating profit in the first nine months of 2025 amounted to US$29.7 million. The improved operating result was primarily driven by an increase in revenues and lower operating expenses, partially offset by manufacturing-related impairments of inventories in 2026.
The finance result (net) and share of result in associates amounted to a gain of US$3.2 million compared to a loss of US$11.6 million in the first nine months of 2025. This improvement was mainly driven by favorable EUR/USD exchange rate movements, resulting in a foreign currency gain of US$7.9 million in the first nine months of 2026, compared to a loss of US$5.0 million in the first nine months of 2025.
The Company had a net profit of US$18.9 million, compared to a net loss of US$2.8 million in the first nine months of 2025. This increase was primarily driven by higher revenues, lower operating expenses and a favorable change in the net finance result.
Cash generated from operations amounted to US$24.7 million, compared to US$44.0 million in the first nine months of 2025. Cash and cash equivalents, restricted cash and marketable securities increased by US$9.8 million from US$181.1 million at the end of 2025 to US$190.9 million at the end of the third quarter of 2026. This increase was primarily driven by net profit, partially offset by US$12.3 million settlement of the lease liability following the early termination of the DSP facility lease at Pivot Park in Oss, the Netherlands, in the first quarter of 2026.
Outlook/Summary
For 2026, the Company anticipates:
•Total revenues between US$380.0 million and US$390.0 million (1% to 4% growth).
•Total operating expenses between US$310.0 million and US$315.0 million (0% to 1% growth), including approximately US$35 million incremental R&D investment to advance the pipeline and US$9 million structural G&A cost reductions based on the plan announced in October 2025.
•RUCONEST revenue stabilization and return to growth during second half of 2026, and significant and accelerating annual Joenja U.S. and ex-U.S. growth.
•Commercial launches for leniolisib for APDS patients 12 years of age or older and for pediatrics in key global markets.
•Top-line data readouts for the two ongoing leniolisib Phase II clinical trials in PIDs with immune dysregulation, including CVID, to expand the asset’s addressable patient population.
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•Continued progress in enrollment of the pivotal FALCON clinical study for napazimone (KL1333) in mitochondrial DNA-driven primary mitochondrial diseases, with completion of enrollment by the first half of 2027.
•Enhancing capital efficiency to drive growth and build a leading global rare disease company.
•Continued focus on potential acquisitions and in-licensing of clinical stage opportunities in rare diseases. Financing, if required, would come via a combination of our strong balance sheet and access to capital markets.
No further specific financial guidance for 2026 is provided.
Trademarks
Joenja® and RUCONEST® are registered trademarks owned by or licensed to Pharming Group N.V. or its affiliates.
Additional information
Presentation
The conference call presentation is available on the Pharming.com website from 07:30 CET today.
Conference Call
The conference call will begin at 13:30 CET/08:30 EDT on Tuesday, October 27. A transcript will be made available on the Pharming.com website in the days following the call.
Please note, the Company will only take questions from dial-in attendees.
Webcast Link:
https://edge.media-server.com/mmc/p/nnjperkk
Conference call dial-in details:
https://register-conf.media-server.com/register/BI6feabfc862ab4ba1bc7e6386d00414a3
Additional information on how to register for the conference call/webcast can be found on the Pharming.com website.
For further public information, contact:
Pharming
Michael Levitan, VP Investor Relations & Capital Markets
T: +1 (908) 705 1696
E: investor@pharming.com
Saskia Mehring, Head of Corporate Communications
T: +31 6 28 32 60 41
E: media.relations@pharming.com
Media Relations
Julia Deutsch (Lyra Strategic Advisory on behalf of Pharming)
Julia Deutsch (Lyra Strategic Advisory on behalf of Pharming)
E: JDeutsch@lyraadvisory.com
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Netherlands: Leon Melens (LifeSpring Life Sciences Communication on behalf of Pharming)
T: +31 6 53 81 64 27
About Pharming Group N.V.
Pharming Group N.V. (Euronext Amsterdam: PHARM/Nasdaq: PHAR) is a global biotechnology company that develops and commercializes innovative medicines for people living with rare immune and genetic diseases.
Pharming Group N.V. (Euronext Amsterdam: PHARM/Nasdaq: PHAR) is a global biotechnology company that develops and commercializes innovative medicines for people living with rare immune and genetic diseases.
We combine specialized scientific, medical, regulatory and commercial expertise to advance a focused portfolio of approved medicines and development programs that address significant unmet medical needs. Guided by insights from patients and the wider rare disease community, we are dedicated to delivering innovative therapies for some of the most challenging rare diseases.
Pharming is headquartered in Leiden, the Netherlands, with operations in the United States and Europe.
For more information, visit www.pharming.com and find us on LinkedIn.
Auditor’s involvement
The Condensed Consolidated Interim Financial Statements have not been audited by the Company’s statutory auditor.
The Condensed Consolidated Interim Financial Statements have not been audited by the Company’s statutory auditor.
Forward-looking Statements
This press release may contain forward-looking statements. Forward-looking statements are statements of future expectations that are based on management’s current expectations and assumptions and involve known and unknown risks and uncertainties that could cause actual results, performance, or events to differ materially from those expressed or implied in these statements. These forward-looking statements are identified by their use of terms and phrases such as “aim”, “ambition”, “anticipate”, “believe”, “could”, “estimate”, “expect”, “goals”, “intend”, “may”, “milestones”, “objectives”, “outlook”, “plan”, “probably”, “project”, “risks”, “schedule”, “see”, “should”, “target”, “will” and similar terms and phrases. Examples of forward-looking statements may include statements with respect to timing and progress of Pharming's preclinical studies and clinical trials of its product candidates, Pharming's clinical and commercial prospects, and Pharming's expectations regarding its projected working capital requirements and cash resources, which statements are subject to a number of risks, uncertainties and assumptions, including, but not limited to the scope, progress and expansion of Pharming's clinical trials and ramifications for the cost thereof; and clinical, scientific, regulatory, commercial, competitive and technical developments. In light of these risks and uncertainties, and other risks and uncertainties that are described in Pharming's 2025 Annual Report and the Annual Report on Form 20-F for the year ended December 31, 2025, filed with the U.S. Securities and Exchange Commission, the events and circumstances discussed in such forward-looking statements may not occur, and Pharming's actual results could differ materially and adversely from those anticipated or implied thereby. All forward-looking statements contained in this press release are expressly qualified in their entirety by the cautionary statements contained or referred to in this section. Readers should not place undue reliance on forward-looking statements. Any forward-looking statements speak only as of the date of this press release and are based on information available to Pharming as of
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the date of this release. Pharming does not undertake any obligation to publicly update or revise any forward-looking statement as a result of new information, future events or other information.
Inside Information
This press release relates to the disclosure of information that qualifies, or may have qualified, as inside information within the meaning of Article 7(1) of the EU Market Abuse Regulation.
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Pharming Group N.V.
Condensed Consolidated Interim Financial Statements in US Dollars (unaudited)
For the period ended September 30, 2026
•Condensed consolidated interim statement of income
•Condensed consolidated interim statement of comprehensive income
•Condensed consolidated interim balance sheet
•Condensed consolidated interim statement of changes in equity
•Condensed consolidated interim statement of cash flows
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| CONDENSED CONSOLIDATED INTERIM STATEMENT OF INCOME | ||||||||
| For the period ended September 30 | ||||||||
| Amounts in US$ ‘000 | 9M 2026 | 9M 2025 | ||||||
| Revenues | 280,217 | 269,602 | ||||||
| Costs of sales | (36,553) | (24,366) | ||||||
| Gross profit | 243,664 | 245,236 | ||||||
| Other income | 4,097 | 2,303 | ||||||
| Research and development | (87,389) | (68,221) | ||||||
| General and administrative | (45,738) | (59,945) | ||||||
| Marketing and sales | (88,345) | (99,746) | ||||||
| Other Operating Costs | (221,472) | (227,911) | ||||||
| Operating profit (loss) | 26,289 | 19,628 | ||||||
| Fair value gain (loss) on revaluation | — | — | ||||||
| Other finance income | 11,152 | 1,748 | ||||||
| Other finance expenses | (8,144) | (13,048) | ||||||
| Finance result, net | 3,008 | (11,300) | ||||||
| Share of net profits (loss) in associates using the equity method | 233 | (279) | ||||||
| Profit (loss) before tax | 29,530 | 8,049 | ||||||
| Income tax credit (expense) | (10,677) | (10,838) | ||||||
| Profit (loss) for the period | 18,853 | (2,790) | ||||||
| Attributable to: | ||||||||
| Equity holders of the parent | 18,853 | (2,477) | ||||||
| Non-controlling interests | — | (313) | ||||||
| Earnings per share | ||||||||
| Basic, attributable to equity holders of the parent (US$) | 0.027 | (0.004) | ||||||
| Diluted, attributable to equity holders of the parent (US$) | 0.025 | (0.004) | ||||||
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| CONDENSED CONSOLIDATED INTERIM STATEMENT OF COMPREHENSIVE INCOME | ||||||||
| For the period ended September 30 | ||||||||
| Amounts in US$ ‘000 | 9M 2026 | 9M 2025 | ||||||
| Profit (loss) for the period | 18,853 | (2,790) | ||||||
| Currency translation differences | (11,258) | 26,092 | ||||||
| Items that may be subsequently reclassified to profit or loss | (11,258) | 26,092 | ||||||
| Fair value remeasurement investments | — | — | ||||||
| Items that shall not be subsequently reclassified to profit or loss | — | — | ||||||
| Other comprehensive income (loss), net of tax | (11,258) | 26,092 | ||||||
| Total comprehensive income (loss) for the period | 7,595 | 23,303 | ||||||
| Attributable to: | ||||||||
Equity holders of the parent | 7,595 | 23,616 | ||||||
| Non-controlling interests | — | (313) | ||||||
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| CONDENSED CONSOLIDATED INTERIM BALANCE SHEET | ||||||||
| Amounts in US$ ‘000 | September 30, 2026 | December 31, 2025 | ||||||
| Non-current assets | ||||||||
| Intangible assets | 125,667 | 135,538 | ||||||
| Property, plant and equipment | 6,165 | 7,233 | ||||||
| Right-of-use assets | 13,335 | 16,738 | ||||||
| Long-term prepayments | 91 | 94 | ||||||
| Deferred tax assets | 19,051 | 31,017 | ||||||
| Investment accounted for using the equity method | 2,109 | 1,944 | ||||||
| Investment in debt instruments designated as at FVTPL | 6,485 | 6,703 | ||||||
| Restricted cash | 1,355 | 1,227 | ||||||
| Total non-current assets | 174,258 | 200,495 | ||||||
| Current assets | ||||||||
| Inventories | 57,988 | 64,902 | ||||||
| Trade and other receivables | 74,831 | 54,704 | ||||||
| Restricted cash | — | 761 | ||||||
| Marketable securities | — | 33,796 | ||||||
| Cash and cash equivalents | 189,560 | 145,305 | ||||||
| Total current assets | 322,379 | 299,469 | ||||||
| Total assets | 496,637 | 499,963 | ||||||
| Equity | ||||||||
| Share capital | 8,086 | 8,009 | ||||||
| Share premium | 520,912 | 513,257 | ||||||
| Other reserves | 17,518 | 28,819 | ||||||
| Accumulated deficit | (255,277) | (272,983) | ||||||
| Shareholders’ equity | 291,239 | 277,102 | ||||||
| Non-current liabilities | ||||||||
| Convertible bonds | 94,344 | 92,719 | ||||||
| Lease liabilities | 11,102 | 14,351 | ||||||
| Total non-current liabilities | 105,446 | 107,070 | ||||||
| Current liabilities | ||||||||
| Convertible bonds | 5,584 | 5,336 | ||||||
| Provisions | 816 | 1,187 | ||||||
| Trade and other payables | 90,069 | 105,899 | ||||||
| Lease liabilities | 3,483 | 3,369 | ||||||
| Total current liabilities | 99,952 | 115,791 | ||||||
| Total equity and liabilities | 496,637 | 499,963 | ||||||
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| CONDENSED CONSOLIDATED INTERIM STATEMENT OF CHANGES IN EQUITY | |||||||||||||||||||||||
| For the period ended September 30 | |||||||||||||||||||||||
| Attributable to owners of the parent | |||||||||||||||||||||||
| Amounts in US$ ‘000 | Share capital | Share premium | Other reserves | Accumulated deficit | Total | Non-controlling interests | Total equity | ||||||||||||||||
| Balance at January 1, 2025 | 7,769 | 488,990 | (209) | (275,489) | 221,061 | — | 221,061 | ||||||||||||||||
| Profit (loss) for the period | — | — | — | (2,477) | (2,477) | (313) | (2,790) | ||||||||||||||||
| Reserves | — | — | — | — | — | — | — | ||||||||||||||||
| Other comprehensive income (loss) for the period | — | — | 26,092 | — | 26,092 | — | 26,092 | ||||||||||||||||
| Total comprehensive income (loss) for the period | — | — | 26,092 | (2,477) | 23,616 | (313) | 23,303 | ||||||||||||||||
| Other reserves | — | — | (32) | 32 | — | — | — | ||||||||||||||||
| Income tax benefit from excess tax deductions related to share-based payments | — | — | — | 807 | 807 | — | 807 | ||||||||||||||||
| Share-based compensation | — | — | — | 9,256 | 9,256 | — | 9,256 | ||||||||||||||||
| Options exercised / LTIP shares issued | 184 | 18,727 | — | (8,320) | 10,592 | — | 10,592 | ||||||||||||||||
| Acquisition of a subsidiary | — | — | — | — | — | 7,741 | 7,741 | ||||||||||||||||
| Acquisition of non-controlling interests | — | — | — | (687) | (687) | (7,428) | (8,115) | ||||||||||||||||
| Total transactions with owners, recognized directly in equity | 184 | 18,727 | (32) | 1,087 | 19,967 | 313 | 20,280 | ||||||||||||||||
| Balance at September 30, 2025 | 7,953 | 507,717 | 25,852 | (276,878) | 264,644 | — | 264,644 | ||||||||||||||||
| Balance at January 1, 2026 | 8,009 | 513,257 | 28,819 | (272,983) | 277,102 | — | 277,102 | ||||||||||||||||
| Profit (loss) for the period | — | — | — | 18,853 | 18,853 | — | 18,853 | ||||||||||||||||
| Reserves | — | — | — | — | — | — | — | ||||||||||||||||
| Other comprehensive income (loss) for the period | — | — | (11,258) | — | (11,258) | — | (11,258) | ||||||||||||||||
| Total comprehensive income (loss) for the period | — | — | (11,258) | 18,853 | 7,595 | — | 7,595 | ||||||||||||||||
| Other reserves | — | — | (43) | 34 | (9) | — | (9) | ||||||||||||||||
| Income tax benefit from excess tax deductions related to share-based payments | — | — | — | (629) | (629) | — | (629) | ||||||||||||||||
| Share-based compensation | — | — | — | 8,353 | 8,353 | — | 8,353 | ||||||||||||||||
| Options exercised / LTIP shares issued | 77 | 7,655 | — | (8,905) | (1,173) | — | (1,173) | ||||||||||||||||
| Total transactions with owners, recognized directly in equity | 77 | 7,655 | (43) | (1,147) | 6,542 | — | 6,542 | ||||||||||||||||
| Balance at September 30, 2026 | 8,086 | 520,912 | 17,518 | (255,277) | 291,239 | — | 291,239 | ||||||||||||||||
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| CONDENSED CONSOLIDATED INTERIM STATEMENT OF CASH FLOWS | ||||||||
| For the period ended September 30 | ||||||||
| Amounts in $’000 | 9M 2026 | 9M 2025 | ||||||
| Profit (loss) before tax | 29,530 | 8,049 | ||||||
| Adjustments to reconcile net profit (loss) to net cash used in operating activities: | ||||||||
| Depreciation, amortization, impairment of non-current assets | 8,745 | 8,010 | ||||||
| Equity settled share based payments | 8,353 | 9,256 | ||||||
| Loss (gain) on disposal of leases | (2) | (9) | ||||||
| Impairments of inventories¹ | 11,777 | 2,183 | ||||||
| Other finance income | (11,152) | (1,748) | ||||||
| Other finance expenses | 8,088 | 12,837 | ||||||
| Share of net result in associates using the equity method | (233) | 279 | ||||||
| Operating cash flows before changes in working capital | 55,106 | 38,857 | ||||||
| Changes in working capital: | ||||||||
| Inventories¹ | (5,372) | (5,686) | ||||||
| Provisions | (371) | — | ||||||
| Trade and other receivables | (14,801) | 11,453 | ||||||
| Payables and other current liabilities | (4,797) | 4,138 | ||||||
| Restricted cash | 569 | (1,018) | ||||||
| Total changes in working capital | (24,772) | 8,887 | ||||||
| Interest received | 2,991 | 1,723 | ||||||
| Income taxes received (paid) | (8,660) | (5,466) | ||||||
| Net cash flows generated from (used in) operating activities | 24,665 | 44,001 | ||||||
| Capital expenditure for property, plant and equipment | (601) | (480) | ||||||
| Investment intangible assets | — | (6) | ||||||
| Investment in associates using the equity method | — | (731) | ||||||
| Purchases of marketable securities | (102,646) | — | ||||||
| Proceeds from sale of marketable securities | 18,124 | 84,990 | ||||||
| Acquisition of a subsidiary, net of cash acquired | — | (57,476) | ||||||
| Net cash flows generated from (used in) investing activities | (85,123) | 26,297 | ||||||
| Payment of lease liabilities | (14,803) | (2,877) | ||||||
| Interests on lease liabilities | (349) | (848) | ||||||
| Interests on convertible bonds | (2,614) | (2,506) | ||||||
| Settlement of share based compensation awards | 5,703 | 14,564 | ||||||
| Acquisition of non-controlling interests | — | (7,876) | ||||||
| Net cash flows generated from (used in) financing activities | (12,063) | 457 | ||||||
| Increase (decrease) of cash | (72,521) | 70,755 | ||||||
| Exchange rate effects | (1,020) | 6,672 | ||||||
| Effect of reclassification of money market funds to cash and cash equivalents2 | 117,796 | — | ||||||
| Cash and cash equivalents at the beginning of the period | 145,305 | 54,944 | ||||||
| Total cash and cash equivalents at September 30 | 189,560 | 132,370 | ||||||
1 Comparative presentation updated for consistency.
2 Money market funds are classified as cash equivalents from April 1, 2026
2 Money market funds are classified as cash equivalents from April 1, 2026
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