Pharvaris exec sells 20K shares at $38.27

Rhea-AI Filing Summary

Pharvaris N.V. (PHVS) reported an insider transaction by Anne Lesage, Chief Early Development. On September 17, 2026, an entity she controls, GrayMatters Consulting B.V., sold 20,000 shares of common stock in open-market or private transactions at a weighted average price of $38.27 per share, with individual prices ranging from $38.04 to $38.65, in connection with a cashless stock option exercise. Following these transactions, Lesage is reported as holding 73,969 shares indirectly through GrayMatters Consulting B.V. and 56,450 shares directly, and no Rule 10b5‑1 trading plan is indicated.

Insider Trade Summary

Net Seller: 20,000 shares

Net Sell 2 txns

Insider Lesage Anne

Role Chief Early Development

Sold 20,000 shs ($765K)

Type	Security	Shares	Price	Value
Sale	Common Stock F1, F2	20,000	$38.2733	$765K
holding	Common Stock	--	--	--

Holdings After Transaction: Common Stock — 73,969 shares (Indirect, By GrayMatters Consulting BVBA); Common Stock — 56,450 shares (Direct)

Footnotes (2)

1. F1. The reported price represents a weighted average sale price for shares sold in multiple transactions on the reported date. The shares were sold in connection with the exercise of stock options in a cashless exercise transaction. The sales prices for the transactions ranged from $38.04 to $38.65. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.
2. F2. GrayMatters Consulting B.V., an entity controlled by Dr. Lesage

Key Figures

Shares sold: 20,000 shares Weighted average sale price: $38.27 per share Sale price range: $38.04–$38.65 per share +2 more

5 metrics

Shares sold 20,000 shares Common stock sold on September 17, 2026 by entity controlled by Anne Lesage

Weighted average sale price $38.27 per share Weighted average for multiple sale transactions on September 17, 2026

Sale price range $38.04–$38.65 per share Range of prices for the multiple sale transactions on September 17, 2026

Indirect holdings after transaction 73,969 shares Common stock held indirectly by GrayMatters Consulting B.V. after the sale

Direct holdings after transaction 56,450 shares Common stock held directly by Anne Lesage after the reported date

Key Terms

cashless exercise, weighted average sale price, indirect ownership

3 terms

cashless exercise financial

"The shares were sold in connection with the exercise of stock options in a cashless exercise transaction."

A cashless exercise is a way for an option holder to convert stock options into actual shares without paying the purchase price in cash; instead they immediately give up a portion of the newly issued shares to cover the cost and any withholding taxes. Investors care because this process increases the number of shares available and can slightly dilute existing holdings, while also signaling how insiders or employees are realizing compensation without needing cash — similar to paying for a purchase by handing over part of what you just bought.

weighted average sale price financial

"The reported price represents a weighted average sale price for shares sold in multiple transactions."

indirect ownership financial

"GrayMatters Consulting B.V., an entity controlled by Dr. Lesage"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What insider transaction did PHVS executive Anne Lesage report?

Anne Lesage reported that an entity she controls sold 20,000 shares of Pharvaris N.V. common stock on September 17, 2026 in open-market or private transactions at a weighted average price of $38.27 per share.

Was the PHVS insider sale by Anne Lesage under a Rule 10b5-1 plan?

No. The filing indicates that no Rule 10b5-1 trading plan is affirmed for the reported transactions, and the footnotes do not state that the sale was made under such a plan.

How many PHVS shares did Anne Lesage hold after the reported transactions?

After the reported transactions, Anne Lesage is shown holding 73,969 shares indirectly through GrayMatters Consulting B.V. and 56,450 shares directly of Pharvaris N.V. common stock.

What price range did the PHVS shares sell for in the Lesage transaction?

The filing states the sales prices ranged from $38.04 to $38.65 per share, with a weighted average sale price of $38.27 for the 20,000 shares sold on September 17, 2026.

How were the PHVS shares sold by Anne Lesage’s entity related to stock options?

The footnote explains that the 20,000 shares sold were disposed of in connection with the cashless exercise of stock options, with shares sold to cover the exercise in transactions at the specified price range.

AI-generated analysis. How Rhea-AI works. Not financial advice.

Form 4 Insider Transactions: What Each Field Means →

See more from StockTitan in Google Search and AI answers. Adds StockTitan as a preferred source · opens Google

Add on Google Not now

Available on EDGAR 09/21/2026 - 03:14 PM Accepted by SEC EDGAR 09/21/2026 - 03:13 PM Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Lesage Anne

(Last) (First) (Middle)

1 CRANBERRY HILL SUITE 400

(Street)

LEXINGTON MASSACHUSETTS 02421

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
Pharvaris N.V. [ PHVS ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Early Development

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
09/17/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	09/17/2026		S		20,000	D	$38.2733(1)	73,969	I	By GrayMatters Consulting BVBA(2)
Common Stock								56,450	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. The reported price represents a weighted average sale price for shares sold in multiple transactions on the reported date. The shares were sold in connection with the exercise of stock options in a cashless exercise transaction. The sales prices for the transactions ranged from $38.04 to $38.65. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.

2. GrayMatters Consulting B.V., an entity controlled by Dr. Lesage

	/s/ Marnus Nel, Attorney-in-Fact for Anne	09/21/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)