Welcome to our dedicated page for Promis Neuroscie SEC filings (Ticker: PMN), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
The ProMIS Neurosciences Inc. (Nasdaq: PMN) SEC filings page on Stock Titan provides access to the company’s U.S. regulatory disclosures, including current reports on Form 8-K, proxy statements and other key documents. ProMIS is a clinical-stage biotechnology company focused on antibody and vaccine candidates targeting toxic misfolded protein oligomers in neurodegenerative and other misfolded protein diseases, and its filings offer detailed insight into corporate actions, governance and clinical program updates.
Through recent Form 8-K filings, ProMIS has reported material events such as the implementation of a one-for-twenty-five reverse stock split of its common shares, effective November 28, 2025, and subsequent notification from Nasdaq that the company regained compliance with the $1.00 minimum bid price requirement. Other 8-Ks describe the recommendation of an independent Data and Safety Monitoring Board to advance the PRECISE-AD Phase 1b trial of PMN310 to the final dose escalation cohort, the establishment of an at-the-market offering program, and the appointment and compensation of directors and executives.
The company’s definitive proxy statement on Schedule 14A outlines matters submitted to shareholders, including authorization of the share consolidation and procedures for a virtual special meeting. These materials provide information on share structure proposals, voting results and corporate governance practices. Additional filings reference press releases reporting quarterly financial results, which are incorporated by reference into Item 2.02 of Form 8-K.
On Stock Titan, ProMIS filings are updated in line with EDGAR and can be reviewed alongside AI-powered summaries that explain the significance of each document. Investors can quickly see how reverse stock split mechanics, Nasdaq listing compliance, at-the-market offerings, and clinical trial milestones are described in official filings. Over time, this page will also aggregate annual reports on Form 10-K, quarterly reports on Form 10-Q, and insider transaction reports on Form 4 as they are filed, helping users track both the scientific and capital markets dimensions of PMN’s development.
ProMIS Neurosciences (PMN) reported an insider option grant to Neil Cashman, who serves as a director and Chief Scientific Officer. The report shows an option to purchase 165,000 common shares with a $0.45 exercise price, granted with a transaction date of 09/22/2025. The option becomes exercisable on 09/22/2025 and expires on 09/22/2035. Vesting is specified: 25% vests on September 1, 2026 and the remainder vests ratably over the following 36 months. The Form 4 was signed by an attorney-in-fact for Mr. Cashman on 09/24/2025. The filing reflects a non-derivative underlying position of 165,000 common shares after the reported transaction.
ProMIS Neurosciences reported an insider equity award: Chief Development Officer Johanne Kaplan was granted an option to buy 165,000 common shares at a $0.45 exercise price. The option was granted on 09/22/2025, becomes exercisable beginning 09/22/2025, and expires on 09/22/2035. Under the disclosed vesting schedule, 25% of the option vests on 09/01/2026 and the remaining portion vests ratably over the following 36 months. The Form 4 was signed on behalf of Ms. Kaplan on 09/24/2025 by an attorney-in-fact.
Larry Douglas Altstiel, Chief Medical Officer and director of ProMIS Neurosciences Inc. (PMN), was granted stock options on 09/22/2025. The Form 4 reports an award of 165,000 option rights to purchase common shares at an exercise price of $0.45 per share. The instrument is an option with an expiration tied to 09/22/2035. The reporting person beneficially owns 165,000 shares following the transaction and these holdings are listed as direct ownership. Per the filing, 25% of the option shares vest on September 1, 2026 and the remainder vests ratably over the following 36 months. The Form 4 was signed by an attorney-in-fact on 09/24/2025.
ProMIS Neurosciences Inc. is soliciting votes for a virtual Special Meeting for holders of record as of September 26, 2025. The meeting will be entirely online at www.virtualshareholdermeeting.com/PMN2025SM and proxy materials are available at www.proxyvote.com and www.sedarplus.ca. The principal proposal is a Share Consolidation (reverse split) requiring approval by 66 2/3% of votes cast. The board unanimously recommends voting FOR the consolidation. The filing describes potential effects on per-share metrics, authorized shares, anti-takeover mechanisms, and U.S. and Canadian tax considerations. Broker voting and voting procedures for street-name holders are explained.
Jeremy M. Sclar, a director of ProMIS Neurosciences Inc. (PMN), reported multiple transactions in July 2025 that materially changed his beneficial holdings. On July 25, 2025 the Jeremy M. Sclar 2012 Irrevocable Family Trust (the "JS Trust") exercised 697,674 Tranche A, 697,674 Tranche B and 697,674 Tranche C purchase warrants, each converting to one common share. Although original exercise prices ranged from $2.02 to $2.50, the exercises were completed at $0.83518 per share following an offer accepted by the issuer. The JS Trust subsequently acquired, on July 29, 2025, a warrant to purchase 3,139,533 common shares exercisable at $1.25 and expiring five years after issuance. The report also shows a disposition of 65,000 common shares held through Crocker Mountain LLC.
ProMIS Neurosciences, Inc. files a shelf registration prospectus describing the offer and sale of securities and incorporating by reference multiple SEC filings, including its Annual Report on Form 10-K for the year ended December 31, 2024 and subsequent Forms 10-Q and 8-Ks. The prospectus highlights forward-looking statements and extensive risk factors, including liquidity and going-concern risks, regulatory, patent and market-competition risks, and operational impacts from global events. Corporate actions disclosed include a 60:1 reverse share split effective June 28, 2022 (all historic share numbers adjusted), a continuance to Ontario corporate law effective July 13, 2023, and listing of common shares on Nasdaq under the symbol PMN. The company also cites exemptions under the JOBS Act and limited executive compensation and auditor-attestation disclosures.
ProMIS Neurosciences Inc. reported that an independent Data and Safety Monitoring Board for its ongoing PRECISE-AD Phase 1b trial has unanimously recommended proceeding to the third and final dose-escalation cohort of PMN310, its lead therapeutic candidate for Alzheimer’s disease. The recommendation followed a review of safety data through Cohort 2, which is now fully enrolled, with no cases of amyloid-related imaging abnormalities observed so far.
The company has begun enrolling patients in Cohort 3 and remains on track to report 6‑month interim data in the second quarter of 2026 and final top-line results in the fourth quarter of 2026, according to the disclosure.
ProMIS Neurosciences Inc. entered into an at-the-market offering agreement that allows it to sell common shares with an aggregate offering price of up to $17,988,524 through H.C. Wainwright & Co. as sales agent. Any sales will be made under a Form S-3 shelf registration statement and related prospectus materials, and no shares may be sold until the registration statement is declared effective by the SEC.
The agent may sell shares on Nasdaq or other markets using customary at-the-market methods and will receive a commission of up to 3% of the gross sales proceeds. The agreement does not obligate the agent to sell a specific amount of shares, and there is no escrow or similar arrangement for proceeds. Legal opinions from McMillan LLP regarding the issuance and sale of the shares are filed as exhibits.
ProMIS Neurosciences (PMN) received a joint Schedule 13G/A disclosing that Great Point Partners, LLC, Dr. Jeffrey R. Jay and Ms. Lillian Nordahl collectively beneficially own 3,334,520 common shares, representing 9.99% of the class based on 33,378,582 shares outstanding. The reporting persons hold shared voting and dispositive power over all reported shares and disclose an aggregate of 2,645,128 shares held outright plus Pre-Funded Warrants and Warrants subject to a Beneficial Ownership Cap.
The filing explains 689,392 shares are currently exercisable under the warrants because of the ownership cap, and the Reporting Persons timely executed a Joint Filing Agreement dated August 14, 2025 to file this Schedule 13G/A jointly.
ProMIS Neurosciences (PMN) Form 3: The filing shows initial beneficial ownership by Shaf QIC LLC and Shafmaster Jonathan, each identified as a director and 10% owner. The report discloses 5,184,760 common shares held directly and three classes of warrants exercisable into common shares: 100,000 shares at $7.50 (exercisable 04/11/2028), 1,063,830 shares at $1.75 (exercisable 02/23/2029), and 4,186,049 shares at $1.25 (exercisable 07/29/2030). Some warrants include a 9.99% ownership exercise limitation.
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