[6-K] PAINREFORM LTD. Current Report (Foreign Issuer)

Rhea-AI Filing Summary

PainReform Ltd. reported that it has scheduled its Annual General Meeting of Shareholders for December 30, 2025, at 3:00 p.m. Israel time. The meeting will take place at the offices of the company’s legal counsel, Amit, Pollak, Matalon & Co., in Tel Aviv, Israel. To support the meeting, PainReform is providing a Notice and Proxy Statement and a Proxy Card for holders of ordinary shares so shareholders can review the agenda and vote their shares in advance or by proxy.

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

Form 6-K

Report of Foreign Private Issuer

Pursuant to Rule 13a-16 or 15d-16

of the Securities Exchange Act of 1934

For the month of November 2025

Commission File Number: 001-39481

PainReform Ltd.

(Translation of registrant’s name into English)

65 Yigal Alon St., Tel Aviv 6744316

Israel (Address of principal executive offices)

Indicate by check mark whether the registrant files or will file annual reports under cover Form 20-F or Form 40-F.

Form 20-F ☒         Form 40-F ☐

On November 25, 2025, PainReform Ltd. (the “Company”) announced that it will hold its Annual General Meeting of Shareholders on December 30, 2025 at 3:00 p.m. (Israel time) at the offices of the Company’s attorneys, Amit, Pollak, Matalon & Co., at APM House, 18 Raoul Wallenberg St., Building D, 6th floor, Ramat Hachayal, Tel Aviv, Israel. In connection with the meeting, the Company furnishes the following documents:

1. A copy of the Notice and Proxy Statement with respect to the Company’s Annual General Meeting of Shareholders describing the proposals to be voted upon at the meeting, the procedure for voting in person or by proxy at the meeting and various other details related to the meeting, attached hereto as Exhibit 99.1; and

2. A form of Proxy Card whereby holders of ordinary shares of the Company may vote at the meeting without attending in person, attached hereto as Exhibit 99.2.

Exhibit Index

Exhibit No.		Description
99.1		Notice and Proxy Statement with respect to the Company’s Annual General Meeting of Shareholders
99.2		Proxy Card for holders of ordinary shares with respect to the Company’s Annual General Meeting of Shareholders

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

Date: November 25, 2025	PAINREFORM LTD.
	By:	/s/ Ehud Geller
		Ehud Geller
		Executive Chairman of the Board and Interim Chief Executive Officer

FAQ

What did PainReform Ltd. (PRFX) announce in this Form 6-K?

PainReform Ltd. announced that it will hold its Annual General Meeting of Shareholders on December 30, 2025, and is furnishing related proxy materials.

When and where is PainReform Ltd.’s 2025 Annual General Meeting being held?

The meeting is scheduled for December 30, 2025 at 3:00 p.m. (Israel time) at Amit, Pollak, Matalon & Co., APM House, 18 Raoul Wallenberg St., Building D, 6th floor, Ramat Hachayal, Tel Aviv, Israel.

What documents are included with PainReform Ltd.’s AGM announcement?

The company is providing a Notice and Proxy Statement for the Annual General Meeting and a Proxy Card for holders of ordinary shares.

Who signed the PainReform Ltd. (PRFX) Form 6-K related to the AGM?

The report was signed by Ehud Geller, who serves as Executive Chairman of the Board and Interim Chief Executive Officer of PainReform Ltd.

Why are PainReform Ltd. shareholders receiving proxy materials?

Shareholders receive proxy materials so they can review the matters to be voted on at the Annual General Meeting and cast their votes, either in person or by proxy.