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Rhea-AI Filing Summary

Tectonic Therapeutic, Inc. (Nasdaq: TECX) has filed a Form S-3 shelf registration that allows the company to issue up to $400 million of common stock, preferred stock, debt securities and/or warrants. The filing also includes a dedicated $100 million at-the-market (ATM) sales agreement with TD Securities (USA) LLC, giving management flexibility to raise capital "from time to time" as clinical milestones approach.

The prospectus reiterates Tectonic’s strategy of developing biologics that modulate GPCRs via its proprietary GEODe™ platform. Lead asset TX45 (Fc-relaxin fusion) has completed a Phase 1a study showing good tolerability and a favourable PK/PD profile. In Part A of an ongoing Phase 1b hemodynamic trial in PH-HFpEF patients, TX45 achieved a 19% reduction in pulmonary capillary wedge pressure and a >30% PVR reduction in a severe sub-population, with no serious adverse events. Recruitment is under way for Part B (PH-HFrEF), and the 24-week placebo-controlled Phase 2 APEX trial dosed its first patient in October 2024; topline data are expected in 2026.

Second program TX2100, a VHH-Fc fusion for Hereditary Hemorrhagic Telangiectasia, entered IND-enabling studies in Q2 2025, with a Phase 1 start targeted for late 2025/early 2026. The company completed a reverse-merger with Legacy Tectonic in June 2024 and now qualifies as a smaller reporting company. Proceeds from any sales under the shelf will fund pipeline advancement, working capital and potential in-licensing.

As of 3 July 2025 the stock traded at $21.34 per share. While the registration itself is not a financing event, it signals possible future dilution balanced by improved funding optionality ahead of multiple clinical catalysts.

Tectonic Therapeutic, Inc. (Nasdaq: TECX) ha depositato un modulo di registrazione Form S-3 che consente all'azienda di emettere fino a 400 milioni di dollari in azioni ordinarie, azioni privilegiate, titoli di debito e/o warrant. La registrazione include anche un accordo dedicato di vendita ATM (at-the-market) da 100 milioni di dollari con TD Securities (USA) LLC, offrendo al management la flessibilità di raccogliere capitale "di volta in volta" in prossimità di tappe cliniche importanti.

Il prospetto ribadisce la strategia di Tectonic di sviluppare biologici che modulano i GPCR tramite la sua piattaforma proprietaria GEODe™. Il principale asset, TX45 (fusione Fc-relaxina), ha completato uno studio di Fase 1a che ha mostrato buona tollerabilità e un profilo PK/PD favorevole. Nella Parte A di uno studio emodinamico di Fase 1b in pazienti con PH-HFpEF, TX45 ha ottenuto una riduzione del 19% della pressione capillare polmonare a cuneo e una riduzione del PVR superiore al 30% in una sottopopolazione grave, senza eventi avversi gravi. È in corso il reclutamento per la Parte B (PH-HFrEF), e lo studio controllato con placebo di Fase 2 APEX di 24 settimane ha dosato il primo paziente nell’ottobre 2024; i dati principali sono attesi nel 2026.

Il secondo programma, TX2100, una fusione VHH-Fc per la Telangiectasia Emorragica Ereditaria, è entrato negli studi abilitanti IND nel secondo trimestre 2025, con l’avvio della Fase 1 previsto per fine 2025/inizio 2026. La società ha completato una fusione inversa con Legacy Tectonic nel giugno 2024 e ora si qualifica come smaller reporting company. I proventi derivanti da eventuali vendite nell’ambito del shelf serviranno a finanziare l’avanzamento della pipeline, il capitale circolante e potenziali licenze in ingresso.

Al 3 luglio 2025, il titolo quotava a 21,34 dollari per azione. Sebbene la registrazione in sé non rappresenti un evento di finanziamento, segnala una possibile futura diluizione bilanciata da una maggiore flessibilità di finanziamento in vista di molteplici catalizzatori clinici.

Tectonic Therapeutic, Inc. (Nasdaq: TECX) ha presentado un registro de estantería Form S-3 que permite a la compañía emitir hasta 400 millones de dólares en acciones comunes, acciones preferentes, valores de deuda y/o warrants. La presentación también incluye un acuerdo dedicado de ventas ATM (at-the-market) por 100 millones de dólares con TD Securities (USA) LLC, otorgando a la dirección la flexibilidad para recaudar capital "de vez en cuando" conforme se acercan hitos clínicos.

El prospecto reitera la estrategia de Tectonic de desarrollar biológicos que modulan los GPCR mediante su plataforma patentada GEODe™. El activo principal, TX45 (fusión Fc-relaxina), completó un estudio de Fase 1a mostrando buena tolerabilidad y un perfil PK/PD favorable. En la Parte A de un ensayo hemodinámico de Fase 1b en pacientes con PH-HFpEF, TX45 logró una reducción del 19% en la presión capilar pulmonar en cuña y una reducción de >30% en la resistencia vascular pulmonar en una subpoblación severa, sin eventos adversos graves. Está en marcha el reclutamiento para la Parte B (PH-HFrEF), y el ensayo controlado con placebo de Fase 2 APEX de 24 semanas dosificó a su primer paciente en octubre de 2024; se esperan datos principales en 2026.

El segundo programa, TX2100, una fusión VHH-Fc para la Telangiectasia Hemorrágica Hereditaria, inició estudios habilitantes IND en el segundo trimestre de 2025, con inicio de Fase 1 previsto para finales de 2025/principios de 2026. La compañía completó una fusión inversa con Legacy Tectonic en junio de 2024 y ahora califica como una smaller reporting company. Los ingresos de cualquier venta bajo el shelf financiarán el avance de la pipeline, capital de trabajo y posibles licencias entrantes.

Al 3 de julio de 2025, la acción cotizaba a 21,34 dólares por acción. Aunque el registro en sí no es un evento de financiamiento, señala una posible dilución futura equilibrada con una mayor opción de financiamiento ante múltiples catalizadores clínicos.

Tectonic Therapeutic, Inc. (나스닥: TECX)는 최대 4억 달러 규모의 보통주, 우선주, 채무 증권 및/또는 워런트를 발행할 수 있는 Form S-3 선반 등록을 제출했습니다. 이 등록에는 TD Securities (USA) LLC와의 전용 1억 달러 규모의 ATM(시장가 매도) 판매 계약도 포함되어 있어, 경영진이 임상 이정표가 다가올 때마다 자본을 조달할 수 있는 유연성을 제공합니다.

설명서에는 Tectonic이 독자적인 GEODe™ 플랫폼을 통해 GPCR을 조절하는 생물학적 제제를 개발하는 전략이 재확인되어 있습니다. 주요 자산인 TX45(Fc-릴렉신 융합체)는 내약성이 우수하고 PK/PD 프로필이 양호한 1a상 연구를 완료했습니다. 진행 중인 PH-HFpEF 환자를 대상으로 한 1b상 혈역학 시험의 파트 A에서 TX45는 폐모세혈관 쐐기압을 19% 감소시키고, 중증 하위 집단에서 >30%의 폐혈관 저항(PVR) 감소를 달성했으며 심각한 부작용은 없었습니다. 파트 B(PH-HFrEF) 모집이 진행 중이며, 24주간 위약 대조 2상 APEX 시험은 2024년 10월 첫 환자 투여를 완료했으며, 주요 결과는 2026년에 발표될 예정입니다.

두 번째 프로그램인 TX2100은 유전성 출혈성 모세혈관 확장증 치료를 위한 VHH-Fc 융합체로, 2025년 2분기에 IND 승인용 연구에 착수했으며 2025년 말~2026년 초에 1상 시험 시작을 목표로 하고 있습니다. 회사는 2024년 6월 Legacy Tectonic과 역합병을 완료했으며 현재 소규모 보고 회사(smaller reporting company)로 분류됩니다. 선반 등록을 통한 매출 수익은 파이프라인 개발, 운전자본 및 잠재적 라이선스 인에 사용될 예정입니다.

2025년 7월 3일 기준 주가는 주당 21.34달러였습니다. 등록 자체가 자금 조달 이벤트는 아니지만, 다수의 임상 촉매제를 앞두고 자금 조달 선택권이 개선됨에 따라 향후 희석 가능성을 시사합니다.

Tectonic Therapeutic, Inc. (Nasdaq : TECX) a déposé un enregistrement de type Form S-3 qui permet à la société d’émettre jusqu’à 400 millions de dollars d’actions ordinaires, d’actions privilégiées, de titres de dette et/ou de bons de souscription. Le dépôt inclut également un accord de vente ATM (at-the-market) dédié de 100 millions de dollars avec TD Securities (USA) LLC, offrant à la direction la flexibilité de lever des fonds « de temps à autre » à l’approche des jalons cliniques.

Le prospectus réaffirme la stratégie de Tectonic de développer des biologiques modulant les GPCR via sa plateforme propriétaire GEODe™. Le principal actif, TX45 (fusion Fc-relaxine), a complété une étude de Phase 1a montrant une bonne tolérance et un profil PK/PD favorable. Dans la partie A d’un essai hémodynamique de Phase 1b en cours chez des patients PH-HFpEF, TX45 a obtenu une réduction de 19 % de la pression capillaire pulmonaire en coin et une réduction du RVP de plus de 30 % dans une sous-population sévère, sans événements indésirables graves. Le recrutement est en cours pour la partie B (PH-HFrEF), et l’essai contrôlé par placebo de Phase 2 APEX de 24 semaines a traité son premier patient en octobre 2024 ; les données principales sont attendues en 2026.

Le deuxième programme, TX2100, une fusion VHH-Fc pour la télangiectasie hémorragique héréditaire, a débuté les études préparatoires IND au deuxième trimestre 2025, avec un démarrage de Phase 1 prévu fin 2025/début 2026. La société a finalisé une fusion inversée avec Legacy Tectonic en juin 2024 et est désormais qualifiée de smaller reporting company. Les recettes provenant de toute vente dans le cadre du shelf serviront à financer l’avancement du pipeline, le fonds de roulement et d’éventuelles licences entrantes.

Au 3 juillet 2025, l’action se négociait à 21,34 dollars par action. Bien que l’enregistrement ne constitue pas un événement de financement en soi, il signale une dilution possible à l’avenir, compensée par une meilleure flexibilité de financement avant plusieurs catalyseurs cliniques.

Tectonic Therapeutic, Inc. (Nasdaq: TECX) hat eine Form S-3 Shelf-Registrierung eingereicht, die dem Unternehmen erlaubt, bis zu 400 Millionen US-Dollar an Stammaktien, Vorzugsaktien, Schuldverschreibungen und/oder Warrants auszugeben. Die Einreichung beinhaltet auch eine dedizierte 100-Millionen-Dollar-At-the-Market (ATM)-Verkaufsvereinbarung mit TD Securities (USA) LLC, die dem Management die Flexibilität gibt, "von Zeit zu Zeit" Kapital zu beschaffen, wenn klinische Meilensteine anstehen.

Der Prospekt bekräftigt Tectonics Strategie, Biologika zu entwickeln, die GPCRs über die firmeneigene GEODe™-Plattform modulieren. Der führende Wirkstoff TX45 (Fc-Relaxin-Fusion) hat eine Phase-1a-Studie abgeschlossen, die eine gute Verträglichkeit und ein günstiges PK/PD-Profil zeigte. In Teil A einer laufenden Phase-1b-Hämodynamikstudie bei PH-HFpEF-Patienten erreichte TX45 eine 19%ige Reduktion des pulmonalen Kapillardrucks (PCWP) und eine >30%ige Reduktion des pulmonalen Gefäßwiderstands (PVR) in einer schweren Subpopulation, ohne schwerwiegende unerwünschte Ereignisse. Die Rekrutierung für Teil B (PH-HFrEF) läuft, und die 24-wöchige placebokontrollierte Phase-2-APEX-Studie dosierte ihren ersten Patienten im Oktober 2024; die Topline-Daten werden für 2026 erwartet.

Das zweite Programm, TX2100, eine VHH-Fc-Fusion für hereditäre hämorrhagische Teleangiektasie, begann im 2. Quartal 2025 IND-erlaubnisgebende Studien mit einem geplanten Phase-1-Start Ende 2025/Anfang 2026. Das Unternehmen schloss im Juni 2024 eine Reverse-Merger mit Legacy Tectonic ab und qualifiziert sich nun als smaller reporting company. Erlöse aus Verkäufen im Rahmen des Shelfs werden zur Pipeline-Entwicklung, für Betriebskapital und potenzielle In-Lizenzierungen verwendet.

Am 3. Juli 2025 wurde die Aktie zu 21,34 US-Dollar pro Aktie gehandelt. Obwohl die Registrierung selbst kein Finanzierungsereignis darstellt, signalisiert sie eine mögliche zukünftige Verwässerung, die durch verbesserte Finanzierungsmöglichkeiten vor mehreren klinischen Katalysatoren ausgeglichen wird.

Positive
  • $400 million shelf registration provides significant financing flexibility ahead of costly mid-stage trials.
  • Inclusion of a $100 million ATM allows opportunistic capital raises with minimal transaction lead time.
  • Lead candidate TX45 showed a 19% PCWP reduction and >30% PVR improvement with good tolerability in Phase 1b Part A.
  • Second asset TX2100 progressing through IND-enabling studies, diversifying the pipeline.
Negative
  • Potential shareholder dilution if the full $400 million in securities is issued.
  • Company remains pre-revenue and reliant on external financing for continued operations.
  • Clinical catalysts (APEX Phase 2 topline in 2026) are years away, extending the period of development risk.

Insights

TL;DR: $400 M shelf plus $100 M ATM strengthen liquidity options before Phase 2 data; dilution risk offsets financing flexibility—net neutral.

Impact assessment: The universal shelf is impactful because it pre-positions management to access meaningful capital for the costly APEX Phase 2 and upcoming TX2100 trials. However, no securities are being sold today, and utilisation will depend on market conditions. Investors should weigh:

  • Positive: Additional runway could support pivotal-enabling data without a larger, more dilutive follow-on.
  • Negative: The authorised amount (~19% of current market cap at $21.34) implies potential dilution if fully issued.

Valuation view: Shelf filings are standard for pre-commercial biotechs; I view the news as neutral (rating 0) with upside tied to forthcoming clinical read-outs rather than the registration itself.

Tectonic Therapeutic, Inc. (Nasdaq: TECX) ha depositato un modulo di registrazione Form S-3 che consente all'azienda di emettere fino a 400 milioni di dollari in azioni ordinarie, azioni privilegiate, titoli di debito e/o warrant. La registrazione include anche un accordo dedicato di vendita ATM (at-the-market) da 100 milioni di dollari con TD Securities (USA) LLC, offrendo al management la flessibilità di raccogliere capitale "di volta in volta" in prossimità di tappe cliniche importanti.

Il prospetto ribadisce la strategia di Tectonic di sviluppare biologici che modulano i GPCR tramite la sua piattaforma proprietaria GEODe™. Il principale asset, TX45 (fusione Fc-relaxina), ha completato uno studio di Fase 1a che ha mostrato buona tollerabilità e un profilo PK/PD favorevole. Nella Parte A di uno studio emodinamico di Fase 1b in pazienti con PH-HFpEF, TX45 ha ottenuto una riduzione del 19% della pressione capillare polmonare a cuneo e una riduzione del PVR superiore al 30% in una sottopopolazione grave, senza eventi avversi gravi. È in corso il reclutamento per la Parte B (PH-HFrEF), e lo studio controllato con placebo di Fase 2 APEX di 24 settimane ha dosato il primo paziente nell’ottobre 2024; i dati principali sono attesi nel 2026.

Il secondo programma, TX2100, una fusione VHH-Fc per la Telangiectasia Emorragica Ereditaria, è entrato negli studi abilitanti IND nel secondo trimestre 2025, con l’avvio della Fase 1 previsto per fine 2025/inizio 2026. La società ha completato una fusione inversa con Legacy Tectonic nel giugno 2024 e ora si qualifica come smaller reporting company. I proventi derivanti da eventuali vendite nell’ambito del shelf serviranno a finanziare l’avanzamento della pipeline, il capitale circolante e potenziali licenze in ingresso.

Al 3 luglio 2025, il titolo quotava a 21,34 dollari per azione. Sebbene la registrazione in sé non rappresenti un evento di finanziamento, segnala una possibile futura diluizione bilanciata da una maggiore flessibilità di finanziamento in vista di molteplici catalizzatori clinici.

Tectonic Therapeutic, Inc. (Nasdaq: TECX) ha presentado un registro de estantería Form S-3 que permite a la compañía emitir hasta 400 millones de dólares en acciones comunes, acciones preferentes, valores de deuda y/o warrants. La presentación también incluye un acuerdo dedicado de ventas ATM (at-the-market) por 100 millones de dólares con TD Securities (USA) LLC, otorgando a la dirección la flexibilidad para recaudar capital "de vez en cuando" conforme se acercan hitos clínicos.

El prospecto reitera la estrategia de Tectonic de desarrollar biológicos que modulan los GPCR mediante su plataforma patentada GEODe™. El activo principal, TX45 (fusión Fc-relaxina), completó un estudio de Fase 1a mostrando buena tolerabilidad y un perfil PK/PD favorable. En la Parte A de un ensayo hemodinámico de Fase 1b en pacientes con PH-HFpEF, TX45 logró una reducción del 19% en la presión capilar pulmonar en cuña y una reducción de >30% en la resistencia vascular pulmonar en una subpoblación severa, sin eventos adversos graves. Está en marcha el reclutamiento para la Parte B (PH-HFrEF), y el ensayo controlado con placebo de Fase 2 APEX de 24 semanas dosificó a su primer paciente en octubre de 2024; se esperan datos principales en 2026.

El segundo programa, TX2100, una fusión VHH-Fc para la Telangiectasia Hemorrágica Hereditaria, inició estudios habilitantes IND en el segundo trimestre de 2025, con inicio de Fase 1 previsto para finales de 2025/principios de 2026. La compañía completó una fusión inversa con Legacy Tectonic en junio de 2024 y ahora califica como una smaller reporting company. Los ingresos de cualquier venta bajo el shelf financiarán el avance de la pipeline, capital de trabajo y posibles licencias entrantes.

Al 3 de julio de 2025, la acción cotizaba a 21,34 dólares por acción. Aunque el registro en sí no es un evento de financiamiento, señala una posible dilución futura equilibrada con una mayor opción de financiamiento ante múltiples catalizadores clínicos.

Tectonic Therapeutic, Inc. (나스닥: TECX)는 최대 4억 달러 규모의 보통주, 우선주, 채무 증권 및/또는 워런트를 발행할 수 있는 Form S-3 선반 등록을 제출했습니다. 이 등록에는 TD Securities (USA) LLC와의 전용 1억 달러 규모의 ATM(시장가 매도) 판매 계약도 포함되어 있어, 경영진이 임상 이정표가 다가올 때마다 자본을 조달할 수 있는 유연성을 제공합니다.

설명서에는 Tectonic이 독자적인 GEODe™ 플랫폼을 통해 GPCR을 조절하는 생물학적 제제를 개발하는 전략이 재확인되어 있습니다. 주요 자산인 TX45(Fc-릴렉신 융합체)는 내약성이 우수하고 PK/PD 프로필이 양호한 1a상 연구를 완료했습니다. 진행 중인 PH-HFpEF 환자를 대상으로 한 1b상 혈역학 시험의 파트 A에서 TX45는 폐모세혈관 쐐기압을 19% 감소시키고, 중증 하위 집단에서 >30%의 폐혈관 저항(PVR) 감소를 달성했으며 심각한 부작용은 없었습니다. 파트 B(PH-HFrEF) 모집이 진행 중이며, 24주간 위약 대조 2상 APEX 시험은 2024년 10월 첫 환자 투여를 완료했으며, 주요 결과는 2026년에 발표될 예정입니다.

두 번째 프로그램인 TX2100은 유전성 출혈성 모세혈관 확장증 치료를 위한 VHH-Fc 융합체로, 2025년 2분기에 IND 승인용 연구에 착수했으며 2025년 말~2026년 초에 1상 시험 시작을 목표로 하고 있습니다. 회사는 2024년 6월 Legacy Tectonic과 역합병을 완료했으며 현재 소규모 보고 회사(smaller reporting company)로 분류됩니다. 선반 등록을 통한 매출 수익은 파이프라인 개발, 운전자본 및 잠재적 라이선스 인에 사용될 예정입니다.

2025년 7월 3일 기준 주가는 주당 21.34달러였습니다. 등록 자체가 자금 조달 이벤트는 아니지만, 다수의 임상 촉매제를 앞두고 자금 조달 선택권이 개선됨에 따라 향후 희석 가능성을 시사합니다.

Tectonic Therapeutic, Inc. (Nasdaq : TECX) a déposé un enregistrement de type Form S-3 qui permet à la société d’émettre jusqu’à 400 millions de dollars d’actions ordinaires, d’actions privilégiées, de titres de dette et/ou de bons de souscription. Le dépôt inclut également un accord de vente ATM (at-the-market) dédié de 100 millions de dollars avec TD Securities (USA) LLC, offrant à la direction la flexibilité de lever des fonds « de temps à autre » à l’approche des jalons cliniques.

Le prospectus réaffirme la stratégie de Tectonic de développer des biologiques modulant les GPCR via sa plateforme propriétaire GEODe™. Le principal actif, TX45 (fusion Fc-relaxine), a complété une étude de Phase 1a montrant une bonne tolérance et un profil PK/PD favorable. Dans la partie A d’un essai hémodynamique de Phase 1b en cours chez des patients PH-HFpEF, TX45 a obtenu une réduction de 19 % de la pression capillaire pulmonaire en coin et une réduction du RVP de plus de 30 % dans une sous-population sévère, sans événements indésirables graves. Le recrutement est en cours pour la partie B (PH-HFrEF), et l’essai contrôlé par placebo de Phase 2 APEX de 24 semaines a traité son premier patient en octobre 2024 ; les données principales sont attendues en 2026.

Le deuxième programme, TX2100, une fusion VHH-Fc pour la télangiectasie hémorragique héréditaire, a débuté les études préparatoires IND au deuxième trimestre 2025, avec un démarrage de Phase 1 prévu fin 2025/début 2026. La société a finalisé une fusion inversée avec Legacy Tectonic en juin 2024 et est désormais qualifiée de smaller reporting company. Les recettes provenant de toute vente dans le cadre du shelf serviront à financer l’avancement du pipeline, le fonds de roulement et d’éventuelles licences entrantes.

Au 3 juillet 2025, l’action se négociait à 21,34 dollars par action. Bien que l’enregistrement ne constitue pas un événement de financement en soi, il signale une dilution possible à l’avenir, compensée par une meilleure flexibilité de financement avant plusieurs catalyseurs cliniques.

Tectonic Therapeutic, Inc. (Nasdaq: TECX) hat eine Form S-3 Shelf-Registrierung eingereicht, die dem Unternehmen erlaubt, bis zu 400 Millionen US-Dollar an Stammaktien, Vorzugsaktien, Schuldverschreibungen und/oder Warrants auszugeben. Die Einreichung beinhaltet auch eine dedizierte 100-Millionen-Dollar-At-the-Market (ATM)-Verkaufsvereinbarung mit TD Securities (USA) LLC, die dem Management die Flexibilität gibt, "von Zeit zu Zeit" Kapital zu beschaffen, wenn klinische Meilensteine anstehen.

Der Prospekt bekräftigt Tectonics Strategie, Biologika zu entwickeln, die GPCRs über die firmeneigene GEODe™-Plattform modulieren. Der führende Wirkstoff TX45 (Fc-Relaxin-Fusion) hat eine Phase-1a-Studie abgeschlossen, die eine gute Verträglichkeit und ein günstiges PK/PD-Profil zeigte. In Teil A einer laufenden Phase-1b-Hämodynamikstudie bei PH-HFpEF-Patienten erreichte TX45 eine 19%ige Reduktion des pulmonalen Kapillardrucks (PCWP) und eine >30%ige Reduktion des pulmonalen Gefäßwiderstands (PVR) in einer schweren Subpopulation, ohne schwerwiegende unerwünschte Ereignisse. Die Rekrutierung für Teil B (PH-HFrEF) läuft, und die 24-wöchige placebokontrollierte Phase-2-APEX-Studie dosierte ihren ersten Patienten im Oktober 2024; die Topline-Daten werden für 2026 erwartet.

Das zweite Programm, TX2100, eine VHH-Fc-Fusion für hereditäre hämorrhagische Teleangiektasie, begann im 2. Quartal 2025 IND-erlaubnisgebende Studien mit einem geplanten Phase-1-Start Ende 2025/Anfang 2026. Das Unternehmen schloss im Juni 2024 eine Reverse-Merger mit Legacy Tectonic ab und qualifiziert sich nun als smaller reporting company. Erlöse aus Verkäufen im Rahmen des Shelfs werden zur Pipeline-Entwicklung, für Betriebskapital und potenzielle In-Lizenzierungen verwendet.

Am 3. Juli 2025 wurde die Aktie zu 21,34 US-Dollar pro Aktie gehandelt. Obwohl die Registrierung selbst kein Finanzierungsereignis darstellt, signalisiert sie eine mögliche zukünftige Verwässerung, die durch verbesserte Finanzierungsmöglichkeiten vor mehreren klinischen Katalysatoren ausgeglichen wird.

SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Estimated average burden
hours per response: 0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Tucci Angela

(Last) (First) (Middle)
C/O PROGRESS SOFTWARE CORPORATION
15 WAYSIDE ROAD, SUITE 400

(Street)
BURLINGTON MA 01803

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
PROGRESS SOFTWARE CORP /MA [ PRGS ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
X Director 10% Owner
Officer (give title below) Other (specify below)
3. Date of Earliest Transaction (Month/Day/Year)
07/02/2025
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 07/02/2025 A 4,175(1) A $53.9 45,259 D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Explanation of Responses:
1. Represents restricted stock units issued to the Reporting Person by Progress Software Corporation (the "Company") as the fiscal year 2025 equity retainer for the Reporting Person's services as a director of the Company during such period. These restricted stock units were issued in accordance with the Company's Director Compensation Plan pursuant to the Company's 2008 Stock Option and Incentive Plan and are payable upon vest on a one-for-one basis exclusively in common stock on the earlier of a change in control of the Company or the date of the Company's 2026 Annual Meeting of Stockholders, subject to the Reporting Person's continued service on the board of directors of the Company until such date.
Remarks:
YuFan Stephanie Wang, Attorney-in-Fact 07/07/2025
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

How much capital can Tectonic Therapeutic (TECX) raise under the new shelf registration?

The Form S-3 allows the company to issue up to $400 million in common stock, preferred stock, debt securities and/or warrants.

What is the size of the at-the-market (ATM) program with TD Securities?

The ATM facility permits sales of up to $100 million of common stock, included within the $400 million shelf capacity.

What recent clinical results has TX45 reported?

In Phase 1b Part A, TX45 achieved a 19% reduction in pulmonary capillary wedge pressure and demonstrated >30% PVR reduction in a severe sub-group, with no serious adverse events.

When are topline results from the APEX Phase 2 trial expected?

Tectonic projects 2026 for APEX Phase 2 topline data in PH-HFpEF.

How will proceeds from any securities sales be used?

The company plans to fund continued clinical development, working capital and potential in-licensing or acquisitions, with exact allocations detailed in future prospectus supplements.
Progress Soft

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2.27B
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Software - Infrastructure
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United States
BURLINGTON