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[8-K] Prelude Therapeutics Inc Reports Material Event

Filing Impact
(Moderate)
Filing Sentiment
(Neutral)
Form Type
8-K

Prelude Therapeutics announced a Board transition. Mardi Dier, a Class III director, notified the Company of her resignation effective October 17, 2025, and her decision was not due to any disagreement on operations, policies, or practices.

Effective the same date, the Board appointed Katina Dorton, J.D., MBA as a Class III director and named her Chair of the Audit Committee. She will serve until the 2026 Annual Meeting of Stockholders and until a successor is elected and qualified. In line with director compensation policy, Ms. Dorton received non-incentive stock options to purchase up to 76,000 shares, vesting one‑thirty‑sixth monthly over three years, subject to continued service. The Company furnished a press release as Exhibit 99.1.

Prelude Therapeutics ha annunciato una transizione del Consiglio. Mardi Dier, una direttrice di Classe III, ha comunicato all'azienda le proprie dimissioni con effetto dal October 17, 2025, e la sua decisione non è dovuta a disaccordi su operazioni, politiche o pratiche.

All'effettivo stesso data, il Consiglio ha nominato Katina Dorton, J.D., MBA come direttrice di Classe III e l'ha nominata Presidente del Comitato di Revisione Contabile. Servirà fino all'Assemblea Annuale degli Azionisti del 2026 e fino all'elezione e qualificazione del suo successore. In linea con la politica di compensazione dei direttori, la signora Dorton ha ricevuto opzioni non legate a incentivi per l'acquisto di fino a 76.000 azioni, vesting mensile di un trentasei su tre anni, soggetto al prosieguo del servizio. L'azienda ha fornito un comunicato stampa come Exhibit 99.1.

Prelude Therapeutics anunció una transición en la Junta. Mardi Dier, una directora de Clase III, notificó a la Compañía su renuncia con efecto a partir del 17 de octubre de 2025, y su decisión no se debió a ningún desacuerdo sobre operaciones, políticas o prácticas.

Con efecto a la misma fecha, la Junta designó a Katina Dorton, J.D., MBA como directora de Clase III y la nombró Presidenta del Comité de Auditoría. Servirá hasta la Reunión Anual de Accionistas de 2026 y hasta que se elija y capacite a un sucesor. De acuerdo con la política de compensación de directores, la Sra. Dorton recibió opciones de compra de acciones sin incentivo para adquirir hasta 76,000 acciones, con vesting de un treinta y seisavo mensual durante tres años, sujeto a la continuación del servicio. La Compañía proporcionó un comunicado de prensa como Exhibit 99.1.

Prelude Therapeutics는 이사회 이양을 발표했습니다. Class III 이사인 Mardi Dier는 회사에 대해 2025년 10월 17일자로 사임 통지를 하였으며, 그의 결정은 운영, 정책 또는 관행에 대한 이견 때문이 아닙니다.

같은 날짜로 이사회는 Katina Dorton, J.D., MBA를 Class III 이사로 선임하고 감사위원회의 의장을 임명했습니다. 그녀는 2026년 정기 주주총회까지 재직하며 후임자가 선출되고 자격을 갖출 때까지 serves합니다. 이사 보상 정책에 따라 Dorton 여사는 최대 76,000주의 주식 매입 옵션을 받았으며, 3년 동안 매달 1/36씩 vesting이 진행됩니다(계속 근무에 의함). 회사는 Exhibit 99.1로 보도자료를 제공했습니다.

Prelude Therapeutics a annoncé une transition du conseil d'administration. Mardi Dier, une administratrice de Classe III, a informé la Société de sa démission à compter du 17 octobre 2025, et sa décision ne résulte pas d'un désaccord sur les opérations, les politiques ou les pratiques.

À la même date, le Conseil a nommé Katina Dorton, J.D., MBA en tant qu'administratrice de Classe III et l'a nommée Présidente du comité d'audit. Elle exercera ses fonctions jusqu'à l'Assemblée annuelle des actionnaires de 2026 et jusqu'à ce qu'un successeur soit élu et qualifié. Conformément à la politique de rémunération des administrateurs, Mme Dorton a reçu des options d'achat d'actions non incitatives pour acheter jusqu'à 76 000 actions, avec une vesting mensuelle de un sur trente-six sur trois ans, sous réserve de la poursuite du mandat. La société a fourni un communiqué de presse en tant que Exhibit 99.1.

Prelude Therapeutics kündigte eine Vorstandswechsel an. Mardi Dier, eine Direktorin der Klasse III, informierte das Unternehmen mit Wirkung zum 17. Oktober 2025 von ihrem Rücktritt, und ihre Entscheidung beruhte nicht auf Meinungsverschiedenheiten in Bezug auf Betrieb, Politik oder Praxis.

Gleichzeitig mit diesem Datum ernannte der Vorstand Katina Dorton, J.D., MBA zur Direktorin der Klasse III und benannte sie zur Vorsitzenden des Prüfungsausschusses. Sie wird bis zur Hauptversammlung 2026 und bis zur Wahl und Qualifikation einer Nachfolgerin dienen. Im Einklang mit der Vergütungsrichtlinie für Direktoren erhielt Frau Dorton nicht incentivierte Aktienoptionen zum Erwerb von bis zu 76.000 Aktien, die monatlich in einem Sechsunddreißigstel über drei Jahre vesten, vorbehaltlich weiterer Dienste. Das Unternehmen legte eine Pressemitteilung als Exhibit 99.1 vor.

Prelude Therapeutics أعلنت عن انتقال في مجلس الإدارة. نبهت ماردی دوران، وهي مدير/ة من الصف الثالث، الشركة باستقالتها اعتباراً من 17 أكتوبر 2025، ولم يكن قرارها بسبب أي خلاف يتعلق بالعمليات أو السياسات أو الممارسات.

وعلى نفس التاريخ، عيّن المجلس Katina Dorton, J.D., MBA كعضو مجلس من الصف الثالث وسمّاها رئيسة لجنة التدقيق. ستستمر في الخدمة حتى اجتماع المساهمين السنوي لعام 2026 وحتى انتخاب وتأهيل خلف لها. وبالتوافق مع سياسة تعويض المديرين، تلقت السيدة Dorton خيارات شراء أسهم غير حافزة لشراء حتى 76,000 سهم، مع إتمام vesting شهرياً بمعدل واحد من ستة وثلاثين على مدى ثلاث سنوات، رهناً باستمرار الخدمة. زوّدت الشركة بياناً صحفياً ك Exhibit 99.1.

Prelude Therapeutics 宣布了董事会的过渡。作为 Class III 董事的 Mardi Dier 已通知公司自 2025年10月17日 起辞任,其决定并非由于在运营、政策或做法方面存在分歧。

同日,董事会任命 Katina Dorton, J.D., MBA 为 Class III 董事,并任命她为审计委员会主席。她将任职至2026年股东年度大会,并直到选出并具备资格的继任者。根据董事报酬政策,Dorton 女士获得了购买最多 76,000 股的非激励性股票期权,按每月1/36的比例在三年内归属,前提是继续任职。公司已将新闻稿作为 Exhibit 99.1 提供。

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Insights

Board refresh with new Audit Chair; routine equity grant.

Prelude Therapeutics disclosed an orderly director change: Mardi Dier resigned, and Katina Dorton joined as a Class III director and will chair the Audit Committee. The filing states the resignation was not due to any disagreement, indicating routine governance turnover.

Dorton's background spans finance, law, and healthcare, aligning with audit oversight responsibilities. The equity award—options to purchase up to 76,000 shares—follows the company’s non‑employee director policy, with monthly vesting over three years tied to continued service.

The press release was furnished under Regulation FD. Actual governance impact will be reflected through future committee activities and disclosures in subsequent filings.

Prelude Therapeutics ha annunciato una transizione del Consiglio. Mardi Dier, una direttrice di Classe III, ha comunicato all'azienda le proprie dimissioni con effetto dal October 17, 2025, e la sua decisione non è dovuta a disaccordi su operazioni, politiche o pratiche.

All'effettivo stesso data, il Consiglio ha nominato Katina Dorton, J.D., MBA come direttrice di Classe III e l'ha nominata Presidente del Comitato di Revisione Contabile. Servirà fino all'Assemblea Annuale degli Azionisti del 2026 e fino all'elezione e qualificazione del suo successore. In linea con la politica di compensazione dei direttori, la signora Dorton ha ricevuto opzioni non legate a incentivi per l'acquisto di fino a 76.000 azioni, vesting mensile di un trentasei su tre anni, soggetto al prosieguo del servizio. L'azienda ha fornito un comunicato stampa come Exhibit 99.1.

Prelude Therapeutics anunció una transición en la Junta. Mardi Dier, una directora de Clase III, notificó a la Compañía su renuncia con efecto a partir del 17 de octubre de 2025, y su decisión no se debió a ningún desacuerdo sobre operaciones, políticas o prácticas.

Con efecto a la misma fecha, la Junta designó a Katina Dorton, J.D., MBA como directora de Clase III y la nombró Presidenta del Comité de Auditoría. Servirá hasta la Reunión Anual de Accionistas de 2026 y hasta que se elija y capacite a un sucesor. De acuerdo con la política de compensación de directores, la Sra. Dorton recibió opciones de compra de acciones sin incentivo para adquirir hasta 76,000 acciones, con vesting de un treinta y seisavo mensual durante tres años, sujeto a la continuación del servicio. La Compañía proporcionó un comunicado de prensa como Exhibit 99.1.

Prelude Therapeutics는 이사회 이양을 발표했습니다. Class III 이사인 Mardi Dier는 회사에 대해 2025년 10월 17일자로 사임 통지를 하였으며, 그의 결정은 운영, 정책 또는 관행에 대한 이견 때문이 아닙니다.

같은 날짜로 이사회는 Katina Dorton, J.D., MBA를 Class III 이사로 선임하고 감사위원회의 의장을 임명했습니다. 그녀는 2026년 정기 주주총회까지 재직하며 후임자가 선출되고 자격을 갖출 때까지 serves합니다. 이사 보상 정책에 따라 Dorton 여사는 최대 76,000주의 주식 매입 옵션을 받았으며, 3년 동안 매달 1/36씩 vesting이 진행됩니다(계속 근무에 의함). 회사는 Exhibit 99.1로 보도자료를 제공했습니다.

Prelude Therapeutics a annoncé une transition du conseil d'administration. Mardi Dier, une administratrice de Classe III, a informé la Société de sa démission à compter du 17 octobre 2025, et sa décision ne résulte pas d'un désaccord sur les opérations, les politiques ou les pratiques.

À la même date, le Conseil a nommé Katina Dorton, J.D., MBA en tant qu'administratrice de Classe III et l'a nommée Présidente du comité d'audit. Elle exercera ses fonctions jusqu'à l'Assemblée annuelle des actionnaires de 2026 et jusqu'à ce qu'un successeur soit élu et qualifié. Conformément à la politique de rémunération des administrateurs, Mme Dorton a reçu des options d'achat d'actions non incitatives pour acheter jusqu'à 76 000 actions, avec une vesting mensuelle de un sur trente-six sur trois ans, sous réserve de la poursuite du mandat. La société a fourni un communiqué de presse en tant que Exhibit 99.1.

Prelude Therapeutics kündigte eine Vorstandswechsel an. Mardi Dier, eine Direktorin der Klasse III, informierte das Unternehmen mit Wirkung zum 17. Oktober 2025 von ihrem Rücktritt, und ihre Entscheidung beruhte nicht auf Meinungsverschiedenheiten in Bezug auf Betrieb, Politik oder Praxis.

Gleichzeitig mit diesem Datum ernannte der Vorstand Katina Dorton, J.D., MBA zur Direktorin der Klasse III und benannte sie zur Vorsitzenden des Prüfungsausschusses. Sie wird bis zur Hauptversammlung 2026 und bis zur Wahl und Qualifikation einer Nachfolgerin dienen. Im Einklang mit der Vergütungsrichtlinie für Direktoren erhielt Frau Dorton nicht incentivierte Aktienoptionen zum Erwerb von bis zu 76.000 Aktien, die monatlich in einem Sechsunddreißigstel über drei Jahre vesten, vorbehaltlich weiterer Dienste. Das Unternehmen legte eine Pressemitteilung als Exhibit 99.1 vor.

0001678660false00016786602025-10-152025-10-15

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

FORM 8-K

 

CURRENT REPORT

Pursuant to Section 13 or 15(d)

of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): October 15, 2025

 

Prelude Therapeutics Incorporated

(Exact Name of Registrant as Specified in its Charter)

 

 

 

 

 

 

Delaware

 

001-39527

 

81-1384762

(State or other jurisdiction of
incorporation or organization)

 

(Commission
File Number)

 

(I.R.S. Employer
Identification No.)

 

 

 

175 Innovation Boulevard

Wilmington, Delaware

 

19805

(Address of principal executive offices)

 

(Zip Code)

Registrant’s telephone number, including area code: (302) 467-1280

Not Applicable

(Former Name or Former Address, if Changed Since Last Report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

 

 

 

 

 

Title of each class

 

Trading
Symbol(s)

 

Name of each exchange on which registered

Common Stock, $0.0001 par value per share

 

PRLD

 

Nasdaq Global Select Market

 

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.


Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

 

On October 15 , 2025, Mardi Dier, a Class III member of the Board of Directors (the “Board”) of Prelude Therapeutics Incorporated (the “Company”), provided notice of her intention to resign from the Board, effective October 17, 2025 (the “Effective Date”). Ms. Dier's decision to resign was not the result of any disagreement with the Company on any matter relating to its operations, policies or practices.

On October 17, 2025, upon the recommendation of the Nominating and Corporate Governance Committee (the “NGC Committee”) of the Board, the Board appointed Katina Dorton, J.D., MBA, as a Class III director effective as of the Effective Date. Ms. Dorton also was appointed as a member of the Audit Committee of the Board, and will serve as Chair of the Audit Committee. Ms. Dorton will serve until the 2026 Annual Meeting of Stockholders and until her successor is duly elected and qualified or until her earlier resignation or removal.

Ms. Dorton most recently served as chief financial officer of NodThera, a private biotechnology company, from 2020 to 2022. Earlier in her career, she was a healthcare investment banker at Morgan Stanley and Needham & Company, and she practiced M&A and securities law at Sullivan and Cromwell. In addition, Ms. Dorton currently serves on the boards of directors of Fulcrum Therapeutics Inc. (Nasdaq: FULC) and TScan Therapeutics Inc. (Nasdaq: TCRX) positions she has held since 2019 and 2021, respectively. Ms. Dorton holds a Bachelor of Arts degree from Duke University, a Master of Business Administration degree from George Washington University and a Juris Doctor degree from the University of Virginia. Ms. Dorton’s qualifications to serve on our Board include her more than 30 years of finance and healthcare experience in leadership positions in areas of fundraising, mergers and acquisitions, and business development. There is no arrangement or understanding between Ms. Dorton and any other person pursuant to which Ms. Dorton was selected as a director. The Company is not aware of any related party transactions or relationships between Ms. Dorton and the Company that would require disclosure under Item 404(a) of Regulation S-K.

In connection with her appointment to the Board, and in accordance with the Company’s current director compensation policy, Ms. Dorton will receive compensation for her service as a director in accordance with the Company’s compensation policy for non-employee directors, and the Board granted Ms. Dorton non-incentive stock options (the “Options”) to purchase up to 76,000 shares of the Company’s common stock under the terms of the Company’s 2020 Equity Incentive Plan, with such Options vesting over a three year period equally one-thirty-sixth per month, subject to Ms. Dorton's continued service to the Company on each vesting date.

The Company will enter into an indemnity agreement with Ms. Dorton in the form that it has entered into with its other directors and that is filed as Exhibit 10.1 to the Company’s registration statement on Form S-1 (File No. 333-248628).

 

Item 7.01 Regulation FD Disclosure.

On October 17, 2025, the Company issued a press release announcing the appointment of Ms. Dorton to the Board. A copy of the press release is attached hereto as Exhibit 99.1 and is incorporated herein by reference.

The information in this Current Report on Form 8-K and in Exhibit 99.1 attached hereto is being furnished, but shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (“Exchange Act”), and is not incorporated by reference into any filing of the Company under the Securities Act of 1933, as amended, or the Exchange Act, whether made before or after the date hereof, regardless of any general incorporation language in such filing.

 

 

 

 

 

Exhibit
Number

 

Description

99.1

 

Press release announcing the appointment of Katina Dorton, dated October 17, 2025

104

 

Cover Page Interactive Data File (embedded within the Inline XBRL Document)

 


SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

 

 

 

PRELUDE THERAPEUTICS INCORPORATED

 

 

 

 

 

Date: October 17, 2025

By:

/s/ Bryant Lim

 

 

Bryant Lim

 

 

Chief Legal Officer, Corporate Secretary, and Chief Financial Officer

 


FAQ

What board change did PRLD announce?

Mardi Dier resigned as a Class III director effective October 17, 2025, and Katina Dorton was appointed as a Class III director and Audit Committee Chair effective the same date.

Did Mardi Dier resign due to a disagreement with PRLD?

No. The company stated her decision was not due to any disagreement on operations, policies, or practices.

What is Katina Dorton’s role on PRLD’s Board?

She was appointed a Class III director and will serve as Chair of the Audit Committee.

How long will Katina Dorton serve on PRLD’s Board?

She will serve until the 2026 Annual Meeting of Stockholders and until a successor is elected and qualified.

What equity award did PRLD grant to Katina Dorton?

Non‑incentive stock options to purchase up to 76,000 shares, vesting one‑thirty‑sixth per month over three years, subject to continued service.

Did PRLD issue a press release about the appointment?

Yes. A press release announcing Ms. Dorton’s appointment was furnished as Exhibit 99.1.
Prelude Therapeutics Inc

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