STOCK TITAN

[Form 4] Prime Medicine, Inc. Insider Trading Activity

Filing Impact
(Low)
Filing Sentiment
(Neutral)
Form Type
4
Rhea-AI Filing Summary

Reine Allan, who is listed as both Chief Executive Officer and a director of Prime Medicine, reported a one-time repricing of certain outstanding stock options effective August 1, 2025. Stockholders approved reducing the per-share exercise price of the affected options to $4.04 from the prior $6.80, aligning the exercise price with the closing market price on the repricing date. The filing shows 850,000 options were repriced and remain governed by their original terms except for the new exercise price; these awards were issued under the 2019 and/or 2022 stock plans and retain their existing vesting schedules and expiration dates (noted as 01/17/2034). The repriced options become exercisable only as they vest and subject to continued service.

Reine Allan, indicata come Amministratore delegato e membro del consiglio di amministrazione di Prime Medicine, ha comunicato un riprezzo una tantum di alcune opzioni su azioni in essere, con efficacia August 1, 2025. Gli azionisti hanno approvato la riduzione del prezzo di esercizio per azione delle opzioni interessate a $4.04 dall'precedente $6.80, allineando il prezzo di esercizio al prezzo di chiusura di mercato nella data del riprezzo. La documentazione indica che sono state riallocate 850,000 opzioni, che rimangono soggette ai termini originari fatta eccezione per il nuovo prezzo di esercizio; tali assegni sono stati emessi ai sensi dei piani azionari 2019 e/o 2022 e mantengono i calendari di vesting e le date di scadenza esistenti (indicate come 01/17/2034). Le opzioni ricalibrate potranno essere esercitate solo al verificarsi del vesting e subordinatamente alla continuazione del rapporto di servizio.

Reine Allan, registrada como Directora Ejecutiva y miembro del consejo de Prime Medicine, informó un reajuste único del precio de determinadas opciones sobre acciones en circulación, con efecto August 1, 2025. Los accionistas aprobaron reducir el precio de ejercicio por acción de las opciones afectadas a $4.04 desde $6.80, alineando así el precio de ejercicio con el precio de cierre de mercado en la fecha del reajuste. La presentación muestra que se reajustaron 850,000 opciones, que siguen regidas por sus términos originales salvo por el nuevo precio de ejercicio; estos premios se emitieron bajo los planes de acciones de 2019 y/o 2022 y conservan sus calendarios de vesting y sus fechas de vencimiento existentes (indicadas como 01/17/2034). Las opciones reajustadas solo podrán ejercerse a medida que se vayan adquiriendo y están sujetas a la continuidad del servicio.

Reine Allan은 Prime Medicine의 최고경영자이자 이사로 등재되어 있으며, 특정 미결 주식옵션에 대한 일회성 재가격August 1, 2025부로 보고했습니다. 주주들은 해당 옵션의 주당 행사가를 이전의 $6.80에서 $4.04로 인하하는 것을 승인했으며, 이는 재가격일의 종가에 행사가를 일치시킨 것입니다. 제출 서류에 따르면 850,000개의 옵션이 재가격되었고, 새로운 행사가를 제외한 원래의 조건은 그대로 유지됩니다; 이러한 수여는 2019년 및/또는 2022년 주식계획에 따라 발행되었으며 기존의 베스팅 일정과 만료일(표기: 01/17/2034)을 유지합니다. 재가격된 옵션은 베스팅되는 만큼만 행사할 수 있으며 계속 근무 조건이 충족되어야 행사 가능합니다.

Reine Allan, répertoriée à la fois comme directrice générale et comme administratrice de Prime Medicine, a déclaré une revalorisation unique du prix de certaines options sur actions en circulation, effective August 1, 2025. Les actionnaires ont approuvé la réduction du prix d'exercice par action des options concernées à $4.04 au lieu de $6.80, alignant ainsi le prix d'exercice sur le cours de clôture à la date de la revalorisation. Le dossier indique que 850,000 options ont été revalorisées et restent soumises à leurs conditions initiales, à l'exception du nouveau prix d'exercice ; ces attributions ont été émises dans le cadre des plans d'actions de 2019 et/ou 2022 et conservent leurs calendriers d'acquisition (vesting) et leurs dates d'expiration existants (indiqués comme 01/17/2034). Les options revalorisées ne deviennent exerçables que lorsqu'elles sont acquises et sous réserve de la poursuite du service.

Reine Allan, die sowohl als Chief Executive Officer als auch als Direktorin von Prime Medicine geführt wird, meldete eine einmalige Neubepreisung bestimmter ausstehender Aktienoptionen mit Wirkung zum August 1, 2025. Die Aktionäre genehmigten die Senkung des Ausübungspreises pro Aktie der betroffenen Optionen von zuvor $6.80 auf $4.04, wodurch der Ausübungspreis dem Schlusskurs am Tag der Neubepreisung angeglichen wird. Die Einreichung weist aus, dass 850,000 Optionen neu bepreist wurden und weiterhin den ursprünglichen Bedingungen unterliegen, abgesehen vom neuen Ausübungspreis; diese Zuweisungen wurden im Rahmen der Aktienpläne 2019 und/oder 2022 gewährt und behalten ihre bestehenden Vesting-Zeitpläne und Verfallsdaten (angegeben als 01/17/2034) bei. Die neu bepreisten Optionen sind nur ausübbar, wenn sie vesten und vorbehaltlich der fortgesetzten Dienstzeit.

Positive
  • Stockholder approval was obtained for the repricing, indicating formal governance process compliance
  • Exercise price aligned to market ($4.04), which can restore intended economic incentive for the option holder
  • Vesting and other original terms remain unchanged, limiting unexpected changes to award structure
Negative
  • Large block repriced (850,000 options), which could lead to future dilution if exercised
  • Represents additional executive compensation without disclosure here of any offsetting performance conditions or expense details
  • Repricing from $6.80 to $4.04 indicates prior strikes were substantially underwater, which some investors view negatively

Insights

TL;DR: Executive options were materially repriced to market, benefitting the holder while preserving prior vesting and term conditions.

The Form 4 documents a one-time board- and stockholder-approved adjustment that lowered the exercise price on 850,000 options held by the CEO to $4.04 from $6.80. This action preserves the original vesting schedule and expiration (01/17/2034) and was executed under the company's 2019 and/or 2022 equity plans. From a capital-markets perspective, the repricing reduces the strike gap and increases the likelihood these options will be exercised if the share price rises above $4.04, which may modestly increase future dilution when exercised but does not change current outstanding share count. The filing is procedural and compensatory in nature rather than an operational indicator.

TL;DR: Shareholder-approved option repricing raises governance questions about retention, alignment, and disclosure but follows formal plan procedures.

The disclosure confirms stockholder approval for a repricing and notes that all other option terms remain in force. The affected awards totaling 850,000 options were adjusted to the closing market price of $4.04 on the repricing date and remain subject to vesting and continued service. While the filing shows proper procedural steps and explicit plan authority, investors concerned with governance will note the grant size and the executive beneficiary. The document provides clear mechanics but no commentary on shareholder rationale or incremental compensation expense.

Reine Allan, indicata come Amministratore delegato e membro del consiglio di amministrazione di Prime Medicine, ha comunicato un riprezzo una tantum di alcune opzioni su azioni in essere, con efficacia August 1, 2025. Gli azionisti hanno approvato la riduzione del prezzo di esercizio per azione delle opzioni interessate a $4.04 dall'precedente $6.80, allineando il prezzo di esercizio al prezzo di chiusura di mercato nella data del riprezzo. La documentazione indica che sono state riallocate 850,000 opzioni, che rimangono soggette ai termini originari fatta eccezione per il nuovo prezzo di esercizio; tali assegni sono stati emessi ai sensi dei piani azionari 2019 e/o 2022 e mantengono i calendari di vesting e le date di scadenza esistenti (indicate come 01/17/2034). Le opzioni ricalibrate potranno essere esercitate solo al verificarsi del vesting e subordinatamente alla continuazione del rapporto di servizio.

Reine Allan, registrada como Directora Ejecutiva y miembro del consejo de Prime Medicine, informó un reajuste único del precio de determinadas opciones sobre acciones en circulación, con efecto August 1, 2025. Los accionistas aprobaron reducir el precio de ejercicio por acción de las opciones afectadas a $4.04 desde $6.80, alineando así el precio de ejercicio con el precio de cierre de mercado en la fecha del reajuste. La presentación muestra que se reajustaron 850,000 opciones, que siguen regidas por sus términos originales salvo por el nuevo precio de ejercicio; estos premios se emitieron bajo los planes de acciones de 2019 y/o 2022 y conservan sus calendarios de vesting y sus fechas de vencimiento existentes (indicadas como 01/17/2034). Las opciones reajustadas solo podrán ejercerse a medida que se vayan adquiriendo y están sujetas a la continuidad del servicio.

Reine Allan은 Prime Medicine의 최고경영자이자 이사로 등재되어 있으며, 특정 미결 주식옵션에 대한 일회성 재가격August 1, 2025부로 보고했습니다. 주주들은 해당 옵션의 주당 행사가를 이전의 $6.80에서 $4.04로 인하하는 것을 승인했으며, 이는 재가격일의 종가에 행사가를 일치시킨 것입니다. 제출 서류에 따르면 850,000개의 옵션이 재가격되었고, 새로운 행사가를 제외한 원래의 조건은 그대로 유지됩니다; 이러한 수여는 2019년 및/또는 2022년 주식계획에 따라 발행되었으며 기존의 베스팅 일정과 만료일(표기: 01/17/2034)을 유지합니다. 재가격된 옵션은 베스팅되는 만큼만 행사할 수 있으며 계속 근무 조건이 충족되어야 행사 가능합니다.

Reine Allan, répertoriée à la fois comme directrice générale et comme administratrice de Prime Medicine, a déclaré une revalorisation unique du prix de certaines options sur actions en circulation, effective August 1, 2025. Les actionnaires ont approuvé la réduction du prix d'exercice par action des options concernées à $4.04 au lieu de $6.80, alignant ainsi le prix d'exercice sur le cours de clôture à la date de la revalorisation. Le dossier indique que 850,000 options ont été revalorisées et restent soumises à leurs conditions initiales, à l'exception du nouveau prix d'exercice ; ces attributions ont été émises dans le cadre des plans d'actions de 2019 et/ou 2022 et conservent leurs calendriers d'acquisition (vesting) et leurs dates d'expiration existants (indiqués comme 01/17/2034). Les options revalorisées ne deviennent exerçables que lorsqu'elles sont acquises et sous réserve de la poursuite du service.

Reine Allan, die sowohl als Chief Executive Officer als auch als Direktorin von Prime Medicine geführt wird, meldete eine einmalige Neubepreisung bestimmter ausstehender Aktienoptionen mit Wirkung zum August 1, 2025. Die Aktionäre genehmigten die Senkung des Ausübungspreises pro Aktie der betroffenen Optionen von zuvor $6.80 auf $4.04, wodurch der Ausübungspreis dem Schlusskurs am Tag der Neubepreisung angeglichen wird. Die Einreichung weist aus, dass 850,000 Optionen neu bepreist wurden und weiterhin den ursprünglichen Bedingungen unterliegen, abgesehen vom neuen Ausübungspreis; diese Zuweisungen wurden im Rahmen der Aktienpläne 2019 und/oder 2022 gewährt und behalten ihre bestehenden Vesting-Zeitpläne und Verfallsdaten (angegeben als 01/17/2034) bei. Die neu bepreisten Optionen sind nur ausübbar, wenn sie vesten und vorbehaltlich der fortgesetzten Dienstzeit.

SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Estimated average burden
hours per response: 0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Reine Allan

(Last) (First) (Middle)
C/O PRIME MEDICINE, INC.
60 FIRST STREET

(Street)
CAMBRIDGE MA 02141

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
Prime Medicine, Inc. [ PRME ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
X Director 10% Owner
X Officer (give title below) Other (specify below)
Chief Executive Officer
3. Date of Earliest Transaction (Month/Day/Year)
08/01/2025
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (right to buy) $6.8 08/01/2025 D(1) 850,000 (2) 01/17/2034 Common Stock 850,000 (1) 0 D
Stock Option (right to buy) $4.04 08/01/2025 A(1) 850,000 (2) 01/17/2034 Common Stock 850,000 (1) 850,000 D
Explanation of Responses:
1. Effective as of August 1, 2025 (the "Repricing Date"), the Issuer's stockholders approved a one-time repricing of certain outstanding stock options (the "Repriced Options") granted under the Issuer's 2019 Stock Option and Grant Plan, as amended (the "2019 Plan") and/or the 2022 Stock Option and Incentive Plan (the "2022 Plan" and, together with the 2019 Plan, the "Plans"), which reduced the per share exercise price of each Repriced Option to $4.04, representing the closing price of the Issuer's common stock on The Nasdaq Global Market on the Repricing Date (the "Option Repricing"). Except as modified by the Option Repricing, all other terms and conditions of the Repriced Options, including, without limitation, any provisions with respect to vesting and term of the Repriced Options, remain in full force and effect.
2. This stock option award was issued pursuant to the 2019 Plan and/or the 2022 Plan, as applicable, and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form 4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date.
Remarks:
/s/ Ryan Brown, attorney-in-fact 08/05/2025
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What did Prime Medicine (PRME) report on the Form 4 filed for Reine Allan?

The filing reports a one-time repricing of certain stock options held by Reine Allan, reducing the exercise price to $4.04 for 850,000 options.

How many options were repriced and to what exercise price?

A total of 850,000 option awards were repriced to an exercise price of $4.04 (previously $6.80).

When did the option repricing become effective for PRME?

The repricing is effective as of August 1, 2025, the date referenced as the "Repricing Date" in the filing.

Do the repriced options have modified vesting or expiration terms?

No. The filing states that, except for the exercise price, all other terms including vesting schedules and term remain in full force; expiration is shown as 01/17/2034.

Under which plans were the repriced options issued?

The repriced awards were issued under the company’s 2019 Stock Option and Grant Plan and/or the 2022 Stock Option and Incentive Plan.
Prime Medicine

NASDAQ:PRME

PRME Rankings

PRME Latest News

PRME Latest SEC Filings

PRME Stock Data

725.26M
102.56M
23.65%
53.86%
16.11%
Biotechnology
Biological Products, (no Disgnostic Substances)
Link
United States
CAMBRIDGE