STOCK TITAN

Pyxis Oncology (PYXS) director sells 35K shares after option exercise

Filing Impact
(Neutral)
Filing Sentiment
(Neutral)
Form Type
4

Rhea-AI Filing Summary

Pyxis Oncology director Jakob Dupont reported an exercise-and-sale of company stock. He exercised stock options covering 35,000 shares of common stock at an exercise price of $1.60 per share and received the underlying shares.

On the same date, he sold 35,000 common shares in open-market transactions at a weighted average price of $3.06 per share, with trade prices ranging from $3.00 to $3.36. These sales were carried out under a pre-arranged Rule 10b5-1 trading plan. After the transactions, Dupont holds 38,741 shares of Pyxis Oncology common stock directly.

Positive

  • None.

Negative

  • None.
Insider Dupont Jakob
Role null
Sold 35,000 shs ($107K)
Type Security Shares Price Value
Exercise Stock Option (Right to Buy) 35,000 $0.00 --
Exercise Common Stock 35,000 $1.60 $56K
Sale Common Stock 35,000 $3.06 $107K
Holdings After Transaction: Stock Option (Right to Buy) — 357,461 shares (Direct, null); Common Stock — 73,741 shares (Direct, null)
Footnotes (1)
  1. The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on Septemeber 24, 2025. Reflects sales of common stock executed in multiple transactions. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request by the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected within the ranges set forth in footnotes 3 of this Form 4. The transaction was executed in multiple trades in prices ranging from $3.00 to $3.36. Award of stock options to purchase Common Shares with a vesting commencement date of August 23, 2024. These options vest and become exercisable in three equal annual tranches from August 23, 2023, subject generally to the reporting person's continuous service through each vesting date (unless otherwise provided in the applicable award documentation).
Shares sold 35,000 shares Common stock sold in open market on June 30, 2026
Weighted average sale price $3.06 per share Common stock sale, trades between $3.00 and $3.36
Shares acquired via option exercise 35,000 shares Common stock received from stock option exercise
Option exercise price $1.60 per share Stock Option (Right to Buy) underlying common stock
Shares held after transactions 38,741 shares Direct common stock ownership following June 30, 2026 trades
Option expiration date September 22, 2033 Expiration of Stock Option (Right to Buy)
Sale price range $3.00–$3.36 per share Range of prices for multiple sale transactions
Rule 10b5-1 trading plan regulatory
"The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person"
A Rule 10b5-1 trading plan is a pre-arranged schedule that allows company insiders to buy or sell stock at specific times, even if they have inside information. It helps prevent accusations of unfair trading by making these transactions look planned and transparent, rather than sneaky or illegal.
weighted average sale price financial
"The price reported reflects the weighted average sale price."
Stock Option (Right to Buy) financial
"security_title": "Stock Option (Right to Buy)""
vesting commencement date financial
"Award of stock options to purchase Common Shares with a vesting commencement date of August 23, 2024."
The vesting commencement date is the starting point when an employee begins earning ownership rights to their promised benefits, such as stock options or retirement contributions. Think of it like the day a savings account is opened—only after this date do the benefits start to grow and become fully available over time. It matters to investors because it marks when the clock begins ticking toward full ownership, affecting the timing and value of these benefits.
derivative security financial
"transaction_code_description": "Exercise or conversion of derivative security""
A derivative security is a financial contract whose value comes from the price or performance of something else, such as a stock, bond, commodity, or market index. For investors it acts like an insurance policy or a wager: it can be used to protect against losses, lock in prices, or amplify gains and losses, so it can change a portfolio’s risk and potential return without owning the underlying asset directly.
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Learn about SEC filing dates
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Dupont Jakob

(Last)(First)(Middle)
C/O PYXIS ONCOLOGY, INC.
321 HARRISON AVENUE, 11TH FL. SUITE 1

(Street)
BOSTON MASSACHUSETTS 02118

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Pyxis Oncology, Inc. [ PYXS ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
Officer (give title below)Other (specify below)
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
06/30/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock06/30/2026M35,000A$1.673,741D
Common Stock06/30/2026S(1)35,000D$3.06(2)(3)38,741D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Option (Right to Buy)$1.606/30/2026M35,000 (4)09/22/2033Common Stock35,000$0357,461D
Explanation of Responses:
1. The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on Septemeber 24, 2025.
2. Reflects sales of common stock executed in multiple transactions. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request by the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected within the ranges set forth in footnotes 3 of this Form 4.
3. The transaction was executed in multiple trades in prices ranging from $3.00 to $3.36.
4. Award of stock options to purchase Common Shares with a vesting commencement date of August 23, 2024. These options vest and become exercisable in three equal annual tranches from August 23, 2023, subject generally to the reporting person's continuous service through each vesting date (unless otherwise provided in the applicable award documentation).
/s/ Jitendra Wadhane, Attorney-in-Fact for Jakob Dupont07/02/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What did Pyxis Oncology (PYXS) director Jakob Dupont report in this Form 4?

Director Jakob Dupont reported exercising stock options for 35,000 Pyxis Oncology shares at $1.60 and selling 35,000 shares at a weighted average price of $3.06. Following these transactions, he directly owns 38,741 shares of Pyxis Oncology common stock.

How many Pyxis Oncology (PYXS) shares did Jakob Dupont sell and at what price?

Jakob Dupont sold 35,000 shares of Pyxis Oncology common stock at a weighted average price of $3.06 per share. The sale was executed in multiple trades within a price range from $3.00 to $3.36 per share.

Were Jakob Dupont’s Pyxis Oncology (PYXS) share sales under a Rule 10b5-1 plan?

Yes. The filing states the sales were effected under a Rule 10b5-1 trading plan adopted by Jakob Dupont on September 24, 2025. Such plans pre-schedule trades, indicating these sales followed a pre-arranged program rather than being newly timed decisions.

What option exercise did Jakob Dupont report for Pyxis Oncology (PYXS)?

He exercised stock options to acquire 35,000 shares of Pyxis Oncology common stock at an exercise price of $1.60 per share. The related derivative entry shows a stock option to buy 35,000 shares with an expiration date of September 22, 2033.

How many Pyxis Oncology (PYXS) shares does Jakob Dupont hold after these transactions?

After completing the option exercise and subsequent sale, Jakob Dupont directly holds 38,741 shares of Pyxis Oncology common stock. This figure reflects his direct ownership immediately following the reported June 30, 2026 transactions in the Form 4.

What was the trading range for Jakob Dupont’s Pyxis Oncology (PYXS) share sales?

The reported sales were executed in multiple transactions at prices ranging from $3.00 to $3.36 per share. The Form 4 notes that the disclosed $3.06 price is a weighted average of these individual trades within the stated range.