Q32 Bio Inc. ownership update: Point72 Asset Management, Point72 Capital Advisors Inc., and Steven A. Cohen report shared voting and dispositive power over 958,768 shares of Common Stock, representing 5.7% of the class as of the close of business on May 14, 2026. The cover page footnote states that as of March 31, 2026 the reporting persons may have been deemed to beneficially own 0 shares. The filing attributes voting and investment power to Point72 Associates under an investment management agreement; Point72 Capital Advisors Inc. is the general partner and Mr. Cohen controls both entities.
Positive
None.
Negative
None.
Insights
Point72 reports a 5.7% shared position in Q32 Bio via managed fund.
Row 9 of the cover page lists 958,768 shares with shared voting and dispositive power reported as of May 14, 2026. The filing attributes ownership through Point72 Associates under an investment management agreement.
Implications depend on whether Point72 Associates trades or holds these shares; subsequent filings would show any changes in position or voting intent.
Control is reported via managed-account structure, not direct ownership.
The statement clarifies that Point72 Asset Management and Point72 Capital Advisors own no shares directly and report shared control over shares held by Point72 Associates. The filing includes the statement that it should not be construed as an admission of beneficial ownership under Section 13.
Watch for any future amendments or Form 13D/13G changes that disclose shifts in intent or additional control language.
Key Figures
Shared voting/dispositive power:958,768 sharesPercent of class:5.7%CUSIP:746964105+2 more
5 metrics
Shared voting/dispositive power958,768 sharesas of May 14, 2026
Percent of class5.7%as of May 14, 2026
CUSIP746964105Common Stock, par $0.0001
Cover page snapshot dateMay 14, 2026information set forth on cover page
Footnote dateMarch 31, 2026footnote states may have been deemed to beneficially own 0 shares
"The information set forth on this cover page reflects information as of the close of business on May 14, 2026."
Beneficially own means having the economic rights and risks of a security—such as the right to receive dividends, sell the shares, or profit from price changes—whether or not your name appears on the official share register. Think of it like renting a car: you use it and reap the benefits even if the title lists someone else. Investors care because beneficial ownership determines who truly controls value, must be disclosed under securities rules, and can signal potential influence or trading activity that affects a stock’s price.
shared dispositive powerfinancial
"Shared Dispositive Power 958,768.00"
investment management agreementregulatory
"Pursuant to an investment management agreement, Point72 Asset Management maintains investment and voting power"
An investment management agreement is a written contract that hires a professional to make buying, selling and strategy decisions for an investment account or fund, and sets out their duties, fees, risk limits, performance measures and reporting requirements. It matters to investors because the agreement determines who controls the money, how much the service costs, what risks are allowed, and how success or failure is measured—think of it as the service contract that defines expectations and remedies for a hired portfolio manager.
Schedule 13G/Aregulatory
"This statement is filed by: (i) Point72 Asset Management ..."
A Schedule 13G/A is an amended public filing with the U.S. securities regulator that updates a previous Schedule 13G, disclosing when an individual or group holds a substantial (typically over 5%) stake in a company and is claiming a passive, non‑controlling intent. Investors monitor these updates because rising or falling holdings can signal changing confidence, potential future moves, or shifts in voting power — like watching a public ledger where large shareholders quietly adjust their positions.
Point72 reports shared voting and dispositive power over 958,768 shares, equal to 5.7% of the class as of May 14, 2026. This position is held through Point72 Associates, an investment fund managed by Point72.
Who holds the reported voting and investment power for these QTTB shares?
The filing states Point72 Asset Management maintains investment and voting power over shares held by Point72 Associates; Point72 Capital Advisors Inc. is the general partner and Steven A. Cohen controls both entities.
Does Point72 directly own the reported QTTB shares?
No. The filing explicitly says Point72 Asset Management, Point72 Capital Advisors Inc., and Mr. Cohen own no shares directly; the reported power arises from an investment management agreement with Point72 Associates.
What do the March 31, 2026 footnote figures show?
The cover page footnote states that as of March 31, 2026 the reporting persons may have been deemed to beneficially own 0 shares of Common Stock, representing 0% of shares outstanding at that time.
Where is the issuer’s principal executive office listed?
The filing lists Q32 Bio Inc.'s principal executive office at 830 Winter Street, MA 02451 and provides Point72's business office at 72 Cummings Point Road, Stamford, CT 06902.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 1)
Q32 Bio Inc.
(Name of Issuer)
Common Stock, par value $0.0001 per share
(Title of Class of Securities)
746964105
(CUSIP Number)
03/31/2026
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
schemaVersion:
SCHEDULE 13G
CUSIP Number(s):
746964105
1
Names of Reporting Persons
Point72 Asset Management, L.P.
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
958,768.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
958,768.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
958,768.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.7 %
12
Type of Reporting Person (See Instructions)
PN
Comment for Type of Reporting Person: The information set forth on this cover page reflects information as of the close of business on May 14, 2026. As of March 31, 2026, the Reporting Person may have been deemed to beneficially own 0 shares of Common Stock (as defined in Item 2(a)), representing 0% of the shares of Common Stock outstanding as of such time.
SCHEDULE 13G
CUSIP Number(s):
746964105
1
Names of Reporting Persons
Point72 Capital Advisors, Inc.
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
958,768.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
958,768.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
958,768.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.7 %
12
Type of Reporting Person (See Instructions)
CO
Comment for Type of Reporting Person: The information set forth on this cover page reflects information as of the close of business on May 14, 2026. As of March 31, 2026, the Reporting Person may have been deemed to beneficially own 0 shares of Common Stock, representing 0% of the shares of Common Stock outstanding as of such time.
SCHEDULE 13G
CUSIP Number(s):
746964105
1
Names of Reporting Persons
Steven A. Cohen
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED STATES
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
958,768.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
958,768.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
958,768.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.7 %
12
Type of Reporting Person (See Instructions)
IN
Comment for Type of Reporting Person: The information set forth on this cover page reflects information as of the close of business on May 14, 2026. As of March 31, 2026, the Reporting Person may have been deemed to beneficially own 0 shares of Common Stock, representing 0% of the shares of Common Stock outstanding as of such time.
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
Q32 Bio Inc.
(b)
Address of issuer's principal executive offices:
830 WINTER STREET, WALTHAM, MA 02451
Item 2.
(a)
Name of person filing:
This statement is filed by: (i) Point72 Asset Management, L.P. ("Point72 Asset Management") with respect to the shares of common stock, par value $0.0001 per share ("Common Stock"), of Q32 Bio Inc. held by Point72 Associates, LLC, an investment fund it manages ("Point72 Associates"); (ii) Point72 Capital Advisors, Inc. ("Point72 Capital Advisors Inc.") with respect to the shares of Common Stock held by Point72 Associates; and (iii) Steven A. Cohen ("Mr. Cohen") with respect to the shares of Common Stock beneficially owned by Point72 Asset Management and Point72 Capital Advisors Inc.
(b)
Address or principal business office or, if none, residence:
The address of the principal business office of Point72 Asset Management, Point72 Capital Advisors Inc., and Mr. Cohen is 72 Cummings Point Road, Stamford, CT 06902.
(c)
Citizenship:
Point72 Asset Management is a Delaware limited partnership. Point72 Capital Advisors Inc. is a Delaware corporation. Mr. Cohen is a United States citizen.
(d)
Title of class of securities:
Common Stock, par value $0.0001 per share
(e)
CUSIP No.:
746964105
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
The information required by Item 4(a) is set forth in Row 9 of the cover page for each of the Reporting Persons and is incorporated herein by reference. Such information is as of the close of business on May 14, 2026. Such information as of March 31, 2026, is set forth in the footnote on such cover page.
Point72 Asset Management, Point72 Capital Advisors Inc., and Mr. Cohen own directly no shares of Common Stock. Pursuant to an investment management agreement, Point72 Asset Management maintains investment and voting power with respect to the securities held by Point72 Associates. Point72 Capital Advisors Inc. is the general partner of Point72 Asset Management. Mr. Cohen controls each of Point72 Asset Management and Point72 Capital Advisors Inc. The filing of this statement should not be construed as an admission that any of the foregoing persons or any Reporting Person is, for the purposes of Section 13 of the Securities Exchange Act of 1934, the beneficial owner of the shares of Common Stock reported herein.
(b)
Percent of class:
5.7%
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
The information required by Item 4(c)(i) is set forth in Row 5 of the cover page for each of the Reporting Persons and is incorporated herein by reference. Such information is as of the close of business on May 14, 2026.
(ii) Shared power to vote or to direct the vote:
The information required by Item 4(c)(ii) is set forth in Row 6 of the cover page for each of the Reporting Persons and is incorporated herein by reference. Such information is as of the close of business on May 14, 2026.
(iii) Sole power to dispose or to direct the disposition of:
The information required by Item 4(c)(iii) is set forth in Row 7 of the cover page for each of the Reporting Persons and is incorporated herein by reference. Such information is as of the close of business on May 14, 2026.
(iv) Shared power to dispose or to direct the disposition of:
The information required by Item 4(c)(iv) is set forth in Row 8 of the cover page for each of the Reporting Persons and is incorporated herein by reference. Such information is as of the close of business on May 14, 2026.
Item 5.
Ownership of 5 Percent or Less of a Class.
Not Applicable
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required.
See Item 2(a). Point72 Associates has the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, more than 5 percent of the outstanding Common Stock.
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
Not Applicable
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
