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Rapport Therapeutics: Sofinnova buys 952K shares

The director may be deemed to share voting and dispositive power over entity-held shares, while disclaiming beneficial ownership except to the extent of any pecuniary interest.

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Form Type
4

Rhea-AI Filing Summary

Rapport Therapeutics, Inc. (RAPP) director James Healy reported four purchases of common stock on October 28, 2026, made by investment entities: Sofinnova Venture Partners XI, L.P. purchased 952,380 shares; SummitTX Master, SPC – SummitTX Apex SP – Healthcare 3 purchased 6,395; SummitTX Master, SPC – SummitTX Alpha SP – Healthcare 3 purchased 3,772; and SummitTX Pinnacle Master, L.P. – Healthcare 3 purchased 6,933. Each purchase was at $21 per share. The footnotes state that Healy may be deemed to share voting and dispositive power over the entities’ shares, but disclaims beneficial ownership except to the extent of his pecuniary interest, if any. No Rule 10b5-1 plan is reported.

Insights

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Insider HEALY JAMES
Role Director
Bought 969,480 shs ($20.36M)
Increase in Position 50.9%
Type Security Shares Price Value
Purchase Common Stock F1 952,380 $21.00 $20.00M
Purchase Common Stock F2 6,395 $21.00 $134K
Purchase Common Stock F3 3,772 $21.00 $79K
Purchase Common Stock F4 6,933 $21.00 $146K
Holdings After Transaction: Common Stock — 2,815,707 shares (Indirect, By Sofinnova Venture Partners XI, L.P.); Common Stock — 17,990 shares (Indirect, By SummitTX Master, SPC -SummitTX Apex SP - Healthcare 3); Common Stock — 14,924 shares (Indirect, By SummitTX Master, SPC - SummitTX Alpha SP - Healthcare 3); Common Stock — 25,267 shares (Indirect, By SummitTX Pinnacle Master, L.P. - Healthcare 3)
Holdings Before and After: Common Stock, 1,863,327 to 2,815,707 shares (Indirect, By Sofinnova Venture Partners XI, L.P.); Common Stock, 11,595 to 17,990 shares (Indirect, By SummitTX Master, SPC -SummitTX Apex SP - Healthcare 3); Common Stock, 11,152 to 14,924 shares (Indirect, By SummitTX Master, SPC - SummitTX Alpha SP - Healthcare 3); Common Stock, 18,334 to 25,267 shares (Indirect, By SummitTX Pinnacle Master, L.P. - Healthcare 3)
Other Insiders: 6 other insiders reported open-market purchases of this stock in the 30 days up to this filing.
Footnotes (4)
  1. F1. The shares are directly held by Sofinnova Venture Partners XI, L.P. ("SVP XI"). Sofinnova Management XI, L.P. ("SM XI LP") is the general partner of SVP XI and Sofinnova Management XI, L.L.C. ("SM XI") is the general partner of SM XI LP. The Reporting Person is a managing member of SM XI and may be deemed to share voting and dispositive power over the shares held by SVP XI. The Reporting Person disclaims beneficial ownership of such shares for purposes of Section 16 of the Exchange Act, except to the extent of his pecuniary interest therein, if any. This report shall not be deemed an admission that he is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose.
  2. F2. The shares are directly held by SummitTX Master, SPC - SummitTX Apex SP - Healthcare 3 (f/k/a Crestline Summit Master, SPC - Crestline Summit Apex SP) ("Apex SP"). Sofinnova BioEquities GP LLC ("BioEquities GP") is the general partner of Apex SP. The Reporting Person is a managing member of BioEquities GP and may be deemed to share voting and dispositive power over the shares held by Apex SP. The Reporting Person disclaims beneficial ownership of such shares for purposes of Section 16 of the Exchange Act, except to the extent of his pecuniary interest therein, if any. This report shall not be deemed an admission that he is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose.
  3. F3. The shares are directly held by SummitTX Master, SPC - SummitTX Alpha SP - Healthcare 3 (f/k/a Crestline Summit Master, SPC - PEAK SP) ("Alpha SP"). BioEquities GP is the general partner of Alpha SP. The Reporting Person is a managing member of BioEquities GP and may be deemed to share voting and dispositive power over the shares held by Alpha SP. The Reporting Person disclaims beneficial ownership of such shares for purposes of Section 16 of the Exchange Act, except to the extent of his pecuniary interest therein, if any. This report shall not be deemed an admission that he is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose.
  4. F4. The shares are directly held by SummitTX Pinnacle Master, L.P. - Healthcare 3 (f/k/a Crestline Summit Pinnacle Master, L.P.) ("Pinnacle LP"). BioEquities GP is the general partner of Pinnacle LP. The Reporting Person is a managing member of BioEquities GP and may be deemed to share voting and dispositive power over the shares held by Pinnacle LP. The Reporting Person disclaims beneficial ownership of such shares for purposes of Section 16 of the Exchange Act, except to the extent of his pecuniary interest therein, if any. This report shall not be deemed an admission that he is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose.
Sofinnova Venture Partners XI, L.P. purchase 952,380 shares purchased; 2,815,707 shares following transaction October 28, 2026
SummitTX Apex SP – Healthcare 3 purchase 6,395 shares purchased; 17,990 shares following transaction October 28, 2026
SummitTX Alpha SP – Healthcare 3 purchase 3,772 shares purchased; 14,924 shares following transaction October 28, 2026
SummitTX Pinnacle Master, L.P. – Healthcare 3 purchase 6,933 shares purchased; 25,267 shares following transaction October 28, 2026
Purchase price per share $21 per share All four purchases on October 28, 2026
beneficial ownership regulatory
"disclaims beneficial ownership"
Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.
voting and dispositive power regulatory
"share voting and dispositive power over the shares"
pecuniary interest regulatory
"extent of his pecuniary interest therein"
Section 16 of the Exchange Act regulatory
"for purposes of Section 16 of the Exchange Act"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

How many RAPP shares did entities linked to director James Healy purchase?

Four entities purchased shares on October 28, 2026, at $21 per share: Sofinnova Venture Partners XI, L.P. (952,380); SummitTX Master, SPC – SummitTX Apex SP – Healthcare 3 (6,395); SummitTX Master, SPC – SummitTX Alpha SP – Healthcare 3 (3,772); and SummitTX Pinnacle Master, L.P. – Healthcare 3 (6,933).

What holdings were reported after the RAPP purchases linked to James Healy?

After the reported transactions, Sofinnova Venture Partners XI, L.P. held 2,815,707 shares; SummitTX Master, SPC – SummitTX Apex SP – Healthcare 3 held 17,990; SummitTX Master, SPC – SummitTX Alpha SP – Healthcare 3 held 14,924; and SummitTX Pinnacle Master, L.P. – Healthcare 3 held 25,267.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
HEALY JAMES

(Last)(First)(Middle)
SOFINNOVA INVESTMENTS, INC.
3000 SAND HILL ROAD, BLDG. 3, SUITE 150

(Street)
MENLO PARK CALIFORNIA 94025

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Rapport Therapeutics, Inc. [ RAPP ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
Officer (give title below)Other (specify below)
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
10/28/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock10/28/2026P952,380A$212,815,707IBy Sofinnova Venture Partners XI, L.P.(1)
Common Stock10/28/2026P6,395A$2117,990IBy SummitTX Master, SPC -SummitTX Apex SP - Healthcare 3(2)
Common Stock10/28/2026P3,772A$2114,924IBy SummitTX Master, SPC - SummitTX Alpha SP - Healthcare 3(3)
Common Stock10/28/2026P6,933A$2125,267IBy SummitTX Pinnacle Master, L.P. - Healthcare 3(4)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Explanation of Responses:
1. The shares are directly held by Sofinnova Venture Partners XI, L.P. ("SVP XI"). Sofinnova Management XI, L.P. ("SM XI LP") is the general partner of SVP XI and Sofinnova Management XI, L.L.C. ("SM XI") is the general partner of SM XI LP. The Reporting Person is a managing member of SM XI and may be deemed to share voting and dispositive power over the shares held by SVP XI. The Reporting Person disclaims beneficial ownership of such shares for purposes of Section 16 of the Exchange Act, except to the extent of his pecuniary interest therein, if any. This report shall not be deemed an admission that he is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose.
2. The shares are directly held by SummitTX Master, SPC - SummitTX Apex SP - Healthcare 3 (f/k/a Crestline Summit Master, SPC - Crestline Summit Apex SP) ("Apex SP"). Sofinnova BioEquities GP LLC ("BioEquities GP") is the general partner of Apex SP. The Reporting Person is a managing member of BioEquities GP and may be deemed to share voting and dispositive power over the shares held by Apex SP. The Reporting Person disclaims beneficial ownership of such shares for purposes of Section 16 of the Exchange Act, except to the extent of his pecuniary interest therein, if any. This report shall not be deemed an admission that he is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose.
3. The shares are directly held by SummitTX Master, SPC - SummitTX Alpha SP - Healthcare 3 (f/k/a Crestline Summit Master, SPC - PEAK SP) ("Alpha SP"). BioEquities GP is the general partner of Alpha SP. The Reporting Person is a managing member of BioEquities GP and may be deemed to share voting and dispositive power over the shares held by Alpha SP. The Reporting Person disclaims beneficial ownership of such shares for purposes of Section 16 of the Exchange Act, except to the extent of his pecuniary interest therein, if any. This report shall not be deemed an admission that he is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose.
4. The shares are directly held by SummitTX Pinnacle Master, L.P. - Healthcare 3 (f/k/a Crestline Summit Pinnacle Master, L.P.) ("Pinnacle LP"). BioEquities GP is the general partner of Pinnacle LP. The Reporting Person is a managing member of BioEquities GP and may be deemed to share voting and dispositive power over the shares held by Pinnacle LP. The Reporting Person disclaims beneficial ownership of such shares for purposes of Section 16 of the Exchange Act, except to the extent of his pecuniary interest therein, if any. This report shall not be deemed an admission that he is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose.
/s/ Nathalie Auber, Attorney-in-Fact10/30/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

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