Welcome to our dedicated page for Arcus Bioscience SEC filings (Ticker: RCUS), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
The Arcus Biosciences, Inc. (NYSE: RCUS) SEC filings page on Stock Titan provides structured access to the company’s regulatory disclosures, including current reports on Form 8‑K and other key documents filed with the U.S. Securities and Exchange Commission. As a clinical-stage biopharmaceutical company focused on oncology and inflammatory and autoimmune diseases, Arcus uses SEC filings to report material clinical, financial and corporate events that can be important for investors analyzing RCUS stock.
Form 8‑K current reports frequently highlight significant developments in Arcus’s pipeline and capital structure. For example, 8‑K filings describe the discontinuation of the Phase 3 STAR‑221 trial and the Phase 2 EDGE‑Gastric study after an interim overall survival analysis showed no benefit for the domvanalimab plus zimberelimab and chemotherapy regimen compared with nivolumab plus chemotherapy. Other 8‑Ks detail updated data from the ARC‑20 Phase 1/1b study of casdatifan in metastatic clear cell renal cell carcinoma, including progression-free survival and response metrics, as well as safety findings.
Filings also cover financing and capital markets transactions. One Form 8‑K outlines an underwriting agreement for a public offering of common stock, including the number of shares sold, pricing and net proceeds. Another 8‑K describes a First Amendment to the company’s Loan and Security Agreement with Hercules Capital and other lenders, which restructures remaining term loan commitments into milestone-based tranches tied to Phase 3 data and potential FDA approval, extends the maturity date and adds performance covenants linked to market capitalization, qualified cash levels and potential net product revenue thresholds.
Investors can also use SEC filings to track collaboration and licensing arrangements, such as disclosures related to Arcus’s long-term collaboration with Gilead Sciences and its option and license agreement with Taiho Pharmaceutical. These documents may reference option exercises, milestone structures and rights to co-develop or commercialize investigational medicines like casdatifan, domvanalimab, zimberelimab and quemliclustat in specific territories.
Stock Titan’s interface surfaces these filings alongside AI-powered summaries that explain the practical implications of each document. Instead of parsing detailed legal language alone, readers can review concise explanations of how a loan amendment changes Arcus’s access to capital, what a trial discontinuation means for a particular program, or how a new data disclosure from a Phase 1/1b or Phase 3 study might influence the company’s development strategy. Real-time updates from EDGAR, combined with these AI insights, help users follow Arcus’s quarterly results, material clinical events, financing decisions and collaboration milestones directly from the underlying SEC record.
RCUS submitted a Rule 144 notice reporting a proposed sale of 77,793 shares of Common Stock on 05/06/2026 tied to a stock option exercise by the issuer. The filing also records recent disposals by Jennifer Jarrett: 53,826 shares on 04/23/2026 and 70,000 shares on 04/08/2026, with reported proceeds listed alongside each sale.
Arcus Biosciences reported a deeper quarterly loss as collaboration revenue declined while it continued funding late‑stage trials. For the three months ended March 31, 2026, total revenue was $17 million, down from $28 million a year earlier, mainly due to lower Gilead collaboration revenue.
Research and development expense held flat at $122 million, and general and administrative expense was $29 million. Net loss widened to $128 million, or $(1.02) per share, from $112 million. Cash, cash equivalents and marketable securities totaled $876 million, and the company believes this will fund operations until at least the second half of 2028.
Arcus highlighted pipeline and partnership changes, including discontinuation of the Phase 3 STAR‑121 lung cancer trial for futility and Gilead’s decision not to make the sixth‑anniversary option continuation payment, which will end Gilead’s broad option rights on July 14, 2026 while preserving certain time‑limited options.
Arcus Biosciences reported first-quarter 2026 revenue of $17 million, down from $28 million a year earlier, and a net loss of $128 million versus $112 million. Loss per share improved to $1.02 from $1.14 due to a higher share count.
The company ended March 31, 2026 with $876 million in cash, cash equivalents and marketable securities and expects this to fund operations until at least the second half of 2028, targeting about $600 million in cash at year-end 2026. Management is prioritizing development of casdatifan in clear cell renal cell carcinoma, advancing multiple Phase 3 and Phase 1/1b studies, while expanding an emerging inflammation and immunology portfolio.
Arcus highlighted completion of enrollment in the Phase 3 PRISM-1 study of quemliclustat in first-line metastatic pancreatic cancer, but also disclosed discontinuation of the domvanalimab-based STAR-121 and EDGE-Lung lung cancer studies after a futility analysis showed no overall survival benefit over pembrolizumab plus chemotherapy.
RCUS insider filing: A Form 144 notice reports a proposed sale of 53,826 shares of Common Stock tied to a stock option exercise dated 04/23/2026. The filing also records a prior sale of 70,000 shares on 04/08/2026 for $1,579,592.00.
Arcus Biosciences is holding its 2026 Annual Meeting as a fully virtual event on June 11, 2026, at 8:30 a.m. Pacific Time. Stockholders of record as of April 16, 2026, when 125,628,682 common shares were outstanding and entitled to vote, may participate online.
Investors will vote on three items: electing four Class II directors to serve until the 2029 meeting, ratifying Ernst & Young LLP as independent auditor for the 2026 fiscal year, and approving on an advisory basis the compensation of named executive officers. The board recommends voting in favor of all three proposals.
The filing outlines Arcus’s governance structure, including a majority-independent board, a lead independent director, specialized audit, compensation, nominating, and science committees, and policies such as a clawback policy, equity administration policy, and insider trading restrictions.
Arcus Biosciences reported that the Phase 3 STAR-121 study in first-line metastatic non-small cell lung cancer, conducted with Gilead Sciences, has been discontinued for futility based on an Independent Data Monitoring Committee recommendation after a pre-planned futility analysis. Safety was not reassessed in that analysis, and no new safety issues have emerged in ongoing IDMC safety reviews. The related Phase 2 EDGE-Lung study will also be discontinued. The study’s exploratory arm showed zimberelimab plus chemotherapy delivering overall survival consistent with pembrolizumab plus chemotherapy.
Arcus also disclosed that Gilead will allow its broader option period to lapse on July 14, 2026 by not making an option continuation payment. Gilead will lose option rights to early-stage programs such as CCR6, CD89 and CD40L, but retains time-limited options to AB801, AB598, AB102 and an investigational TNF small molecule inhibitor. Arcus continues to hold full rights to casdatifan globally except for rights previously licensed to Taiho in Japan and certain other Asian territories, excluding China.
Arcus Biosciences Inc amended a Schedule 13G/A to report that The Vanguard Group holds 0 shares of Common Stock, representing 0% of the class. The filing explains an internal realignment on January 12, 2026, after which certain Vanguard subsidiaries report beneficial ownership separately.
The filing is signed by Ashley Grim, Head of Global Fund Administration, dated 03/26/2026.
Arcus Biosciences, Inc. reported that Chief Operating Officer Jennifer Jarrett has decided to resign from her role effective March 30, 2026. The company states that her resignation is not due to any disagreement over operations, policies, or practices.
Jarrett has entered into a separation agreement under which she will provide periodic advisory services through June 30, 2026, helping support continuity during the transition. In return, Arcus agreed to extend the period during which she may exercise any vested stock options to twelve months after termination, and the agreement includes a standard release of claims. The final separation agreement will be filed with the company’s next quarterly Form 10-Q.