Welcome to our dedicated page for Repligen SEC filings (Ticker: RGEN), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
Repligen Corporation's SEC filings document financial reporting, governance and public-company capital structure for a Nasdaq-listed life sciences company in bioprocessing technology. Recent Form 8-K reports attach earnings releases for quarterly and annual results, financial guidance and non-GAAP measures such as organic revenue, adjusted operating income, adjusted EPS and adjusted EBITDA.
The filing record also includes definitive proxy materials covering board matters, executive compensation and equity awards, along with Form 8-K disclosures on officer appointments, principal accounting officer responsibilities, financial reporting oversight and Sarbanes-Oxley-related infrastructure. Securities registration disclosures identify RGEN common stock, par value $0.01 per share, on the Nasdaq Global Select Market.
Repligen Corporation reported strong fourth-quarter and full-year 2025 results and issued upbeat 2026 guidance. Q4 2025 revenue reached $198 million, up 18% year over year (14% organic). Full-year 2025 revenue was $738 million, a 16% increase with 14% organic growth.
Profitability improved sharply. Full-year GAAP income from operations was $55 million versus a loss of $35 million in 2024, while GAAP net income was $48.9 million compared to a $25.5 million loss. Adjusted net income rose to $96.9 million, with adjusted diluted EPS of $1.71 versus $1.58.
Margins expanded, with 2025 GAAP gross margin at 52.3% and adjusted operating margin at 13.8%. For 2026, Repligen guides revenue of $810–$840 million (10–14% reported growth, 9–13% organic), adjusted operating margin of 15.1–15.5%, adjusted EBITDA margin of 20–20.5%, and diluted EPS of $1.93–$2.01. Cash, cash equivalents and marketable securities totaled $768 million at December 31, 2025.
T. Rowe Price Associates, Inc. filed an amended Schedule 13G reporting a significant ownership position in Repligen Corp. common stock. The firm reports beneficial ownership of 4,599,860 shares, representing 8.2% of the outstanding common stock as of December 31, 2025.
T. Rowe Price states it has sole voting power over 4,301,925 shares and sole dispositive power over 4,599,061 shares, with no shared voting or dispositive power. It certifies the shares were acquired and are held in the ordinary course of business and not for the purpose of influencing control of Repligen.
Repligen Corporation’s common stock ownership has been updated by several Eddleman-related trusts in an amended Schedule 13G.
The Roy T. Eddleman Living Trust reports beneficial ownership of 2,705,689 shares of Repligen common stock, representing 4.81% of the class. The Roy T. Eddleman Charitable Remainder Trust #1 reports beneficial ownership of 29,604 shares, representing 0.001% of the class, while Charitable Remainder Trust #2 reports no shares. Co‑trustees Geoffrey Paul, Nereyda Rubio and Anis Garci share voting and investment power over a total of 2,735,293 shares. The filing states these securities are held on a passive basis and not for the purpose of changing or influencing control of Repligen.
FMR LLC and Abigail P. Johnson report a 5.1% beneficial stake in Repligen Corp common stock. As of December 31, 2025, they report beneficial ownership of 2,891,140.17 shares, representing 5.1% of the outstanding common stock. FMR LLC has sole voting power over 2,876,401.55 shares and sole dispositive power over 2,891,140.17 shares, while Abigail P. Johnson has sole dispositive power over the same 2,891,140.17 shares with no voting power. The securities are certified as being held in the ordinary course of business and not for the purpose of changing or influencing control of Repligen. One or more other persons may have rights to dividends or sale proceeds, but no single such interest exceeds five percent of the class.
Repligen Corporation reported new equity awards to its Chief Product Officer, Douglass Brian Robb. On 12/31/2025, he received 2,288 restricted stock units, each representing one share of Repligen common stock. These restricted stock units vest in substantially equal annual installments over three years, beginning on the first anniversary of the grant date, and are settled only in shares of common stock.
On the same date, he was also granted a stock option for 2,143 shares of common stock at an exercise price of $163.86 per share, expiring on 12/31/2035. Following the restricted stock award, he directly beneficially owned 8,540 shares of common stock, and 2,143 stock options were beneficially owned directly after the option grant.
Repligen Corporation’s Chief Product Officer, Douglass Brian Robb, reported his beneficial ownership as of December 31, 2025. He directly holds 6,252 shares of Repligen common stock, which include restricted stock units granted on May 7, 2024 (4,000 units vesting in equal annual installments over five years) and on March 1, 2025 (2,252 units vesting in equal annual installments over four years).
He also holds two stock option awards, each exercisable for Repligen common stock at an exercise price of $167.72 per share and expiring on May 7, 2034: one covering 2,980 shares, with 596 shares already vested and the remainder vesting annually from May 7, 2026 through May 7, 2029, and another covering 7,020 shares, with 1,404 shares vested and the rest vesting on the same schedule. All reported holdings are listed as directly owned.
A director of Repligen Corp (RGEN) reported a small open-market sale of company stock. On 12/17/2025, the director sold 275 shares of Repligen common stock at a price of $161 per share, as shown in Table I of the filing. After this transaction, the director continued to beneficially own 91,821 shares of Repligen common stock, held as a direct ownership position. The report was filed as a Form 4 for one reporting person, indicating routine insider transaction disclosure.
Repligen Corporation reported that one of its directors exercised a stock option for common shares. On 12/16/2025, the director acquired 3,366 shares of common stock through an option exercise at a price of $26.12 per share, increasing the director’s direct beneficial ownership to 36,622 common shares after the transaction. The related stock option, which is fully vested and exercisable, covers 3,366 shares of common stock and carries an exercise price of $26.12 with an expiration date of May 11, 2026.
A director of Repligen Corporation reported an insider transfer of 2,000 shares of Repligen common stock on 12/04/2025. After this transaction, the reporting person beneficially owns 98,959 shares of common stock in direct form. The filing describes the move as a transfer of shares in which the reporting person is a joint tenant with right of survivorship, indicating a change in how the shares are held rather than a typical market sale.
Repligen Corporation (RGEN) reported an insider stock sale by its Chief Executive Officer, who is also a director. On 11/25/2025, the executive sold 7,041 shares of common stock at a price of $170 per share, as shown in a Form 4 filing. After this transaction, the executive directly held 35,898 shares of Repligen common stock.
The sale was carried out under a pre-arranged Rule 10b5-1 trading plan that was adopted on December 12, 2024, which is designed to allow insiders to sell shares according to a set schedule.