STOCK TITAN

[Form 4] Revolution Medicines, Inc. Insider Trading Activity

Filing Impact
(High)
Filing Sentiment
(Negative)
Form Type
4

Mark A. Goldsmith, President and Chief Executive Officer of Revolution Medicines, reported a sale of 13,411 shares of the issuer's common stock on 09/16/2025 at a reported price of $45.8249 per share. The filing states the sale was made pursuant to a Rule 10b5-1 instruction letter adopted May 31, 2023 to satisfy the reporting person’s tax withholding obligation upon RSU vesting.

Following the reported transaction, the filing shows 452,309 shares beneficially owned directly, and additional indirect holdings of 20,424, 20,424, and 465,604 shares held by three trusts. The form is signed by an attorney-in-fact on behalf of Mr. Goldsmith.

Mark A. Goldsmith, presidente e amministratore delegato di Revolution Medicines, ha riferito la vendita di 13.411 azioni ordinarie dell'emittente il 16/09/2025 a un prezzo riportato di 45,8249$ per azione. La compilazione indica che la vendita è stata effettuata ai sensi di una lettera di istruzioni Rule 10b5-1 adottata il 31 maggio 2023 per soddisfare l'obbligo di ritenuta fiscale del soggetto segnalante al vesting degli RSU. A seguito della transazione segnalata, la compilazione mostra che detiene direttamente 452.309 azioni in modo beneficiante, e ulteriori detenzioni indirette di 20.424, 20.424, e 465.604 azioni detenute da tre trust. Il modulo è firmato da un procuratore-in-fatto per conto del Signor Goldsmith.

Mark A. Goldsmith, presidente y director ejecutivo de Revolution Medicines, informó la venta de 13,411 acciones ordinarias del emisor el 16/09/2025 a un precio reportado de 45,8249$ por acción. El archivo indica que la venta se realizó conforme a una carta de instrucciones Rule 10b5-1 adoptada el 31 de mayo de 2023 para cumplir la obligación de retención de impuestos del informante al vesting de las RSU. Tras la operación reportada, el archivo muestra que posee directamente 452.309 acciones beneficia de manera directa, y participaciones indirectas adicionales de 20.424, 20.424 y 465.604 acciones en tres fideicomisos. El formulario está firmado por un apoderado en nombre del Sr. Goldsmith.

Mark A. Goldsmith, Revolution Medicines의 회장 겸 최고경영자, 2025년 9월 16일에 일반주 13,411주를 매도하였으며 주당 보고 가격은 45.8249달러로 보고되었습니다. 제출서는 RSU의 vesting에 따른 납세 withholding 의무를 충족하기 위해 2023년 5월 31일에 채택된 Rule 10b5-1 지시서에 따라 매도가 이루어졌다고 명시합니다. 보고된 거래 이후 제출서는 직접 소유한 이익실현 주식 452,309주와 20,424주, 20,424주, 465,604주 등 세 신탁이 보유한 간접 주식이 추가로 있음을 보여줍니다. 양식은 Goldsmith 씨를 대신하여 법정대리인이 서명했습니다.

Mark A. Goldsmith, président et directeur général de Revolution Medicines, a déclaré la vente de 13 411 actions ordinaires de l’émetteur le 16/09/2025 à un prix déclaré de 45,8249$ par action. Le dépôt indique que la vente a été réalisée en vertu d’une lettre d’instructions Rule 10b5-1 adoptée le 31 mai 2023 pour satisfaire l’obligation de retenue fiscale de la personne déclarant lors du vesting des RSU. Après la transaction signalée, le dossier indique que le détenteur bénéficie directement de 452 309 actions et des positions indirectes supplémentaires de 20 424, 20 424 et 465 604 actions détenues par trois fidéicomisses. Le formulaire est signé par un mandataire agissant au nom de M. Goldsmith.

Mark A. Goldsmith, Präsident und Chief Executive Officer von Revolution Medicines, meldete den Verkauf von 13.411 Stammaktien des Emittenten am 16.09.2025 zu einem angegebenen Kurs von 45,8249 USD pro Aktie. Die Einreichung besagt, dass der Verkauf gemäß einem am 31. Mai 2023 angenommenen Rule-10b5-1-Anweisungsverzeichnis erfolgt sei, um die steuerliche Abzugspflicht der meldenden Person bei RSU-Vesting zu erfüllen. Nach der gemeldeten Transaktion zeigt die Einreichung, dass direkt und wirtschaftlich 452.309 Aktien gehalten werden, sowie zusätzliche indirekte Bestände von 20.424, 20.424 und 465.604 Aktien, gehalten von drei Trusts. Das Formular ist von einem Bevollmächtigten im Namen von Herrn Goldsmith unterzeichnet.

أعلن Mark A. Goldsmith، رئيس مجلس الإدارة والمدير التنفيذي لشركة Revolution Medicines، عن بيع 13,411 سهماً من الأسهم العادية للمصدر في 16/09/2025 بسعر تقريبي 45.8249 دولاراً للسهم. وتذكر الوثيقة أن البيع تم بموجب خطاب تعليمات Rule 10b5-1 اعتمد في 31 مايو 2023 لتلبية التزام الاحتجاز الضريبي للشخص المبلغ عنه عند استحقاق RSU. وبعد الصفقة المبلغ عنها، يظهر الملف أن الملكية مباشرةً تبلغ 452,309 سهماً، إضافة إلى حصص غير مباشرة إضافية بقيمة 20,424 و20,424 و465,604 سهماً مملوكة لثلاثة صناديق ائتمانية. النموذج موقع من وكيل نيابة نيابةً باسم السيد Goldsmith.

Mark A. Goldsmith, Revolution Medicines 的总裁兼首席执行官,报道在 2025-09-16 出售了 13,411 股发行人普通股,披露价为每股 45.8249 美元。该备案称该出售是根据于 2023 年 5 月 31 日通过的 Rule 10b5-1 指示函执行,以满足报告人就 RSU 的归属时的税收扣缴义务。报告交易后,备案显示直接受益持有 452,309 股,以及由三家信托间接持有的额外 20,424、20,424 和 465,604 股。该表格由代表 Goldsmith 先生的代理人签署。

Positive
  • Transaction executed under a Rule 10b5-1 plan, indicating pre-established, compliant trading for tax withholding
  • Timely disclosure filed on Form 4 and signed by an authorized attorney-in-fact
  • Insider retains substantial ownership with combined direct and indirect holdings reported in the filing
Negative
  • Reported sale of 13,411 shares reduces the reporting person’s direct holdings
  • Price-sensitive transaction could be interpreted by some investors as insider liquidity, though context is provided

Insights

TL;DR: Insider sale appears routine tax-withholding under a pre-established 10b5-1 plan and is not an explicit signal of company performance.

The transaction discloses a sale of 13,411 shares at $45.8249 executed under a Rule 10b5-1 plan to satisfy taxes on vested RSUs. Such automated plans are commonly used to avoid timing issues and reduce perception of opportunistic trading. The sale represents a small fraction of the reporting person's combined direct and indirect holdings, which total over 900,000 shares across listed accounts and trusts, so the impact on ownership percentage is limited. No derivative transactions or other compensatory awards are reported on this form.

TL;DR: Disclosure demonstrates governance compliance through Rule 10b5-1 execution and timely Section 16 reporting.

The Form 4 clearly states the sale was pursuant to a 10b5-1 instruction adopted May 31, 2023, which supports pre-established, rule-compliant trading. The filing includes detailed indirect ownership via three trusts and is signed by an attorney-in-fact, indicating delegated execution and proper documentation. There are no indications of unusual related-party transfers or sudden changes in compensation structure on this filing.

Mark A. Goldsmith, presidente e amministratore delegato di Revolution Medicines, ha riferito la vendita di 13.411 azioni ordinarie dell'emittente il 16/09/2025 a un prezzo riportato di 45,8249$ per azione. La compilazione indica che la vendita è stata effettuata ai sensi di una lettera di istruzioni Rule 10b5-1 adottata il 31 maggio 2023 per soddisfare l'obbligo di ritenuta fiscale del soggetto segnalante al vesting degli RSU. A seguito della transazione segnalata, la compilazione mostra che detiene direttamente 452.309 azioni in modo beneficiante, e ulteriori detenzioni indirette di 20.424, 20.424, e 465.604 azioni detenute da tre trust. Il modulo è firmato da un procuratore-in-fatto per conto del Signor Goldsmith.

Mark A. Goldsmith, presidente y director ejecutivo de Revolution Medicines, informó la venta de 13,411 acciones ordinarias del emisor el 16/09/2025 a un precio reportado de 45,8249$ por acción. El archivo indica que la venta se realizó conforme a una carta de instrucciones Rule 10b5-1 adoptada el 31 de mayo de 2023 para cumplir la obligación de retención de impuestos del informante al vesting de las RSU. Tras la operación reportada, el archivo muestra que posee directamente 452.309 acciones beneficia de manera directa, y participaciones indirectas adicionales de 20.424, 20.424 y 465.604 acciones en tres fideicomisos. El formulario está firmado por un apoderado en nombre del Sr. Goldsmith.

Mark A. Goldsmith, Revolution Medicines의 회장 겸 최고경영자, 2025년 9월 16일에 일반주 13,411주를 매도하였으며 주당 보고 가격은 45.8249달러로 보고되었습니다. 제출서는 RSU의 vesting에 따른 납세 withholding 의무를 충족하기 위해 2023년 5월 31일에 채택된 Rule 10b5-1 지시서에 따라 매도가 이루어졌다고 명시합니다. 보고된 거래 이후 제출서는 직접 소유한 이익실현 주식 452,309주와 20,424주, 20,424주, 465,604주 등 세 신탁이 보유한 간접 주식이 추가로 있음을 보여줍니다. 양식은 Goldsmith 씨를 대신하여 법정대리인이 서명했습니다.

Mark A. Goldsmith, président et directeur général de Revolution Medicines, a déclaré la vente de 13 411 actions ordinaires de l’émetteur le 16/09/2025 à un prix déclaré de 45,8249$ par action. Le dépôt indique que la vente a été réalisée en vertu d’une lettre d’instructions Rule 10b5-1 adoptée le 31 mai 2023 pour satisfaire l’obligation de retenue fiscale de la personne déclarant lors du vesting des RSU. Après la transaction signalée, le dossier indique que le détenteur bénéficie directement de 452 309 actions et des positions indirectes supplémentaires de 20 424, 20 424 et 465 604 actions détenues par trois fidéicomisses. Le formulaire est signé par un mandataire agissant au nom de M. Goldsmith.

Mark A. Goldsmith, Präsident und Chief Executive Officer von Revolution Medicines, meldete den Verkauf von 13.411 Stammaktien des Emittenten am 16.09.2025 zu einem angegebenen Kurs von 45,8249 USD pro Aktie. Die Einreichung besagt, dass der Verkauf gemäß einem am 31. Mai 2023 angenommenen Rule-10b5-1-Anweisungsverzeichnis erfolgt sei, um die steuerliche Abzugspflicht der meldenden Person bei RSU-Vesting zu erfüllen. Nach der gemeldeten Transaktion zeigt die Einreichung, dass direkt und wirtschaftlich 452.309 Aktien gehalten werden, sowie zusätzliche indirekte Bestände von 20.424, 20.424 und 465.604 Aktien, gehalten von drei Trusts. Das Formular ist von einem Bevollmächtigten im Namen von Herrn Goldsmith unterzeichnet.

SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Estimated average burden
hours per response: 0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
1. Name and Address of Reporting Person*
GOLDSMITH MARK A

(Last) (First) (Middle)
C/O REVOLUTION MEDICINES, INC.
700 SAGINAW DRIVE

(Street)
REDWOOD CITY CA 94063

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
Revolution Medicines, Inc. [ RVMD ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
X Director 10% Owner
X Officer (give title below) Other (specify below)
See Remarks
3. Date of Earliest Transaction (Month/Day/Year)
09/16/2025
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 09/16/2025 S(1) 13,411 D $45.8249 452,309(2) D
Common Stock 20,424 I Trust(3)
Common Stock 20,424 I Trust(4)
Common Stock 465,604 I Trust(5)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Explanation of Responses:
1. Transaction made pursuant to a Rule 10b5-1 instruction letter adopted on May 31, 2023 to satisfy the Reporting Person's tax withholding obligation upon the vesting of restricted stock units ("RSUs") after July 15, 2023.
2. Includes 193,475 restricted stock units.
3. Held by Jonathan Goldsmith Revocable Trust.
4. Held by Rebecca Eve Goldsmith Trust under the Goldsmith Children's 2011 Irrevocable Education Trust, dated December 15, 2011.
5. Held by Mark A. Goldsmith and Anne E. Midler 2002 Revocable Living Trust.
Remarks:
President and Chief Executive Officer
/s/ Jack Anders, as attorney-in fact for Mark A. Goldsmith 09/18/2025
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What did Mark A. Goldsmith report on Form 4 for Revolution Medicines (RVMD)?

The Form 4 reports a sale of 13,411 common shares on 09/16/2025 at $45.8249 per share by Mark A. Goldsmith.

Why was the sale made according to the Form 4 filing?

The sale was made pursuant to a Rule 10b5-1 instruction adopted May 31, 2023 to satisfy the reporting person’s tax withholding obligation upon RSU vesting.

How many shares does the reporting person beneficially own after the transaction?

The filing shows 452,309 shares beneficially owned directly after the transaction, plus indirect holdings of 20,424, 20,424, and 465,604 in three trusts.

Was any derivative or option transaction reported on this Form 4?

No. The Form 4 contains only non-derivative common stock transactions and does not report any derivative securities.

Who signed the Form 4 and when?

The Form 4 was signed by Jack Anders as attorney-in-fact for Mark A. Goldsmith on 09/18/2025.
Revolution

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11.04M
Biological Products, (no Disgnostic Substances)
REDWOOD CITY