SCYNEXIS (SCYX) investors CVI and Heights disclose 5.9% ownership stake

Rhea-AI Filing Summary

SCYNEXIS, Inc. received an amended Schedule 13G from CVI Investments, Inc. and Heights Capital Management, Inc., reporting beneficial ownership of SCYNEXIS common stock. The Reporting Persons collectively report beneficial ownership of 615,522 Shares, representing 5.9% of the outstanding common stock as of June 30, 2026.

The position consists of 150,551 Shares of common stock and additional Shares issuable upon exercise of warrants, which are subject to 4.99% and 9.99% beneficial ownership limitations. Heights Capital Management, Inc. is the investment manager to CVI Investments, Inc. and may exercise shared voting and dispositive power over these Shares, while both entities disclaim beneficial ownership beyond their pecuniary interest.

Key Figures

Beneficially owned Shares: 615,522 Shares Percent of class: 5.9% Shares outstanding: 9,949,609 Shares +4 more

7 metrics

Beneficially owned Shares 615,522 Shares Shares beneficially owned by the Reporting Persons under Schedule 13G/A

Percent of class 5.9% Percentage of SCYNEXIS common stock beneficially owned

Shares outstanding 9,949,609 Shares SCYNEXIS common stock outstanding as of June 30, 2026

Common Shares held 150,551 Shares Portion of beneficial ownership in actual common stock, excluding warrants

Lower ownership cap 4.99% Beneficial ownership limitation on a portion of the warrants

Higher ownership cap 9.99% Beneficial ownership limitation on the remainder of the warrants

Reporting date reference June 30, 2026 Date for outstanding Shares per Form 10-Q used in ownership calculation

Key Terms

beneficial owner, dispositive power, Section 13(d), pecuniary interest, +1 more

5 terms

beneficial owner financial

"may be deemed to be the beneficial owner of all Shares owned"

A beneficial owner is the person who ultimately owns or controls a financial asset or property, even if their name isn't directly on official documents. Think of it like someone who secretly holds the keys to a safe deposit box—others may appear to have access, but the true owner is the one who benefits from what's inside. Identifying beneficial owners helps ensure transparency and prevent illegal activities like money laundering or fraud.

dispositive power financial

"Shared Dispositive Power 615,522.00"

Dispositive power is the authority to decide the final outcome of an asset, legal claim, contract, or corporate action — in effect the power to dispose of or resolve something. For investors it matters because whoever holds that authority can determine who gets paid, who controls an asset or vote, and how risks and returns are allocated; think of it like holding the key that lets you lock in the winner or loser in a deal.

Section 13(d) regulatory

"aggregated with such Reporting Person for purposes of Section 13(d) of the Exchange Act"

pecuniary interest financial

"disclaims any beneficial ownership of any such Shares, except for their pecuniary interest therein"

Limited Power of Attorney regulatory

"serves as authorized agent of CVI Investments, Inc. pursuant to a Limited Power of Attorney"

FAQ

What ownership stake in SCYX do CVI Investments and Heights Capital report?

CVI Investments and Heights Capital report beneficial ownership of 615,522 Shares of SCYNEXIS common stock, representing 5.9% of the class, based on 9,949,609 Shares outstanding as of June 30, 2026, per the company’s Form 10-Q.

How is the 615,522-share SCYX position held by the reporting persons composed?

The reported 615,522 Shares consist of 150,551 Shares of SCYNEXIS common stock and additional Shares issuable upon exercise of warrants. Some warrants are subject to 4.99% and others to 9.99% beneficial ownership caps.

What beneficial ownership limitations apply to the SCYX warrants held?

The warrants are not exercisable if exercise would cause total beneficial ownership to exceed 4.99% for a portion of the warrants and 9.99% for the remainder, calculated together with affiliates and other aggregated holders under Section 13(d) of the Exchange Act.

What role does Heights Capital Management play in the SCYX holdings?

Heights Capital Management, Inc. acts as investment manager to CVI Investments, Inc. and may exercise shared voting and dispositive power over 615,522 Shares. Each reporting person disclaims beneficial ownership beyond its pecuniary interest in the Shares.

What is the SCYNEXIS share count used to calculate the 5.9% ownership?

The 5.9% ownership is calculated using 9,949,609 Shares of SCYNEXIS common stock outstanding as of June 30, 2026, as stated in the company’s Quarterly Report on Form 10-Q filed on August 10, 2026.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 08/14/2026 - 02:45 PM Accepted by SEC EDGAR 08/14/2026 - 02:44 PM Learn about SEC filing dates

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 2)

SCYNEXIS, Inc.

(Name of Issuer)

Common Stock, $0.001 par value per share

(Title of Class of Securities)

811292309

(CUSIP Number)

06/30/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

schemaVersion:

SCHEDULE 13G

CUSIP Number(s): 811292309

1

Names of Reporting Persons

CVI Investments, Inc.

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

CAYMAN ISLANDS

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 615,522.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 615,522.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

615,522.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

5.9 %

12

Type of Reporting Person (See Instructions)

CO

Comment for Type of Reporting Person: With respect to Row 6 and Row 8 above, Heights Capital Management, Inc. is the investment manager to CVI Investments, Inc. and as such may exercise voting and dispositive power over the shares reported as beneficially owned by CVI Investments, Inc. herein.

SCHEDULE 13G

CUSIP Number(s): 811292309

1

Names of Reporting Persons

Heights Capital Management, Inc.

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 615,522.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 615,522.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

615,522.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

5.9 %

12

Type of Reporting Person (See Instructions)

CO

Comment for Type of Reporting Person: With respect to Row 6 and Row 8 above, Heights Capital Management, Inc. is the investment manager to CVI Investments, Inc. and as such may exercise voting and dispositive power over the shares reported as beneficially owned by CVI Investments, Inc. herein.

SCHEDULE 13G

Item 1.
(a)	Name of issuer: SCYNEXIS, Inc.
(b)	Address of issuer's principal executive offices: 1 Evertrust Plaza, 13th Floor, Jersey City, NJ 07302-6548
Item 2.
(a)	Name of person filing: This statement is filed by the entities listed below, who are collectively referred to herein as "Reporting Persons," with respect to the shares of common stock of SCYNEXIS, Inc. (the "Company"), $0.001 par value per share (the "Shares"). (i) CVI Investments, Inc. (ii) Heights Capital Management, Inc.
(b)	Address or principal business office or, if none, residence: The address of the principal business office of CVI Investments, Inc. is: P.O. Box 309GT Ugland House South Church Street George Town Grand Cayman KY1-1104 Cayman Islands The address of the principal business office of Heights Capital Management, Inc. is: 101 California Street, Suite 3250 San Francisco, California 94111
(c)	Citizenship: Citizenship is set forth in Row 4 of the cover page for each Reporting Person hereto and is incorporated herein by reference for each such Reporting Person.
(d)	Title of class of securities: Common Stock, $0.001 par value per share
(e)	CUSIP No.: 811292309
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: The information required by this Item 4(a) is set forth in Row 9 of the cover page for each Reporting Person hereto and is incorporated herein by reference for each such Reporting Person. The number of Shares reported as beneficially owned consists of (i) 150,551 Shares, and (ii) Shares issuable upon the exercise of warrants to purchase Shares (the "Warrants"). A portion of the Warrants are not exercisable to the extent that the total number of Shares then beneficially owned by a Reporting Person and its affiliates and any other persons whose beneficial ownership of Shares would be aggregated with such Reporting Person for purposes of Section 13(d) of the Exchange Act, would exceed 4.99%, and the remainder of the Warrants are not exercisable to the extent that the total number of Shares then beneficially owned by a Reporting Person and its affiliates and any other persons whose beneficial ownership of Shares would be aggregated with such Reporting Person for purposes of Section 13(d) of the Exchange Act, would exceed 9.99%. The Company's Quarterly Report on Form 10-Q, filed on August 10, 2026, indicates there were 9,949,609 Shares outstanding as of June 30, 2026.
(b)	Percent of class: 5.9 %
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: The information required by this Item 4(c)(i) is set forth in Row 5 of the cover page for each Reporting Person hereto and is incorporated herein by reference for each such Reporting Person.
	(ii) Shared power to vote or to direct the vote: The information required by this Item 4(c)(ii) is set forth in Row 6 of the cover page for each Reporting Person hereto and is incorporated herein by reference for each such Reporting Person. Heights Capital Management, Inc., which serves as the investment manager to CVI Investments, Inc., may be deemed to be the beneficial owner of all Shares owned by CVI Investments, Inc. Each of the Reporting Persons hereby disclaims any beneficial ownership of any such Shares, except for their pecuniary interest therein.
	(iii) Sole power to dispose or to direct the disposition of: The information required by this Item 4(c)(iii) is set forth in Row 7 of the cover page for each Reporting Person hereto and is incorporated herein by reference for each such Reporting Person.
	(iv) Shared power to dispose or to direct the disposition of: The information required by this Item 4(c)(iv) is set forth in Row 8 of the cover page for each Reporting Person hereto and is incorporated herein by reference for each such Reporting Person. Heights Capital Management, Inc., which serves as the investment manager to CVI Investments, Inc., may be deemed to be the beneficial owner of all Shares owned by CVI Investments, Inc. Each of the Reporting Persons hereby disclaims any beneficial ownership of any such Shares, except for their pecuniary interest therein.
Item 5.	Ownership of 5 Percent or Less of a Class.
	Not Applicable
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	Not Applicable
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

CVI Investments, Inc.

Signature:	/s/ Sarah Travis
Name/Title:	Sarah Travis, Assistant General Counsel and Assistant Secretary of Heights Capital Management, Inc.
Date:	08/14/2026

Heights Capital Management, Inc.

Signature:	/s/ Sarah Travis
Name/Title:	Sarah Travis, Assistant General Counsel and Assistant Secretary
Date:	08/14/2026

Comments accompanying signature: Heights Capital Management, Inc. serves as authorized agent of CVI Investments, Inc. pursuant to a Limited Power of Attorney, a copy of which was previously filed.

Exhibit Information

EXHIBIT INDEX EXHIBIT DESCRIPTION 24 Limited Power of Attorney* 99 Joint Filing Agreement* * Previously filed